Homo sapiens

52 known processes

TNFRSF10B

tumor necrosis factor receptor superfamily, member 10b

(Aliases: TRICK2A,TRICK2B,TRICK2,CD262,KILLER,DR5,KILLER/DR5,ZTNFR9,TRAIL-R2,TRICKB,TRAILR2)

TNFRSF10B biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
trail activated apoptotic signaling pathway GO:0036462 4 1.000
Human
cellular response to increased oxygen levels GO:0036295 4 0.996
Human
response to hyperoxia GO:0055093 4 0.994
Human
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.989
programmed necrotic cell death GO:0097300 18 0.981
Human
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.978
Zebrafish
negative regulation of response to wounding GO:1903035 47 0.972
Human
positive regulation of release of cytochrome c from mitochondria GO:0090200 18 0.967
skeletal muscle satellite cell proliferation GO:0014841 1 0.962
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.957
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 28 0.955
Human
response to increased oxygen levels GO:0036296 4 0.955
Human
positive regulation of homotypic cell cell adhesion GO:0034112 4 0.942
regulation of cellular ketone metabolic process GO:0010565 50 0.931
zymogen activation GO:0031638 70 0.919
positive regulation of phosphorylation GO:0042327 394 0.913
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.906
extrinsic apoptotic signaling pathway GO:0097191 119 0.903
Human
cellular response to mechanical stimulus GO:0071260 39 0.893
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.889
regulation of tyrosine phosphorylation of stat1 protein GO:0042510 11 0.873
Human
necroptotic process GO:0070266 16 0.869
Human
t cell apoptotic process GO:0070231 12 0.858
cellular amino acid metabolic process GO:0006520 116 0.853
positive regulation of apoptotic process GO:0043065 246 0.851
Human Zebrafish
response to cobalt ion GO:0032025 1 0.848
regulation of cellular amino acid metabolic process GO:0006521 6 0.845
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.840
erk1 and erk2 cascade GO:0070371 104 0.838
positive regulation of myeloid leukocyte differentiation GO:0002763 24 0.835
leukocyte migration GO:0050900 107 0.827
regulation of defense response GO:0031347 154 0.826
Human
lymphocyte apoptotic process GO:0070227 20 0.823
regulation of tyrosine phosphorylation of stat protein GO:0042509 30 0.810
Human
apoptotic mitochondrial changes GO:0008637 57 0.807
regulation of myeloid cell differentiation GO:0045637 81 0.789
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 15 0.788
organic hydroxy compound metabolic process GO:1901615 147 0.787
protein processing GO:0016485 226 0.780
leukocyte apoptotic process GO:0071887 31 0.778
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.776
Zebrafish
regulation of cellular amine metabolic process GO:0033238 11 0.774
apoptotic signaling pathway GO:0097190 268 0.771
release of cytochrome c from mitochondria GO:0001836 35 0.765
i kappab kinase nf kappab signaling GO:0007249 166 0.765
regulation of map kinase activity GO:0043405 108 0.764
amide transport GO:0042886 76 0.764
regulation of release of cytochrome c from mitochondria GO:0090199 29 0.758
tyrosine phosphorylation of stat protein GO:0007260 33 0.736
Human
positive regulation of jak stat cascade GO:0046427 35 0.731
Human
positive regulation of protein phosphorylation GO:0001934 313 0.730
Human
regulation of endothelial cell apoptotic process GO:2000351 24 0.727
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.727
cellular response to external stimulus GO:0071496 111 0.721
cell type specific apoptotic process GO:0097285 125 0.721
positive regulation of programmed cell death GO:0043068 249 0.720
Human Zebrafish
regulation of response to wounding GO:1903034 101 0.715
Human
cellular response to abiotic stimulus GO:0071214 117 0.714
activation of nf kappab inducing kinase activity GO:0007250 9 0.693
regulation of response to external stimulus GO:0032101 222 0.688
Human
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.674
Zebrafish
