Homo sapiens

117 known processes

TSC2

tuberous sclerosis 2

(Aliases: LAM,FLJ43106,TSC4)

TSC2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neural tube formation GO:0001841 3 0.994
Mouse
positive regulation of ras gtpase activity GO:0032320 117 0.989
Fly
small gtpase mediated signal transduction GO:0007264 78 0.988
potassium ion transport GO:0006813 62 0.983
primary neural tube formation GO:0014020 3 0.981
Mouse
female gamete generation GO:0007292 2 0.978
Fly
ras protein signal transduction GO:0007265 73 0.976
tor signaling GO:0031929 39 0.974
Mouse Rat Fly
embryonic morphogenesis GO:0048598 85 0.971
Mouse
morphogenesis of embryonic epithelium GO:0016331 4 0.961
Mouse
regulation of autophagy GO:0010506 52 0.936
Fly
regulation of gtp catabolic process GO:0033124 180 0.933
determination of adult lifespan GO:0008340 2 0.930
Fly
regulation of cell cycle GO:0051726 393 0.930
Rat Fly
positive regulation of autophagy GO:0010508 24 0.929
Fly
purine nucleoside triphosphate catabolic process GO:0009146 392 0.918
gtp catabolic process GO:0006184 237 0.916
oogenesis GO:0048477 2 0.909
Fly
autophagy GO:0006914 88 0.892
Fly
regulation of kinase activity GO:0043549 314 0.884
Mouse Rat
cell development GO:0048468 328 0.879
Fly
transmission of nerve impulse GO:0019226 11 0.874
ribonucleoside triphosphate metabolic process GO:0009199 412 0.857
positive regulation of hydrolase activity GO:0051345 331 0.857
growth GO:0040007 202 0.843
Fly
hippocampus development GO:0021766 1 0.842
limbic system development GO:0021761 3 0.840
monovalent inorganic cation transport GO:0015672 128 0.840
action potential GO:0001508 34 0.837
enteroendocrine cell differentiation GO:0035883 6 0.829
rho protein signal transduction GO:0007266 26 0.828
lipid metabolic process GO:0006629 381 0.826
Fly
tube closure GO:0060606 3 0.820
Mouse
positive regulation of gtpase activity GO:0043547 166 0.820
purine containing compound catabolic process GO:0072523 411 0.814
ribonucleotide catabolic process GO:0009261 405 0.809
positive regulation of gtp catabolic process GO:0033126 166 0.804
regulation of purine nucleotide metabolic process GO:1900542 264 0.799
positive regulation of cell adhesion GO:0045785 84 0.799
positive regulation of catabolic process GO:0009896 310 0.798
organophosphate catabolic process GO:0046434 430 0.798
nucleoside catabolic process GO:0009164 408 0.792
cation transport GO:0006812 331 0.788
guanosine containing compound catabolic process GO:1901069 239 0.779
regulation of rho gtpase activity GO:0032319 66 0.773
nucleotide catabolic process GO:0009166 408 0.746
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.739
tube morphogenesis GO:0035239 95 0.735
Mouse
regulation of gtpase activity GO:0043087 180 0.725
cellular component morphogenesis GO:0032989 314 0.719
regulation of transferase activity GO:0051338 355 0.715
Mouse Rat
regulation of protein kinase activity GO:0045859 289 0.713
Mouse Rat
guanosine containing compound metabolic process GO:1901068 244 0.709
organ morphogenesis GO:0009887 147 0.697
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.697
Mouse Fly
glandular epithelial cell differentiation GO:0002067 6 0.683
renal system development GO:0072001 63 0.682
purine nucleoside catabolic process GO:0006152 398 0.677
regulation of membrane potential GO:0042391 95 0.660
enzyme linked receptor protein signaling pathway GO:0007167 303 0.658
Mouse Fly
gtp metabolic process GO:0046039 239 0.642
cellular response to nitrogen compound GO:1901699 144 0.636
Mouse Fly
ribonucleoside catabolic process GO:0042454 406 0.632
cellular response to hypoxia GO:0071456 51 0.625
Fly
epithelial tube morphogenesis GO:0060562 38 0.613
Mouse
nervous system development GO:0007399 293 0.610
Mouse Fly
regulation of cytoskeleton organization GO:0051493 177 0.607
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.606
glycosyl compound catabolic process GO:1901658 413 0.605
