|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.885
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.557
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.520
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.445
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.441
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.428
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.405
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.393
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.392
|
Mouse |
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.380
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.353
|
|
|
|
peptidyl lysine methylation
|
GO:0018022 |
37 |
0.349
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.337
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.331
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.321
|
|
|
|
regulation of signal transduction by p53 class mediator
|
GO:1901796 |
26 |
0.298
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.276
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.267
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.263
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.261
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.250
|
Mouse Worm Fly |
|
|
histone methylation
|
GO:0016571 |
60 |
0.245
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.242
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.239
|
|
|
|
protein methylation
|
GO:0006479 |
74 |
0.232
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.229
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.223
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.221
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.217
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.213
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.209
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.207
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.195
|
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.190
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.176
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.173
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.167
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.166
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.166
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.160
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.155
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.152
|
|
|
|
dna packaging
|
GO:0006323 |
77 |
0.147
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.146
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.145
|
Human Mouse |
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.144
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.144
|
Rat |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.143
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.141
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.137
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.134
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.131
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
15 |
0.130
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.125
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.124
|
Human Mouse Worm Fly |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.122
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.121
|
Rat |
|
|
connective tissue development
|
GO:0061448 |
39 |
0.120
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.119
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.118
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.117
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.116
|
Mouse Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.115
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.114
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.112
|
Worm Fly |
|
|
skeletal system morphogenesis
|
GO:0048705 |
24 |
0.112
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.110
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.109
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.109
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.108
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.108
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.107
|
Rat |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.106
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.105
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.105
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.104
|
Rat |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.102
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.102
|
Mouse |
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.102
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.100
|
Worm Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.098
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.094
|
|
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.094
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.092
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.092
|
Mouse Rat |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.091
|
Human |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.090
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.089
|
Rat |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.089
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.088
|
|
|
|
negative regulation of embryonic development
|
GO:0045992 |
4 |
0.087
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.087
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.087
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.086
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.083
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.082
|
|
|
|
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation
|
GO:0044338 |
2 |
0.082
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.082
|
|
|
|
positive regulation of epithelial cell proliferation involved in wound healing
|
GO:0060054 |
3 |
0.082
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.081
|
Mouse Worm Fly |
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.080
|
|
|
|
canonical wnt signaling pathway involved in osteoblast differentiation
|
GO:0044339 |
2 |
0.080
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.080
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.080
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.079
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.078
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.076
|
|
|
|
chromosome condensation
|
GO:0030261 |
15 |
0.075
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.075
|
Human |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.074
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.072
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.070
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.070
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.069
|
|
|
|
negative regulation of gastrulation
|
GO:2000542 |
4 |
0.069
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.068
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.068
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.068
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.067
|
Human |
|
|
peptidyl lysine monomethylation
|
GO:0018026 |
4 |
0.067
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.066
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.066
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.065
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.064
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.063
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.063
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.063
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.063
|
Human |
|
|
forelimb morphogenesis
|
GO:0035136 |
4 |
0.062
|
Mouse |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.061
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.061
|
Worm Fly |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.061
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.060
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.059
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.059
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.059
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.058
|
|
|
|
wnt signaling pathway calcium modulating pathway
|
GO:0007223 |
2 |
0.058
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.057
|
Rat |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.056
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.056
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.055
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.055
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.054
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.054
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.053
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.053
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.053
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.053
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.053
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.053
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.053
|
|
|
|
embryonic forelimb morphogenesis
|
GO:0035115 |
4 |
0.052
|
Mouse |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.052
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.052
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.052
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.052
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.052
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.052
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.052
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.052
