Homo sapiens

62 known processes

U2AF2

U2 small nuclear RNA auxiliary factor 2

(Aliases: U2AF65)

U2AF2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of mrna splicing via spliceosome GO:0048024 32 1.000
mrna splicing via spliceosome GO:0000398 89 1.000
regulation of rna splicing GO:0043484 62 1.000
rna splicing via transesterification reactions GO:0000375 90 1.000
regulation of mrna processing GO:0050684 48 1.000
mrna metabolic process GO:0016071 175 1.000
rna splicing GO:0008380 131 1.000
rna processing GO:0006396 255 1.000
regulation of alternative mrna splicing via spliceosome GO:0000381 22 1.000
Fly
regulation of mrna metabolic process GO:1903311 53 0.999
mrna processing GO:0006397 133 0.998
alternative mrna splicing via spliceosome GO:0000380 27 0.993
Fly
rna stabilization GO:0043489 18 0.991
ribonucleoprotein complex biogenesis GO:0022613 116 0.989
regulation of meiotic cell cycle GO:0051445 4 0.985
Worm
negative regulation of rna splicing GO:0033119 15 0.974
ribonucleoprotein complex subunit organization GO:0071826 81 0.952
oogenesis GO:0048477 2 0.951
regulation of cell cycle GO:0051726 393 0.928
Worm
negative regulation of mrna metabolic process GO:1903312 15 0.879
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.837
ribonucleoprotein complex assembly GO:0022618 78 0.837
positive regulation of nucleobase containing compound transport GO:0032241 1 0.774
Fly
negative regulation of mrna splicing via spliceosome GO:0048025 11 0.764
female gamete generation GO:0007292 2 0.757
spliceosomal complex assembly GO:0000245 17 0.736
positive regulation of developmental process GO:0051094 314 0.724
mrna splice site selection GO:0006376 7 0.614
regulation of cell differentiation GO:0045595 393 0.599
meiotic nuclear division GO:0007126 10 0.599
Worm
posttranscriptional regulation of gene expression GO:0010608 213 0.513
negative regulation of mrna processing GO:0050686 12 0.496
ncrna metabolic process GO:0034660 108 0.465
positive regulation of programmed cell death GO:0043068 249 0.463
positive regulation of cell differentiation GO:0045597 211 0.399
cellular response to dna damage stimulus GO:0006974 379 0.398
positive regulation of cell death GO:0010942 263 0.391
mrna stabilization GO:0048255 18 0.359
lipid metabolic process GO:0006629 381 0.354
regulation of cell division GO:0051302 116 0.350
Worm
nuclear transcribed mrna catabolic process GO:0000956 48 0.342
meiotic cell cycle GO:0051321 13 0.337
Worm
behavior GO:0007610 112 0.325
negative regulation of cellular protein metabolic process GO:0032269 353 0.312
regulation of cell cycle process GO:0010564 266 0.296
Worm
positive regulation of apoptotic process GO:0043065 246 0.291
rna catabolic process GO:0006401 71 0.281
lipid biosynthetic process GO:0008610 177 0.261
reproductive process GO:0022414 106 0.259
Worm
cellular macromolecule catabolic process GO:0044265 380 0.235
regulation of mrna stability GO:0043488 23 0.226
cell development GO:0048468 328 0.226
Worm
regulation of meiosis GO:0040020 3 0.214
Worm
multicellular organism reproduction GO:0032504 42 0.202
Worm
cell fate determination GO:0001709 3 0.202
developmental process involved in reproduction GO:0003006 66 0.195
Worm
plasma lipoprotein particle clearance GO:0034381 16 0.193
nucleocytoplasmic transport GO:0006913 176 0.174
Fly
regulation of nuclear division GO:0051783 65 0.159
Worm
positive regulation of gliogenesis GO:0014015 4 0.156
cell division GO:0051301 168 0.155
Worm
regulation of astrocyte differentiation GO:0048710 3 0.145
positive regulation of intracellular transport GO:0032388 104 0.141
Fly
cellular macromolecular complex assembly GO:0034622 324 0.140
muscle structure development GO:0061061 98 0.139
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.131
gonad development GO:0008406 34 0.129
Worm
hemidesmosome assembly GO:0031581 5 0.124
mitotic cell cycle process GO:1903047 286 0.117
Fly
sex determination GO:0007530 3 0.114
