|
|
protein ubiquitination
|
GO:0016567 |
314 |
1.000
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
1.000
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.999
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.996
|
Mouse Fly |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.962
|
Mouse Fly |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.950
|
Mouse Fly |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.948
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.947
|
Mouse Fly |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.939
|
Mouse Fly |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.917
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.916
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.784
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.774
|
Mouse Fly |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.757
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.741
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.738
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.722
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.721
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.692
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.691
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.662
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.656
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.649
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.645
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.641
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.630
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.628
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.590
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.582
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.582
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.578
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.542
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.486
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.479
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.470
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.467
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.450
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.446
|
Fly |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.408
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.408
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.407
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.406
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.389
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.388
|
|
|
|
growth
|
GO:0040007 |
202 |
0.372
|
Mouse |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.370
|
|
|
|
protein autoubiquitination
|
GO:0051865 |
37 |
0.357
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.356
|
Fly |
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.355
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.335
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.333
|
Fly |
|
|
dna repair
|
GO:0006281 |
198 |
0.327
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.321
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.311
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
45 |
0.292
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.282
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.252
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.249
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.230
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.228
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.217
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.215
|
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.215
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.207
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.206
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.200
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.196
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.188
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.186
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.185
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.184
|
Fly |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.181
|
Mouse Fly |
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.179
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.178
|
Fly |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.174
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.174
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.171
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.162
|
Fly |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.160
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.160
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.156
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.154
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.153
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.152
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.152
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.150
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.147
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.146
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.146
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.142
|
|
|
|
regulation of oxidative stress induced cell death
|
GO:1903201 |
24 |
0.141
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.140
|
|
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.139
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.136
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.136
|
Fly |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.132
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.131
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.130
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.129
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
0.128
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.122
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.120
|
|
|
|
positive regulation of ligase activity
|
GO:0051351 |
19 |
0.119
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.119
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.115
|
Fly |
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.115
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.114
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.109
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.104
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.101
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.100
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.094
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.094
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.093
|
|
|
|
regulation of response to oxidative stress
|
GO:1902882 |
26 |
0.093
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.092
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.090
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.089
|
Fly |
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.089
|
Fly |
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.087
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.087
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.087
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.086
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.082
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.080
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.080
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.078
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.077
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.077
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.077
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.076
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.076
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.076
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.076
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.076
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.075
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.075
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.075
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.074
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.074
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.071
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.070
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.069
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.069
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.068
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.068
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.067
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.067
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.067
|
Fly |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.066
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.065
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.063
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.063
|
|
|
|
histone h4 k12 acetylation
|
GO:0043983 |
6 |
0.061
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.060
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.057
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.057
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.057
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.055
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.055
|
|
|
|
negative regulation of autophagy
|
GO:0010507 |
14 |
0.054
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.053
|
Fly |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.052
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.052
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.051
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.051
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.050
|
Fly |
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.050
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.049
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
21 |
0.049
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.048
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.046
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.046
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
26 |
0.045
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.044
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.044
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.044
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.043
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.043
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.043
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.042
|
|
|
|
dna templated transcription elongation
|
GO:0006354 |
25 |
0.042
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.042
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.041
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.040
|
|
|
|
pallium development
|
GO:0021543 |
10 |
0.040
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.040
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.040
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.039
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.038
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.038
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.038
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.037
|
Fly |
|
|
protein k63 linked ubiquitination
|
GO:0070534 |
31 |
0.037
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.037
|
Fly |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.037
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.036
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.035
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.035
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.035
|
|
|
|
aging
|
GO:0007568 |
66 |
0.035
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.034
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.034
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.033
|
|
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
45 |
0.033
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.032
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.032
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.032
|
Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.032
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.032
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.032
|
Fly |
|
|
regulation of translation
|
GO:0006417 |
89 |
0.031
|
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
26 |
0.031
|
|
|
|
er associated ubiquitin dependent protein catabolic process
|
GO:0030433 |
31 |
0.031
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.031
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.031
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.030
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.030
