|
|
protein sumoylation
|
GO:0016925 |
25 |
1.000
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
1.000
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
1.000
|
|
|
|
positive regulation of protein sumoylation
|
GO:0033235 |
7 |
1.000
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.999
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.999
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.998
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.997
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.995
|
|
|
|
regulation of protein sumoylation
|
GO:0033233 |
13 |
0.994
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.993
|
|
|
|
pml body organization
|
GO:0030578 |
2 |
0.990
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.990
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.988
|
Fly |
|
|
embryonic camera type eye morphogenesis
|
GO:0048596 |
2 |
0.987
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.986
|
Fly |
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.986
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.982
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.981
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.979
|
Fly |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.978
|
Rat |
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.975
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.965
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.965
|
Rat |
|
|
histone methylation
|
GO:0016571 |
60 |
0.964
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.957
|
Rat |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.957
|
|
|
|
definitive hemopoiesis
|
GO:0060216 |
2 |
0.955
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.954
|
Fly |
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.951
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.946
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.943
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.942
|
|
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.934
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.919
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.918
|
Worm |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.917
|
Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.917
|
|
|
|
retina layer formation
|
GO:0010842 |
3 |
0.915
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.914
|
Fly |
|
|
compound eye development
|
GO:0048749 |
1 |
0.913
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.908
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.903
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.901
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.900
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.899
|
Fly |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.897
|
Worm Fly |
|
|
embryo development
|
GO:0009790 |
123 |
0.893
|
Worm Fly |
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.892
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.877
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.865
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.860
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.856
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.855
|
Fly |
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.854
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.830
|
Rat |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.819
|
Rat |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.819
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.804
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.802
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.801
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.779
|
Fly |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.775
|
Rat |
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.774
|
|
|
|
viral release from host cell
|
GO:0019076 |
21 |
0.774
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.768
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.768
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.763
|
Fly |
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.758
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.755
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.753
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.740
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.728
|
Rat |
|
|
androgen receptor signaling pathway
|
GO:0030521 |
34 |
0.720
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.716
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.708
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
37 |
0.701
|
|
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.696
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.693
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.686
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.685
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.682
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.681
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.674
|
|
|
|
histone deacetylation
|
GO:0016575 |
32 |
0.674
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.671
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.669
|
Fly |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.654
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.650
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.640
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
0.640
|
|
|
|
nuclear export
|
GO:0051168 |
69 |
0.636
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.620
|
|
|
|
regulation of viral transcription
|
GO:0046782 |
34 |
0.620
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.612
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.606
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.597
|
Fly |
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.594
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.594
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.590
|
Fly |
|
|
central nervous system neuron development
|
GO:0021954 |
7 |
0.587
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.585
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.580
|
|
|
|
smad protein signal transduction
|
GO:0060395 |
10 |
0.576
|
|
|
|
regulation of membrane permeability
|
GO:0090559 |
25 |
0.566
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.562
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.561
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.552
|
|
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
2 |
0.549
|
|
|
|
regulation of cytokine mediated signaling pathway
|
GO:0001959 |
41 |
0.537
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.537
|
Fly |
|
|
protein methylation
|
GO:0006479 |
74 |
0.528
|
|
|
|
response to gamma radiation
|
GO:0010332 |
14 |
0.525
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.522
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.519
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.519
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.519
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.513
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.505
|
Rat |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.505
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.499
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.496
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.493
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.493
|
|
|
|
positive regulation of tooth mineralization
|
GO:0070172 |
2 |
0.492
