Homo sapiens

217 known processes

TOR1A

torsin family 1, member A (torsin A)

(Aliases: DYT1,DQ2)

TOR1A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
endoplasmic reticulum organization GO:0007029 20 1.000
Human
ribonucleoside monophosphate catabolic process GO:0009158 158 0.998
nucleoside monophosphate catabolic process GO:0009125 159 0.994
atp catabolic process GO:0006200 157 0.991
purine nucleoside monophosphate catabolic process GO:0009128 158 0.986
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.985
ribonucleoside monophosphate metabolic process GO:0009161 187 0.981
nucleoside catabolic process GO:0009164 408 0.979
nucleoside monophosphate metabolic process GO:0009123 191 0.949
purine nucleoside monophosphate metabolic process GO:0009126 186 0.946
ribonucleoside catabolic process GO:0042454 406 0.945
purine nucleotide catabolic process GO:0006195 405 0.932
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.920
nucleoside triphosphate catabolic process GO:0009143 394 0.910
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.906
purine ribonucleotide catabolic process GO:0009154 404 0.902
purine nucleoside triphosphate catabolic process GO:0009146 392 0.901
purine containing compound catabolic process GO:0072523 411 0.899
regulation of atpase activity GO:0043462 25 0.890
nucleotide catabolic process GO:0009166 408 0.882
positive regulation of synaptic vesicle transport GO:1902805 1 0.877
ribonucleoside triphosphate metabolic process GO:0009199 412 0.854
regulation of atp metabolic process GO:1903578 29 0.850
ribonucleotide catabolic process GO:0009261 405 0.833
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.805
regulation of synaptic transmission dopaminergic GO:0032225 4 0.799
purine nucleoside catabolic process GO:0006152 398 0.746
atp metabolic process GO:0046034 176 0.702
ribonucleoside triphosphate catabolic process GO:0009203 391 0.686
regulation of atp catabolic process GO:1903289 25 0.667
positive regulation of synaptic vesicle endocytosis GO:1900244 1 0.610
nucleoside phosphate catabolic process GO:1901292 412 0.597
regulation of dopamine uptake involved in synaptic transmission GO:0051584 4 0.581
dopamine transport GO:0015872 5 0.460
positive regulation of atpase activity GO:0032781 19 0.458
regulation of amine transport GO:0051952 5 0.458
dopamine uptake involved in synaptic transmission GO:0051583 4 0.448
glycosyl compound catabolic process GO:1901658 413 0.439
regulation of purine nucleotide catabolic process GO:0033121 205 0.405
organophosphate catabolic process GO:0046434 430 0.404
positive regulation of nucleotide catabolic process GO:0030813 185 0.383
regulation of nucleotide catabolic process GO:0030811 205 0.381
regulation of nucleotide metabolic process GO:0006140 269 0.366
synaptic vesicle recycling GO:0036465 3 0.361
regulation of synaptic vesicle transport GO:1902803 3 0.334
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.331
purine ribonucleoside catabolic process GO:0046130 398 0.320
purine ribonucleoside metabolic process GO:0046128 437 0.308
nuclear membrane organization GO:0071763 1 0.308
protein localization to organelle GO:0033365 280 0.303
positive regulation of nucleoside metabolic process GO:0045979 186 0.299
purine nucleoside triphosphate metabolic process GO:0009144 412 0.296
positive regulation of synaptic vesicle recycling GO:1903423 1 0.270
positive regulation of nucleotide metabolic process GO:0045981 230 0.257
regulation of nucleoside metabolic process GO:0009118 209 0.246
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.246
positive regulation of hydrolase activity GO:0051345 331 0.244
positive regulation of catabolic process GO:0009896 310 0.217
cation transport GO:0006812 331 0.208
regulation of purine nucleotide metabolic process GO:1900542 264 0.189
regulation of neurotransmitter uptake GO:0051580 4 0.185
intermediate filament cytoskeleton organization GO:0045104 17 0.184
negative regulation of protein processing GO:0010955 142 0.182
regulation of protein localization GO:0032880 296 0.177
regulation of synaptic vesicle endocytosis GO:1900242 1 0.167