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.030
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.030
|
Fly |
|
|
meiosis i
|
GO:0007127 |
4 |
0.029
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.029
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.029
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.029
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.029
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.029
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.029
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.029
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.029
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.028
|
|
|
|
response to topologically incorrect protein
|
GO:0035966 |
29 |
0.028
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.028
|
|
|
|
regulation of response to nutrient levels
|
GO:0032107 |
22 |
0.028
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.027
|
Mouse |
|
|
peptide transport
|
GO:0015833 |
74 |
0.027
|
|
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
6 |
0.027
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.027
|
|
|
|
vacuole organization
|
GO:0007033 |
44 |
0.027
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.027
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.027
|
|
|
|
histone h4 k5 acetylation
|
GO:0043981 |
15 |
0.026
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.026
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.026
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.026
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.026
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.025
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.025
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.025
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.025
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.025
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.024
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.024
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.024
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.024
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.024
|
|
|
|
regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902175 |
16 |
0.024
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.024
|
|
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.024
|
|
|
|
transcription elongation from rna polymerase ii promoter
|
GO:0006368 |
18 |
0.024
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.023
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.023
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.023
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.023
|
Fly |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.023
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.023
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.023
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.022
|
Fly |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.022
|
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.022
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.022
|
|
|
|
glycosylation
|
GO:0070085 |
71 |
0.022
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.022
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.022
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.022
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.021
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.021
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.021
|
|
|
|
central nervous system projection neuron axonogenesis
|
GO:0021952 |
3 |
0.021
|
|
|
|
regulation of autophagic vacuole assembly
|
GO:2000785 |
6 |
0.021
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.021
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.021
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.021
|
Fly |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.021
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.021
|
|
|
|
er nucleus signaling pathway
|
GO:0006984 |
23 |
0.021
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.020
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.020
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.020
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.020
|
|
|
|
response to gamma radiation
|
GO:0010332 |
14 |
0.020
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.019
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.019
|
|
|
|
regulation of macroautophagy
|
GO:0016241 |
19 |
0.019
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.019
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.019
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.019
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.019
|
|
|
|
negative regulation of epidermal growth factor receptor signaling pathway
|
GO:0042059 |
11 |
0.019
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.019
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.019
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.019
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.018
|
Mouse |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.018
|
|
|
|
male gamete generation
|
GO:0048232 |
22 |
0.018
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.018
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.018
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.018
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.018
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.018
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.018
|
Fly |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.018
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.017
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.017
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.017
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.017
|
|
|
|
protein k63 linked deubiquitination
|
GO:0070536 |
21 |
0.017
|
|
|
|
regulation of organelle assembly
|
GO:1902115 |
40 |
0.017
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.017
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.017
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.017
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.017
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.017
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.017
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.017
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.017
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.016
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.016
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.016
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.016
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.016
|
|
|
|
brain morphogenesis
|
GO:0048854 |
1 |
0.016
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.016
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.016
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.016
|
|
|
|
translation
|
GO:0006412 |
132 |
0.016
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.016
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.015
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.015
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.015
|
Mouse |
|
|
golgi vesicle transport
|
GO:0048193 |
80 |
0.015
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.015
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.015
|
|
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.015
|
|
|
|
positive regulation of response to dna damage stimulus
|
GO:2001022 |
43 |
0.015
|
|
|
|
negative regulation of transcription elongation from rna polymerase ii promoter
|
GO:0034244 |
4 |
0.015
|
|
|
|
response to salt stress
|
GO:0009651 |
3 |
0.015
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
32 |
0.015
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.015
|
Fly |
|
|
regulation of epidermal growth factor receptor signaling pathway
|
GO:0042058 |
27 |
0.015
|
|
|
|
negative regulation of response to dna damage stimulus
|
GO:2001021 |
33 |
0.015
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.015
|
Mouse |
|
|
histone h4 k8 acetylation
|
GO:0043982 |
15 |
0.015
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.015
|
Fly |
|
|
spermatid development
|
GO:0007286 |
4 |
0.014
|
|
|
|
protein glycosylation
|
GO:0006486 |
62 |
0.014
|
|
|
|
protein k48 linked deubiquitination
|
GO:0071108 |
19 |
0.014
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.014
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.014
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.014
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.014
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.014
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.014
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.014
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.014
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.014
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.014
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.014
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.014
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.014
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.014
|
Mouse |
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.014
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.014
|
|
|
|
negative regulation of cell morphogenesis involved in differentiation
|
GO:0010771 |
24 |
0.013
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.013
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.013
|
|
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
19 |
0.013
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.013
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.013
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.013
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.013
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.013
|
Mouse |
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.013
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.013
|
Fly |
|
|
establishment of monopolar cell polarity
|
GO:0061162 |
1 |
0.013
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.013
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.013
|
Mouse |
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
27 |
0.013
|
|
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.012
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.012
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.012
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.012
|
Mouse |
|
|
nuclear migration
|
GO:0007097 |
1 |
0.012
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.012
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
8 |
0.012
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.012
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.012
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.012
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.012
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.012
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.012
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.012
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.012
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.011
|
|
|
|
response to dietary excess
|
GO:0002021 |
2 |
0.011
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.011
|
Fly |
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.011
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.011
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.011
|
Mouse |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.011
|
|
|
|
organic acid catabolic process
|
GO:0016054 |
71 |
0.011
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.011
|
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.011
|
|
|
|
sleep
|
GO:0030431 |
2 |
0.011
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.011
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.011
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.011
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.011
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.011
|
|
|
|
outflow tract septum morphogenesis
|
GO:0003148 |
4 |
0.011
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.011
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.011
|
|
|
|
system process
|
GO:0003008 |
349 |
0.010
|
Fly |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.010
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.010
|
|
|
|
regulation of histone acetylation
|
GO:0035065 |
19 |
0.010
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.010
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.010
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.010
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.010
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.010
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.010
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.010
|
Mouse |