Homo sapiens

48 known processes

TOMM22

translocase of outer mitochondrial membrane 22 homolog (yeast)

(Aliases: MSTP065,MST065,1C9-2,TOM22)

TOMM22 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein targeting to mitochondrion GO:0006626 19 0.418
protein localization to mitochondrion GO:0070585 25 0.388
intracellular protein transport GO:0006886 270 0.345
mitochondrion organization GO:0007005 156 0.330
post embryonic development GO:0009791 2 0.312
Worm
cytoplasmic transport GO:0016482 379 0.294
transmembrane transport GO:0055085 399 0.228
mitochondrial membrane organization GO:0007006 40 0.124
determination of adult lifespan GO:0008340 2 0.109
single organism membrane organization GO:0044802 268 0.103
establishment of protein localization to mitochondrion GO:0072655 22 0.098
mitochondrial transport GO:0006839 60 0.095
intracellular protein transmembrane transport GO:0065002 24 0.089
cellular macromolecular complex assembly GO:0034622 324 0.088
protein localization to organelle GO:0033365 280 0.084
protein secretion GO:0009306 98 0.079
Worm
membrane organization GO:0061024 292 0.077
multicellular organismal aging GO:0010259 3 0.075
cation transport GO:0006812 331 0.070
embryo development GO:0009790 123 0.068
Worm
establishment of rna localization GO:0051236 39 0.068
single organism cellular localization GO:1902580 332 0.068
amine metabolic process GO:0009308 44 0.066
protein targeting GO:0006605 187 0.061
myosin filament organization GO:0031033 2 0.058
lipid metabolic process GO:0006629 381 0.057
cellular lipid metabolic process GO:0044255 303 0.057
ion transmembrane transport GO:0034220 338 0.052
regulation of oxidative phosphorylation GO:0002082 3 0.050
regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108 18 0.049
cellular component morphogenesis GO:0032989 314 0.048
rna transport GO:0050658 39 0.048
positive regulation of growth GO:0045927 58 0.048
female gamete generation GO:0007292 2 0.047
lipid localization GO:0010876 106 0.046
nucleocytoplasmic transport GO:0006913 176 0.046
dna catabolic process GO:0006308 49 0.043
positive regulation of immune system process GO:0002684 283 0.043
oogenesis GO:0048477 2 0.043
generation of precursor metabolites and energy GO:0006091 68 0.042
positive regulation of cellular component organization GO:0051130 376 0.042
secretion GO:0046903 254 0.040
Worm
metal ion transport GO:0030001 272 0.037
secretion by cell GO:0032940 226 0.037
Worm
nitrogen compound transport GO:0071705 191 0.036
response to abiotic stimulus GO:0009628 336 0.036
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.035
cellular metal ion homeostasis GO:0006875 146 0.034
cellular homeostasis GO:0019725 196 0.034
regulation of cellular amine metabolic process GO:0033238 11 0.033
endocytosis GO:0006897 159 0.033
Worm
immune response regulating signaling pathway GO:0002764 97 0.033
nuclear export GO:0051168 69 0.032
myosin filament assembly GO:0031034 2 0.032
regulation of feeding behavior GO:0060259 3 0.031
mrna processing GO:0006397 133 0.031
maintenance of location GO:0051235 112 0.031
regulation of mitochondrion organization GO:0010821 54 0.030
negative regulation of cellular component organization GO:0051129 235 0.030
locomotory behavior GO:0007626 1 0.029
adult locomotory behavior GO:0008344 1 0.029
establishment of protein localization to organelle GO:0072594 172 0.029
apoptotic signaling pathway GO:0097190 268 0.029
positive regulation of apoptotic process GO:0043065 246 0.029
rna export from nucleus GO:0006405 33 0.028
regulation of transporter activity GO:0032409 82 0.028
immune response GO:0006955 307 0.028
vesicle mediated transport GO:0016192 371 0.028
Worm
defense response GO:0006952 315 0.027
posttranscriptional regulation of gene expression GO:0010608 213 0.027
small molecule biosynthetic process GO:0044283 157 0.027
positive regulation of organelle organization GO:0010638 195 0.026
response to oxygen levels GO:0070482 100 0.026
regulation of growth GO:0040008 165 0.026
cellular macromolecule catabolic process GO:0044265 380 0.026
actin filament based process GO:0030029 224 0.025