activation of protein kinase activity GO:0032147 90 0.673
necrotic cell death GO:0070265 21 0.660
Human
necroptotic signaling pathway GO:0097527 6 0.657
Human
negative regulation of cell death GO:0060548 345 0.655
activation of cysteine type endopeptidase activity GO:0097202 57 0.654
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.653
Human
positive regulation of apoptotic signaling pathway GO:2001235 70 0.648
endothelial cell apoptotic process GO:0072577 26 0.634
positive regulation of cell activation GO:0050867 81 0.619
intrinsic apoptotic signaling pathway GO:0097193 127 0.617
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 24 0.605
positive regulation of hydrolase activity GO:0051345 331 0.599
Zebrafish
jak stat cascade GO:0007259 46 0.597
Human
response to endoplasmic reticulum stress GO:0034976 49 0.581
cell fate determination GO:0001709 3 0.578
regulation of inflammatory response GO:0050727 46 0.566
Human
intracellular protein transport GO:0006886 270 0.559
regulation of cell differentiation GO:0045595 393 0.555
positive regulation of mapk cascade GO:0043410 190 0.554
immune system development GO:0002520 195 0.554
positive regulation of protein import into nucleus GO:0042307 46 0.550
cellular response to hyperoxia GO:0071455 4 0.547
Human
cellular response to oxygen levels GO:0071453 55 0.546
Human
positive regulation of bone resorption GO:0045780 2 0.543
response to oxygen levels GO:0070482 100 0.541
Human
regulation of cysteine type endopeptidase activity GO:2000116 127 0.540
Zebrafish
peptidyl tyrosine modification GO:0018212 170 0.539
Human
regulation of peptidase activity GO:0052547 180 0.535
Zebrafish
response to mechanical stimulus GO:0009612 51 0.533
positive regulation of nik nf kappab signaling GO:1901224 10 0.520
negative regulation of apoptotic process GO:0043066 316 0.519
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.502
Human
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 3 0.495
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.489
Human
vasculature development GO:0001944 181 0.487
amine metabolic process GO:0009308 44 0.486
regulation of apoptotic signaling pathway GO:2001233 175 0.484
regulation of myeloid leukocyte differentiation GO:0002761 39 0.474
positive regulation of endothelial cell apoptotic process GO:2000353 8 0.474
regulation of proteolysis GO:0030162 293 0.473
Zebrafish
positive regulation of homeostatic process GO:0032846 47 0.465
positive regulation of leukocyte activation GO:0002696 80 0.459
positive regulation of cell death GO:0010942 263 0.457
Human Zebrafish
response to wounding GO:0009611 168 0.454
Human
negative regulation of synaptic transmission GO:0050805 2 0.450
hematopoietic or lymphoid organ development GO:0048534 186 0.445
maintenance of location GO:0051235 112 0.441
positive regulation of nf kappab import into nucleus GO:0042346 13 0.440
t cell homeostasis GO:0043029 3 0.437
single organism nuclear import GO:1902593 104 0.431
regulation of homeostatic process GO:0032844 121 0.422
positive regulation of intracellular protein transport GO:0090316 76 0.411
positive regulation of immune system process GO:0002684 283 0.404
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.400
regulation of protein processing GO:0070613 150 0.397
positive regulation of myeloid cell differentiation GO:0045639 39 0.393
cellular response to cytokine stimulus GO:0071345 181 0.390
myeloid leukocyte differentiation GO:0002573 60 0.387
hemopoiesis GO:0030097 180 0.385
biological adhesion GO:0022610 331 0.378
regulation of kinase activity GO:0043549 314 0.374
regulation of endopeptidase activity GO:0052548 170 0.373
Zebrafish
single organism cell adhesion GO:0098602 179 0.365
inflammatory response GO:0006954 79 0.363
Human
tyrosine phosphorylation of stat1 protein GO:0042508 11 0.358
Human
cellular response to tumor necrosis factor GO:0071356 63 0.345
response to abiotic stimulus GO:0009628 336 0.343
stress activated protein kinase signaling cascade GO:0031098 94 0.342
