|
|
negative regulation of neurological system process
|
GO:0031645 |
2 |
0.996
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
4 |
0.994
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.965
|
Human |
|
|
osteoclast differentiation
|
GO:0030316 |
21 |
0.963
|
Human |
|
|
jnk cascade
|
GO:0007254 |
80 |
0.943
|
Human |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.931
|
Human |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.913
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.897
|
Human |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.896
|
Human |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.887
|
Human |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.883
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.878
|
Human |
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.878
|
Human |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.869
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.867
|
Human |
|
|
transmission of nerve impulse
|
GO:0019226 |
11 |
0.865
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.840
|
Human |
|
|
cytokine production
|
GO:0001816 |
247 |
0.837
|
Human |
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.835
|
Human |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.833
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.832
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.815
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.806
|
Human |
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.804
|
|
|
|
positive regulation of protein kinase c signaling
|
GO:0090037 |
5 |
0.803
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.790
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.788
|
Human |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.786
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.779
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.771
|
Human |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.762
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.760
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.753
|
Human |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.752
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.751
|
Human |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.748
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.743
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.741
|
|
|
|
tnfsf11 mediated signaling pathway
|
GO:0071847 |
2 |
0.726
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.725
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.723
|
Human |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.720
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.718
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.707
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.706
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.704
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.703
|
Human |
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.702
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.702
|
Human |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.702
|
Human |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.701
|
Human |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.700
|
Human |
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.694
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.693
|
Human |
|
|
response to other organism
|
GO:0051707 |
261 |
0.690
|
Human |
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.688
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.687
|
Human |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.686
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.684
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.679
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.679
|
Human |
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.677
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.670
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.660
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.651
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.648
|
Human |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.642
|
|
|
|
regulation of cdc42 protein signal transduction
|
GO:0032489 |
14 |
0.641
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.637
|
|
|
|
neuronal action potential
|
GO:0019228 |
9 |
0.636
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.618
|
|
|
|
membrane protein proteolysis
|
GO:0033619 |
38 |
0.618
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.609
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.603
|
Human |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.601
|
|
|
|
positive regulation of erk1 and erk2 cascade via tnfsf11 mediated signaling
|
GO:0071848 |
2 |
0.589
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.572
|
|
|
|
regulation of cdc42 gtpase activity
|
GO:0043088 |
10 |
0.572
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.567
|
|
|
|
negative regulation of alpha beta t cell proliferation
|
GO:0046642 |
1 |
0.563
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.563
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.553
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
0.550
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.541
|
Human |
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.538
|
Human |
|
|
regulation of endothelial cell apoptotic process
|
GO:2000351 |
24 |
0.534
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.532
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.530
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.526
|
Human |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.526
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.524
|
|
|
|
positive regulation of endothelial cell apoptotic process
|
GO:2000353 |
8 |
0.521
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.520
|
Human |
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.517
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.513
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.508
|
Human |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.507
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.504
|
Human |
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.503
|
Human |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.497
|
Human |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.494
|
Human |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.485
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.484
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.481
|
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
11 |
0.479
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.479
|
Human |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.475
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.475
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.473
|
Human |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.470
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.469
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.468
|
Human |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.459
|
|
|
|
membrane protein ectodomain proteolysis
|
GO:0006509 |
33 |
0.443
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.436
|
Human |
|
|
defense response
|
GO:0006952 |
315 |
0.433
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.433
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.431
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.416
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.408
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.405
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.394
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.393
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.389
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.389
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.388
|
Human |
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.386
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
22 |
0.384
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.383
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.381
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.381
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.377
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.375
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.372
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.370
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.370
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.370
|
Human |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.368
|
|
|
|
positive regulation of cytokine secretion involved in immune response
|
GO:0002741 |
2 |
0.362
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.362
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.361
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.358
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
27 |
0.352
|
Human |
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.352
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.345
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.341
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.340
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.340
|
Human |
|
|
positive regulation of membrane protein ectodomain proteolysis
|
GO:0051044 |
13 |
0.335
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.329
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.324
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.323
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.317
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
25 |
0.316
|
Human |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.315
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.314
|
|
|
|
protein kinase c signaling
|
GO:0070528 |
17 |
0.313
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.312
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.310
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.306
|
Human |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.299