regulation of rho protein signal transduction GO:0035023 79 0.604
metal ion transport GO:0030001 272 0.600
negative regulation of cell growth GO:0030308 83 0.591
Fly
negative regulation of protein metabolic process GO:0051248 391 0.587
Mouse Rat
urogenital system development GO:0001655 65 0.586
negative regulation of developmental process GO:0051093 247 0.581
Fly
neural tube closure GO:0001843 3 0.581
Mouse
regulation of nucleotide catabolic process GO:0030811 205 0.581
nucleoside triphosphate metabolic process GO:0009141 422 0.580
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.575
regulation of cell substrate adhesion GO:0010810 68 0.573
regulation of nucleoside metabolic process GO:0009118 209 0.570
regulation of cellular component biogenesis GO:0044087 281 0.570
Fly
regulation of translation GO:0006417 89 0.563
regulation of purine nucleotide catabolic process GO:0033121 205 0.561
regulation of small gtpase mediated signal transduction GO:0051056 156 0.553
Fly
nuclear transport GO:0051169 179 0.550
Mouse
positive regulation of nucleoside metabolic process GO:0045979 186 0.548
negative regulation of tor signaling GO:0032007 11 0.548
Mouse Rat Fly
response to hypoxia GO:0001666 96 0.535
Mouse Fly
neurological system process GO:0050877 163 0.525
negative regulation of cellular protein metabolic process GO:0032269 353 0.525
Mouse Rat
regulation of insulin receptor signaling pathway GO:0046626 13 0.523
Mouse Fly
regulation of cellular component size GO:0032535 82 0.519
Rat Fly
negative regulation of multicellular organismal process GO:0051241 317 0.517
Fly
circulatory system development GO:0072359 262 0.516
Mouse
positive regulation of rho gtpase activity GO:0032321 56 0.507
nucleoside phosphate catabolic process GO:1901292 412 0.500
anatomical structure formation involved in morphogenesis GO:0048646 284 0.500
Mouse
cellular response to peptide GO:1901653 59 0.498
Mouse Fly
axon ensheathment GO:0008366 6 0.495
regulation of cell differentiation GO:0045595 393 0.493
response to oxygen levels GO:0070482 100 0.493
Mouse Fly
positive regulation of nucleotide catabolic process GO:0030813 185 0.489
cellular response to decreased oxygen levels GO:0036294 51 0.484
Fly
cellular response to endogenous stimulus GO:0071495 336 0.481
Mouse Fly
purine nucleotide catabolic process GO:0006195 405 0.480
regulation of ras gtpase activity GO:0032318 128 0.479
Fly
response to decreased oxygen levels GO:0036293 96 0.475
Mouse Fly
purine ribonucleotide catabolic process GO:0009154 404 0.474
purine ribonucleoside catabolic process GO:0046130 398 0.466
myelination GO:0042552 6 0.458
cilium morphogenesis GO:0060271 75 0.452
cellular response to peptide hormone stimulus GO:0071375 56 0.442
Mouse Fly
reactive oxygen species metabolic process GO:0072593 75 0.441
system process GO:0003008 349 0.406
regulation of reactive oxygen species metabolic process GO:2000377 41 0.400
columnar cuboidal epithelial cell differentiation GO:0002065 14 0.398
actin filament bundle assembly GO:0051017 54 0.395
regulation of cell growth GO:0001558 135 0.395
Fly
response to nutrient levels GO:0031667 81 0.393
Fly
negative regulation of intracellular signal transduction GO:1902532 183 0.384
Mouse Rat Fly
regulation of nucleotide metabolic process GO:0006140 269 0.383
organ growth GO:0035265 12 0.376
Fly
dephosphorylation GO:0016311 209 0.376
negative regulation of phosphorylation GO:0042326 174 0.374
Mouse Rat
cellular response to oxygen levels GO:0071453 55 0.373
Fly
regulation of cell adhesion GO:0030155 166 0.370
positive regulation of cellular component biogenesis GO:0044089 158 0.367
positive regulation of anoikis GO:2000210 4 0.365
negative regulation of developmental growth GO:0048640 10 0.353
Fly
tube development GO:0035295 125 0.353
Mouse
response to peptide GO:1901652 65 0.352
Mouse Fly
purine nucleoside triphosphate metabolic process GO:0009144 412 0.349
