|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
1.000
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
1.000
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
1.000
|
|
|
|
protein k11 linked ubiquitination
|
GO:0070979 |
24 |
1.000
|
Human |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
1.000
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
1.000
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
1.000
|
|
|
|
protein k63 linked ubiquitination
|
GO:0070534 |
31 |
0.999
|
Human |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.999
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.999
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.998
|
|
|
|
protein k27 linked ubiquitination
|
GO:0044314 |
4 |
0.997
|
Human |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.995
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.994
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.986
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.953
|
|
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.929
|
|
|
|
protein autoubiquitination
|
GO:0051865 |
37 |
0.919
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.916
|
|
|
|
protein monoubiquitination
|
GO:0006513 |
39 |
0.897
|
Human Yeast |
|
|
isg15 protein conjugation
|
GO:0032020 |
5 |
0.884
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.878
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.854
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.844
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.785
|
Yeast |
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.773
|
|
|
|
regulation of protein deubiquitination
|
GO:0090085 |
4 |
0.741
|
|
|
|
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway
|
GO:0043162 |
10 |
0.706
|
Yeast |
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.695
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.656
|
Human |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.641
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.602
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.595
|
|
|
|
protein k29 linked ubiquitination
|
GO:0035519 |
4 |
0.584
|
Human |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.575
|
Human |
|
|
negative regulation of ion transmembrane transport
|
GO:0034766 |
26 |
0.562
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.534
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.478
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.467
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.462
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.456
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.454
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.451
|
|
|
|
entry into other organism involved in symbiotic interaction
|
GO:0051828 |
25 |
0.425
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.424
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.399
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.386
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.381
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.376
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.372
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.366
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.359
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.329
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.329
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.322
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.320
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.317
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.312
|
|
|
|
histone monoubiquitination
|
GO:0010390 |
20 |
0.303
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.290
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.289
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.288
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.277
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.266
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.246
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.242
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.241
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.241
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.233
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.232
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.224
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.223
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.223
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.222
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.221
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.219
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.219
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.218
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.217
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.214
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.211
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.207
|
|
|
|
neutrophil clearance
|
GO:0097350 |
1 |
0.207
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.206
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.202
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.202
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.200
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.198
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.197
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.193
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.192
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.183
|
|
|
|
entry into host
|
GO:0044409 |
25 |
0.182
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.182
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.179
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.172
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.172
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.167
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.167
|
|
|
|
cellular response to heat
|
GO:0034605 |
14 |
0.166
|
Yeast |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.164
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.159
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.159
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.156
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.155
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.151
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.151
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.148
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.147
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.147
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.146
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.145
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.145
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.145
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.145
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.144
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.144
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.142
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.142
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.140
|
|
|
|
protein destabilization
|
GO:0031648 |
12 |
0.139
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.137
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.135
|
|
|
|
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:2000059 |
3 |
0.131
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.131
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.131
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.130
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.130
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.130
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.128
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.127
|
|
|
|
viral release from host cell
|
GO:0019076 |
21 |
0.125
|
|
|
|
negative regulation of camp mediated signaling
|
GO:0043951 |
4 |
0.125
|
|
|
|
regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033143 |
32 |
0.123
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.122
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.122
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.119
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.119
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.118
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.117
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.115
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.115
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.115
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.114
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.113
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.111
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.110
|
|
|
|
histone h2b ubiquitination
|
GO:0033523 |
8 |
0.109
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.104
|
|
|
|
negative regulation of protein secretion
|
GO:0050709 |
29 |
0.103
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.103
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.102
|
|
|
|
actin nucleation
|
GO:0045010 |
21 |
0.102
|
|
|
|
negative regulation of transmembrane transport
|
GO:0034763 |
29 |
0.101
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.100
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.099
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.099
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.097
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.095
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.094
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.094
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.094
