Homo sapiens

0 known processes

TUBA4A

tubulin, alpha 4a

(Aliases: FLJ30169,TUBA1,H2-ALPHA)

TUBA4A biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.286
microtubule polymerization GO:0046785 18 0.187
microtubule based process GO:0007017 210 0.175
cellular protein complex assembly GO:0043623 188 0.144
monocarboxylic acid metabolic process GO:0032787 185 0.126
cellular macromolecular complex assembly GO:0034622 324 0.117
taxis GO:0042330 157 0.087
positive regulation of protein polymerization GO:0032273 45 0.084
membrane organization GO:0061024 292 0.083
chemotaxis GO:0006935 157 0.081
mitotic cell cycle GO:0000278 326 0.075
protein polymerization GO:0051258 71 0.071
regulation of cytoskeleton organization GO:0051493 177 0.070
microtubule polymerization or depolymerization GO:0031109 37 0.070
carbohydrate catabolic process GO:0016052 36 0.070
carbohydrate metabolic process GO:0005975 207 0.069
positive regulation of organelle organization GO:0010638 195 0.068
regulation of cellular ketone metabolic process GO:0010565 50 0.068
single organism carbohydrate metabolic process GO:0044723 193 0.067
positive regulation of cytoskeleton organization GO:0051495 83 0.066
negative regulation of cell death GO:0060548 345 0.065
g protein coupled receptor signaling pathway GO:0007186 207 0.064
purine ribonucleoside metabolic process GO:0046128 437 0.062
regulation of microtubule based process GO:0032886 74 0.062
regulation of cellular component biogenesis GO:0044087 281 0.062
microtubule cytoskeleton organization GO:0000226 176 0.060
organelle fission GO:0048285 149 0.055
cell growth GO:0016049 160 0.054
positive regulation of cellular catabolic process GO:0031331 284 0.053
determination of adult lifespan GO:0008340 2 0.052
response to oxygen containing compound GO:1901700 369 0.051
purine nucleoside triphosphate metabolic process GO:0009144 412 0.050
amine metabolic process GO:0009308 44 0.046
regulation of protein complex assembly GO:0043254 147 0.046
cell part morphogenesis GO:0032990 137 0.046
post embryonic development GO:0009791 2 0.045
regulation of cellular amine metabolic process GO:0033238 11 0.045
cell morphogenesis involved in differentiation GO:0000904 144 0.045
salivary gland morphogenesis GO:0007435 4 0.045
cellular protein catabolic process GO:0044257 261 0.043
nucleoside phosphate biosynthetic process GO:1901293 109 0.043
ribonucleotide biosynthetic process GO:0009260 81 0.042
positive regulation of protein complex assembly GO:0031334 86 0.042
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.041
cellular ketone metabolic process GO:0042180 80 0.041
generation of neurons GO:0048699 152 0.040
cell projection morphogenesis GO:0048858 129 0.040
negative regulation of apoptotic process GO:0043066 316 0.039
regulation of cellular amino acid metabolic process GO:0006521 6 0.039
cellular lipid metabolic process GO:0044255 303 0.039
cellular amine metabolic process GO:0044106 41 0.038
positive regulation of gtpase activity GO:0043547 166 0.038
neuron differentiation GO:0030182 138 0.038
ribonucleoside catabolic process GO:0042454 406 0.038
locomotory behavior GO:0007626 1 0.037
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.037
regulation of microtubule cytoskeleton organization GO:0070507 61 0.037
establishment of nucleus localization GO:0040023 1 0.037
purine nucleoside catabolic process GO:0006152 398 0.036
cell morphogenesis GO:0000902 296 0.036
glycosyl compound catabolic process GO:1901658 413 0.035
generation of precursor metabolites and energy GO:0006091 68 0.034
monosaccharide metabolic process GO:0005996 74 0.033
ribonucleoside triphosphate catabolic process GO:0009203 391 0.033
oxidation reduction process GO:0055114 396 0.033
cellular amino acid metabolic process GO:0006520 116 0.032
cell development GO:0048468 328 0.032
adult locomotory behavior GO:0008344 1 0.032
protein localization to membrane GO:0072657 160 0.032
organonitrogen compound biosynthetic process GO:1901566 200 0.032
single organism carbohydrate catabolic process GO:0044724 33 0.032
response to radiation GO:0009314 151 0.032
positive regulation of transport GO:0051050 336 0.032
modification dependent macromolecule catabolic process GO:0043632 212 0.031
purine nucleotide biosynthetic process GO:0006164 84 0.031
spermatid development GO:0007286 4 0.031
positive regulation of nucleotide metabolic process GO:0045981 230 0.031
plasma membrane organization GO:0007009 115 0.031
