Homo sapiens

268 known processes

TRIM27

tripartite motif containing 27

(Aliases: RFP,RNF76)

TRIM27 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation GO:0032446 342 0.979
protein ubiquitination GO:0016567 314 0.882
protein polyubiquitination GO:0000209 110 0.781
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.772
Human
cellular macromolecule catabolic process GO:0044265 380 0.770
Human
protein autoubiquitination GO:0051865 37 0.753
Human
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.541
Human
ubiquitin dependent protein catabolic process GO:0006511 206 0.451
Human
modification dependent protein catabolic process GO:0019941 209 0.415
Human
protein k63 linked ubiquitination GO:0070534 31 0.412
cellular protein catabolic process GO:0044257 261 0.379
Human
regulation of cell cycle GO:0051726 393 0.372
Human
modification dependent macromolecule catabolic process GO:0043632 212 0.329
Human
i kappab kinase nf kappab signaling GO:0007249 166 0.256
Human
positive regulation of cell death GO:0010942 263 0.238
Human
protein k48 linked ubiquitination GO:0070936 38 0.238
cellular response to dna damage stimulus GO:0006974 379 0.209
post embryonic development GO:0009791 2 0.196
regulation of protein ubiquitination GO:0031396 95 0.193
Human
response to other organism GO:0051707 261 0.179
Human
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.175
Human
protein monoubiquitination GO:0006513 39 0.171
Human
proteasomal protein catabolic process GO:0010498 176 0.167
defense response GO:0006952 315 0.164
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.157
immune response GO:0006955 307 0.151
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.144
viral release from host cell GO:0019076 21 0.135
Human Mouse
positive regulation of apoptotic process GO:0043065 246 0.132
Human
negative regulation of cell death GO:0060548 345 0.124
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.113
apoptotic signaling pathway GO:0097190 268 0.113
Human
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.113
divalent metal ion transport GO:0070838 152 0.108
cell cycle phase transition GO:0044770 173 0.106
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.104
Human
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.101
Human
maintenance of location GO:0051235 112 0.101
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.098
regulation of cytokine production GO:0001817 232 0.095
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.094
segmentation GO:0035282 4 0.092
positive regulation of innate immune response GO:0045089 79 0.091
Human
mitotic cell cycle GO:0000278 326 0.091
regulation of cell cycle process GO:0010564 266 0.088
protein catabolic process GO:0030163 325 0.085
Human
glycoprotein biosynthetic process GO:0009101 91 0.080
intrinsic apoptotic signaling pathway GO:0097193 127 0.079
metal ion transport GO:0030001 272 0.076
regulation of endopeptidase activity GO:0052548 170 0.076
negative regulation of protein metabolic process GO:0051248 391 0.072
vesicle mediated transport GO:0016192 371 0.071
regulation of proteolysis GO:0030162 293 0.069
Human
response to radiation GO:0009314 151 0.068
viral gene expression GO:0019080 35 0.066
cellular response to cytokine stimulus GO:0071345 181 0.066
calcium ion transport GO:0006816 147 0.064
response to external biotic stimulus GO:0043207 261 0.062
Human
oogenesis GO:0048477 2 0.062
posttranscriptional regulation of gene expression GO:0010608 213 0.062
Human
negative regulation of apoptotic process GO:0043066 316 0.061
positive regulation of programmed cell death GO:0043068 249 0.060
Human
defense response to virus GO:0051607 71 0.058
Human
blastoderm segmentation GO:0007350 2 0.058
positive regulation of cellular component organization GO:0051130 376 0.057
response to cytokine GO:0034097 232 0.057
androgen receptor signaling pathway GO:0030521 34 0.055
Human
protein k11 linked ubiquitination GO:0070979 24 0.055
pharynx development GO:0060465 1 0.054
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.054