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.294
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.291
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.273
|
Human |
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.273
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
38 |
0.273
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.272
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.270
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.269
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.268
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.264
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.264
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.262
|
Human |
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.255
|
Human |
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.249
|
Human |
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.249
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.247
|
Human |
|
|
immune response
|
GO:0006955 |
307 |
0.245
|
Human |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.240
|
Human |
|
|
myelination
|
GO:0042552 |
6 |
0.237
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.234
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.233
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.232
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.231
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.230
|
Human |
|
|
regulation of protein kinase c signaling
|
GO:0090036 |
8 |
0.230
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.230
|
|
|
|
negative regulation of myelination
|
GO:0031642 |
1 |
0.225
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.224
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.224
|
|
|
|
immunoglobulin secretion
|
GO:0048305 |
1 |
0.223
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.221
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.220
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
25 |
0.220
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.218
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.216
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.214
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
21 |
0.213
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.212
|
Human |
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.211
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.211
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.211
|
|
|
|
neuronal stem cell division
|
GO:0036445 |
1 |
0.210
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.200
|
Human |
|
|
regulation of membrane protein ectodomain proteolysis
|
GO:0051043 |
17 |
0.199
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.198
|
Human |
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.198
|
|
|
|
endothelial cell apoptotic process
|
GO:0072577 |
26 |
0.190
|
|
|
|
system process
|
GO:0003008 |
349 |
0.187
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.185
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.183
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.181
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.181
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.180
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.179
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.172
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.171
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.170
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.163
|
Human |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.161
|
Human |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.159
|
Human |
|
|
action potential
|
GO:0001508 |
34 |
0.157
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.156
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
34 |
0.154
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.152
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.152
|
Human |
|
|
regulation of myelination
|
GO:0031641 |
1 |
0.152
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.150
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.149
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.148
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.145
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.144
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.140
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.139
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.137
|
Human |
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.136
|
Human |
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
27 |
0.134
|
Human |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.134
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.132
|
|
|
|
regulation of lymphocyte migration
|
GO:2000401 |
22 |
0.131
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.128
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.127
|
Human |
|
|
regulation of plasma lipoprotein particle levels
|
GO:0097006 |
32 |
0.127
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.127
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.125
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.124
|
Human |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.124
|
Human |
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.123
|
Human |
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.122
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.115
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.114
|
|
|
|
positive regulation of tumor necrosis factor biosynthetic process
|
GO:0042535 |
5 |
0.111
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.111
|
Human |
|
|
cell activation
|
GO:0001775 |
213 |
0.108
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.108
|
|
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
9 |
0.106
|
Human |
|
|
cell proliferation in forebrain
|
GO:0021846 |
1 |
0.106
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.105
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.103
|
Human |
|
|
positive regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042511 |
8 |
0.102
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.102
|
Human |
|
|
regulation of immunoglobulin secretion
|
GO:0051023 |
1 |
0.100
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.098
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
29 |
0.095
|
Human |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.095
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.094
|
|
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.092
|
Human |
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
18 |
0.092
|
Human |
|
|
regulation of immunoglobulin production
|
GO:0002637 |
4 |
0.090
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.089
|
Human |
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.088
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.088
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.088
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.088
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
1 |
0.085
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.082
|
Human |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.082
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.081
|
|
|
|
neuroblast division
|
GO:0055057 |
1 |
0.080
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
2 |
0.080
|
|
|
|
positive regulation of fatty acid transport
|
GO:2000193 |
3 |
0.079
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.078
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.076
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.074
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.073
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.073
|
Human |
|
|
activation of nf kappab inducing kinase activity
|
GO:0007250 |
9 |
0.073
|
Human |
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.072
|
Human |
|
|
regulation of t cell migration
|
GO:2000404 |
14 |
0.071
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.071
|
Human |
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
4 |
0.070
|
|
|
|
sterol homeostasis
|
GO:0055092 |
28 |
0.068
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.068
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
22 |
0.067
|
Human |
|
|
regulation of neurological system process
|
GO:0031644 |
6 |
0.064
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.063
|
|
|
|
positive regulation of t cell cytokine production
|
GO:0002726 |
4 |
0.063
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.062
|
|
|
|
positive regulation of isotype switching
|
GO:0045830 |
2 |
0.062
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.062
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.060
|
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
8 |
0.060
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.060
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.058
|
Human |
|
|
cell development
|
GO:0048468 |
328 |
0.056
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.056
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.056
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.056
|
|
|
|
positive regulation of organic acid transport
|
GO:0032892 |
3 |
0.055
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.055
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.055
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.054
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.054
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.054
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.053
|
|
|
|
positive regulation of cytokine production involved in immune response
|
GO:0002720 |
6 |
0.053
|
Human |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.053
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.053
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
3 |
0.052
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.051
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.051
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.050
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.050
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.050