regulation of peptide transport GO:0090087 62 0.342
activation induced cell death of t cells GO:0006924 2 0.340
negative regulation of proteolysis GO:0045861 132 0.338
blood vessel development GO:0001568 172 0.324
angiogenesis GO:0001525 147 0.321
regulation of jak stat cascade GO:0046425 44 0.320
Human
regulation of protein targeting GO:1903533 91 0.319
response to organonitrogen compound GO:0010243 156 0.318
negative regulation of intracellular signal transduction GO:1902532 183 0.318
negative regulation of catalytic activity GO:0043086 335 0.316
regulation of osteoclast differentiation GO:0045670 18 0.311
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.309
single organismal cell cell adhesion GO:0016337 148 0.304
positive regulation of map kinase activity GO:0043406 80 0.299
regulation of intracellular transport GO:0032386 195 0.292
positive regulation of t cell activation GO:0050870 54 0.291
cardiovascular system development GO:0072358 262 0.286
engulfment of apoptotic cell GO:0043652 2 0.285
negative regulation of protein processing GO:0010955 142 0.280
establishment of protein localization to organelle GO:0072594 172 0.278
regulation of transcription factor import into nucleus GO:0042990 39 0.275
neural tube formation GO:0001841 3 0.269
pigment metabolic process GO:0042440 16 0.266
regulation of nucleocytoplasmic transport GO:0046822 98 0.259
response to oxygen containing compound GO:1901700 369 0.257
positive regulation of leukocyte differentiation GO:1902107 37 0.250
nucleocytoplasmic transport GO:0006913 176 0.250
response to cytokine GO:0034097 232 0.249
cell cell signaling GO:0007267 155 0.248
positive regulation of protein kinase activity GO:0045860 190 0.239
positive regulation of protein transport GO:0051222 135 0.238
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.235
regulation of cell activation GO:0050865 125 0.234
regulation of erk1 and erk2 cascade GO:0070372 99 0.233
positive regulation of cellular amine metabolic process GO:0033240 7 0.232
regulation of protein maturation GO:1903317 150 0.228
positive regulation of transferase activity GO:0051347 227 0.227
negative regulation of t cell apoptotic process GO:0070233 4 0.225
lymphocyte homeostasis GO:0002260 4 0.222
cytoplasmic sequestering of nf kappab GO:0007253 7 0.219
cell activation GO:0001775 213 0.219
regulation of leukocyte differentiation GO:1902105 61 0.218
positive regulation of cell differentiation GO:0045597 211 0.212
regulation of protein import into nucleus GO:0042306 78 0.211
positive regulation of cell motility GO:2000147 177 0.210
anatomical structure homeostasis GO:0060249 100 0.210
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 22 0.207
positive regulation of protein localization to nucleus GO:1900182 48 0.207
epithelial cell differentiation GO:0030855 141 0.203
cellular response to dna damage stimulus GO:0006974 379 0.201
protein maturation GO:0051604 233 0.201
positive regulation of peptidase activity GO:0010952 88 0.201
Zebrafish
negative regulation of intracellular protein transport GO:0090317 42 0.199
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.199
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.196
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.196
regulation of lymphocyte activation GO:0051249 103 0.193
chemotaxis GO:0006935 157 0.191
regulation of t cell activation GO:0050863 77 0.188
positive regulation of cell proliferation GO:0008284 301 0.187
leukocyte chemotaxis GO:0030595 76 0.187
response to biotic stimulus GO:0009607 276 0.185
positive regulation of transport GO:0051050 336 0.183
regulation of establishment of protein localization GO:0070201 242 0.182
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.182
defense response to bacterium GO:0042742 63 0.177
signal transduction by phosphorylation GO:0023014 297 0.175
regulation of angiogenesis GO:0045765 92 0.173
regulation of mapk cascade GO:0043408 262 0.170
regulation of cell adhesion GO:0030155 166 0.169
negative regulation of vasculature development GO:1901343 43 0.169