regulation of mitotic cell cycle GO:0007346 189 0.054
response to growth factor GO:0070848 205 0.052
retina layer formation GO:0010842 3 0.052
cell development GO:0048468 328 0.051
cellular ion homeostasis GO:0006873 168 0.051
chromatin organization GO:0006325 351 0.051
protein sumoylation GO:0016925 25 0.051
positive regulation of locomotion GO:0040017 186 0.050
Human
response to organic cyclic compound GO:0014070 204 0.049
response to bacterium GO:0009617 144 0.048
Human
intracellular receptor signaling pathway GO:0030522 104 0.047
Human
cellular response to lipid GO:0071396 127 0.047
Human
cellular amino acid metabolic process GO:0006520 116 0.046
histone modification GO:0016570 251 0.046
viral process GO:0016032 146 0.045
viral life cycle GO:0019058 132 0.044
cellular cation homeostasis GO:0030003 163 0.044
female gamete generation GO:0007292 2 0.044
glycoprotein metabolic process GO:0009100 110 0.043
sequestering of calcium ion GO:0051208 17 0.043
immune effector process GO:0002252 159 0.043
Human
covalent chromatin modification GO:0016569 254 0.043
mitotic cell cycle process GO:1903047 286 0.042
cytokine mediated signaling pathway GO:0019221 109 0.042
positive regulation of organelle organization GO:0010638 195 0.042
response to abiotic stimulus GO:0009628 336 0.042
oocyte development GO:0048599 1 0.042
response to biotic stimulus GO:0009607 276 0.041
Human
regulation of response to dna damage stimulus GO:2001020 94 0.041
anterior posterior axis specification GO:0009948 2 0.040
negative regulation of intracellular signal transduction GO:1902532 183 0.040
regulation of cellular response to stress GO:0080135 244 0.039
glycosylation GO:0070085 71 0.039
regulation of innate immune response GO:0045088 97 0.039
Human
defense response to other organism GO:0098542 129 0.038
Human
regulation of defense response GO:0031347 154 0.038
Human
oocyte differentiation GO:0009994 2 0.038
regulation of cellular amino acid metabolic process GO:0006521 6 0.037
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.037
cofactor metabolic process GO:0051186 87 0.037
positive regulation of immune system process GO:0002684 283 0.036
Human
negative regulation of mitotic cell cycle GO:0045930 102 0.035
negative regulation of programmed cell death GO:0043069 321 0.035
regulation of mapk cascade GO:0043408 262 0.035
Human
regulation of mitotic cell cycle phase transition GO:1901990 118 0.035
innate immune response GO:0045087 178 0.033
ion homeostasis GO:0050801 230 0.033
chromatin modification GO:0016568 298 0.032
cellular modified amino acid metabolic process GO:0006575 64 0.032
protein acylation GO:0043543 138 0.032
cellular metal ion homeostasis GO:0006875 146 0.032
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.032
amine metabolic process GO:0009308 44 0.031
retrograde transport endosome to golgi GO:0042147 45 0.031
negative regulation of phosphorylation GO:0042326 174 0.031
metal ion homeostasis GO:0055065 169 0.031
regulation of cellular ketone metabolic process GO:0010565 50 0.031
positive regulation of proteolysis GO:0045862 142 0.030
response to virus GO:0009615 126 0.030
Human
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.030
response to lipid GO:0033993 206 0.030
Human
response to oxygen containing compound GO:1901700 369 0.030
Human
sequestering of metal ion GO:0051238 24 0.030
negative regulation of cellular protein metabolic process GO:0032269 353 0.030
regulation of apoptotic signaling pathway GO:2001233 175 0.029
Human
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.029
anterior posterior axis specification embryo GO:0008595 2 0.029
cellular response to oxygen containing compound GO:1901701 276 0.029
Human
cellular response to growth factor stimulus GO:0071363 197 0.029
cellular response to endogenous stimulus GO:0071495 336 0.028
regulation of cell cycle phase transition GO:1901987 126 0.028
negative regulation of sequestering of calcium ion GO:0051283 41 0.028
regulation of locomotion GO:0040012 329 0.028
Human
cellular homeostasis GO:0019725 196 0.028
