Homo sapiens

86 known processes

UBE2C

ubiquitin-conjugating enzyme E2C

(Aliases: UBCH10,dJ447F3.2)

UBE2C biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of chromosome segregation GO:0051983 44 0.594
Fly
nuclear division GO:0000280 128 0.581
sister chromatid segregation GO:0000819 54 0.512
Fly
mitotic sister chromatid segregation GO:0000070 53 0.497
Fly
mitotic cell cycle process GO:1903047 286 0.468
deoxyribose phosphate metabolic process GO:0019692 6 0.361
ubiquitin dependent protein catabolic process GO:0006511 206 0.339
organelle fission GO:0048285 149 0.332
negative regulation of organelle organization GO:0010639 126 0.305
regulation of cell cycle GO:0051726 393 0.295
regulation of cell cycle process GO:0010564 266 0.292
positive regulation of cell cycle process GO:0090068 106 0.288
mitotic cell cycle GO:0000278 326 0.252
negative regulation of cellular component organization GO:0051129 235 0.241
cellular macromolecule catabolic process GO:0044265 380 0.227
protein ubiquitination GO:0016567 314 0.214
mitotic nuclear division GO:0007067 119 0.208
negative regulation of cellular protein metabolic process GO:0032269 353 0.206
spindle assembly GO:0051225 29 0.170
microtubule based process GO:0007017 210 0.163
negative regulation of protein metabolic process GO:0051248 391 0.160
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.151
regulation of protein processing GO:0070613 150 0.144
positive regulation of cellular component organization GO:0051130 376 0.141
positive regulation of exit from mitosis GO:0031536 2 0.137
regulation of mitotic cell cycle GO:0007346 189 0.134
spindle organization GO:0007051 53 0.126
organelle assembly GO:0070925 176 0.118
nucleoside monophosphate metabolic process GO:0009123 191 0.118
protein catabolic process GO:0030163 325 0.111
negative regulation of proteolysis GO:0045861 132 0.109
cellular amine metabolic process GO:0044106 41 0.105
regulation of nuclear division GO:0051783 65 0.104
mitotic cell cycle phase transition GO:0044772 162 0.103
Fly
positive regulation of cell cycle GO:0045787 140 0.102
protein processing GO:0016485 226 0.098
regulation of protein maturation GO:1903317 150 0.091
positive regulation of developmental process GO:0051094 314 0.091
meiotic chromosome segregation GO:0045132 4 0.089
metaphase anaphase transition of cell cycle GO:0044784 21 0.089
Fly
regulation of cellular ketone metabolic process GO:0010565 50 0.087
regulation of cell differentiation GO:0045595 393 0.086
modification dependent macromolecule catabolic process GO:0043632 212 0.083
cell division GO:0051301 168 0.083
female gamete generation GO:0007292 2 0.081
negative regulation of protein processing GO:0010955 142 0.078
negative regulation of cell death GO:0060548 345 0.077
negative regulation of phosphorus metabolic process GO:0010563 267 0.077
regulation of cellular component biogenesis GO:0044087 281 0.077
protein maturation GO:0051604 233 0.072
microtubule cytoskeleton organization GO:0000226 176 0.070
anterior posterior axis specification GO:0009948 2 0.070
oocyte differentiation GO:0009994 2 0.069
regulation of cellular amine metabolic process GO:0033238 11 0.069
protein modification by small protein conjugation GO:0032446 342 0.068
negative regulation of protein maturation GO:1903318 142 0.067
negative regulation of cell differentiation GO:0045596 171 0.066
cellular protein complex assembly GO:0043623 188 0.066
regulation of mitosis GO:0007088 63 0.065
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.064
Fly
regulation of microtubule based process GO:0032886 74 0.063
positive regulation of mitosis GO:0045840 25 0.063
proteasomal protein catabolic process GO:0010498 176 0.063
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.062
ribonucleoside triphosphate metabolic process GO:0009199 412 0.061
cellular amino acid metabolic process GO:0006520 116 0.060
ribonucleoside monophosphate metabolic process GO:0009161 187 0.060
cell development GO:0048468 328 0.059
cellular macromolecular complex assembly GO:0034622 324 0.058
cellular component disassembly GO:0022411 92 0.058
oogenesis GO:0048477 2 0.058
establishment of nucleus localization GO:0040023 1 0.056
negative regulation of mitotic metaphase anaphase transition GO:0045841 17 0.056
ribonucleoside catabolic process GO:0042454 406 0.055
microtubule polymerization or depolymerization GO:0031109 37 0.054
histone serine phosphorylation GO:0035404 4 0.054
cellular protein complex disassembly GO:0043624 36 0.053
negative regulation of peptidase activity GO:0010466 91 0.053
cellular response to dna damage stimulus GO:0006974 379 0.052