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.093
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.092
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.092
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.092
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.091
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.089
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.089
|
|
|
|
androgen receptor signaling pathway
|
GO:0030521 |
34 |
0.088
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.087
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.086
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.085
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.084
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.084
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.082
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.082
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.082
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.081
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.080
|
|
|
|
response to salt stress
|
GO:0009651 |
3 |
0.079
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.079
|
|
|
|
negative regulation of cytokine secretion
|
GO:0050710 |
20 |
0.078
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.077
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.077
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.076
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.076
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.075
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.071
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.071
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.070
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.070
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.070
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.069
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.069
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.069
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.068
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.068
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.068
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.067
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.066
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.066
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.066
|
|
|
|
regulation of viral entry into host cell
|
GO:0046596 |
17 |
0.065
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.065
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.064
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.064
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.063
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.063
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.062
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.061
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.061
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.061
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.061
|
|
|
|
dolichol metabolic process
|
GO:0019348 |
3 |
0.059
|
|
|
|
regulation of macrophage differentiation
|
GO:0045649 |
9 |
0.059
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.059
|
|
|
|
interleukin 2 secretion
|
GO:0070970 |
3 |
0.057
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.057
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.056
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.056
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.055
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.055
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.053
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.053
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.053
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.052
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.052
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.052
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.051
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.051
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.050
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.050
|
|
|
|
neutrophil degranulation
|
GO:0043312 |
3 |
0.049
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.049
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.048
|
|
|
|
cardiac right ventricle morphogenesis
|
GO:0003215 |
3 |
0.048
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.048
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.048
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.047
|
|
|
|
positive regulation of myeloid cell apoptotic process
|
GO:0033034 |
2 |
0.047
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.046
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.045
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.045
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.045
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.044
|
|
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.044
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.043
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.043
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.043
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.043
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.042
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.042
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
15 |
0.041
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.041
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.041
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.041
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.041
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.040
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.040
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.040
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.040
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.039
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.039
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.039
|
|
|
|
protein heterotetramerization
|
GO:0051290 |
3 |
0.039
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.039
|
|
|
|
centrosome separation
|
GO:0051299 |
3 |
0.038
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.038
|
|
|
|
histone h2a ubiquitination
|
GO:0033522 |
17 |
0.038
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.038
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
35 |
0.038
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.037
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.037
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.036
|
|
|
|
positive regulation of protein polyubiquitination
|
GO:1902916 |
3 |
0.036
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.035
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.035
|
|
|
|
nucleobase containing compound transport
|
GO:0015931 |
51 |
0.035
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.035
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.035
|
|
|
|
head development
|
GO:0060322 |
108 |
0.035
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.034
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.034
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.034
|
|
|
|
negative regulation of transcription elongation from rna polymerase ii promoter
|
GO:0034244 |
4 |
0.034
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.033
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.033
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.033
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.033
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.033
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.033
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.033
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.033
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.033
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.032
|
|
|
|
positive regulation of vesicle fusion
|
GO:0031340 |
4 |
0.032
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.032
|
|
|
|
cellular response to light stimulus
|
GO:0071482 |
34 |
0.032
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.032
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.032
|
|
|
|
regulation of interleukin 8 secretion
|
GO:2000482 |
13 |
0.031
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.031
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.031
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.031
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.030
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.030
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.030
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.030
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.029
|
|
|
|
cellular response to muramyl dipeptide
|
GO:0071225 |
3 |
0.029
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.029
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.029
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.029
|
|
|
|
positive regulation of ligase activity
|
GO:0051351 |
19 |
0.028
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.028
|
|
|
|
polyprenol biosynthetic process
|
GO:0016094 |
1 |
0.028
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.028
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.028
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.027
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.027
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.027
|
|
|
|
negative regulation of protein polyubiquitination
|
GO:1902915 |
4 |
0.026
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.026
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.026