positive regulation of cell migration GO:0030335 172 0.165
negative regulation of apoptotic signaling pathway GO:2001234 97 0.165
regulation of cellular response to stress GO:0080135 244 0.163
positive regulation of t cell migration GO:2000406 13 0.161
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.159
regulation of leukocyte migration GO:0002685 63 0.157
negative regulation of transport GO:0051051 176 0.155
negative regulation of hydrolase activity GO:0051346 182 0.153
positive regulation of endopeptidase activity GO:0010950 84 0.153
Zebrafish
development of primary male sexual characteristics GO:0046546 23 0.151
synaptic transmission GO:0007268 61 0.150
nitrogen compound transport GO:0071705 191 0.143
response to external biotic stimulus GO:0043207 261 0.142
macrophage differentiation GO:0030225 11 0.141
spleen development GO:0048536 1 0.137
regulation of bone resorption GO:0045124 4 0.136
positive regulation of developmental process GO:0051094 314 0.135
response to insulin GO:0032868 45 0.134
cytoplasmic transport GO:0016482 379 0.134
regulation of vasculature development GO:1901342 97 0.134
mitotic cell cycle GO:0000278 326 0.133
negative regulation of protein metabolic process GO:0051248 391 0.132
nik nf kappab signaling GO:0038061 12 0.131
maintenance of protein location in cell GO:0032507 56 0.131
morphogenesis of embryonic epithelium GO:0016331 4 0.130
negative regulation of lymphocyte apoptotic process GO:0070229 8 0.128
positive regulation of tyrosine phosphorylation of stat1 protein GO:0042511 8 0.125
Human
single organism cellular localization GO:1902580 332 0.124
cytokine metabolic process GO:0042107 38 0.122
response to peptide GO:1901652 65 0.118
regulation of cell cycle arrest GO:0071156 36 0.118
tissue homeostasis GO:0001894 63 0.117
defense response GO:0006952 315 0.114
Human
positive regulation of intracellular transport GO:0032388 104 0.114
regulation of macrophage differentiation GO:0045649 9 0.113
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.111
regeneration GO:0031099 4 0.111
regulation of cell motility GO:2000145 299 0.109
response to other organism GO:0051707 261 0.108
anatomical structure formation involved in morphogenesis GO:0048646 284 0.107
cellular ketone metabolic process GO:0042180 80 0.107
thymocyte apoptotic process GO:0070242 2 0.106
positive regulation of transcription factor import into nucleus GO:0042993 25 0.102
tissue regeneration GO:0042246 3 0.101
tnfsf11 mediated signaling pathway GO:0071847 2 0.100
epithelium development GO:0060429 227 0.098
positive regulation of cellular extravasation GO:0002693 3 0.097
negative regulation of i kappab kinase nf kappab signaling GO:0043124 32 0.096
regulation of cell cycle process GO:0010564 266 0.093
positive regulation of adaptive immune response GO:0002821 21 0.093
negative regulation of protein maturation GO:1903318 142 0.093
negative regulation of peptidase activity GO:0010466 91 0.091
negative regulation of necrotic cell death GO:0060547 3 0.089
negative regulation of intracellular transport GO:0032387 60 0.087
myeloid leukocyte migration GO:0097529 62 0.087
response to organic cyclic compound GO:0014070 204 0.087
ubiquitin dependent protein catabolic process GO:0006511 206 0.086
cellular amine metabolic process GO:0044106 41 0.086
single organism reproductive process GO:0044702 98 0.085
response to water GO:0009415 2 0.084
cellular protein catabolic process GO:0044257 261 0.083
blood vessel morphogenesis GO:0048514 162 0.082
lymphocyte proliferation GO:0046651 70 0.082
regulation of lymphocyte apoptotic process GO:0070228 15 0.081
tissue morphogenesis GO:0048729 96 0.081
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.081
mitotic cell cycle process GO:1903047 286 0.080
skeletal muscle tissue regeneration GO:0043403 2 0.080
negative regulation of multicellular organismal process GO:0051241 317 0.080
t cell activation GO:0042110 99 0.080
response to lipid GO:0033993 206 0.079
regulation of protein kinase activity GO:0045859 289 0.078