regulation of dephosphorylation GO:0035303 96 0.346
response to extracellular stimulus GO:0009991 85 0.341
Fly
generation of neurons GO:0048699 152 0.338
kidney development GO:0001822 53 0.335
multicellular organismal aging GO:0010259 3 0.332
Fly
cell morphogenesis GO:0000902 296 0.332
response to organonitrogen compound GO:0010243 156 0.325
Mouse Fly
macroautophagy GO:0016236 39 0.321
cell substrate adhesion GO:0031589 132 0.313
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.311
cerebral cortex development GO:0021987 10 0.309
actin filament organization GO:0007015 128 0.308
positive regulation of rab gtpase activity GO:0032851 39 0.303
ribosome biogenesis GO:0042254 48 0.297
neuron differentiation GO:0030182 138 0.292
cell junction organization GO:0034330 79 0.289
regulation of rab gtpase activity GO:0032313 39 0.288
cardiac muscle tissue development GO:0048738 39 0.287
positive regulation of cellular catabolic process GO:0031331 284 0.280
response to nitrogen compound GO:1901698 184 0.279
Mouse Fly
single organism membrane organization GO:0044802 268 0.265
Mouse
rab protein signal transduction GO:0032482 4 0.260
protein stabilization GO:0050821 64 0.257
translation GO:0006412 132 0.253
response to oxygen containing compound GO:1901700 369 0.250
Mouse Fly
biological adhesion GO:0022610 331 0.247
response to abiotic stimulus GO:0009628 336 0.247
Mouse Fly
epithelial cell differentiation GO:0030855 141 0.243
posttranscriptional regulation of gene expression GO:0010608 213 0.240
cell matrix adhesion GO:0007160 85 0.240
nucleocytoplasmic transport GO:0006913 176 0.236
Mouse
regulation of phosphatase activity GO:0010921 81 0.235
nuclear export GO:0051168 69 0.234
single organism reproductive process GO:0044702 98 0.231
Fly
regulation of rab protein signal transduction GO:0032483 39 0.230
axon cargo transport GO:0008088 2 0.229
positive regulation of cell junction assembly GO:1901890 11 0.228
positive regulation of cell substrate adhesion GO:0010811 37 0.228
developmental growth GO:0048589 48 0.226
Fly
regulation of growth GO:0040008 165 0.223
Fly
negative regulation of cellular component movement GO:0051271 106 0.221
photoreceptor cell differentiation GO:0046530 2 0.217
morphogenesis of an epithelium GO:0002009 60 0.215
Mouse
negative regulation of cell motility GO:2000146 104 0.213
negative regulation of phosphate metabolic process GO:0045936 267 0.210
Mouse Rat
somatic muscle development GO:0007525 1 0.206
multicellular organismal signaling GO:0035637 34 0.206
cellular response to organonitrogen compound GO:0071417 124 0.205
Mouse Fly
central nervous system development GO:0007417 123 0.204
cell projection morphogenesis GO:0048858 129 0.203
regulation of actin cytoskeleton organization GO:0032956 116 0.203
locomotory behavior GO:0007626 1 0.199
regulation of ras protein signal transduction GO:0046578 155 0.192
Fly
regulation of phosphoprotein phosphatase activity GO:0043666 23 0.192
regulation of anatomical structure size GO:0090066 101 0.191
Rat Fly
specification of symmetry GO:0009799 16 0.190
nucleoside triphosphate catabolic process GO:0009143 394 0.189
pronephros development GO:0048793 2 0.186
microtubule cytoskeleton organization GO:0000226 176 0.185
hexose transport GO:0008645 30 0.184
Mouse
cell projection organization GO:0030030 252 0.182
Rat
positive regulation of phosphorylation GO:0042327 394 0.182
Fly
head development GO:0060322 108 0.181
cell cell junction organization GO:0045216 69 0.178
neural tube development GO:0021915 9 0.175
Mouse
regulation of cell matrix adhesion GO:0001952 42 0.175
positive regulation of cell matrix adhesion GO:0001954 23 0.175
telencephalon development GO:0021537 17 0.173
negative regulation of protein phosphorylation GO:0001933 140 0.168
Mouse Rat
positive regulation of nucleotide metabolic process GO:0045981 230 0.168
rna localization GO:0006403 41 0.168
neurogenesis GO:0022008 169 0.166