pyruvate metabolic process GO:0006090 26 0.031
regulation of microtubule polymerization GO:0031113 12 0.031
ras protein signal transduction GO:0007265 73 0.031
organ morphogenesis GO:0009887 147 0.030
lipid metabolic process GO:0006629 381 0.030
positive regulation of cellular component biogenesis GO:0044089 158 0.030
glycolytic process GO:0006096 17 0.030
organelle assembly GO:0070925 176 0.029
protein ubiquitination GO:0016567 314 0.029
cell projection organization GO:0030030 252 0.029
regulation of mapk cascade GO:0043408 262 0.028
negative regulation of phosphate metabolic process GO:0045936 267 0.028
neuron development GO:0048666 113 0.028
nucleoside triphosphate metabolic process GO:0009141 422 0.028
cellular response to oxygen containing compound GO:1901701 276 0.028
ribonucleotide catabolic process GO:0009261 405 0.028
negative regulation of catalytic activity GO:0043086 335 0.028
protein modification by small protein conjugation GO:0032446 342 0.027
response to hormone GO:0009725 175 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.027
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.027
regulation of proteolysis GO:0030162 293 0.027
neuron projection development GO:0031175 106 0.026
anatomical structure formation involved in morphogenesis GO:0048646 284 0.026
negative regulation of cell growth GO:0030308 83 0.026
positive regulation of catabolic process GO:0009896 310 0.026
response to organic cyclic compound GO:0014070 204 0.026
segmentation GO:0035282 4 0.026
establishment of protein localization to membrane GO:0090150 121 0.026
organophosphate biosynthetic process GO:0090407 163 0.026
calcium ion transmembrane transport GO:0070588 76 0.026
negative regulation of phosphorylation GO:0042326 174 0.026
hexose metabolic process GO:0019318 55 0.025
ribose phosphate biosynthetic process GO:0046390 82 0.025
negative regulation of programmed cell death GO:0043069 321 0.025
meiosis i GO:0007127 4 0.025
response to abiotic stimulus GO:0009628 336 0.025
small molecule biosynthetic process GO:0044283 157 0.025
positive regulation of cellular component organization GO:0051130 376 0.025
regulation of cellular component movement GO:0051270 334 0.024
mapk cascade GO:0000165 288 0.024
regulation of gtp catabolic process GO:0033124 180 0.024
response to other organism GO:0051707 261 0.024
hemopoiesis GO:0030097 180 0.024
ubiquitin dependent protein catabolic process GO:0006511 206 0.024
cation transmembrane transport GO:0098655 238 0.024
multicellular organismal aging GO:0010259 3 0.023
signal transduction by phosphorylation GO:0023014 297 0.023
response to cytokine GO:0034097 232 0.023
secretion by cell GO:0032940 226 0.023
regulation of kinase activity GO:0043549 314 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.022
carbohydrate derivative biosynthetic process GO:1901137 207 0.022
response to drug GO:0042493 81 0.022
epithelium migration GO:0090132 119 0.022
mitotic cell cycle process GO:1903047 286 0.022
positive regulation of kinase activity GO:0033674 204 0.022
regulation of cell activation GO:0050865 125 0.022
purine containing compound catabolic process GO:0072523 411 0.022
nervous system development GO:0007399 293 0.022
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.021
modification dependent protein catabolic process GO:0019941 209 0.021
neurogenesis GO:0022008 169 0.021
ribonucleoside monophosphate metabolic process GO:0009161 187 0.021
regulation of synaptic plasticity GO:0048167 3 0.021
negative regulation of cell proliferation GO:0008285 228 0.021
protein processing GO:0016485 226 0.021
replicative cell aging GO:0001302 3 0.021
regulation of cell cycle process GO:0010564 266 0.021
mitochondrion organization GO:0007005 156 0.021
atp metabolic process GO:0046034 176 0.021
positive regulation of cellular component movement GO:0051272 181 0.021
cellular macromolecule catabolic process GO:0044265 380 0.021
ameboidal type cell migration GO:0001667 135 0.021
positive regulation of immune system process GO:0002684 283 0.021
immune response GO:0006955 307 0.020
negative regulation of growth GO:0045926 97 0.020
axon cargo transport GO:0008088 2 0.020
nucleus localization GO:0051647 1 0.020
protein catabolic process GO:0030163 325 0.020
meiotic chromosome segregation GO:0045132 4 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.020
positive regulation of cell cycle GO:0045787 140 0.020