response to molecule of bacterial origin GO:0002237 82 0.027
Human
cation transport GO:0006812 331 0.027
negative regulation of catalytic activity GO:0043086 335 0.027
multicellular organismal aging GO:0010259 3 0.027
positive regulation of immune response GO:0050778 159 0.027
Human
multi organism metabolic process GO:0044033 41 0.026
regulation of gene expression epigenetic GO:0040029 73 0.026
response to caffeine GO:0031000 3 0.026
regulation of protein localization GO:0032880 296 0.026
positive regulation of developmental process GO:0051094 314 0.026
positive regulation of phosphorylation GO:0042327 394 0.025
Human
regulation of secretion GO:0051046 194 0.025
positive regulation of apoptotic signaling pathway GO:2001235 70 0.025
Human
macromolecule glycosylation GO:0043413 63 0.025
positive regulation of catabolic process GO:0009896 310 0.025
regulation of transferase activity GO:0051338 355 0.025
divalent inorganic cation transport GO:0072511 158 0.025
cellular response to inorganic substance GO:0071241 45 0.025
cellular response to nitrogen compound GO:1901699 144 0.025
protein acetylation GO:0006473 116 0.024
cell cycle checkpoint GO:0000075 117 0.024
mitotic cell cycle checkpoint GO:0007093 68 0.024
nervous system development GO:0007399 293 0.024
lipid biosynthetic process GO:0008610 177 0.024
regulation of ion homeostasis GO:2000021 73 0.024
regulation of cell differentiation GO:0045595 393 0.024
mitotic dna damage checkpoint GO:0044773 28 0.023
negative regulation of protein ubiquitination GO:0031397 35 0.023
Human
negative regulation of kinase activity GO:0033673 106 0.023
cell division GO:0051301 168 0.023
determination of adult lifespan GO:0008340 2 0.023
regulation of protein kinase activity GO:0045859 289 0.023
tripartite regional subdivision GO:0007351 2 0.023
translation GO:0006412 132 0.023
carbohydrate derivative biosynthetic process GO:1901137 207 0.023
dna repair GO:0006281 198 0.023
regulation of cysteine type endopeptidase activity GO:2000116 127 0.022
cellular divalent inorganic cation homeostasis GO:0072503 128 0.022
lens development in camera type eye GO:0002088 2 0.022
positive regulation of cell proliferation GO:0008284 301 0.022
carbohydrate metabolic process GO:0005975 207 0.022
regulation of viral release from host cell GO:1902186 20 0.022
Human Mouse
negative regulation of multicellular organismal process GO:0051241 317 0.022
entry into host GO:0044409 25 0.022
Human
negative regulation of transport GO:0051051 176 0.022
regulation of intracellular transport GO:0032386 195 0.022
Human
negative regulation of apoptotic signaling pathway GO:2001234 97 0.022
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.022
Human
single organism cellular localization GO:1902580 332 0.022
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.022
regulation of cytokine mediated signaling pathway GO:0001959 41 0.022
regulation of immune response GO:0050776 201 0.021
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.021
Human
anatomical structure formation involved in morphogenesis GO:0048646 284 0.021
neuron death GO:0070997 65 0.021
sulfur compound metabolic process GO:0006790 101 0.021
single organism reproductive process GO:0044702 98 0.021
positive regulation of cellular catabolic process GO:0031331 284 0.021
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.021
negative regulation of transferase activity GO:0051348 124 0.021
negative regulation of cell cycle process GO:0010948 121 0.021
alpha amino acid metabolic process GO:1901605 72 0.021
dna integrity checkpoint GO:0031570 71 0.021
response to ionizing radiation GO:0010212 65 0.020
inorganic ion transmembrane transport GO:0098660 231 0.020
positive regulation of cytokine production GO:0001819 167 0.020
Human
intracellular protein transport GO:0006886 270 0.020
cytoplasmic transport GO:0016482 379 0.020
regulation of viral transcription GO:0046782 34 0.020
negative regulation of viral process GO:0048525 66 0.020
calcium ion transmembrane transport GO:0070588 76 0.020
mitotic dna integrity checkpoint GO:0044774 30 0.019
