|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.972
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.949
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.875
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.820
|
Human |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.798
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.797
|
Fly |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.748
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.744
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.708
|
|
|
|
system process
|
GO:0003008 |
349 |
0.704
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.656
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.600
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.588
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.584
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.579
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.554
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.551
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.544
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.527
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.521
|
Human |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.511
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.485
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.474
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.458
|
Human |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.443
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.433
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.433
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.425
|
Fly |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.395
|
Human |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.383
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.381
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.364
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.360
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.359
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.357
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.355
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.353
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.349
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.331
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.322
|
|
|
|
memory
|
GO:0007613 |
3 |
0.321
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.321
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.306
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.293
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.292
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.286
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.281
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.275
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.274
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.272
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.261
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.249
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.248
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.243
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.239
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.237
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.236
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.235
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.231
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.230
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.219
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.207
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.207
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.207
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.205
|
Fly |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.202
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.197
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.196
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.195
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.194
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.192
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.187
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.186
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.182
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.182
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.182
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.181
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.180
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.178
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.175
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.174
|
Fly |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.174
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.174
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.171
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.171
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.169
|
Fly |
|
|
cognition
|
GO:0050890 |
43 |
0.168
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.167
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.166
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.165
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.160
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.159
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.158
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.157
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.156
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.149
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.146
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.143
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.141
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.140
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.139
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.137
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.137
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.136
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.134
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.133
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.131
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.131
|
Fly |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.130
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.129
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
54 |
0.128
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.120
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.120
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.118
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.117
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.116
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.116
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.115
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.113
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.113
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.112
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.112
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.112
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.111
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.110
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.108
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.107
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.106
|
Fly |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.106
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.105
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.105
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.104
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.100
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.100
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.097
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.096
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.096
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.096
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.096
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.095
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.093
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.093
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.093
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.093
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.092
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.091
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.091
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.090
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.090
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.090
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.089
|
Fly |
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.089
|
Fly |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.089
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.088
|
|
|
|
ribonucleoprotein complex assembly
|
GO:0022618 |
78 |
0.088
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.087
|
|
|
|
spindle organization
|
GO:0007051 |
53 |
0.086
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.085
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.085
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.083
|
Fly |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.082
|
|
|
|
transcription elongation from rna polymerase ii promoter
|
GO:0006368 |
18 |
0.082
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.080
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.079
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.079
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.079
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.078
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.077
|
Fly |
|
|
humoral immune response
|
GO:0006959 |
49 |
0.076
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.075
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.075
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.074
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.074
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.073
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.073
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.071
|
Fly |
|
|
central nervous system development
|
GO:0007417 |
123 |
0.071
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.071
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.070
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.068
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.068
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.068
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.067
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.066
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.066
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.065
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.064
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.063
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.063
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.063
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.063
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.063
|
Fly |
|
|
skeletal system development
|
GO:0001501 |
79 |
0.062
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.062
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.062
|
|
|
|
spermatogenesis
|
GO:0007283 |
22 |
0.062
|
Fly |
|
|
male gonad development
|
GO:0008584 |
23 |
0.060
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.060
|
|
|
|
regulation of rab protein signal transduction
|
GO:0032483 |
39 |
0.060
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.060
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.059
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.059
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.059
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.058
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.058
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.058
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.057
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.056
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.056
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.056
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.055
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.055
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.055
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.055
|
|
|
|
nucleobase containing compound transport
|
GO:0015931 |
51 |
0.055
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.054
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.054
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.054
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.054
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.053
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.053
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.053
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.053
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.053
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.053
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.052
|
|
|
|
nuclear export
|
GO:0051168 |
69 |
0.052
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.052
|
Fly |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.052