positive regulation of glial cell proliferation GO:0060252 2 0.164
regulation of cell morphogenesis GO:0022604 153 0.163
reproductive process GO:0022414 106 0.163
Fly
cell part morphogenesis GO:0032990 137 0.163
cytoplasmic transport GO:0016482 379 0.163
Mouse
heart development GO:0007507 95 0.160
Mouse
tissue morphogenesis GO:0048729 96 0.160
Mouse
negative regulation of cell size GO:0045792 3 0.158
Rat Fly
rna transport GO:0050658 39 0.156
ribonucleoprotein complex biogenesis GO:0022613 116 0.156
glucose import GO:0046323 24 0.152
Mouse
stress fiber assembly GO:0043149 40 0.152
regulation of cellular ketone metabolic process GO:0010565 50 0.150
regulation of cellular response to insulin stimulus GO:1900076 17 0.149
Mouse Fly
cell adhesion GO:0007155 325 0.147
cellular response to oxygen containing compound GO:1901701 276 0.146
Mouse Fly
neuron projection development GO:0031175 106 0.145
regulation of cellular amine metabolic process GO:0033238 11 0.142
positive regulation of cellular component organization GO:0051130 376 0.139
muscle structure development GO:0061061 98 0.137
glucose transport GO:0015758 30 0.136
Mouse
brain development GO:0007420 97 0.136
positive regulation of transferase activity GO:0051347 227 0.135
regulation of actin filament based process GO:0032970 141 0.135
anterior posterior axis specification embryo GO:0008595 2 0.134
protein modification by small protein conjugation GO:0032446 342 0.129
adherens junction organization GO:0034332 36 0.129
carbohydrate transport GO:0008643 37 0.128
Mouse
nitrogen compound transport GO:0071705 191 0.126
regulation of focal adhesion assembly GO:0051893 20 0.126
pallium development GO:0021543 10 0.123
regulation of neuron differentiation GO:0045664 70 0.122
oocyte differentiation GO:0009994 2 0.119
monosaccharide transport GO:0015749 32 0.118
Mouse
cytoskeleton dependent intracellular transport GO:0030705 21 0.117
trachea development GO:0060438 1 0.115
ion transmembrane transport GO:0034220 338 0.114
pattern specification process GO:0007389 43 0.113
regulation of adherens junction organization GO:1903391 21 0.113
negative regulation of peptidyl serine dephosphorylation GO:1902309 1 0.111
epithelial tube formation GO:0072175 5 0.111
Mouse
striated muscle tissue development GO:0014706 59 0.111
actin filament bundle organization GO:0061572 54 0.111
regulation of cell development GO:0060284 161 0.111
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.110
cellular ketone metabolic process GO:0042180 80 0.108
positive regulation of cell proliferation GO:0008284 301 0.107
forebrain development GO:0030900 26 0.106
oocyte development GO:0048599 1 0.105
cell division GO:0051301 168 0.105
cardiac muscle cell differentiation GO:0055007 15 0.103
ribonucleotide biosynthetic process GO:0009260 81 0.102
negative regulation of cellular response to insulin stimulus GO:1900077 8 0.102
Fly
anterior posterior axis specification GO:0009948 2 0.102
regulation of actin filament bundle assembly GO:0032231 36 0.102
cell fate determination GO:0001709 3 0.100
protein dephosphorylation GO:0006470 81 0.099
hindbrain development GO:0030902 3 0.095
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.094
regulation of neurogenesis GO:0050767 82 0.093
response to nutrient GO:0007584 20 0.092
Fly
positive regulation of adherens junction organization GO:1903393 12 0.092
nucleobase containing compound transport GO:0015931 51 0.091
transmembrane transport GO:0055085 399 0.088
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.088
endomembrane system organization GO:0010256 196 0.087
Mouse
signal transduction by phosphorylation GO:0023014 297 0.086
Rat
positive regulation of synaptic transmission GO:0050806 4 0.086
negative regulation of phosphorus metabolic process GO:0010563 267 0.085
Mouse Rat
regulation of potassium ion transport GO:0043266 24 0.084
single organism cellular localization GO:1902580 332 0.084
Mouse