regulation of immune effector process GO:0002697 91 0.019
Human
positive regulation of cellular amine metabolic process GO:0033240 7 0.019
protein localization to nucleus GO:0034504 136 0.019
dna damage checkpoint GO:0000077 68 0.019
positive regulation of peptidase activity GO:0010952 88 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.019
negative regulation of cell proliferation GO:0008285 228 0.018
negative regulation of cell differentiation GO:0045596 171 0.018
secretion by cell GO:0032940 226 0.018
regulation of protein stability GO:0031647 87 0.018
Human
protein glycosylation GO:0006486 62 0.018
interspecies interaction between organisms GO:0044419 156 0.018
negative regulation of homeostatic process GO:0032845 59 0.018
spindle organization GO:0007051 53 0.018
regulation of multi organism process GO:0043900 157 0.018
cellular protein complex assembly GO:0043623 188 0.018
negative regulation of intracellular transport GO:0032387 60 0.018
Human
dna modification GO:0006304 27 0.017
histone ubiquitination GO:0016574 31 0.017
nuclear transport GO:0051169 179 0.017
cation transmembrane transport GO:0098655 238 0.017
chromosome segregation GO:0007059 114 0.017
regulation of cell development GO:0060284 161 0.017
regulation of protein transport GO:0051223 213 0.017
response to transforming growth factor beta GO:0071559 94 0.017
divalent inorganic cation homeostasis GO:0072507 136 0.017
microtubule cytoskeleton organization GO:0000226 176 0.017
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.017
Human
negative regulation of protein modification process GO:0031400 200 0.017
positive regulation of endopeptidase activity GO:0010950 84 0.017
negative regulation of cytokine production GO:0001818 82 0.017
regulation of sequestering of calcium ion GO:0051282 41 0.017
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.017
microtubule based process GO:0007017 210 0.016
mitotic cell cycle phase transition GO:0044772 162 0.016
protein oligomerization GO:0051259 173 0.016
cell activation GO:0001775 213 0.016
viral transcription GO:0019083 35 0.016
cellular amine metabolic process GO:0044106 41 0.016
single organism carbohydrate metabolic process GO:0044723 193 0.016
regulation of cytokine secretion GO:0050707 57 0.016
positive regulation of cell differentiation GO:0045597 211 0.015
negative regulation of protein kinase activity GO:0006469 98 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.015
Human
cytosolic calcium ion transport GO:0060401 48 0.015
response to light stimulus GO:0009416 87 0.015
positive regulation of cell motility GO:2000147 177 0.015
cytokine production GO:0001816 247 0.015
regulation of tumor necrosis factor production GO:0032680 43 0.015
enzyme linked receptor protein signaling pathway GO:0007167 303 0.015
lymphocyte proliferation GO:0046651 70 0.015
regulation of cell motility GO:2000145 299 0.015
response to hormone GO:0009725 175 0.015
positive regulation of protein ubiquitination GO:0031398 53 0.015
developmental programmed cell death GO:0010623 3 0.015
regulation of protein maturation GO:1903317 150 0.015
Human
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.015
ras protein signal transduction GO:0007265 73 0.014
t cell differentiation in thymus GO:0033077 4 0.014
endocytosis GO:0006897 159 0.014
cytokinesis GO:0000910 96 0.014
regulation of cell activation GO:0050865 125 0.014
neurogenesis GO:0022008 169 0.014
regulation of histone modification GO:0031056 47 0.014
toll signaling pathway GO:0008063 2 0.014
response to nutrient levels GO:0031667 81 0.014
g2 dna damage checkpoint GO:0031572 26 0.014
regulation of leukocyte proliferation GO:0070663 67 0.014
response to hyperoxia GO:0055093 4 0.014
negative regulation of immune system process GO:0002683 136 0.014
positive regulation of defense response GO:0031349 87 0.014
Human
negative regulation of cell cycle GO:0045786 193 0.014
regulation of reactive oxygen species metabolic process GO:2000377 41 0.014
protein methylation GO:0006479 74 0.013
regulation of phagocytosis engulfment GO:0060099 2 0.013