negative regulation of protein maturation GO:1903318 142 0.164
cell cell signaling GO:0007267 155 0.162
protein modification by small protein removal GO:0070646 92 0.154
positive regulation of cellular catabolic process GO:0031331 284 0.145
intermediate filament based process GO:0045103 17 0.138
protein processing GO:0016485 226 0.138
vesicle mediated transport GO:0016192 371 0.137
dopamine uptake GO:0090494 4 0.136
catecholamine uptake involved in synaptic transmission GO:0051934 4 0.133
protein folding GO:0006457 38 0.133
protein homooligomerization GO:0051260 100 0.132
negative regulation of catabolic process GO:0009895 104 0.126
synaptic vesicle transport GO:0048489 5 0.122
endomembrane system organization GO:0010256 196 0.120
Human
post embryonic development GO:0009791 2 0.117
positive regulation of cellular component organization GO:0051130 376 0.110
negative regulation of cellular protein metabolic process GO:0032269 353 0.109
membrane organization GO:0061024 292 0.108
cell adhesion GO:0007155 325 0.097
single organism membrane organization GO:0044802 268 0.092
organelle localization GO:0051640 84 0.091
establishment of vesicle localization GO:0051650 23 0.090
positive regulation of atp catabolic process GO:1903291 19 0.090
positive regulation of transport GO:0051050 336 0.086
negative regulation of proteolysis GO:0045861 132 0.086
neurotransmitter transport GO:0006836 10 0.082
mitotic cell cycle GO:0000278 326 0.078
negative regulation of protein metabolic process GO:0051248 391 0.075
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.074
proteasomal protein catabolic process GO:0010498 176 0.074
positive regulation of endocytosis GO:0045807 42 0.073
modification dependent protein catabolic process GO:0019941 209 0.070
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.070
protein oligomerization GO:0051259 173 0.070
regulation of ion transport GO:0043269 189 0.067
protein deneddylation GO:0000338 10 0.065
organic hydroxy compound transport GO:0015850 63 0.063
negative regulation of cellular catabolic process GO:0031330 83 0.061
vesicle localization GO:0051648 26 0.060
endocytosis GO:0006897 159 0.059
cellular response to dna damage stimulus GO:0006974 379 0.058
modification dependent macromolecule catabolic process GO:0043632 212 0.055
synaptic transmission dopaminergic GO:0001963 5 0.055
cellular macromolecule catabolic process GO:0044265 380 0.050
regulation of protein catabolic process GO:0042176 155 0.049
protein localization to cell surface GO:0034394 28 0.049
protein maturation GO:0051604 233 0.047
protein localization to nucleus GO:0034504 136 0.047
nucleoside triphosphate metabolic process GO:0009141 422 0.047
regulation of cell cycle GO:0051726 393 0.045
amine transport GO:0015837 7 0.044
chaperone mediated protein folding GO:0061077 13 0.043
negative regulation of cellular protein catabolic process GO:1903363 38 0.043
neuron projection development GO:0031175 106 0.041
synaptic vesicle localization GO:0097479 5 0.039
protein catabolic process GO:0030163 325 0.039
cell division GO:0051301 168 0.039
regulation of endocytosis GO:0030100 72 0.037
chaperone mediated protein transport GO:0072321 5 0.037
lipid metabolic process GO:0006629 381 0.036
cell cycle checkpoint GO:0000075 117 0.036
mitotic cell cycle process GO:1903047 286 0.036
cell cycle phase transition GO:0044770 173 0.034
cellular lipid metabolic process GO:0044255 303 0.033
regulation of cell cycle phase transition GO:1901987 126 0.033
neuron neuron synaptic transmission GO:0007270 6 0.033
dna damage checkpoint GO:0000077 68 0.033
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.032
regulation of protein stability GO:0031647 87 0.031
locomotory behavior GO:0007626 1 0.031
regulation of protein processing GO:0070613 150 0.031
determination of adult lifespan GO:0008340 2 0.031
multicellular organismal aging GO:0010259 3 0.030
oogenesis GO:0048477 2 0.030
carbohydrate metabolic process GO:0005975 207 0.030
regulation of protein localization to cell surface GO:2000008 15 0.029
regulation of proteolysis GO:0030162 293 0.029
regulation of protein maturation GO:1903317 150 0.029