head development GO:0060322 108 0.020
apoptotic signaling pathway GO:0097190 268 0.020
actin filament based process GO:0030029 224 0.019
intracellular protein transport GO:0006886 270 0.019
somatic muscle development GO:0007525 1 0.019
purine ribonucleotide biosynthetic process GO:0009152 79 0.019
response to biotic stimulus GO:0009607 276 0.019
stress activated protein kinase signaling cascade GO:0031098 94 0.019
cellular response to dna damage stimulus GO:0006974 379 0.019
regulation of cell growth GO:0001558 135 0.019
positive regulation of synaptic transmission GO:0050806 4 0.019
negative regulation of cellular protein metabolic process GO:0032269 353 0.019
covalent chromatin modification GO:0016569 254 0.019
regulation of neural precursor cell proliferation GO:2000177 4 0.019
behavior GO:0007610 112 0.019
purine containing compound biosynthetic process GO:0072522 88 0.019
guanosine containing compound metabolic process GO:1901068 244 0.019
positive regulation of cellular amine metabolic process GO:0033240 7 0.019
organophosphate catabolic process GO:0046434 430 0.019
endomembrane system organization GO:0010256 196 0.018
positive regulation of cell proliferation GO:0008284 301 0.018
apoptotic mitochondrial changes GO:0008637 57 0.018
positive regulation of hydrolase activity GO:0051345 331 0.018
cardiac muscle cell contraction GO:0086003 4 0.018
oogenesis GO:0048477 2 0.018
maintenance of location GO:0051235 112 0.018
protein polyubiquitination GO:0000209 110 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.018
single organism cellular localization GO:1902580 332 0.018
cardiac muscle contraction GO:0060048 34 0.018
cerebral cortex cell migration GO:0021795 3 0.018
regeneration GO:0031099 4 0.018
regulation of transferase activity GO:0051338 355 0.018
microtubule anchoring GO:0034453 24 0.018
nucleotide biosynthetic process GO:0009165 109 0.018
positive regulation of cell differentiation GO:0045597 211 0.018
mitotic nuclear division GO:0007067 119 0.018
chromatin organization GO:0006325 351 0.017
negative regulation of cell cycle process GO:0010948 121 0.017
nucleotide catabolic process GO:0009166 408 0.017
organic acid biosynthetic process GO:0016053 97 0.017
cytokine production GO:0001816 247 0.017
enzyme linked receptor protein signaling pathway GO:0007167 303 0.017
regulation of protein catabolic process GO:0042176 155 0.017
purine nucleoside monophosphate metabolic process GO:0009126 186 0.017
cellular carbohydrate metabolic process GO:0044262 84 0.017
nucleoside monophosphate metabolic process GO:0009123 191 0.017
single organism membrane organization GO:0044802 268 0.017
purine nucleoside monophosphate catabolic process GO:0009128 158 0.017
glucose metabolic process GO:0006006 45 0.017
response to fungus GO:0009620 4 0.017
response to external biotic stimulus GO:0043207 261 0.017
coenzyme metabolic process GO:0006732 65 0.017
muscle system process GO:0003012 81 0.016
carbohydrate biosynthetic process GO:0016051 42 0.016
positive regulation of protein kinase activity GO:0045860 190 0.016
nuclear division GO:0000280 128 0.016
blastoderm segmentation GO:0007350 2 0.016
microtubule nucleation GO:0007020 6 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.016
regulation of cellular protein catabolic process GO:1903362 96 0.016
response to light stimulus GO:0009416 87 0.016
cell fate determination GO:0001709 3 0.016
growth GO:0040007 202 0.016
negative regulation of organelle organization GO:0010639 126 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.016
hippocampus development GO:0021766 1 0.016
regulation of protein maturation GO:1903317 150 0.016
cellular response to extracellular stimulus GO:0031668 72 0.016
gtp metabolic process GO:0046039 239 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
sulfur compound catabolic process GO:0044273 8 0.016
regulation of protein processing GO:0070613 150 0.016
regulation of cytoplasmic transport GO:1903649 149 0.016
fatty acid metabolic process GO:0006631 115 0.015
regulation of immune response GO:0050776 201 0.015
response to axon injury GO:0048678 1 0.015
myoblast fusion GO:0007520 1 0.015
regulation of meiotic cell cycle GO:0051445 4 0.015
cellular response to endogenous stimulus GO:0071495 336 0.015
positive regulation of phosphorylation GO:0042327 394 0.015
cytokinesis GO:0000910 96 0.015
protein maturation GO:0051604 233 0.015
regulation of locomotion GO:0040012 329 0.015