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.486
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.482
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.471
|
Fly |
|
|
immune effector process
|
GO:0002252 |
159 |
0.471
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.470
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.469
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.469
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.468
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.462
|
Rat |
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.461
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.460
|
|
|
|
negative regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033144 |
18 |
0.456
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.456
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.455
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.453
|
|
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
2 |
0.451
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.449
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.441
|
Zebrafish Fly |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.439
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.437
|
Zebrafish |
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.437
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.436
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.429
|
|
|
|
growth
|
GO:0040007 |
202 |
0.427
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.425
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.421
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.413
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.407
|
Fly |
|
|
zymogen activation
|
GO:0031638 |
70 |
0.400
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.399
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.394
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.393
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.393
|
|
|
|
dna damage response signal transduction resulting in transcription
|
GO:0042772 |
12 |
0.392
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.392
|
|
|
|
dna packaging
|
GO:0006323 |
77 |
0.389
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.386
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.384
|
|
|
|
negative regulation of viral release from host cell
|
GO:1902187 |
12 |
0.381
|
|
|
|
regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033143 |
32 |
0.380
|
Rat |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.377
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.375
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.374
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.373
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
32 |
0.372
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.371
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.366
|
|
|
|
chromatin assembly
|
GO:0031497 |
61 |
0.366
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.365
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.363
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.363
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.362
|
|
|
|
negative regulation of myotube differentiation
|
GO:0010832 |
4 |
0.358
|
|
|
|
protein dna complex assembly
|
GO:0065004 |
64 |
0.354
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.351
|
|
|
|
central nervous system neuron axonogenesis
|
GO:0021955 |
3 |
0.348
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.341
|
|
|
|
negative regulation of chromatin modification
|
GO:1903309 |
21 |
0.341
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.334
|
|
|
|
viral gene expression
|
GO:0019080 |
35 |
0.331
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.328
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.322
|
Yeast |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.319
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.318
|
Fly |
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.315
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.312
|
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.312
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.308
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.302
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.302
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.302
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.297
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.296
|
Rat |
|
|
regulation of viral release from host cell
|
GO:1902186 |
20 |
0.293
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.291
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.291
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.290
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.290
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.289
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.288
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.286
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.276
|
Fly |
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.276
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.274
|
|
|
|
negative regulation of transcription by competitive promoter binding
|
GO:0010944 |
8 |
0.273
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.273
|
Fly |
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.272
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.269
|
|
|
|
protein deacylation
|
GO:0035601 |
39 |
0.267
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.265
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.264
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.263
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.263
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.261
|
Fly |
|
|
regulation of transcription involved in g2 m transition of mitotic cell cycle
|
GO:0000117 |
1 |
0.260
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.259
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.259
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.258
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.254
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.251
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.251
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.251
|
Rat |
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.249
|
Rat |
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.249
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.246
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.245
|
|
|
|
dna modification
|
GO:0006304 |
27 |
0.243
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.239
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.237
|
|
|
|
regulation of androgen receptor signaling pathway
|
GO:0060765 |
18 |
0.237
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.237
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
8 |
0.235
|
|
|
|
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:2000058 |
7 |
0.232
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.231
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.228
|
|
|
|
iris morphogenesis
|
GO:0061072 |
2 |
0.227
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.226
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.222
|
Worm |
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.222
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.222
|
|
|
|
response to toxic substance
|
GO:0009636 |
37 |
0.219
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.219
|
|
|
|
trophectodermal cell differentiation