cell morphogenesis involved in differentiation GO:0000904 144 0.082
homeostasis of number of cells GO:0048872 40 0.081
cell junction assembly GO:0034329 67 0.081
muscle cell differentiation GO:0042692 63 0.080
blastoderm segmentation GO:0007350 2 0.080
post embryonic development GO:0009791 2 0.080
Fly
activation of ras gtpase activity GO:0032856 15 0.078
regulation of canonical wnt signaling pathway GO:0060828 88 0.078
multicellular organismal reproductive process GO:0048609 40 0.077
Fly
positive regulation of cellular amine metabolic process GO:0033240 7 0.076
positive regulation of developmental process GO:0051094 314 0.075
positive regulation of protein kinase activity GO:0045860 190 0.074
microtubule organizing center organization GO:0031023 62 0.073
microtubule based process GO:0007017 210 0.073
negative regulation of translation GO:0017148 37 0.073
establishment of nucleus localization GO:0040023 1 0.073
multicellular organism reproduction GO:0032504 42 0.072
Fly
nuclear migration GO:0007097 1 0.071
cellular response to external stimulus GO:0071496 111 0.071
segmentation GO:0035282 4 0.071
regulation of cellular amino acid metabolic process GO:0006521 6 0.070
actin cytoskeleton organization GO:0030036 207 0.070
mitotic cell cycle phase transition GO:0044772 162 0.070
response to starvation GO:0042594 59 0.070
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.067
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.067
negative regulation of apoptotic process GO:0043066 316 0.066
negative regulation of catalytic activity GO:0043086 335 0.066
Mouse Rat
actin filament based process GO:0030029 224 0.066
cell growth GO:0016049 160 0.065
Fly
regulation of meiotic cell cycle GO:0051445 4 0.065
negative regulation of protein kinase activity GO:0006469 98 0.065
Mouse Rat
developmental process involved in reproduction GO:0003006 66 0.065
Fly
mapk cascade GO:0000165 288 0.065
Rat
establishment of rna localization GO:0051236 39 0.064
negative regulation of locomotion GO:0040013 118 0.064
nucleus localization GO:0051647 1 0.064
regulation of mapk cascade GO:0043408 262 0.064
Rat
ensheathment of neurons GO:0007272 6 0.063
regulation of map kinase activity GO:0043405 108 0.063
Rat
regulation of cell projection organization GO:0031344 107 0.062
mitochondrion transport along microtubule GO:0047497 3 0.062
regulation of anatomical structure morphogenesis GO:0022603 286 0.062
rrna export from nucleus GO:0006407 1 0.062
ribonucleoside triphosphate catabolic process GO:0009203 391 0.061
carbohydrate metabolic process GO:0005975 207 0.061
cellular macromolecular complex assembly GO:0034622 324 0.061
multi organism reproductive process GO:0044703 54 0.061
Fly
cellular component disassembly GO:0022411 92 0.061
negative regulation of protein modification process GO:0031400 200 0.060
Mouse Rat
sodium ion transport GO:0006814 61 0.060
mitochondrion organization GO:0007005 156 0.059
neuromuscular junction development GO:0007528 3 0.059
Fly
regulation of nervous system development GO:0051960 88 0.059
Fly
negative regulation of catabolic process GO:0009895 104 0.058
regulation of cellular response to stress GO:0080135 244 0.058
long term memory GO:0007616 2 0.057
cellular amine metabolic process GO:0044106 41 0.056
response to light stimulus GO:0009416 87 0.056
tissue migration GO:0090130 119 0.056
vesicle mediated transport GO:0016192 371 0.053
Mouse Fly
epithelium development GO:0060429 227 0.053
Mouse
endocytosis GO:0006897 159 0.053
Mouse Fly
protein targeting GO:0006605 187 0.053
Mouse
negative regulation of transferase activity GO:0051348 124 0.052
Mouse Rat
amine metabolic process GO:0009308 44 0.052
cytokinesis GO:0000910 96 0.052
negative regulation of growth GO:0045926 97 0.052
Fly
erk1 and erk2 cascade GO:0070371 104 0.051
plasma membrane organization GO:0007009 115 0.051
Mouse
cellular response to nutrient levels GO:0031669 69 0.050