regulation of protein serine threonine kinase activity GO:0071900 179 0.078
negative regulation of protein import into nucleus GO:0042308 30 0.078
homotypic cell cell adhesion GO:0034109 47 0.077
leukocyte differentiation GO:0002521 98 0.077
regulation of necroptotic process GO:0060544 7 0.077
regulation of innate immune response GO:0045088 97 0.077
positive regulation of osteoclast differentiation GO:0045672 9 0.075
regulation of myotube differentiation GO:0010830 18 0.074
carbohydrate metabolic process GO:0005975 207 0.074
ion transmembrane transport GO:0034220 338 0.072
membrane organization GO:0061024 292 0.072
positive regulation of cellular component organization GO:0051130 376 0.071
apoptotic cell clearance GO:0043277 12 0.071
negative regulation of transcription factor import into nucleus GO:0042992 17 0.070
response to decreased oxygen levels GO:0036293 96 0.068
negative regulation of developmental process GO:0051093 247 0.067
regulation of mitochondrion organization GO:0010821 54 0.067
cytokine mediated signaling pathway GO:0019221 109 0.067
negative regulation of homeostatic process GO:0032845 59 0.067
execution phase of apoptosis GO:0097194 32 0.065
striated muscle cell proliferation GO:0014855 7 0.064
response to uv GO:0009411 73 0.064
regulation of myoblast fusion GO:1901739 1 0.064
negative regulation of protein localization to nucleus GO:1900181 34 0.063
regulation of leukocyte proliferation GO:0070663 67 0.061
negative regulation of nf kappab import into nucleus GO:0042347 12 0.061
regulation of intracellular protein transport GO:0033157 123 0.060
t cell differentiation in thymus GO:0033077 4 0.059
regulation of response to dna damage stimulus GO:2001020 94 0.058
negative regulation of cytoplasmic transport GO:1903650 46 0.058
signal transduction in absence of ligand GO:0038034 22 0.057
negative regulation of endopeptidase activity GO:0010951 84 0.057
positive regulation of tumor necrosis factor production GO:0032760 21 0.056
peptidyl tyrosine phosphorylation GO:0018108 170 0.056
Human
negative regulation of protein transport GO:0051224 75 0.056
skeletal myofibril assembly GO:0014866 3 0.056
negative regulation of phosphate metabolic process GO:0045936 267 0.056
protein homooligomerization GO:0051260 100 0.055
mitotic dna damage checkpoint GO:0044773 28 0.054
regulation of anatomical structure morphogenesis GO:0022603 286 0.054
epithelial tube morphogenesis GO:0060562 38 0.053
negative regulation of inflammatory response GO:0050728 22 0.053
Human
positive regulation of cellular component movement GO:0051272 181 0.053
cell chemotaxis GO:0060326 112 0.052
morphogenesis of an epithelium GO:0002009 60 0.052
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.052
regulation of transferase activity GO:0051338 355 0.052
female gamete generation GO:0007292 2 0.052
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.051
post embryonic development GO:0009791 2 0.051
regulation of mononuclear cell proliferation GO:0032944 65 0.051
cellular response to lipid GO:0071396 127 0.051
mitotic cell cycle checkpoint GO:0007093 68 0.051
regulation of reactive oxygen species metabolic process GO:2000377 41 0.050
nf kappab import into nucleus GO:0042348 22 0.049
response to bacterium GO:0009617 144 0.049
regulation of leukocyte activation GO:0002694 115 0.049
taxis GO:0042330 157 0.049
defense response to other organism GO:0098542 129 0.049
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.047
carbohydrate derivative biosynthetic process GO:1901137 207 0.047
single organism carbohydrate metabolic process GO:0044723 193 0.047
regulation of tissue remodeling GO:0034103 9 0.046
tumor necrosis factor mediated signaling pathway GO:0033209 27 0.046
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.046
positive regulation of locomotion GO:0040017 186 0.046
embryo development GO:0009790 123 0.046
leukocyte activation GO:0045321 164 0.046
transcription factor import into nucleus GO:0042991 40 0.045
protein targeting GO:0006605 187 0.045