neuron differentiation GO:0030182 138 0.027
small molecule biosynthetic process GO:0044283 157 0.027
regulation of cell cycle process GO:0010564 266 0.027
negative regulation of cell cycle GO:0045786 193 0.027
intracellular protein transport GO:0006886 270 0.026
ubiquitin dependent protein catabolic process GO:0006511 206 0.026
positive regulation of protein phosphorylation GO:0001934 313 0.025
negative regulation of cell cycle phase transition GO:1901988 89 0.025
regulation of establishment of protein localization GO:0070201 242 0.025
synaptic vesicle endocytosis GO:0048488 2 0.025
single organism carbohydrate metabolic process GO:0044723 193 0.024
amine metabolic process GO:0009308 44 0.024
regulation of synaptic transmission GO:0050804 11 0.024
synaptic transmission GO:0007268 61 0.024
protein modification by small protein conjugation GO:0032446 342 0.023
carbohydrate derivative biosynthetic process GO:1901137 207 0.023
nuclear transport GO:0051169 179 0.022
female gamete generation GO:0007292 2 0.022
transmembrane transport GO:0055085 399 0.022
positive regulation of cell death GO:0010942 263 0.021
lipid biosynthetic process GO:0008610 177 0.021
cell projection organization GO:0030030 252 0.021
cellular protein catabolic process GO:0044257 261 0.021
cytoplasmic transport GO:0016482 379 0.020
cytokinesis GO:0000910 96 0.020
membrane lipid metabolic process GO:0006643 53 0.020
negative regulation of catalytic activity GO:0043086 335 0.020
organonitrogen compound biosynthetic process GO:1901566 200 0.020
oocyte differentiation GO:0009994 2 0.020
biological adhesion GO:0022610 331 0.019
cellular amine metabolic process GO:0044106 41 0.019
secretion GO:0046903 254 0.019
glycoprotein metabolic process GO:0009100 110 0.019
dephosphorylation GO:0016311 209 0.019
adult locomotory behavior GO:0008344 1 0.019
negative regulation of cellular component organization GO:0051129 235 0.019
cellular amino acid metabolic process GO:0006520 116 0.018
segmentation GO:0035282 4 0.018
regulation of protein transport GO:0051223 213 0.018
cell development GO:0048468 328 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
mitotic cell cycle phase transition GO:0044772 162 0.018
regulation of transferase activity GO:0051338 355 0.018
secretion by cell GO:0032940 226 0.018
mitotic cell cycle checkpoint GO:0007093 68 0.018
regulation of intracellular transport GO:0032386 195 0.018
positive regulation of atp metabolic process GO:1903580 20 0.018
positive regulation of phosphorylation GO:0042327 394 0.017
oxidation reduction process GO:0055114 396 0.017
nitrogen compound transport GO:0071705 191 0.017
glial cell migration GO:0008347 4 0.017
regulation of cellular amino acid metabolic process GO:0006521 6 0.017
hindbrain development GO:0030902 3 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.017
positive regulation of kinase activity GO:0033674 204 0.017
defense response GO:0006952 315 0.016
establishment of synaptic vesicle localization GO:0097480 5 0.016
covalent chromatin modification GO:0016569 254 0.016
organelle assembly GO:0070925 176 0.016
positive regulation of transferase activity GO:0051347 227 0.016
inorganic cation transmembrane transport GO:0098662 194 0.015
protein stabilization GO:0050821 64 0.015
regulation of synaptic plasticity GO:0048167 3 0.015
glycosylation GO:0070085 71 0.015
regulation of mitotic cell cycle phase transition GO:1901990 118 0.015
generation of neurons GO:0048699 152 0.015
regulation of defense response GO:0031347 154 0.014
chemical homeostasis GO:0048878 306 0.014
regulation of protein kinase activity GO:0045859 289 0.014
protein targeting GO:0006605 187 0.014
cellular ion homeostasis GO:0006873 168 0.014
regulation of mitotic cell cycle GO:0007346 189 0.014
regulation of cellular amine metabolic process GO:0033238 11 0.014
neurotransmitter secretion GO:0007269 4 0.014
actin cytoskeleton organization GO:0030036 207 0.014
immune response GO:0006955 307 0.014
cellular homeostasis GO:0019725 196 0.014
metal ion transport GO:0030001 272 0.014
spermatid differentiation GO:0048515 4 0.013
reproductive process GO:0022414 106 0.013