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.051
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.050
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.050
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.050
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.049
|
Mouse |
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.049
|
|
|
|
embryonic skeletal joint development
|
GO:0072498 |
2 |
0.049
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.049
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.046
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.046
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.045
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.045
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.045
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.045
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.045
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.044
|
Human |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.044
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.044
|
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.043
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.043
|
Worm Fly |
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
9 |
0.043
|
|
|
|
extraocular skeletal muscle development
|
GO:0002074 |
1 |
0.043
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.043
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.043
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.043
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.043
|
|
|
|
soft palate development
|
GO:0060023 |
3 |
0.042
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.042
|
|
|
|
detection of mechanical stimulus
|
GO:0050982 |
4 |
0.042
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.042
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.042
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.042
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.042
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.042
|
|
|
|
system process
|
GO:0003008 |
349 |
0.041
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.041
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.041
|
Mouse Rat |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.041
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.041
|
Mouse |
|
|
embryonic skeletal system development
|
GO:0048706 |
13 |
0.041
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.041
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.041
|
Human Mouse |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.040
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.040
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.040
|
Human |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.039
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.039
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.039
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.039
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.039
|
|
|
|
cartilage condensation
|
GO:0001502 |
1 |
0.038
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.038
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.038
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.038
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.038
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.038
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.037
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.037
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.037
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.037
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.037
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.037
|
Mouse |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.037
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.037
|
|
|
|
embryonic camera type eye morphogenesis
|
GO:0048596 |
2 |
0.037
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.036
|
|
|
|
embryonic skeletal joint morphogenesis
|
GO:0060272 |
2 |
0.036
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.036
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.036
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.036
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.035
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.035
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.035
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.035
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.035
|
|
|
|
negative regulation of cell fate commitment
|
GO:0010454 |
3 |
0.035
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.034
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.034
|
Mouse |
|
|
response to wounding
|
GO:0009611 |
168 |
0.034
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.034
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.034
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.034
|
Human Mouse Fly |
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.034
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.034
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.034
|
Worm Fly |
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.034
|
Mouse |
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.034
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.033
|
|
|
|
non canonical wnt signaling pathway via mapk cascade
|
GO:0038030 |
4 |
0.033
|
|
|
|
extracellular structure organization
|
GO:0043062 |
41 |
0.033
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.033
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.033
|
|
|
|
positive regulation of insulin like growth factor receptor signaling pathway
|
GO:0043568 |
4 |
0.032
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.032
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.032
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.032
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.032
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.032
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.032
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.032
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.031
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.031
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.031
|
|
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.031
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.031
|
|
|
|
cartilage development involved in endochondral bone morphogenesis
|
GO:0060351 |
2 |
0.031
|
|
|
|
growth
|
GO:0040007 |
202 |
0.031
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.030
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.030
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.030
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.030
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.030
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.030
|
|
|
|
specification of organ identity
|
GO:0010092 |
3 |
0.030
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.030
|
|
|
|
hematopoietic stem cell differentiation
|
GO:0060218 |
4 |
0.029
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.029
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.029
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
41 |
0.029
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.029
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.029
|
Mouse |
|
|
taxis
|
GO:0042330 |
157 |
0.029
|
|
|
|
negative regulation of cell fate specification
|
GO:0009996 |
3 |
0.029
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.029
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.029
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.029
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.029
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.029
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.029
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.029
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.029
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
16 |
0.029
|
Mouse |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.029
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.029
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.028
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.028
|
Mouse |
|
|
membrane organization
|
GO:0061024 |
292 |
0.028
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.028
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.028
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.028
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.028
|
Human |
|
|
startle response
|
GO:0001964 |
3 |
0.028
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.028
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.027
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.027
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.027
|
|
|
|
regulation of sodium dependent phosphate transport
|
GO:2000118 |
2 |
0.027
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.027
|
|
|
|
positive regulation of keratinocyte migration
|
GO:0051549 |
4 |
0.027
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.027
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.027
|
Human Mouse Fly |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.027
|
Human Mouse |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.027
|
|
|
|
head development
|
GO:0060322 |
108 |
0.026
|
Human |
|
|
hindbrain development
|
GO:0030902 |
3 |
0.026
|
Human |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.026
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.026
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.026
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.026
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.026
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.026
|