lymphocyte activation GO:0046649 133 0.013
response to nutrient GO:0007584 20 0.013
positive regulation of histone modification GO:0031058 29 0.013
regulation of interleukin 2 secretion GO:1900040 2 0.013
methylation dependent chromatin silencing GO:0006346 3 0.013
positive regulation of hydrolase activity GO:0051345 331 0.013
t cell activation GO:0042110 99 0.013
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.013
Human
negative regulation of protein maturation GO:1903318 142 0.013
Human
positive regulation of cellular component biogenesis GO:0044089 158 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.013
locomotory behavior GO:0007626 1 0.013
negative regulation of proteolysis GO:0045861 132 0.013
Human
negative regulation of cell cycle phase transition GO:1901988 89 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
response to extracellular stimulus GO:0009991 85 0.013
positive regulation of cell cycle process GO:0090068 106 0.013
activation of innate immune response GO:0002218 55 0.013
Human
notch signaling pathway GO:0007219 31 0.012
regulation of ion transport GO:0043269 189 0.012
regulation of neurogenesis GO:0050767 82 0.012
regulation of transmembrane transport GO:0034762 139 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.012
Human
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:2000059 3 0.012
Human
negative regulation of protein transport GO:0051224 75 0.012
cellular response to organic cyclic compound GO:0071407 127 0.012
calcium ion homeostasis GO:0055074 122 0.012
innate immune response activating signal transduction GO:0002758 48 0.012
Human
regulation of protein acetylation GO:1901983 25 0.012
cation homeostasis GO:0055080 189 0.012
intracellular mrna localization GO:0008298 1 0.012
negative regulation of phosphorus metabolic process GO:0010563 267 0.012
response to testosterone GO:0033574 1 0.012
activation of immune response GO:0002253 114 0.012
Human
positive regulation of chromatin modification GO:1903310 30 0.012
response to uv GO:0009411 73 0.012
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.012
regulation of translation GO:0006417 89 0.011
response to nitrogen compound GO:1901698 184 0.011
regulation of type i interferon mediated signaling pathway GO:0060338 9 0.011
cellular chemical homeostasis GO:0055082 180 0.011
regulation of notch signaling pathway GO:0008593 18 0.011
rostrocaudal neural tube patterning GO:0021903 1 0.011
regulation of peptidase activity GO:0052547 180 0.011
organic acid biosynthetic process GO:0016053 97 0.011
protein n linked glycosylation via asparagine GO:0018279 10 0.011
regulation of protein catabolic process GO:0042176 155 0.011
Human
meiosis i GO:0007127 4 0.011
compound eye development GO:0048749 1 0.011
regulation of response to cytokine stimulus GO:0060759 46 0.011
regulation of vesicle mediated transport GO:0060627 130 0.011
negative regulation of immune response GO:0050777 40 0.011
single organism membrane organization GO:0044802 268 0.011
embryonic camera type eye morphogenesis GO:0048596 2 0.011
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.011
inorganic cation transmembrane transport GO:0098662 194 0.011
cellular macromolecular complex assembly GO:0034622 324 0.010
regulation of small gtpase mediated signal transduction GO:0051056 156 0.010
regulation of cellular component movement GO:0051270 334 0.010
regulation of androgen receptor signaling pathway GO:0060765 18 0.010
Human
response to tumor necrosis factor GO:0034612 76 0.010
small gtpase mediated signal transduction GO:0007264 78 0.010
cellular response to glucocorticoid stimulus GO:0071385 4 0.010

TRIM27 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.336
carbohydrate metabolic disorder DOID:2978 55 0.191
inherited metabolic disorder DOID:655 242 0.191
lysosomal storage disease DOID:3211 47 0.053
congenital disorder of glycosylation DOID:5212 26 0.015
central nervous system disease DOID:331 186 0.013
nervous system disease DOID:863 431 0.013
neuropathy DOID:870 52 0.013
peripheral neuropathy DOID:0060053 12 0.012