Worm
spermatid development GO:0007286 4 0.108
regulation of rna stability GO:0043487 23 0.107
embryo development GO:0009790 123 0.106
Worm
developmental growth GO:0048589 48 0.103
Worm
growth GO:0040007 202 0.101
Worm
neuron differentiation GO:0030182 138 0.093
cellular process involved in reproduction in multicellular organism GO:0022412 15 0.088
Worm
negative regulation of translation GO:0017148 37 0.086
cell junction organization GO:0034330 79 0.081
regulation of actin filament based process GO:0032970 141 0.081
posttranscriptional gene silencing by rna GO:0035194 25 0.080
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.080
regulation of smooth muscle cell apoptotic process GO:0034391 6 0.079
response to external biotic stimulus GO:0043207 261 0.078
gene silencing by mirna GO:0035195 23 0.076
circulatory system development GO:0072359 262 0.076
negative regulation of cell fate commitment GO:0010454 3 0.075
mrna 3 end processing GO:0031124 24 0.075
regulation of signal transduction by p53 class mediator GO:1901796 26 0.075
hindbrain development GO:0030902 3 0.073
epidermis development GO:0008544 59 0.070
double strand break repair GO:0006302 101 0.069
regulation of translation GO:0006417 89 0.067
taxis GO:0042330 157 0.067
ribonucleoprotein complex disassembly GO:0032988 7 0.064
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.063
Fly
ion homeostasis GO:0050801 230 0.063
positive regulation of cell activation GO:0050867 81 0.062
signal transduction involved in dna integrity checkpoint GO:0072401 15 0.061
single organism reproductive process GO:0044702 98 0.061
Worm
divalent inorganic cation homeostasis GO:0072507 136 0.058
nervous system development GO:0007399 293 0.058
Fly
central nervous system development GO:0007417 123 0.057
protein oligomerization GO:0051259 173 0.057
regulation of lipid transport by regulation of transcription from rna polymerase ii promoter GO:0072367 4 0.056
cell junction assembly GO:0034329 67 0.056
low density lipoprotein particle clearance GO:0034383 8 0.055
vesicle mediated transport GO:0016192 371 0.054
myoblast fusion GO:0007520 1 0.053
osteoblast differentiation GO:0001649 92 0.053
epithelial cell differentiation GO:0030855 141 0.052
positive regulation of phosphorylation GO:0042327 394 0.052
positive regulation of transport GO:0051050 336 0.052
Fly
translation GO:0006412 132 0.051
endodermal cell fate specification GO:0001714 4 0.050
myeloid cell differentiation GO:0030099 117 0.050
multicellular organismal reproductive process GO:0048609 40 0.048
Worm
somatic muscle development GO:0007525 1 0.045
embryo development ending in birth or egg hatching GO:0009792 34 0.045
Worm
cation transport GO:0006812 331 0.045
cell substrate junction assembly GO:0007044 35 0.045
regulation of muscle cell differentiation GO:0051147 31 0.043
mitotic spindle organization GO:0007052 27 0.043
Fly
regulation of homeostatic process GO:0032844 121 0.041
spermatid differentiation GO:0048515 4 0.040
chemical homeostasis GO:0048878 306 0.040
chemotaxis GO:0006935 157 0.039
actin filament based process GO:0030029 224 0.039
spindle organization GO:0007051 53 0.038
Fly
defense response GO:0006952 315 0.037
blastocyst development GO:0001824 3 0.036
metal ion transport GO:0030001 272 0.035
heart field specification GO:0003128 2 0.035
epithelium development GO:0060429 227 0.034
ossification GO:0001503 121 0.033
protein targeting GO:0006605 187 0.033
tissue homeostasis GO:0001894 63 0.033
cardiovascular system development GO:0072358 262 0.033
regulation of glial cell differentiation GO:0045685 3 0.032
cytosolic calcium ion homeostasis GO:0051480 89 0.032
cellular homeostasis GO:0019725 196 0.031
gamete generation GO:0007276 25 0.031
Worm
sex differentiation GO:0007548 45 0.030
Worm
retinal ganglion cell axon guidance GO:0031290 2 0.030
regulation of intracellular transport GO:0032386 195 0.030
Fly
regulation of nervous system development GO:0051960 88 0.029