|
GO:0001829 |
3 |
0.219
|
|
|
|
protein k11 linked ubiquitination
|
GO:0070979 |
24 |
0.219
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.218
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.216
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.216
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.216
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.213
|
|
|
|
regulation of muscle cell differentiation
|
GO:0051147 |
31 |
0.213
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.212
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.212
|
|
|
|
regulation of male gonad development
|
GO:2000018 |
4 |
0.212
|
|
|
|
regulation of lipid transport by regulation of transcription from rna polymerase ii promoter
|
GO:0072367 |
4 |
0.210
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.210
|
Fly |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.210
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.209
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.209
|
|
|
|
regulation of keratinocyte apoptotic process
|
GO:1902172 |
1 |
0.207
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.207
|
Worm Fly |
|
|
chromosome condensation
|
GO:0030261 |
15 |
0.206
|
|
|
|
lipid storage
|
GO:0019915 |
28 |
0.205
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.204
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.204
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.204
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.203
|
Fly |
|
|
common partner smad protein phosphorylation
|
GO:0007182 |
3 |
0.203
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.203
|
Fly |
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.203
|
|
|
|
positive regulation of apoptotic process involved in mammary gland involution
|
GO:0060058 |
1 |
0.202
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.199
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.195
|
|
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
38 |
0.195
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.195
|
|
|
|
head development
|
GO:0060322 |
108 |
0.195
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.193
|
|
|
|
positive regulation of odontogenesis
|
GO:0042482 |
3 |
0.193
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.192
|
|
|
|
multi organism metabolic process
|
GO:0044033 |
41 |
0.192
|
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
64 |
0.191
|
|
|
|
negative regulation of cytokine mediated signaling pathway
|
GO:0001960 |
22 |
0.190
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.190
|
Worm Fly |
|
|
regulation of b cell differentiation
|
GO:0045577 |
2 |
0.189
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.187
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.186
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.185
|
|
|
|
definitive erythrocyte differentiation
|
GO:0060318 |
2 |
0.184
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.184
|
|
|
|
rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0051123 |
4 |
0.183
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.183
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.182
|
|
|
|
positive regulation of apoptotic process involved in morphogenesis
|
GO:1902339 |
1 |
0.181
|
|
|
|
cell fate specification
|
GO:0001708 |
8 |
0.181
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.180
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.179
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.178
|
|
|
|
central nervous system projection neuron axonogenesis
|
GO:0021952 |
3 |
0.178
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.177
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.175
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.174
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.173
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.170
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.168
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.168
|
|
|
|
positive regulation of developmental growth
|
GO:0048639 |
16 |
0.168
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.165
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.165
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.165
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.164
|
|
|
|
negative regulation of androgen receptor signaling pathway
|
GO:0060766 |
10 |
0.163
|
|
|
|
camera type eye development
|
GO:0043010 |
25 |
0.162
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.160
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.159
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.158
|
|
|
|
positive regulation of male gonad development
|
GO:2000020 |
3 |
0.158
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.156
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.156
|
Fly |
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.156
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.155
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.155
|
Fly |
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.154
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.153
|
Fly |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.153
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.153
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.150
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.150
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.149
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
17 |
0.149
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.149
|
Worm |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.146
|
|
|
|
dna damage response detection of dna damage
|
GO:0042769 |
3 |
0.146
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.145
|
Rat |
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.145
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.144
|
Worm Fly |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.144
|
|
|
|
cartilage development involved in endochondral bone morphogenesis
|
GO:0060351 |
2 |
0.144
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.144
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.143
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.143
|
Worm |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.143
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.143
|
|
|
|
regulation of protein export from nucleus
|
GO:0046825 |
15 |
0.140
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.139
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.139
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.138
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.138
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.137
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.136
|
|
|
|
positive regulation of multicellular organism growth
|
GO:0040018 |
6 |
0.136
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.135
|
|
|
|
embryonic retina morphogenesis in camera type eye
|
GO:0060059 |
1 |
0.132
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.132
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.132
|
|
|
|
positive regulation of viral process
|
GO:0048524 |
37 |
0.131
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.130
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.128
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.128
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.127
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.127
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.127
|
|
|
|
bone development
|
GO:0060348 |