regulation of cell division GO:0051302 116 0.051
negative regulation of hydrolase activity GO:0051346 182 0.051
cell cycle phase transition GO:0044770 173 0.051
Fly
meiosis i GO:0007127 4 0.050
immune response GO:0006955 307 0.050
microtubule organizing center organization GO:0031023 62 0.050
chromatin modification GO:0016568 298 0.049
regulation of proteolysis GO:0030162 293 0.049
Fly
male meiosis GO:0007140 1 0.049
regulation of transferase activity GO:0051338 355 0.048
cell cycle checkpoint GO:0000075 117 0.048
dna repair GO:0006281 198 0.047
covalent chromatin modification GO:0016569 254 0.047
purine nucleoside catabolic process GO:0006152 398 0.047
ribonucleoside triphosphate catabolic process GO:0009203 391 0.047
chromosome segregation GO:0007059 114 0.047
Fly
nucleoside triphosphate catabolic process GO:0009143 394 0.045
negative regulation of programmed cell death GO:0043069 321 0.045
negative regulation of cell cycle GO:0045786 193 0.044
regulation of cellular amino acid metabolic process GO:0006521 6 0.043
regulation of cell cycle phase transition GO:1901987 126 0.043
Fly
regulation of attachment of spindle microtubules to kinetochore GO:0051988 9 0.042
regulation of microtubule cytoskeleton organization GO:0070507 61 0.042
positive regulation of cellular amine metabolic process GO:0033240 7 0.041
ribonucleoside monophosphate catabolic process GO:0009158 158 0.041
positive regulation of transferase activity GO:0051347 227 0.040
response to biotic stimulus GO:0009607 276 0.040
oocyte maturation GO:0001556 1 0.040
mitotic sister chromatid separation GO:0051306 18 0.039
Fly
negative regulation of apoptotic process GO:0043066 316 0.039
purine nucleoside monophosphate metabolic process GO:0009126 186 0.039
single organism cellular localization GO:1902580 332 0.039
spindle assembly involved in mitosis GO:0090307 12 0.038
purine nucleoside triphosphate catabolic process GO:0009146 392 0.038
regulation of protein complex assembly GO:0043254 147 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
regulation of cytoskeleton organization GO:0051493 177 0.038
cellular ketone metabolic process GO:0042180 80 0.038
positive regulation of mitotic cell cycle GO:0045931 60 0.037
modification dependent protein catabolic process GO:0019941 209 0.037
negative regulation of endopeptidase activity GO:0010951 84 0.037
dna conformation change GO:0071103 113 0.037
immune effector process GO:0002252 159 0.037
mrna metabolic process GO:0016071 175 0.036
establishment of organelle localization GO:0051656 59 0.036
positive regulation of chromosome organization GO:2001252 41 0.036
Fly
nucleus localization GO:0051647 1 0.036
nervous system development GO:0007399 293 0.035
positive regulation of mitotic sister chromatid separation GO:1901970 6 0.035
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.034
regulation of cell development GO:0060284 161 0.034
dna damage response signal transduction resulting in transcription GO:0042772 12 0.033
centrosome separation GO:0051299 3 0.033
nucleotide biosynthetic process GO:0009165 109 0.032
spindle checkpoint GO:0031577 26 0.032
ribonucleotide catabolic process GO:0009261 405 0.032
organophosphate catabolic process GO:0046434 430 0.032
cellular protein catabolic process GO:0044257 261 0.032
dna integrity checkpoint GO:0031570 71 0.031
regulation of endopeptidase activity GO:0052548 170 0.031
post embryonic development GO:0009791 2 0.030
negative regulation of developmental process GO:0051093 247 0.030
purine ribonucleoside metabolic process GO:0046128 437 0.030
golgi disassembly GO:0090166 2 0.029
negative regulation of cell cycle process GO:0010948 121 0.029
regulation of binding GO:0051098 111 0.029
photoreceptor cell differentiation GO:0046530 2 0.029
negative regulation of phosphate metabolic process GO:0045936 267 0.028
microtubule polymerization GO:0046785 18 0.028
negative regulation of cell cycle phase transition GO:1901988 89 0.028
negative regulation of catalytic activity GO:0043086 335 0.028
regulation of protein localization GO:0032880 296 0.028
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.028
clearance of foreign intracellular dna by conversion of dna cytidine to uridine GO:0044356 1 0.027
atp metabolic process GO:0046034 176 0.027
regeneration GO:0031099 4 0.027
nucleotide catabolic process GO:0009166 408 0.027
regulation of immune response GO:0050776 201 0.027
cardiovascular system development GO:0072358 262 0.027
dephosphorylation GO:0016311 209 0.026
negative regulation of multicellular organismal process GO:0051241 317 0.026
negative regulation of sister chromatid segregation GO:0033046 17 0.026