eye photoreceptor cell differentiation GO:0001754 2 0.050
intracellular protein transport GO:0006886 270 0.049
Mouse
nucleic acid transport GO:0050657 39 0.049
regulation of protein catabolic process GO:0042176 155 0.049
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.049
adherens junction assembly GO:0034333 34 0.048
regulation of peptidyl serine dephosphorylation GO:1902308 2 0.048
rrna transport GO:0051029 4 0.048
wnt signaling pathway GO:0016055 156 0.047
Rat
single organism carbohydrate metabolic process GO:0044723 193 0.047
regulation of mitotic cell cycle GO:0007346 189 0.047
negative regulation of cell migration GO:0030336 102 0.047
negative regulation of programmed cell death GO:0043069 321 0.047
cell substrate junction assembly GO:0007044 35 0.046
negative regulation of cellular component organization GO:0051129 235 0.046
Fly
membrane organization GO:0061024 292 0.046
Mouse
cellular response to toxic substance GO:0097237 4 0.045
apoptotic signaling pathway GO:0097190 268 0.045
cytoskeleton dependent cytokinesis GO:0061640 22 0.045
negative regulation of transport GO:0051051 176 0.044
regulation of tor signaling GO:0032006 30 0.044
Mouse Rat Fly
regulation of neuron projection development GO:0010975 57 0.044
regulation of cell diameter GO:0060305 1 0.043
cellular carbohydrate metabolic process GO:0044262 84 0.043
positive regulation of cell differentiation GO:0045597 211 0.043
maintenance of location GO:0051235 112 0.042
regulation of transmembrane transporter activity GO:0022898 74 0.042
cellular response to dna damage stimulus GO:0006974 379 0.041
Fly
regulation of synaptic plasticity GO:0048167 3 0.041
adult locomotory behavior GO:0008344 1 0.040
positive regulation of meiotic cell cycle GO:0051446 2 0.040
mitotic cell cycle process GO:1903047 286 0.040
organelle assembly GO:0070925 176 0.039
cardiocyte differentiation GO:0035051 23 0.039
regulation of proteolysis GO:0030162 293 0.039
mitochondrial respiratory chain complex assembly GO:0033108 23 0.038
cation transmembrane transport GO:0098655 238 0.038
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.038
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.038
regulation of epithelial cell migration GO:0010632 93 0.037
cellular chemical homeostasis GO:0055082 180 0.037
cellular potassium ion transport GO:0071804 60 0.036
reactive oxygen species biosynthetic process GO:1903409 4 0.036
chordate embryonic development GO:0043009 34 0.036
Mouse
regulation of cell junction assembly GO:1901888 29 0.036
respiratory system development GO:0060541 22 0.036
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.035
somatic stem cell maintenance GO:0035019 4 0.035
regulation of cell substrate junction assembly GO:0090109 20 0.035
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.035
positive regulation of gliogenesis GO:0014015 4 0.034
neuron development GO:0048666 113 0.034
mitochondrion distribution GO:0048311 3 0.032
regulation of cell motility GO:2000145 299 0.032
negative regulation of insulin receptor signaling pathway GO:0046627 8 0.032
Fly
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.032
cellular amino acid metabolic process GO:0006520 116 0.032
neuronal stem cell division GO:0036445 1 0.032
synapse organization GO:0050808 14 0.031
Fly
neuron projection morphogenesis GO:0048812 50 0.031
microtubule based movement GO:0007018 32 0.031
positive regulation of mapk cascade GO:0043410 190 0.031
negative regulation of organ growth GO:0046621 5 0.030
Fly
oxidation reduction process GO:0055114 396 0.030
stem cell development GO:0048864 69 0.030
regulation of cell size GO:0008361 19 0.030
Rat Fly
protein ubiquitination GO:0016567 314 0.030
peptidyl lysine modification GO:0018205 144 0.030
tripartite regional subdivision GO:0007351 2 0.029
positive regulation of cell cycle GO:0045787 140 0.029
positive regulation of protein catabolic process GO:0045732 75 0.029