embryo development GO:0009790 123 0.013
protein acylation GO:0043543 138 0.013
negative regulation of organelle organization GO:0010639 126 0.013
negative regulation of protein modification process GO:0031400 200 0.013
protein polyubiquitination GO:0000209 110 0.013
regulation of neurotransmitter secretion GO:0046928 3 0.013
reactive oxygen species metabolic process GO:0072593 75 0.013
negative regulation of protein catabolic process GO:0042177 59 0.013
maintenance of location GO:0051235 112 0.013
response to biotic stimulus GO:0009607 276 0.013
establishment of nucleus localization GO:0040023 1 0.013
morphogenesis of embryonic epithelium GO:0016331 4 0.012
regulation of cellular component biogenesis GO:0044087 281 0.012
response to oxygen containing compound GO:1901700 369 0.012
g2 dna damage checkpoint GO:0031572 26 0.012
regulation of protein complex assembly GO:0043254 147 0.012
cardiac muscle cell contraction GO:0086003 4 0.012
oocyte development GO:0048599 1 0.012
regulation of cellular protein catabolic process GO:1903362 96 0.012
regulation of vesicle mediated transport GO:0060627 130 0.012
response to abiotic stimulus GO:0009628 336 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
cellular metal ion homeostasis GO:0006875 146 0.012
myosin filament assembly GO:0031034 2 0.012
positive regulation of cellular amine metabolic process GO:0033240 7 0.012
cellular cation homeostasis GO:0030003 163 0.012
cell part morphogenesis GO:0032990 137 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.012
small gtpase mediated signal transduction GO:0007264 78 0.012
myosin filament organization GO:0031033 2 0.012
negative regulation of proteasomal protein catabolic process GO:1901799 32 0.012
nerve development GO:0021675 4 0.012
protein glycosylation GO:0006486 62 0.012
cellular protein complex assembly GO:0043623 188 0.012
organic hydroxy compound metabolic process GO:1901615 147 0.012
protein dephosphorylation GO:0006470 81 0.012
regulation of proteasomal protein catabolic process GO:0061136 87 0.012
cellular chemical homeostasis GO:0055082 180 0.011
mapk cascade GO:0000165 288 0.011
cellular component morphogenesis GO:0032989 314 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
sensory perception of pain GO:0019233 4 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
divalent metal ion transport GO:0070838 152 0.011
negative regulation of apoptotic process GO:0043066 316 0.011
sphingolipid metabolic process GO:0006665 38 0.011
regulation of intracellular protein transport GO:0033157 123 0.011
positive regulation of protein kinase activity GO:0045860 190 0.011
ras protein signal transduction GO:0007265 73 0.011
cation transmembrane transport GO:0098655 238 0.011
blastoderm segmentation GO:0007350 2 0.011
alcohol metabolic process GO:0006066 114 0.011
regulation of cellular response to stress GO:0080135 244 0.011
negative regulation of programmed cell death GO:0043069 321 0.011
negative regulation of transferase activity GO:0051348 124 0.011
interspecies interaction between organisms GO:0044419 156 0.010
regulation of cellular ketone metabolic process GO:0010565 50 0.010
peripheral nervous system development GO:0007422 2 0.010
divalent inorganic cation transport GO:0072511 158 0.010
spermatid development GO:0007286 4 0.010
establishment of protein localization to organelle GO:0072594 172 0.010
establishment of organelle localization GO:0051656 59 0.010
cellular macromolecular complex assembly GO:0034622 324 0.010
regulation of multi organism process GO:0043900 157 0.010

TOR1A disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.159
inherited metabolic disorder DOID:655 242 0.159
central nervous system disease DOID:331 186 0.023
nervous system disease DOID:863 431 0.023
sensory system disease DOID:0050155 203 0.017
eye and adnexa disease DOID:1492 150 0.017
eye disease DOID:5614 149 0.017
disease of cellular proliferation DOID:14566 174 0.014
cancer DOID:162 167 0.012
organ system cancer DOID:0050686 164 0.011
musculoskeletal system disease DOID:17 223 0.011
neuropathy DOID:870 52 0.010
brain disease DOID:936 73 0.008
movement disease DOID:480 3 0.000