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.029
regulation of receptor mediated endocytosis GO:0048259 32 0.029
regulation of mapk cascade GO:0043408 262 0.029
regulation of response to dna damage stimulus GO:2001020 94 0.029
smooth muscle cell apoptotic process GO:0034390 6 0.028
somatic stem cell maintenance GO:0035019 4 0.028
muscle cell fate commitment GO:0042693 4 0.028
proteasomal protein catabolic process GO:0010498 176 0.027
multi multicellular organism process GO:0044706 18 0.027
protein localization to organelle GO:0033365 280 0.027
regulation of cellular response to stress GO:0080135 244 0.026
regulation of gene expression epigenetic GO:0040029 73 0.026
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.025
posttranscriptional gene silencing GO:0016441 25 0.025
sexual reproduction GO:0019953 37 0.025
Worm
microtubule based process GO:0007017 210 0.025
Fly
mapk cascade GO:0000165 288 0.025
neuromuscular junction development GO:0007528 3 0.024
signal transduction by phosphorylation GO:0023014 297 0.024
ncrna processing GO:0034470 83 0.024
regulation of leukocyte activation GO:0002694 115 0.024
regulation of definitive erythrocyte differentiation GO:0010724 2 0.023
genitalia development GO:0048806 10 0.023
Worm
neurogenesis GO:0022008 169 0.023
Fly
protein import GO:0017038 130 0.023
dna repair GO:0006281 198 0.023
mrna catabolic process GO:0006402 56 0.023
positive regulation of mapk cascade GO:0043410 190 0.023
syncytium formation by plasma membrane fusion GO:0000768 2 0.023
notch signaling pathway GO:0007219 31 0.022
positive regulation of nervous system development GO:0051962 54 0.022
regulation of cytoskeleton organization GO:0051493 177 0.021
aging GO:0007568 66 0.021
positive regulation of neurogenesis GO:0050769 49 0.021
morphogenesis of embryonic epithelium GO:0016331 4 0.020
negative regulation of mitotic cell cycle GO:0045930 102 0.020
positive regulation of astrocyte differentiation GO:0048711 2 0.020
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.020
dna integrity checkpoint GO:0031570 71 0.020
rhythmic behavior GO:0007622 2 0.020
generation of neurons GO:0048699 152 0.020
regulation of protein transport GO:0051223 213 0.020
erk1 and erk2 cascade GO:0070371 104 0.019
reproduction GO:0000003 63 0.019
Worm
vasculature development GO:0001944 181 0.019
endodermal cell fate commitment GO:0001711 4 0.019
cation homeostasis GO:0055080 189 0.019
response to light stimulus GO:0009416 87 0.018
nuclear division GO:0000280 128 0.018
Worm
response to nitrogen compound GO:1901698 184 0.018
cell projection morphogenesis GO:0048858 129 0.018
signal transduction involved in dna damage checkpoint GO:0072422 15 0.018
response to biotic stimulus GO:0009607 276 0.018
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.017
regulation of cell development GO:0060284 161 0.017
muscle system process GO:0003012 81 0.017
chordate embryonic development GO:0043009 34 0.017
negative regulation of multicellular organismal process GO:0051241 317 0.017
primary neural tube formation GO:0014020 3 0.017
regulation of lipid biosynthetic process GO:0046890 47 0.017
multi organism cellular process GO:0044764 156 0.017
cellular ion homeostasis GO:0006873 168 0.016
negative regulation of catalytic activity GO:0043086 335 0.016
response to abiotic stimulus GO:0009628 336 0.016
positive regulation of rna export from nucleus GO:0046833 1 0.015
Fly
receptor mediated endocytosis GO:0006898 84 0.015
negative regulation of cell cycle process GO:0010948 121 0.015
nitrogen compound transport GO:0071705 191 0.015
Fly
signal transduction by p53 class mediator GO:0072331 72 0.015
rna interference GO:0016246 4 0.015
cardiac muscle cell contraction GO:0086003 4 0.014
oocyte development GO:0048599 1 0.014
cerebellum development GO:0021549 2 0.014
anatomical structure formation involved in morphogenesis GO:0048646 284 0.014
system process GO:0003008 349 0.014