single organism nuclear import GO:1902593 104 0.029
Mouse
innate immune response GO:0045087 178 0.029
cell projection assembly GO:0030031 126 0.029
negative regulation of t cell apoptotic process GO:0070233 4 0.028
potassium ion transmembrane transport GO:0071805 60 0.028
generation of precursor metabolites and energy GO:0006091 68 0.028
memory GO:0007613 3 0.028
determination of left right symmetry GO:0007368 11 0.028
positive regulation of kinase activity GO:0033674 204 0.028
protein localization to plasma membrane GO:0072659 93 0.028
Mouse
visual learning GO:0008542 1 0.028
embryonic epithelial tube formation GO:0001838 4 0.028
Mouse
organelle localization GO:0051640 84 0.028
protein catabolic process GO:0030163 325 0.028
negative regulation of protein maturation GO:1903318 142 0.027
cellular homeostasis GO:0019725 196 0.027
regulation of carbohydrate metabolic process GO:0006109 54 0.027
regulation of protein ubiquitination GO:0031396 95 0.027
cell cycle phase transition GO:0044770 173 0.027
lipid modification GO:0030258 84 0.027
protein maturation GO:0051604 233 0.027
cellular response to starvation GO:0009267 58 0.026
chemical homeostasis GO:0048878 306 0.026
lipid catabolic process GO:0016042 84 0.026
regulation of protein import into nucleus GO:0042306 78 0.026
regulation of locomotion GO:0040012 329 0.026
positive regulation of translation GO:0045727 35 0.026
protein k63 linked deubiquitination GO:0070536 21 0.026
negative regulation of response to extracellular stimulus GO:0032105 5 0.026
male meiosis GO:0007140 1 0.025
cellular macromolecule catabolic process GO:0044265 380 0.025
cell substrate adherens junction assembly GO:0007045 30 0.025
establishment or maintenance of cell polarity GO:0007163 31 0.025
sodium ion transmembrane transport GO:0035725 59 0.025
positive regulation of growth GO:0045927 58 0.025
substantia nigra development GO:0021762 45 0.025
positive regulation of protein phosphorylation GO:0001934 313 0.025
Fly
purine ribonucleoside metabolic process GO:0046128 437 0.025
focal adhesion assembly GO:0048041 30 0.025
long term synaptic potentiation GO:0060291 1 0.025
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.025
cognition GO:0050890 43 0.025
rhythmic behavior GO:0007622 2 0.025
embryonic placenta development GO:0001892 1 0.024
peptidyl tyrosine phosphorylation GO:0018108 170 0.024
cellular protein catabolic process GO:0044257 261 0.024
establishment of organelle localization GO:0051656 59 0.024
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.024
nucleoside phosphate biosynthetic process GO:1901293 109 0.024
regulation of cell cycle process GO:0010564 266 0.024
midbrain development GO:0030901 45 0.024
centrosome organization GO:0051297 58 0.024
protein processing GO:0016485 226 0.024
protein localization to organelle GO:0033365 280 0.024
Mouse
negative regulation of cell cycle GO:0045786 193 0.024
organelle fission GO:0048285 149 0.023
regulation of macroautophagy GO:0016241 19 0.023
negative regulation of hydrolase activity GO:0051346 182 0.023
synaptic transmission GO:0007268 61 0.023
Fly
monocarboxylic acid metabolic process GO:0032787 185 0.023
inorganic ion transmembrane transport GO:0098660 231 0.023
peptidyl tyrosine modification GO:0018212 170 0.023
glucocorticoid catabolic process GO:0006713 1 0.022
microtubule based transport GO:0010970 21 0.022
mitotic cell cycle GO:0000278 326 0.022
cellular response to extracellular stimulus GO:0031668 72 0.022
response to cytokine GO:0034097 232 0.022

TSC2 disease predictions

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 104 0.041
muscular disease DOID:0080000 114 0.041
heart disease DOID:114 68 0.041
cardiomyopathy DOID:0050700 50 0.041
cardiovascular system disease DOID:1287 106 0.041
musculoskeletal system disease DOID:17 223 0.041
muscle tissue disease DOID:66 113 0.041
central nervous system disease DOID:331 186 0.035
nervous system disease DOID:863 431 0.035