regulation of leukocyte activation GO:0002694 115 0.015
positive regulation of proteolysis GO:0045862 142 0.014
sequestering of calcium ion GO:0051208 17 0.014
cellular ion homeostasis GO:0006873 168 0.014
blood circulation GO:0008015 113 0.014
syncytium formation by plasma membrane fusion GO:0000768 2 0.014
system process GO:0003008 349 0.014
sequestering of metal ion GO:0051238 24 0.014
cell activation GO:0001775 213 0.014
negative regulation of multicellular organismal process GO:0051241 317 0.014
tissue homeostasis GO:0001894 63 0.014
negative regulation of catabolic process GO:0009895 104 0.014
regulation of rho protein signal transduction GO:0035023 79 0.014
innate immune response GO:0045087 178 0.014
regulation of growth GO:0040008 165 0.014
regulation of protein kinase activity GO:0045859 289 0.014
cell cycle checkpoint GO:0000075 117 0.014
memory GO:0007613 3 0.014
regulation of homeostatic process GO:0032844 121 0.014
positive regulation of transferase activity GO:0051347 227 0.014
regulation of ras gtpase activity GO:0032318 128 0.014
cellular response to lipid GO:0071396 127 0.014
chromosome segregation GO:0007059 114 0.014
positive regulation of mapk cascade GO:0043410 190 0.014
oocyte development GO:0048599 1 0.014
cell projection assembly GO:0030031 126 0.014
axon development GO:0061564 34 0.014
stress activated mapk cascade GO:0051403 93 0.014
regulation of cellular response to stress GO:0080135 244 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.014
engulfment of apoptotic cell GO:0043652 2 0.014
regulation of anatomical structure morphogenesis GO:0022603 286 0.013
negative regulation of protein metabolic process GO:0051248 391 0.013
cellular response to external stimulus GO:0071496 111 0.013
peripheral nervous system development GO:0007422 2 0.013
nucleoside catabolic process GO:0009164 408 0.013
sex determination GO:0007530 3 0.013
carboxylic acid biosynthetic process GO:0046394 97 0.013
regulation of t cell activation GO:0050863 77 0.013
positive regulation of protein catabolic process GO:0045732 75 0.013
cofactor biosynthetic process GO:0051188 31 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
regulation of protein ubiquitination GO:0031396 95 0.013
regulation of map kinase activity GO:0043405 108 0.013
limbic system development GO:0021761 3 0.013
glycoprotein metabolic process GO:0009100 110 0.013
negative regulation of protein modification process GO:0031400 200 0.013
negative regulation of apoptotic signaling pathway GO:2001234 97 0.013
jnk cascade GO:0007254 80 0.013
cellular response to hormone stimulus GO:0032870 125 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
reactive nitrogen species metabolic process GO:2001057 3 0.013
negative regulation of cell cycle phase transition GO:1901988 89 0.013
microtubule bundle formation GO:0001578 15 0.013
negative regulation of protein maturation GO:1903318 142 0.013
regulation of purine nucleotide catabolic process GO:0033121 205 0.013
thymus development GO:0048538 3 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.013
muscle cell cellular homeostasis GO:0046716 3 0.013
forebrain generation of neurons GO:0021872 3 0.013
negative regulation of cell cycle GO:0045786 193 0.013
actin cytoskeleton organization GO:0030036 207 0.013
t cell differentiation in thymus GO:0033077 4 0.013
dephosphorylation GO:0016311 209 0.012
regulation of meiosis GO:0040020 3 0.012
cell cell signaling GO:0007267 155 0.012
small gtpase mediated signal transduction GO:0007264 78 0.012
regulation of small gtpase mediated signal transduction GO:0051056 156 0.012
reciprocal meiotic recombination GO:0007131 4 0.012
ribonucleoside triphosphate metabolic process GO:0009199 412 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
regulation of ras protein signal transduction GO:0046578 155 0.012
embryonic placenta development GO:0001892 1 0.012
muscle contraction GO:0006936 73 0.012
forebrain neuron differentiation GO:0021879 3 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
regulation of actin cytoskeleton organization GO:0032956 116 0.012
endocytosis GO:0006897 159 0.012
leukocyte differentiation GO:0002521 98 0.012
actin polymerization or depolymerization GO:0008154 56 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
spindle organization GO:0007051 53 0.012
neuromuscular junction development GO:0007528 3 0.012
regulation of ion homeostasis GO:2000021 73 0.012
calcium ion transport GO:0006816 147 0.012