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.026
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.026
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.026
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.026
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.026
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.026
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.026
|
|
|
|
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:2000058 |
7 |
0.026
|
|
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.026
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.026
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.025
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.025
|
|
|
|
coenzyme biosynthetic process
|
GO:0009108 |
24 |
0.025
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.025
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.025
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.025
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.025
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.025
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
30 |
0.025
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.025
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.024
|
|
|
|
amide biosynthetic process
|
GO:0043604 |
15 |
0.024
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.024
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.024
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.024
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.024
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.024
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
25 |
0.024
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.023
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.023
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.023
|
|
|
|
protein k48 linked deubiquitination
|
GO:0071108 |
19 |
0.023
|
|
|
|
positive regulation of neutrophil apoptotic process
|
GO:0033031 |
1 |
0.023
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.023
|
|
|
|
regulation of viral release from host cell
|
GO:1902186 |
20 |
0.023
|
|
|
|
regulation of endosome size
|
GO:0051036 |
3 |
0.023
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.023
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.023
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.023
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.023
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.022
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.022
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.022
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.022
|
|
|
|
membrane lipid metabolic process
|
GO:0006643 |
53 |
0.022
|
|
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.022
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.022
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.022
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.022
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.022
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.022
|
|
|
|
isoprenoid metabolic process
|
GO:0006720 |
39 |
0.022
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.022
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.021
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.021
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.021
|
|
|
|
centrosome cycle
|
GO:0007098 |
32 |
0.021
|
|
|
|
aging
|
GO:0007568 |
66 |
0.021
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.021
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.021
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.021
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.021
|
|
|
|
midbrain development
|
GO:0030901 |
45 |
0.021
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.021
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.021
|
|
|
|
movement in environment of other organism involved in symbiotic interaction
|
GO:0052192 |
25 |
0.021
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.021
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.021
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.021
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.021
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.021
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.021
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.020
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.020
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.020
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.020
|
|
|
|
negative regulation of jnk cascade
|
GO:0046329 |
16 |
0.020
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
101 |
0.020
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.020
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.020
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.020
|
|
|
|
negative regulation of interleukin 8 secretion
|
GO:2000483 |
2 |
0.020
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.020
|
|
|
|
osteoclast development
|
GO:0036035 |
2 |
0.020
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.020
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.020
|
|
|
|
membrane budding
|
GO:0006900 |
28 |
0.019
|
|
|
|
response to cobalt ion
|
GO:0032025 |
1 |
0.019
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.019
|
|
|
|
interleukin 8 secretion
|
GO:0072606 |
14 |
0.019
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.019
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.019
|
|
|
|
toll like receptor 2 signaling pathway
|
GO:0034134 |
4 |
0.019
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.019
|
|
|
|
negative regulation of leukocyte activation
|
GO:0002695 |
26 |
0.019
|
|
|
|
regulation of protein linear polyubiquitination
|
GO:1902528 |
2 |
0.019
|
|
|
|
regulation of interleukin 2 secretion
|
GO:1900040 |
2 |
0.019
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.019
|
|
|
|
endosome organization
|
GO:0007032 |
20 |
0.019
|
|
|
|
sulfur compound biosynthetic process
|
GO:0044272 |
38 |
0.019
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
63 |
0.019
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.018
|
|
|
|
negative regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903556 |
20 |
0.018
|
|
|
|
negative regulation of tumor necrosis factor production
|
GO:0032720 |
20 |
0.018
|
|
|
|
viral entry into host cell
|
GO:0046718 |
24 |
0.018
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.018
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.018
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.018
|
|
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.018
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.018
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.018
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.018
|
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.018
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.018
|
|
|
|
protein trimerization
|
GO:0070206 |
20 |
0.018
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.018
|
|
|
|
negative regulation of cell projection organization
|
GO:0031345 |
22 |
0.018
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.018
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.018
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.018
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.018
|
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
1 |
0.018
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.017
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.017
|
|
|
|
peptidyl serine autophosphorylation
|
GO:0036289 |
2 |
0.017
|
|
|
|
negative regulation of calcium ion transport
|
GO:0051926 |
19 |
0.017
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.017
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.017
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.017
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.017
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.017
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.017
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
3 |
0.017
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.017
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.017
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.017
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.017
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.017
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.017
|
|
|
|
positive regulation of protein linear polyubiquitination
|
GO:1902530 |
2 |
0.017
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.017
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.017
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.017
|
|
|
|
entry into host cell
|
GO:0030260 |
25 |
0.016
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.016
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.016
|
|
|
|
cardiac endothelial cell differentiation
|
GO:0003348 |
2 |
0.016
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.016
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.016
|
|
|
|
regulation of protein polyubiquitination
|
GO:1902914 |
8 |
0.016
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.016
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.016
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.016
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.016
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.016
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.015
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.015
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.015
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.015
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.015
|
|