negative regulation of chromosome organization GO:2001251 48 0.026
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.026
negative regulation of protein modification process GO:0031400 200 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.025
multicellular organismal aging GO:0010259 3 0.025
regulation of mitotic cell cycle phase transition GO:1901990 118 0.024
Fly
cytokinesis GO:0000910 96 0.024
mitotic cell cycle checkpoint GO:0007093 68 0.024
cell morphogenesis GO:0000902 296 0.024
nucleoside triphosphate metabolic process GO:0009141 422 0.024
protein complex disassembly GO:0043241 52 0.024
protein polymerization GO:0051258 71 0.024
dna duplex unwinding GO:0032508 30 0.024
purine nucleoside monophosphate catabolic process GO:0009128 158 0.024
nucleoside catabolic process GO:0009164 408 0.024
positive regulation of phosphorylation GO:0042327 394 0.024
positive regulation of organelle organization GO:0010638 195 0.024
response to oxygen containing compound GO:1901700 369 0.024
maintenance of location GO:0051235 112 0.024
cell cycle g1 s phase transition GO:0044843 80 0.023
membrane organization GO:0061024 292 0.023
methylation GO:0032259 106 0.023
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.023
oocyte development GO:0048599 1 0.023
mitotic spindle elongation GO:0000022 4 0.023
purine ribonucleoside catabolic process GO:0046130 398 0.022
microtubule cytoskeleton organization involved in mitosis GO:1902850 15 0.022
carbohydrate derivative biosynthetic process GO:1901137 207 0.022
nucleoside phosphate catabolic process GO:1901292 412 0.022
spindle midzone assembly GO:0051255 4 0.022
negative regulation of methylation dependent chromatin silencing GO:0090310 2 0.022
organophosphate biosynthetic process GO:0090407 163 0.022
negative regulation of catabolic process GO:0009895 104 0.022
determination of adult lifespan GO:0008340 2 0.021
activation of mitotic anaphase promoting complex activity GO:0007092 2 0.021
regulation of multi organism process GO:0043900 157 0.021
sister chromatid cohesion GO:0007062 24 0.021
regulation of chromosome organization GO:0033044 103 0.021
Fly
microtubule based movement GO:0007018 32 0.021
negative regulation of mitotic cell cycle GO:0045930 102 0.020
positive regulation of protein kinase activity GO:0045860 190 0.020
cellular response to endogenous stimulus GO:0071495 336 0.020
microtubule nucleation GO:0007020 6 0.020
histone modification GO:0016570 251 0.020
cellular component morphogenesis GO:0032989 314 0.020
multi organism cellular process GO:0044764 156 0.020
nucleoside phosphate biosynthetic process GO:1901293 109 0.020
negative regulation of microtubule polymerization or depolymerization GO:0031111 17 0.020
interspecies interaction between organisms GO:0044419 156 0.020
cell part morphogenesis GO:0032990 137 0.020
immune system development GO:0002520 195 0.019
positive regulation of catabolic process GO:0009896 310 0.019
Fly
cellular homeostasis GO:0019725 196 0.019
purine ribonucleotide catabolic process GO:0009154 404 0.019
endocytosis GO:0006897 159 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.019
negative regulation of cellular catabolic process GO:0031330 83 0.019
circulatory system development GO:0072359 262 0.019
negative regulation of phosphorylation GO:0042326 174 0.019
cytidine catabolic process GO:0006216 7 0.019
chromatin organization GO:0006325 351 0.018
establishment of cell polarity GO:0030010 22 0.018
rna splicing GO:0008380 131 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.018
negative regulation of dephosphorylation GO:0035305 63 0.018
glomerular epithelial cell development GO:0072310 3 0.018
cytoplasmic transport GO:0016482 379 0.017
generation of neurons GO:0048699 152 0.017
macromolecular complex disassembly GO:0032984 60 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.017
centrosome organization GO:0051297 58 0.017
protein k11 linked ubiquitination GO:0070979 24 0.017
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 17 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
dna replication GO:0006260 116 0.017
regulation of peptidase activity GO:0052547 180 0.017
regulation of kinase activity GO:0043549 314 0.017
response to external biotic stimulus GO:0043207 261 0.017
cell cycle g2 m phase transition GO:0044839 43 0.017
cyclin catabolic process GO:0008054 6 0.016
regulation of homeostatic process GO:0032844 121 0.016
peptidyl serine modification GO:0018209 106 0.016
purine containing compound catabolic process GO:0072523 411 0.016
organonitrogen compound biosynthetic process GO:1901566 200 0.016
anatomical structure formation involved in morphogenesis GO:0048646 284 0.016
