|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.847
|
Zebrafish |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.820
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.815
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.796
|
Rat |
|
|
cell development
|
GO:0048468 |
328 |
0.781
|
Mouse Rat |
|
|
organ formation
|
GO:0048645 |
3 |
0.778
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.665
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.664
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.655
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.646
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.630
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.619
|
Human Rat |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.580
|
Human |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.554
|
Mouse Rat |
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.524
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.503
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.499
|
Mouse Rat |
|
|
spinal cord development
|
GO:0021510 |
4 |
0.498
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.495
|
Human Worm |
|
|
extraocular skeletal muscle development
|
GO:0002074 |
1 |
0.488
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.476
|
Mouse Rat |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.467
|
Human Mouse |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.457
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.442
|
Mouse Rat |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.436
|
Human |
|
|
cell differentiation in spinal cord
|
GO:0021515 |
1 |
0.432
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.431
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.423
|
|
|
|
system process
|
GO:0003008 |
349 |
0.420
|
|
|
|
specification of organ identity
|
GO:0010092 |
3 |
0.393
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.370
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.361
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.360
|
Mouse Rat |
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.344
|
|
|
|
cardiac cell fate determination
|
GO:0060913 |
3 |
0.343
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.336
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.334
|
|
|
|
regulation of heart induction by regulation of canonical wnt signaling pathway
|
GO:0090081 |
1 |
0.329
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.329
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.315
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.314
|
Mouse Worm |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.312
|
Rat |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.305
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.300
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.298
|
Mouse Rat |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.298
|
Mouse Rat |
|
|
oxidative stress induced premature senescence
|
GO:0090403 |
3 |
0.295
|
Human |
|
|
brain development
|
GO:0007420 |
97 |
0.295
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.293
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.289
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.277
|
Human Rat |
|
|
head development
|
GO:0060322 |
108 |
0.270
|
Mouse |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.265
|
|
|
|
menstrual cycle phase
|
GO:0022601 |
2 |
0.263
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.254
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.240
|
Zebrafish |
|
|
embryo development
|
GO:0009790 |
123 |
0.237
|
Zebrafish Worm |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.235
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.233
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.228
|
Rat |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.228
|
Human |
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.216
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.215
|
Worm |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.212
|
Human |
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.212
|
Rat |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.205
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.202
|
Rat |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.202
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.202
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.198
|
|
|
|
forebrain regionalization
|
GO:0021871 |
3 |
0.198
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.198
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.197
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.195
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.192
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.189
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.186
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.186
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.184
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.183
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.182
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.181
|
|
|
|
negative regulation of stem cell differentiation
|
GO:2000737 |
22 |
0.180
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.177
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.176
|
Worm |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.174
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.170
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.166
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.166
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.162
|
|
|
|
bmp signaling pathway involved in heart development
|
GO:0061312 |
3 |
0.160
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.159
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.158
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.157
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.156
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.155
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.153
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.152
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.148
|
Zebrafish |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.144
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.143
|
Rat |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.142
|
Mouse |
|
|
vasculature development
|
GO:0001944 |
181 |
0.140
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.137
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.135
|
Rat |
|
|
protein import
|
GO:0017038 |
130 |
0.133
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.133
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.131
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.129
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.126
|
Zebrafish |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.121
|
Human Mouse |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.120
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.114
|
Mouse |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.113
|
Mouse Rat |
|
|
immune system development
|
GO:0002520 |
195 |
0.112
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.112
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.112
|
|
|
|
heart field specification
|
GO:0003128 |
2 |
0.112
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.111
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.110
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.110
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.109
|
Human Mouse |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.109
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.109
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.108
|
Human Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.107
|
|
|
|
cell proliferation in forebrain
|
GO:0021846 |
1 |
0.105
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.104
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.104
|
Human |
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.103
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.103
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.100
|
Human |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.099
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.099
|
Human Mouse |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.099
|
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.098
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.097
|
Mouse |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.097
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.097
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.096
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.095
|
Human Rat |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.093
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.093
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.092
|
Human |
|
|
ventral spinal cord development
|
GO:0021517 |
1 |
0.092
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.092
|
Mouse |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.090
|
Zebrafish |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.089
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.089
|
Human |
|
|
forelimb morphogenesis
|
GO:0035136 |
4 |
0.089
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.088
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.088
|
|
|
|
forebrain dorsal ventral pattern formation
|
GO:0021798 |
1 |
0.088
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.087
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.087
|
|
|
|
regulation of methylation dependent chromatin silencing
|
GO:0090308 |
3 |
0.086
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.086
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.086
|
Mouse |
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.086
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.085
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.085