cellular ketone metabolic process GO:0042180 80 0.025
receptor mediated endocytosis GO:0006898 84 0.025
Worm
glycerolipid metabolic process GO:0046486 107 0.025
regulation of ion transport GO:0043269 189 0.025
positive regulation of mitochondrion organization GO:0010822 30 0.024
negative regulation of apoptotic process GO:0043066 316 0.024
reproduction GO:0000003 63 0.024
regulation of anatomical structure morphogenesis GO:0022603 286 0.024
nuclear transport GO:0051169 179 0.023
protein localization to membrane GO:0072657 160 0.023
positive regulation of cell death GO:0010942 263 0.023
regulation of purine nucleotide metabolic process GO:1900542 264 0.022
multi organism cellular process GO:0044764 156 0.022
regulation of nucleoside metabolic process GO:0009118 209 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.021
rna processing GO:0006396 255 0.021
rna interference GO:0016246 4 0.021
growth GO:0040007 202 0.021
organelle assembly GO:0070925 176 0.021
response to hypoxia GO:0001666 96 0.021
protein k11 linked ubiquitination GO:0070979 24 0.021
translation GO:0006412 132 0.021
antigen receptor mediated signaling pathway GO:0050851 38 0.021
spermatid differentiation GO:0048515 4 0.020
reproductive process GO:0022414 106 0.020
cell morphogenesis GO:0000902 296 0.020
negative regulation of programmed cell death GO:0043069 321 0.020
reproductive system development GO:0061458 56 0.020
epithelium development GO:0060429 227 0.020
regulation of cellular component biogenesis GO:0044087 281 0.020
cardiovascular system development GO:0072358 262 0.020
regeneration GO:0031099 4 0.020
chemical homeostasis GO:0048878 306 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
sensory perception GO:0007600 103 0.019
response to cytokine GO:0034097 232 0.018
cellular response to dna damage stimulus GO:0006974 379 0.018
positive regulation of developmental process GO:0051094 314 0.018
response to axon injury GO:0048678 1 0.018
response to virus GO:0009615 126 0.018
cell part morphogenesis GO:0032990 137 0.018
segmentation GO:0035282 4 0.018
protein maturation GO:0051604 233 0.018
positive regulation of trophoblast cell migration GO:1901165 2 0.018
biological adhesion GO:0022610 331 0.018
intracellular protein transmembrane import GO:0044743 23 0.018
regulation of nucleotide metabolic process GO:0006140 269 0.017
peptidyl serine modification GO:0018209 106 0.017
negative regulation of organelle organization GO:0010639 126 0.017
phospholipid metabolic process GO:0006644 99 0.017
cation transmembrane transport GO:0098655 238 0.017
morphogenesis of an epithelium GO:0002009 60 0.017
cellular chemical homeostasis GO:0055082 180 0.017
mrna export from nucleus GO:0006406 29 0.017
cellular protein catabolic process GO:0044257 261 0.017
developmental process involved in reproduction GO:0003006 66 0.016
positive regulation of immune response GO:0050778 159 0.016
negative regulation of nucleotide metabolic process GO:0045980 29 0.016
ribosomal subunit export from nucleus GO:0000054 4 0.016
regulation of lipid metabolic process GO:0019216 96 0.016
establishment of protein localization to membrane GO:0090150 121 0.016
mrna transport GO:0051028 30 0.016
activation of immune response GO:0002253 114 0.016
cell growth GO:0016049 160 0.016
system process GO:0003008 349 0.016
regulation of peptidase activity GO:0052547 180 0.016
mitotic cell cycle process GO:1903047 286 0.016
cell development GO:0048468 328 0.016
response to other organism GO:0051707 261 0.016
cellular amine metabolic process GO:0044106 41 0.015
negative regulation of apoptotic signaling pathway GO:2001234 97 0.015
cell adhesion GO:0007155 325 0.015
positive regulation of programmed cell death GO:0043068 249 0.015
organelle localization GO:0051640 84 0.015
divalent metal ion transport GO:0070838 152 0.015
cellular response to oxygen containing compound GO:1901701 276 0.015
regulation of immune response GO:0050776 201 0.015
divalent inorganic cation transport GO:0072511 158 0.015
cellular protein complex assembly GO:0043623 188 0.015
regulation of cellular amino acid metabolic process GO:0006521 6 0.014