response to estrogen GO:0043627 47 0.043
response to virus GO:0009615 126 0.043
cellular homeostasis GO:0019725 196 0.043
regulation of cell cell adhesion GO:0022407 57 0.042
stress activated mapk cascade GO:0051403 93 0.042
maintenance of protein location GO:0045185 57 0.041
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001241 4 0.041
regulation of leukocyte apoptotic process GO:2000106 25 0.040
negative regulation of mitotic cell cycle GO:0045930 102 0.040
myoblast fusion GO:0007520 1 0.040
cell adhesion GO:0007155 325 0.040
cell development GO:0048468 328 0.040
inflammatory cell apoptotic process GO:0006925 3 0.040
neuron cellular homeostasis GO:0070050 3 0.040
cellular response to endogenous stimulus GO:0071495 336 0.039
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 22 0.039
mapk cascade GO:0000165 288 0.039
lymphocyte mediated immunity GO:0002449 48 0.039
regulation of cell cycle GO:0051726 393 0.039
protein complex localization GO:0031503 31 0.037
response to nitrogen compound GO:1901698 184 0.037
activated t cell proliferation GO:0050798 13 0.037
protein import GO:0017038 130 0.036
negative regulation of cellular protein metabolic process GO:0032269 353 0.035
vascular wound healing GO:0061042 4 0.035
cell cycle arrest GO:0007050 71 0.035
regulation of protein complex assembly GO:0043254 147 0.035
cellular response to hypoxia GO:0071456 51 0.034
response to alcohol GO:0097305 64 0.034
reproductive process GO:0022414 106 0.034
cell projection organization GO:0030030 252 0.033
adaptive immune response GO:0002250 49 0.033
regulation of bone remodeling GO:0046850 6 0.033
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.033
cellular macromolecule catabolic process GO:0044265 380 0.033
cytoplasmic sequestering of transcription factor GO:0042994 9 0.033
negative regulation of leukocyte apoptotic process GO:2000107 16 0.033
gland development GO:0048732 48 0.033
positive regulation of t cell proliferation GO:0042102 33 0.032
interleukin 8 production GO:0032637 51 0.032
muscle structure development GO:0061061 98 0.032
positive regulation of kinase activity GO:0033674 204 0.032
cellular response to organonitrogen compound GO:0071417 124 0.032
regulation of cell migration GO:0030334 289 0.032
response to radiation GO:0009314 151 0.031
positive regulation of lymphocyte activation GO:0051251 73 0.031
innate immune response GO:0045087 178 0.031
protein oligomerization GO:0051259 173 0.031
thymus development GO:0048538 3 0.031
response to carbohydrate GO:0009743 21 0.031
mitochondrion organization GO:0007005 156 0.030
regulation of t cell mediated immunity GO:0002709 18 0.030
melanin metabolic process GO:0006582 1 0.030
nervous system development GO:0007399 293 0.030
regulation of protein transport GO:0051223 213 0.030
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.030
tube morphogenesis GO:0035239 95 0.029
positive regulation of cell adhesion GO:0045785 84 0.029
striated muscle adaptation GO:0014888 4 0.029
positive regulation of organelle organization GO:0010638 195 0.028
response to drug GO:0042493 81 0.028
determination of adult lifespan GO:0008340 2 0.028
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 20 0.028
neuron projection regeneration GO:0031102 1 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.027
regulation of homotypic cell cell adhesion GO:0034110 8 0.027
lymphocyte activation GO:0046649 133 0.027
regulation of activated t cell proliferation GO:0046006 12 0.027
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.026
growth GO:0040007 202 0.026
regulation of cell cycle phase transition GO:1901987 126 0.026
regulation of locomotion GO:0040012 329 0.026
cytokine production GO:0001816 247 0.026
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.026
regulation of protein localization GO:0032880 296 0.026
negative regulation of myotube differentiation GO:0010832 4 0.026
immune response GO:0006955 307 0.026
striated muscle cell differentiation GO:0051146 43 0.025
proteasomal protein catabolic process GO:0010498 176 0.025