nucleoside biosynthetic process GO:0009163 26 0.012
tissue regeneration GO:0042246 3 0.012
defense response GO:0006952 315 0.012
angiogenesis GO:0001525 147 0.012
rna interference GO:0016246 4 0.012
positive regulation of nucleotide catabolic process GO:0030813 185 0.012
response to growth factor GO:0070848 205 0.012
cellular response to growth factor stimulus GO:0071363 197 0.012
dna conformation change GO:0071103 113 0.012
anterior posterior axis specification GO:0009948 2 0.012
vasculature development GO:0001944 181 0.012
regulation of ion transmembrane transporter activity GO:0032412 72 0.012
negative regulation of mitotic cell cycle GO:0045930 102 0.012
negative regulation of protein processing GO:0010955 142 0.012
response to wounding GO:0009611 168 0.012
protein oligomerization GO:0051259 173 0.012
microtubule organizing center organization GO:0031023 62 0.011
anatomical structure homeostasis GO:0060249 100 0.011
visual behavior GO:0007632 2 0.011
negative regulation of cellular component organization GO:0051129 235 0.011
positive regulation of ras gtpase activity GO:0032320 117 0.011
intracellular mrna localization GO:0008298 1 0.011
regulation of cellular component size GO:0032535 82 0.011
tissue migration GO:0090130 119 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.011
regulation of cell cycle phase transition GO:1901987 126 0.011
negative regulation of cellular catabolic process GO:0031330 83 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
purine ribonucleoside biosynthetic process GO:0046129 23 0.011
transmembrane transport GO:0055085 399 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
protein localization to organelle GO:0033365 280 0.011
striated muscle myosin thick filament assembly GO:0071688 2 0.011
peptidyl lysine modification GO:0018205 144 0.011
regulation of cell migration GO:0030334 289 0.011
purine ribonucleoside catabolic process GO:0046130 398 0.011
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.011
regulation of ion transport GO:0043269 189 0.011
cranial nerve development GO:0021545 4 0.011
anterograde axon cargo transport GO:0008089 1 0.011
regulation of cell projection organization GO:0031344 107 0.011
negative regulation of hydrolase activity GO:0051346 182 0.011
nucleoside triphosphate catabolic process GO:0009143 394 0.011
positive regulation of protein ubiquitination GO:0031398 53 0.011
positive regulation of protein phosphorylation GO:0001934 313 0.011
regulation of growth rate GO:0040009 1 0.011
nitrogen compound transport GO:0071705 191 0.011
i kappab kinase nf kappab signaling GO:0007249 166 0.011
myeloid cell differentiation GO:0030099 117 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
histone modification GO:0016570 251 0.011
long chain fatty acid metabolic process GO:0001676 30 0.010
lymphocyte proliferation GO:0046651 70 0.010
neurological system process GO:0050877 163 0.010
negative regulation of transferase activity GO:0051348 124 0.010
regulation of response to external stimulus GO:0032101 222 0.010
regulation of lymphocyte activation GO:0051249 103 0.010
neuron fate commitment GO:0048663 2 0.010
regulation of chromosome organization GO:0033044 103 0.010
monocarboxylic acid biosynthetic process GO:0072330 67 0.010
phospholipid metabolic process GO:0006644 99 0.010
positive regulation of gtp catabolic process GO:0033126 166 0.010
regulation of cell motility GO:2000145 299 0.010
cellular response to nutrient levels GO:0031669 69 0.010
regulation of anatomical structure size GO:0090066 101 0.010
tripartite regional subdivision GO:0007351 2 0.010
spermatid differentiation GO:0048515 4 0.010
reactive oxygen species metabolic process GO:0072593 75 0.010
positive regulation of cell death GO:0010942 263 0.010
positive regulation of lymphocyte activation GO:0051251 73 0.010
regulation of actin filament based process GO:0032970 141 0.010

TUBA4A disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.017
central nervous system disease DOID:331 186 0.017
nervous system disease DOID:863 431 0.017
disease of metabolism DOID:0014667 295 0.015
sensory system disease DOID:0050155 203 0.014
immune system disease DOID:2914 155 0.014
muscular disease DOID:0080000 114 0.014
muscle tissue disease DOID:66 113 0.014
disease of cellular proliferation DOID:14566 174 0.013
cancer DOID:162 167 0.012
eye and adnexa disease DOID:1492 150 0.012
acquired metabolic disease DOID:0060158 58 0.011