response to uv GO:0009411 73 0.014
negative regulation of phosphate metabolic process GO:0045936 267 0.014
cell type specific apoptotic process GO:0097285 125 0.014
myeloid cell homeostasis GO:0002262 34 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
cellular cation homeostasis GO:0030003 163 0.014
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.014
regulation of cell activation GO:0050865 125 0.014
dna damage checkpoint GO:0000077 68 0.014
epithelial cell proliferation involved in lung morphogenesis GO:0060502 3 0.013
non recombinational repair GO:0000726 14 0.013
negative regulation of developmental process GO:0051093 247 0.013
cell part morphogenesis GO:0032990 137 0.013
regulation of neurogenesis GO:0050767 82 0.013
divalent inorganic cation transport GO:0072511 158 0.013
negative regulation of cell fate specification GO:0009996 3 0.013
small gtpase mediated signal transduction GO:0007264 78 0.013
response to oxidative stress GO:0006979 121 0.013
cellular lipid metabolic process GO:0044255 303 0.013
neurological system process GO:0050877 163 0.013
regulation of low density lipoprotein particle receptor biosynthetic process GO:0045714 4 0.013
positive regulation of immune system process GO:0002684 283 0.013
organelle fission GO:0048285 149 0.012
Worm
multicellular organismal aging GO:0010259 3 0.012
regulation of skeletal muscle cell differentiation GO:2001014 3 0.012
cell projection organization GO:0030030 252 0.012
metencephalon development GO:0022037 2 0.012
neuron apoptotic process GO:0051402 39 0.012
regulation of cell cycle phase transition GO:1901987 126 0.012
post embryonic development GO:0009791 2 0.012
Worm
negative regulation of protein metabolic process GO:0051248 391 0.012
negative regulation of protein complex disassembly GO:0043242 20 0.012
regulation of ion homeostasis GO:2000021 73 0.012
mating GO:0007618 1 0.012
regulation of cell growth GO:0001558 135 0.012
negative regulation of programmed cell death GO:0043069 321 0.012
brain development GO:0007420 97 0.012
dephosphorylation GO:0016311 209 0.012
negative regulation of response to external stimulus GO:0032102 83 0.012
regulation of vesicle mediated transport GO:0060627 130 0.012
establishment of tissue polarity GO:0007164 3 0.011
regulation of cellular ketone metabolic process GO:0010565 50 0.011
positive regulation of cell development GO:0010720 92 0.011
negative regulation of phosphatase activity GO:0010923 61 0.011
regulation of endocytosis GO:0030100 72 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
cellular metal ion homeostasis GO:0006875 146 0.011
inner ear morphogenesis GO:0042472 4 0.011
nuclear import GO:0051170 106 0.011
specification of organ identity GO:0010092 3 0.011
lymphocyte activation GO:0046649 133 0.011
i kappab kinase nf kappab signaling GO:0007249 166 0.011
neural tube formation GO:0001841 3 0.011
positive regulation of protein transport GO:0051222 135 0.011
ras protein signal transduction GO:0007265 73 0.011
negative regulation of fertilization GO:0060467 2 0.011
response to oxygen containing compound GO:1901700 369 0.011
chromosome segregation GO:0007059 114 0.011
positive regulation of t cell activation GO:0050870 54 0.011
regulation of actin cytoskeleton organization GO:0032956 116 0.010
regulation of purine nucleotide metabolic process GO:1900542 264 0.010
positive regulation of mrna metabolic process GO:1903313 19 0.010
meiotic chromosome segregation GO:0045132 4 0.010
positive regulation of secretion by cell GO:1903532 108 0.010
response to other organism GO:0051707 261 0.010
actin cytoskeleton organization GO:0030036 207 0.010
immune response GO:0006955 307 0.010
monocarboxylic acid biosynthetic process GO:0072330 67 0.010

U2AF2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.066
cancer DOID:162 167 0.044
organ system cancer DOID:0050686 164 0.037
disease of metabolism DOID:0014667 295 0.012
acquired metabolic disease DOID:0060158 58 0.012