oocyte differentiation GO:0009994 2 0.025
actomyosin structure organization GO:0031032 59 0.025
neuron apoptotic process GO:0051402 39 0.024
response to hypoxia GO:0001666 96 0.024
oogenesis GO:0048477 2 0.024
signal transduction in response to dna damage GO:0042770 57 0.024
establishment of protein localization to membrane GO:0090150 121 0.024
negative regulation of phosphorus metabolic process GO:0010563 267 0.024
regulation of axon guidance GO:1902667 3 0.024
response to hormone GO:0009725 175 0.023
cellular response to radiation GO:0071478 65 0.023
leukocyte proliferation GO:0070661 74 0.023
regulation of t cell apoptotic process GO:0070232 8 0.023
dna damage checkpoint GO:0000077 68 0.023
response to lipopolysaccharide GO:0032496 70 0.023
neuron death GO:0070997 65 0.023
toll like receptor 2 signaling pathway GO:0034134 4 0.023
transmembrane transport GO:0055085 399 0.023
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.023
regulation of meiotic cell cycle GO:0051445 4 0.022
negative regulation of response to external stimulus GO:0032102 83 0.022
Human
negative regulation of cell cycle phase transition GO:1901988 89 0.022
negative regulation of cellular component organization GO:0051129 235 0.022
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:0042771 23 0.022
positive regulation of cell cell adhesion GO:0022409 22 0.022
t cell differentiation GO:0030217 29 0.022
branching morphogenesis of an epithelial tube GO:0048754 19 0.022
lipid metabolic process GO:0006629 381 0.022
wnt signaling pathway GO:0016055 156 0.022
circadian behavior GO:0048512 2 0.022
negative regulation of cell differentiation GO:0045596 171 0.022
muscle system process GO:0003012 81 0.021
negative regulation of defense response GO:0031348 47 0.021
Human
positive regulation of tissue remodeling GO:0034105 4 0.021
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.021
regulation of lymphocyte proliferation GO:0050670 64 0.021
skeletal muscle cell proliferation GO:0014856 1 0.021
positive regulation of cytoplasmic transport GO:1903651 82 0.021
reproductive structure development GO:0048608 55 0.021
dna repair GO:0006281 198 0.021
memory GO:0007613 3 0.021
oxidation reduction process GO:0055114 396 0.021
regulation of cell cycle g1 s phase transition GO:1902806 42 0.021
negative regulation of blood vessel morphogenesis GO:2000181 41 0.020
regulation of cell growth GO:0001558 135 0.020
system process GO:0003008 349 0.020
brain development GO:0007420 97 0.020
interspecies interaction between organisms GO:0044419 156 0.020
negative regulation of endothelial cell apoptotic process GO:2000352 16 0.020
regulation of cellular component movement GO:0051270 334 0.020
head development GO:0060322 108 0.020
cellular chemical homeostasis GO:0055082 180 0.020
reactive nitrogen species metabolic process GO:2001057 3 0.020
cellular response to decreased oxygen levels GO:0036294 51 0.020
regulation of leukocyte mediated immunity GO:0002703 38 0.020
patterning of blood vessels GO:0001569 2 0.020
regulation of protein secretion GO:0050708 86 0.020
rhythmic behavior GO:0007622 2 0.020
cellular response to oxygen containing compound GO:1901701 276 0.020
multicellular organismal aging GO:0010259 3 0.020
multicellular organismal homeostasis GO:0048871 67 0.020

TNFRSF10B disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.286
Human
gastrointestinal system cancer DOID:3119 52 0.109
hepatocellular carcinoma DOID:684 9 0.109
liver carcinoma DOID:686 9 0.109
cancer DOID:162 167 0.109
disease of cellular proliferation DOID:14566 174 0.109
organ system cancer DOID:0050686 164 0.109
liver cancer DOID:3571 9 0.109
sensory system disease DOID:0050155 203 0.051
eye and adnexa disease DOID:1492 150 0.051
nervous system disease DOID:863 431 0.051
Human
disease of metabolism DOID:0014667 295 0.051
eye disease DOID:5614 149 0.023
musculoskeletal system disease DOID:17 223 0.020
connective tissue disease DOID:65 109 0.020
inherited metabolic disorder DOID:655 242 0.019