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.050
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.050
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.049
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.049
|
Human |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.048
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.048
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.048
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.048
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.047
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.047
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.047
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
23 |
0.047
|
Human |
|
|
cell junction organization
|
GO:0034330 |
79 |
0.047
|
|
|
|
cytokine secretion involved in immune response
|
GO:0002374 |
7 |
0.046
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.045
|
Human |
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.045
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
47 |
0.045
|
|
|
|
cholesterol homeostasis
|
GO:0042632 |
28 |
0.044
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.044
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.044
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
29 |
0.044
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.043
|
Human |
|
|
positive regulation of t cell migration
|
GO:2000406 |
13 |
0.043
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.043
|
Human |
|
|
activation of immune response
|
GO:0002253 |
114 |
0.042
|
Human |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.042
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.042
|
Human |
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.041
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.041
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.041
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.041
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.041
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.040
|
|
|
|
positive regulation of icosanoid secretion
|
GO:0032305 |
3 |
0.040
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.040
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.040
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.039
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.039
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
40 |
0.039
|
Human |
|
|
nik nf kappab signaling
|
GO:0038061 |
12 |
0.039
|
Human |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.038
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.038
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
11 |
0.038
|
Human |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.038
|
Human |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.038
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.037
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.037
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
6 |
0.036
|
|
|
|
protein kinase c activating g protein coupled receptor signaling pathway
|
GO:0007205 |
2 |
0.036
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.036
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.036
|
|
|
|
positive regulation of cdc42 gtpase activity
|
GO:0043089 |
6 |
0.036
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.035
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.035
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
42 |
0.035
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.035
|
|
|
|
regulation of dna templated transcription elongation
|
GO:0032784 |
23 |
0.034
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.034
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.034
|
|
|
|
tumor necrosis factor biosynthetic process
|
GO:0042533 |
8 |
0.034
|
|
|
|
organic acid transport
|
GO:0015849 |
65 |
0.033
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.033
|
|
|
|
prostaglandin secretion
|
GO:0032310 |
2 |
0.033
|
|
|
|
t cell migration
|
GO:0072678 |
16 |
0.032
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.032
|
|
|
|
muscle cell fate commitment
|
GO:0042693 |
4 |
0.032
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.032
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.032
|
Human |
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.032
|
Human |
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.031
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.031
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.031
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.031
|
|
|
|
regulation of t cell cytokine production
|
GO:0002724 |
10 |
0.030
|
Human |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.030
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.030
|
Human |
|
|
regulation of interleukin 2 production
|
GO:0032663 |
19 |
0.030
|
Human |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.029
|
|
|
|
regulation of icosanoid secretion
|
GO:0032303 |
4 |
0.028
|
|
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
4 |
0.028
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.028
|
|
|
|
positive regulation of protein homodimerization activity
|
GO:0090073 |
5 |
0.028
|
Human |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.028
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.028
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.028
|
|
|
|
lymphocyte migration
|
GO:0072676 |
28 |
0.027
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.027
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.027
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.027
|
|
|
|
positive regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031666 |
4 |
0.027
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.027
|
|
|
|
axon ensheathment
|
GO:0008366 |
6 |
0.027
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.027
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.027
|
Human |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.026
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.026
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.026
|
|
|
|
transcription elongation from rna polymerase ii promoter
|
GO:0006368 |
18 |
0.026
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.026
|
|
|
|
negative regulation of jnk cascade
|
GO:0046329 |
16 |
0.026
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
13 |
0.026
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.026
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
33 |
0.026
|
|
|
|
protein autoubiquitination
|
GO:0051865 |
37 |
0.026
|
Human |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.026
|
|
|
|
organic anion transport
|
GO:0015711 |
103 |
0.025
|
|
|
|
regulation of anion transport
|
GO:0044070 |
25 |
0.025
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.025
|
Human |
|
|
regulation of isotype switching
|
GO:0045191 |
2 |
0.025
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.025
|
Human |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.025
|
Human |
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.024
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.024
|
|
|
|
prostaglandin transport
|
GO:0015732 |
2 |
0.024
|
|
|
|
positive regulation of transcription regulatory region dna binding
|
GO:2000679 |
8 |
0.024
|
Human |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.024
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.024
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.024
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.023
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.023
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.023
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.023
|
|
|
|
thalamus development
|
GO:0021794 |
2 |
0.023
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.023
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.023
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.023
|
|
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.022
|
Human |
|
|
dna templated transcription elongation
|
GO:0006354 |
25 |
0.022
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.022
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.022
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.022
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.021
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.021
|
|
|
|
negative regulation of i kappab kinase nf kappab signaling
|
GO:0043124 |
32 |
0.021
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.021
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.021
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.021
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.021
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.021
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.021
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.020
|
|
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.020
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.020
|
|
|
|
positive regulation of binding
|
GO:0051099 |
45 |
0.020
|
Human |
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.020
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.020
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.020
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.020
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
16 |
0.020
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.020
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.020
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.019
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.019
|
|
|
|
plasma lipoprotein particle clearance
|
GO:0034381 |
16 |
0.019
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.019
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
63 |
0.019
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.019
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.019
|
|
|
|
cholesterol transport
|
GO:0030301 |
39 |
0.019
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.019
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.019
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.019
|
|