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.016
actin filament based process GO:0030029 224 0.016
embryo development GO:0009790 123 0.016
purine nucleoside triphosphate metabolic process GO:0009144 412 0.016
negative regulation of mitotic sister chromatid separation GO:2000816 17 0.015
growth GO:0040007 202 0.015
regulation of cellular response to stress GO:0080135 244 0.015
regulation of cell activation GO:0050865 125 0.015
eye photoreceptor cell differentiation GO:0001754 2 0.015
nucleoside monophosphate catabolic process GO:0009125 159 0.015
positive regulation of cellular catabolic process GO:0031331 284 0.015
Fly
atp catabolic process GO:0006200 157 0.015
nitrogen compound transport GO:0071705 191 0.015
neurogenesis GO:0022008 169 0.015
stem cell differentiation GO:0048863 93 0.015
response to hypoxia GO:0001666 96 0.014
cellular lipid metabolic process GO:0044255 303 0.014
regulation of dna binding GO:0051101 37 0.014
mapk cascade GO:0000165 288 0.014
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.014
cell projection organization GO:0030030 252 0.014
protein localization to organelle GO:0033365 280 0.014
regulation of mitotic sister chromatid separation GO:0010965 27 0.014
Fly
glycosyl compound catabolic process GO:1901658 413 0.014
positive regulation of dna metabolic process GO:0051054 73 0.014
chemical homeostasis GO:0048878 306 0.014
regulation of protein kinase activity GO:0045859 289 0.014
regulation of protein ubiquitination GO:0031396 95 0.014
cytoskeleton dependent cytokinesis GO:0061640 22 0.013
response to abiotic stimulus GO:0009628 336 0.013
dna recombination GO:0006310 77 0.013
neuromuscular junction development GO:0007528 3 0.013
defense response GO:0006952 315 0.013
positive regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051437 2 0.013
response to oxygen levels GO:0070482 100 0.013
spermatid differentiation GO:0048515 4 0.013
regulation of mrna metabolic process GO:1903311 53 0.013
regulation of protein serine threonine kinase activity GO:0071900 179 0.013
regulation of proteasomal protein catabolic process GO:0061136 87 0.013
Fly
stem cell development GO:0048864 69 0.013
protein depolymerization GO:0051261 30 0.013
sister chromatid biorientation GO:0031134 2 0.012
viral process GO:0016032 146 0.012
response to other organism GO:0051707 261 0.012
amine metabolic process GO:0009308 44 0.012
negative regulation of cellular protein catabolic process GO:1903363 38 0.012
regulation of protein stability GO:0031647 87 0.012
protein dna complex subunit organization GO:0071824 80 0.012
cell activation GO:0001775 213 0.012
single organism membrane organization GO:0044802 268 0.012
positive regulation of cell activation GO:0050867 81 0.012
peptidyl serine phosphorylation GO:0018105 101 0.012
viral life cycle GO:0019058 132 0.012
positive regulation of immune system process GO:0002684 283 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.012
positive regulation of histone modification GO:0031058 29 0.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.011
nuclear migration GO:0007097 1 0.011
cellular response to oxygen containing compound GO:1901701 276 0.011
response to decreased oxygen levels GO:0036293 96 0.011
lymphocyte activation GO:0046649 133 0.011
reproduction GO:0000003 63 0.011
mitotic cytokinesis GO:0000281 19 0.011
cell cycle arrest GO:0007050 71 0.011
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 35 0.011
rna processing GO:0006396 255 0.011
negative regulation of protein catabolic process GO:0042177 59 0.011
response to oxidative stress GO:0006979 121 0.011
single organism reproductive process GO:0044702 98 0.011
centrosome cycle GO:0007098 32 0.011
secretion GO:0046903 254 0.011
protein dephosphorylation GO:0006470 81 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.010
spindle stabilization GO:0043146 4 0.010
organelle localization GO:0051640 84 0.010
regulation of mapk cascade GO:0043408 262 0.010
mitotic spindle midzone assembly GO:0051256 4 0.010
regulation of cell adhesion GO:0030155 166 0.010
positive regulation of multi organism process GO:0043902 56 0.010
positive regulation of lymphocyte activation GO:0051251 73 0.010
cellular response to oxygen levels GO:0071453 55 0.010
macromolecule methylation GO:0043414 97 0.010
positive regulation of cell differentiation GO:0045597 211 0.010

UBE2C disease predictions

Disease DO term ID Size Probability Func Analog Org
gastrointestinal system cancer DOID:3119 52 0.031
cancer DOID:162 167 0.031
disease of cellular proliferation DOID:14566 174 0.031
organ system cancer DOID:0050686 164 0.031