|
|
|
proteoglycan metabolic process
|
GO:0006029 |
29 |
0.026
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.026
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.026
|
Human |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.026
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.026
|
|
|
|
brain morphogenesis
|
GO:0048854 |
1 |
0.026
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.026
|
Mouse |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.026
|
|
|
|
cardiac right ventricle morphogenesis
|
GO:0003215 |
3 |
0.025
|
Human |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.025
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.025
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.025
|
Mouse Fly |
|
|
gland development
|
GO:0048732 |
48 |
0.025
|
Fly |
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.025
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.025
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.025
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.025
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.024
|
Human Mouse Fly |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.024
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.024
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.024
|
Mouse Rat |
|
|
cell aggregation
|
GO:0098743 |
1 |
0.024
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.024
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.024
|
Worm |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.024
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.024
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.024
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.024
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.023
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.023
|
Mouse Fly |
|
|
embryo development
|
GO:0009790 |
123 |
0.023
|
|
|
|
histone h4 k20 methylation
|
GO:0034770 |
1 |
0.023
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.023
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.023
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.023
|
|
|
|
cardiac cell fate determination
|
GO:0060913 |
3 |
0.023
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
57 |
0.023
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.023
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.023
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.023
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.023
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.022
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.022
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.022
|
Mouse |
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.022
|
|
|
|
appendage development
|
GO:0048736 |
23 |
0.022
|
Mouse |
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.022
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.022
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.022
|
|
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.022
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.022
|
Human |
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.022
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.022
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.022
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.022
|
Human |
|
|
behavior
|
GO:0007610 |
112 |
0.022
|
Worm |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.021
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.021
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.021
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.021
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.021
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.021
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.021
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.021
|
|
|
|
negative regulation of monocyte differentiation
|
GO:0045656 |
3 |
0.021
|
|
|
|
embryonic digestive tract morphogenesis
|
GO:0048557 |
2 |
0.021
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.021
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.021
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.021
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.021
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.021
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.021
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.021
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.021
|
Mouse |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.021
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.021
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.021
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.020
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.020
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.020
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.020
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.020
|
Human |
|
|
chondrocyte development
|
GO:0002063 |
1 |
0.020
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.020
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.020
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.020
|
|
|
|
hormone metabolic process
|
GO:0042445 |
61 |
0.020
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.020
|
|
|
|
positive regulation of odontogenesis
|
GO:0042482 |
3 |
0.020
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.020
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.020
|
|
|
|
sex determination
|
GO:0007530 |
3 |
0.020
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.020
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.020
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.020
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.020
|
|
|
|
embryonic camera type eye formation
|
GO:0060900 |
2 |
0.020
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.020
|
|
|
|
odontogenesis
|
GO:0042476 |
25 |
0.020
|
Rat |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.020
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.020
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.020
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.020
|
|
|
|
forebrain regionalization
|
GO:0021871 |
3 |
0.020
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.019
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.019
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.019
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.019
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.019
|
|
|
|
negative regulation of ectodermal cell fate specification
|
GO:0042666 |
1 |
0.019
|
|
|
|
detection of mechanical stimulus involved in sensory perception
|
GO:0050974 |
1 |
0.019
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.019
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.019
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.019
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.019
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.019
|
|
|
|
outflow tract septum morphogenesis
|
GO:0003148 |
4 |
0.019
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.019
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.019
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.019
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.019
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.019
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.019
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.019
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.019
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.019
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.019
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.019
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.019
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.019
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.019
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.019
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.019
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.019
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.019
|
Mouse |
|
|
response to other organism
|
GO:0051707 |
261 |
0.019
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.019
|
Fly |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.019
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.018
|
|
|
|
menstrual cycle phase
|
GO:0022601 |
2 |
0.018
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.018
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.018
|
|
|
|
prostate gland development
|
GO:0030850 |
3 |
0.018
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.018
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.018
|
|
|
|
cell fate commitment involved in pattern specification
|
GO:0060581 |
1 |
0.018
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.018
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.018
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.018
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.018
|
Mouse |
|
|
anion transport
|
GO:0006820 |
161 |
0.018
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.018
|
|
|
|
regulation of odontogenesis
|
GO:0042481 |
4 |
0.018
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.018
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.018
|
Mouse |
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.018
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
2 |
0.018
|
Worm Fly |
|
|
sensory perception
|
GO:0007600 |
103 |
0.018
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.018
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.018
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.018
|
|
|
|
neuroendocrine cell differentiation
|
GO:0061101 |
2 |
0.018
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.017
|
|