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.084
|
Human |
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.084
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.083
|
Mouse Rat |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.083
|
Rat |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.083
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.083
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.083
|
|
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
13 |
0.082
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.081
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.080
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.079
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.078
|
Human |
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.078
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.077
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.077
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.077
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.077
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.076
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.076
|
|
|
|
phospholipid translocation
|
GO:0045332 |
2 |
0.076
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.074
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.073
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.072
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.072
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.072
|
Human Mouse |
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.071
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.071
|
|
|
|
embryonic forelimb morphogenesis
|
GO:0035115 |
4 |
0.071
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.069
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.068
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.068
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.067
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.067
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.066
|
|
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.066
|
|
|
|
growth
|
GO:0040007 |
202 |
0.066
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.066
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.065
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.064
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.064
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.064
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.064
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.064
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.063
|
Mouse |
|
|
kidney development
|
GO:0001822 |
53 |
0.063
|
Rat |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.063
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.062
|
|
|
|
positive regulation of insulin like growth factor receptor signaling pathway
|
GO:0043568 |
4 |
0.062
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.062
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.062
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.062
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.062
|
|
|
|
cartilage condensation
|
GO:0001502 |
1 |
0.061
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.061
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.061
|
Mouse |
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.060
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.059
|
|
|
|
cell fate specification
|
GO:0001708 |
8 |
0.059
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.059
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.059
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.059
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.059
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.058
|
Human |
|
|
mesenchymal to epithelial transition involved in metanephros morphogenesis
|
GO:0003337 |
4 |
0.058
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.058
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.057
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.057
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.057
|
Human |
|
|
regulation of cardiac muscle tissue growth
|
GO:0055021 |
4 |
0.057
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.057
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.057
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.056
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.056
|
Human Worm |
|
|
cell activation
|
GO:0001775 |
213 |
0.056
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.056
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.056
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.055
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
9 |
0.054
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.054
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.054
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.054
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.054
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.054
|
Human Mouse Rat |
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.053
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.053
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.053
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.052
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.052
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.052
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.051
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.051
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.051
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.051
|
|
|
|
negative regulation of alpha beta t cell proliferation
|
GO:0046642 |
1 |
0.051
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.050
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.050
|
Mouse |
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.050
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.050
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.050
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.050
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.050
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.050
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.050
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.050
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.050
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.049
|
Mouse |
|
|
regulation of heart induction
|
GO:0090381 |
2 |
0.049
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.049
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.049
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.049
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.049
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.049
|
|
|
|
endodermal mesodermal cell signaling
|
GO:0003133 |
3 |
0.049
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.048
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.048
|
Human |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.048
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.048
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.047
|
Mouse |
|
|
positive regulation of tooth mineralization
|
GO:0070172 |
2 |
0.047
|
|
|
|
pallium development
|
GO:0021543 |
10 |
0.047
|
Mouse |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.047
|
|
|
|
organic anion transport
|
GO:0015711 |
103 |
0.046
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.046
|
Mouse |
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.046
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.046
|
Human |
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.046
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.045
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.045
|
Human |
|
|
hormone metabolic process
|
GO:0042445 |
61 |
0.045
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.045
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.044
|
Human |
|
|
reproductive process
|
GO:0022414 |
106 |
0.043
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
2 |
0.043
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.043
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.043
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.042
|
Mouse |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.042
|
Rat |
|
|
reproduction
|
GO:0000003 |
63 |
0.042
|
Worm |
|
|
limbic system development
|
GO:0021761 |
3 |
0.042
|
Mouse |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.041
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.041
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.041
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.041
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.041
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.041
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.040
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.040
|
Mouse |
|
|
kidney epithelium development
|
GO:0072073 |
25 |
0.040
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
0.040
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.040
|
Mouse Rat |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.040
|
Mouse |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.040
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.039
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.039
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
20 |
0.039
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.039
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.039
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.039
|
Human |
|
|
negative regulation of cardiac muscle cell proliferation
|
GO:0060044 |
2 |
0.039
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.039
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
21 |
0.038
|
Rat |
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.038
|
Human |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.038
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.038
|
|
|
|
mating
|
GO:0007618 |
1 |
0.037