nucleoside triphosphate catabolic process GO:0009143 394 0.014
nuclear migration GO:0007097 1 0.014
cellular amino acid metabolic process GO:0006520 116 0.014
immune response activating signal transduction GO:0002757 90 0.014
regulation of mitochondrial membrane permeability GO:0046902 25 0.014
regulation of cell cycle process GO:0010564 266 0.014
rna splicing via transesterification reactions GO:0000375 90 0.014
protein processing GO:0016485 226 0.014
regulation of mitochondrial membrane potential GO:0051881 23 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.014
angiogenesis GO:0001525 147 0.013
protein ubiquitination GO:0016567 314 0.013
small gtpase mediated signal transduction GO:0007264 78 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.013
regulation of cellular ketone metabolic process GO:0010565 50 0.013
purine ribonucleoside metabolic process GO:0046128 437 0.013
anterior posterior axis specification GO:0009948 2 0.013
regulation of cell differentiation GO:0045595 393 0.013
response to biotic stimulus GO:0009607 276 0.013
cell division GO:0051301 168 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
taxis GO:0042330 157 0.013
intracellular receptor signaling pathway GO:0030522 104 0.013
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.013
metal ion homeostasis GO:0055065 169 0.013
cellular ion homeostasis GO:0006873 168 0.013
anion transport GO:0006820 161 0.012
cellular component assembly involved in morphogenesis GO:0010927 73 0.012
protein transmembrane transport GO:0071806 25 0.012
cation homeostasis GO:0055080 189 0.012
cellular divalent inorganic cation homeostasis GO:0072503 128 0.012
nucleic acid transport GO:0050657 39 0.012
purine nucleoside triphosphate metabolic process GO:0009144 412 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
neuron projection development GO:0031175 106 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.012
regulation of cell projection organization GO:0031344 107 0.012
positive regulation of cell cycle GO:0045787 140 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
response to hormone GO:0009725 175 0.012
glycerophospholipid metabolic process GO:0006650 84 0.012
behavior GO:0007610 112 0.012
lipid storage GO:0019915 28 0.012
nervous system development GO:0007399 293 0.012
engulfment of apoptotic cell GO:0043652 2 0.011
ribonucleoprotein complex export from nucleus GO:0071426 4 0.011
regulation of gene expression epigenetic GO:0040029 73 0.011
calcium ion transport GO:0006816 147 0.011
muscle structure development GO:0061061 98 0.011
negative regulation of catalytic activity GO:0043086 335 0.011
single organism membrane fusion GO:0044801 37 0.011
establishment of organelle localization GO:0051656 59 0.011
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.011
blastoderm segmentation GO:0007350 2 0.011
neuromuscular junction development GO:0007528 3 0.011
positive regulation of peptidase activity GO:0010952 88 0.011
negative regulation of catabolic process GO:0009895 104 0.011
response to external biotic stimulus GO:0043207 261 0.011
purine containing compound catabolic process GO:0072523 411 0.011
response to drug GO:0042493 81 0.011
covalent chromatin modification GO:0016569 254 0.010
nucleoside triphosphate metabolic process GO:0009141 422 0.010
detection of stimulus GO:0051606 85 0.010
nucleobase containing compound transport GO:0015931 51 0.010
single organism reproductive process GO:0044702 98 0.010
response to decreased oxygen levels GO:0036293 96 0.010
regulation of cell development GO:0060284 161 0.010
response to oxidative stress GO:0006979 121 0.010
leukocyte migration GO:0050900 107 0.010
regulation of behavior GO:0050795 82 0.010
regulation of cell adhesion GO:0030155 166 0.010

TOMM22 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.034
disease of cellular proliferation DOID:14566 174 0.034
organ system cancer DOID:0050686 164 0.034
sensory system disease DOID:0050155 203 0.024
eye and adnexa disease DOID:1492 150 0.024
nervous system disease DOID:863 431 0.024
retinal disease DOID:5679 118 0.010
retinal degeneration DOID:8466 89 0.010
eye disease DOID:5614 149 0.010