26 |
0.126
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.126
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
11 |
0.126
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.123
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.123
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.122
|
|
|
|
positive regulation of dna binding
|
GO:0043388 |
17 |
0.121
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.120
|
Worm |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.120
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.120
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.119
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.117
|
|
|
|
regulation of cell fate commitment
|
GO:0010453 |
7 |
0.117
|
|
|
|
positive regulation of binding
|
GO:0051099 |
45 |
0.116
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.115
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.115
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.114
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.114
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.114
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.113
|
|
|
|
positive regulation of histone modification
|
GO:0031058 |
29 |
0.112
|
|
|
|
regulation of interleukin 2 secretion
|
GO:1900040 |
2 |
0.112
|
|
|
|
regulation of gene silencing
|
GO:0060968 |
24 |
0.111
|
|
|
|
positive regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030511 |
12 |
0.109
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
68 |
0.108
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.108
|
Fly |
|
|
startle response
|
GO:0001964 |
3 |
0.108
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.108
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
9 |
0.108
|
Worm |
|
|
intracellular signal transduction involved in g1 dna damage checkpoint
|
GO:1902400 |
10 |
0.108
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.108
|
|
|
|
protein desumoylation
|
GO:0016926 |
4 |
0.107
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.106
|
|
|
|
positive regulation of mesenchymal stem cell differentiation
|
GO:2000741 |
4 |
0.105
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.104
|
Worm |
|
|
negative regulation of viral process
|
GO:0048525 |
66 |
0.104
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.104
|
|
|
|
protein export from nucleus
|
GO:0006611 |
29 |
0.102
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.102
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.102
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.100
|
|
|
|
nucleus organization
|
GO:0006997 |
28 |
0.100
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.100
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.100
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.100
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.099
|
|
|
|
regulation of mitochondrial membrane permeability
|
GO:0046902 |
25 |
0.099
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.097
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.096
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.095
|
|
|
|
endocrine system development
|
GO:0035270 |
26 |
0.093
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.092
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.092
|
|
|
|
regulation of protein acetylation
|
GO:1901983 |
25 |
0.092
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
33 |
0.092
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.092
|
|
|
|
cellular response to dsrna
|
GO:0071359 |
19 |
0.092
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.092
|
Worm |
|
|
sensory organ development
|
GO:0007423 |
52 |
0.091
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.091
|
|
|
|
positive regulation of neuron death
|
GO:1901216 |
14 |
0.089
|
|
|
|
mrna transcription
|
GO:0009299 |
8 |
0.089
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.089
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.088
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.088
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.088
|
Fly |
|
|
methylation dependent chromatin silencing
|
GO:0006346 |
3 |
0.087
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.087
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
80 |
0.086
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.085
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.085
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
54 |
0.084
|
|
|
|
fas signaling pathway
|
GO:0036337 |
3 |
0.084
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.084
|
|
|
|
regulation of schwann cell proliferation
|
GO:0010624 |
1 |
0.083
|
|
|
|
positive regulation of mammary gland involution
|
GO:1903521 |
1 |
0.082
|
|
|
|
positive regulation of response to dna damage stimulus
|
GO:2001022 |
43 |
0.082
|
|
|
|
negative regulation of dna binding
|
GO:0043392 |
18 |
0.082
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.081
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.081
|
|
|
|
circadian regulation of gene expression
|
GO:0032922 |
8 |
0.081
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.081
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
30 |
0.080
|
|
|
|
regulation of developmental pigmentation
|
GO:0048070 |
2 |
0.079
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
4 |
0.079
|
|
|
|
negative regulation of protein deubiquitination
|
GO:0090086 |
3 |
0.078
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
45 |
0.078
|
|
|
|
palate development
|
GO:0060021 |
13 |
0.078
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.077
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.076
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.076
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.075
|
Yeast |
|
|
camera type eye morphogenesis
|
GO:0048593 |
12 |
0.075
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.075
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.075
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.075
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.074
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.074
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.074
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.074
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.073
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.073
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.073
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.073
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.072
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.072
|
|
|
|
genetic imprinting
|
GO:0071514 |
1 |
0.072
|
|
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.072
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.072
|
|
|
|
endothelial cell apoptotic process
|
GO:0072577 |
26 |
0.071
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.071
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.071
|
|
|
|
mitochondrial fission
|
GO:0000266 |
14 |
0.070
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.070
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.069
|
|
|
|
cellular response to parathyroid hormone stimulus
|
GO:0071374 |
2 |
0.069
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.068
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.068
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
3 |
0.068
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.068
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.067
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.067
|
Worm Fly |