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.037
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.037
|
|
|
|
regulation of potassium ion transmembrane transport
|
GO:1901379 |
20 |
0.037
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.037
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.036
|
Mouse Rat |
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.036
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.036
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.036
|
Human |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.036
|
|
|
|
membrane protein proteolysis
|
GO:0033619 |
38 |
0.036
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.036
|
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.036
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.036
|
Rat |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.036
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.036
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.036
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.036
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.035
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.035
|
|
|
|
cell fate commitment involved in pattern specification
|
GO:0060581 |
1 |
0.035
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.035
|
|
|
|
ventral spinal cord interneuron differentiation
|
GO:0021514 |
1 |
0.035
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.035
|
Mouse |
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.035
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.035
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.035
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.034
|
|
|
|
embryonic camera type eye morphogenesis
|
GO:0048596 |
2 |
0.034
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.034
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.034
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.034
|
Human |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.034
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.034
|
Mouse |
|
|
metanephric nephron epithelium development
|
GO:0072243 |
4 |
0.034
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.034
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.034
|
Rat |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.033
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.033
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.033
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.033
|
Human |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.033
|
|
|
|
mesodermal cell fate specification
|
GO:0007501 |
2 |
0.033
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.033
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.033
|
|
|
|
endocrine system development
|
GO:0035270 |
26 |
0.032
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.032
|
|
|
|
menstruation
|
GO:0042703 |
1 |
0.032
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.032
|
|
|
|
regulation of organ formation
|
GO:0003156 |
4 |
0.032
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.032
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.032
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.031
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.031
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.031
|
|
|
|
positive regulation of response to dna damage stimulus
|
GO:2001022 |
43 |
0.031
|
Mouse |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.031
|
Mouse |
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.031
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.030
|
|
|
|
regulation of blood vessel size
|
GO:0050880 |
18 |
0.030
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.030
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.030
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.030
|
Human |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.030
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.030
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.030
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.030
|
|
|
|
negative regulation of striated muscle tissue development
|
GO:0045843 |
11 |
0.030
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.030
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.029
|
Mouse |
|
|
keratinocyte differentiation
|
GO:0030216 |
36 |
0.029
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.029
|
|
|
|
regulation of epithelial cell differentiation involved in kidney development
|
GO:2000696 |
4 |
0.029
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.029
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.029
|
Mouse |
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.029
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.029
|
Human Mouse |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.029
|
Human Mouse Rat |
|
|
negative regulation of heart growth
|
GO:0061117 |
2 |
0.029
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.029
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.029
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.028
|
|
|
|
regulation of cardioblast differentiation
|
GO:0051890 |
4 |
0.028
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.028
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
29 |
0.028
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
24 |
0.028
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.028
|
|
|
|
embryonic camera type eye formation
|
GO:0060900 |
2 |
0.028
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.028
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.028
|
Rat |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.028
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.028
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.028
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.028
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.028
|
Human |
|
|
fibroblast proliferation
|
GO:0048144 |
33 |
0.028
|
Human |
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.028
|
|
|
|
trophectodermal cell differentiation
|
GO:0001829 |
3 |
0.028
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.028
|
|
|
|
negative regulation of muscle tissue development
|
GO:1901862 |
11 |
0.028
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.027
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.027
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.027
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.027
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.027
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.027
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.027
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.027
|
Human |
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.027
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.027
|
|
|
|
negative regulation of cardiac muscle tissue growth
|
GO:0055022 |
2 |
0.027
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.027
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.027
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.027
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.027
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.026
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.026
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.026
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.026
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.026
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.026
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.026
|
Human |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.026
|
Human |
|
|
behavior
|
GO:0007610 |
112 |
0.026
|
|
|
|
heart induction
|
GO:0003129 |
4 |
0.025
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.025
|
|
|
|
embryonic hindlimb morphogenesis
|
GO:0035116 |
2 |
0.025
|
|
|
|
cardiac right ventricle morphogenesis
|
GO:0003215 |
3 |
0.025
|
|
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.025
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.025
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.025
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.025
|
Rat |
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.025
|
|
|
|
regulation of thyroid hormone generation
|
GO:2000609 |
2 |
0.025
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.025
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
23 |
0.025
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.025
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.025
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.025
|
Human Mouse Rat |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.025
|
Mouse |
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.025
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.025
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.025
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.025
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.025
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.025
|
|
|
|
right ventricular cardiac muscle tissue morphogenesis
|
GO:0003221 |
2 |
0.025
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.025
|
Mouse |
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.025
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.025
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.025
|
Human |
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.024
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.024
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.024
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation
|
GO:0003257 |
3 |
0.024
|
|
|
|
metanephric nephron tubule development
|
GO:0072234 |
3 |
0.024
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.024
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.024
|
|
|
|
bmp signaling pathway involved in heart induction
|
GO:0003130 |
3 |
0.024
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.024
|
|
|
|
spinal cord dorsal ventral patterning
|
GO:0021513 |
2 |
0.024
|
|