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.052
|
|
|
|
regulation of rab gtpase activity
|
GO:0032313 |
39 |
0.051
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.050
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.048
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.048
|
|
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.048
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.048
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.048
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.047
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.047
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.047
|
|
|
|
learning or memory
|
GO:0007611 |
13 |
0.047
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.046
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.046
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.046
|
|
|
|
positive regulation of rab gtpase activity
|
GO:0032851 |
39 |
0.046
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.046
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.046
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.046
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.046
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.044
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.044
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.044
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.043
|
|
|
|
sexual reproduction
|
GO:0019953 |
37 |
0.043
|
Fly |
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.043
|
|
|
|
male meiosis
|
GO:0007140 |
1 |
0.043
|
|
|
|
regulation of protein glycosylation
|
GO:0060049 |
6 |
0.042
|
|
|
|
male sex differentiation
|
GO:0046661 |
25 |
0.042
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.042
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.041
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.041
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.041
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.041
|
|
|
|
dna templated transcription elongation
|
GO:0006354 |
25 |
0.041
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.041
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.040
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.040
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.040
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.040
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.039
|
Fly |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.039
|
|
|
|
male gamete generation
|
GO:0048232 |
22 |
0.038
|
Fly |
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.038
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.038
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.038
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.037
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.037
|
Fly |
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.037
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.037
|
Fly |
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
47 |
0.037
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.036
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.036
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.035
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.035
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.034
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.034
|
|
|
|
translation
|
GO:0006412 |
132 |
0.034
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.033
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.033
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
11 |
0.033
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.033
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.033
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.033
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.033
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.033
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.032
|
|
|
|
head development
|
GO:0060322 |
108 |
0.032
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.032
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.032
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.032
|
|
|
|
forelimb morphogenesis
|
GO:0035136 |
4 |
0.032
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.032
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.031
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.031
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.031
|
|
|
|
adipose tissue development
|
GO:0060612 |
2 |
0.031
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.031
|
|
|
|
nuclear migration
|
GO:0007097 |
1 |
0.031
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.031
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.031
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.030
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.030
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.030
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.030
|
|
|
|
histone demethylation
|
GO:0016577 |
15 |
0.030
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.029
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.029
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.029
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
27 |
0.029
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.029
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.029
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.029
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.029
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.029
|
|
|
|
rna 3 end processing
|
GO:0031123 |
35 |
0.028
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.028
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.028
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.027
|
|
|
|
single organism behavior
|
GO:0044708 |
28 |
0.027
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.027
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.027
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.027
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.027
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.027
|
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.027
|
|
|
|
mitotic spindle organization
|
GO:0007052 |
27 |
0.026
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.026
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.026
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.026
|
Fly |
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.026
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.026
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.026
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
15 |
0.026
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.026
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.026
|
|
|
|
negative regulation of cell projection organization
|
GO:0031345 |
22 |
0.026
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.025
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.025
|
|
|
|
protein deacylation
|
GO:0035601 |
39 |
0.025
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
3 |
0.025
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.025
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.025
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.025
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.024
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.024
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.024
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.024
|
|
|
|
response to peptide
|
GO:1901652 |
65 |
0.024
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.024
|
|
|
|
regulation of transcription elongation from rna polymerase ii promoter
|
GO:0034243 |
13 |
0.024
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.023
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.023
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.023
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.023
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.023
|
|
|
|
centrosome organization
|
GO:0051297 |
58 |
0.023
|
|
|
|
regulation of dna templated transcription elongation
|
GO:0032784 |
23 |
0.023
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.023
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
24 |
0.022
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.022
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.022
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.022
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.022
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.022
|
|
|
|
nuclear transcribed mrna catabolic process
|
GO:0000956 |
48 |
0.022
|
|
|
|
mrna processing
|
GO:0006397 |
133 |
0.022
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.022
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.022
|
|
|
|
rna catabolic process
|
GO:0006401 |
71 |
0.022
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.022
|
|
|
|
negative regulation of translation
|
GO:0017148 |
37 |
0.022
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.021
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.021
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.021
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.021
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.021
|
|
|
|
glycosylation
|
GO:0070085 |
71 |
0.021
|
|
|
|
positive regulation of developmental growth
|
GO:0048639 |
16 |
0.021
|
|
|
|
aging
|
GO:0007568 |
66 |
0.021
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.021
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.021
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.021
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.021
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.021
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.021
|
|
|
|
short term memory
|
GO:0007614 |
1 |
0.021
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.021
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.021
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.021
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.021
|
Human |
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.021
|
|
|
|
growth
|
GO:0040007 |
202 |
0.021
|
Fly |
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.020
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.020
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.020
|
Human |
|
|
dna biosynthetic process
|
GO:0071897 |
40 |
0.020
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
8 |
0.020
|
Fly |
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.020
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.020
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
27 |
0.020
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.020
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.020
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.020
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.019
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.019
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.019
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.019
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.019
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.019
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
45 |
0.019
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.019
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.019
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.019
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.019
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.019
|
|
|
|
regulation of organelle assembly
|
GO:1902115 |
40 |
0.019
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.019
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.019
|
|
|
|
mrna catabolic process
|
GO:0006402 |
56 |
0.019
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.019
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.019
|
|
|
|
glucose metabolic process
|
GO:0006006 |
45 |
0.019
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.018
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.018
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.018
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.018
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.018
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.018
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.018
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.018
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.018
|
|
|
|
regulation of glycoprotein biosynthetic process
|
GO:0010559 |
14 |
0.018
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.018
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.018
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.017
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.017
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.017
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.017
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.017
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.016
|
|
|
|
fat cell differentiation
|
GO:0045444 |
32 |
0.016
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.016
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.016
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.016
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.016
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.016
|
Fly |
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
46 |
0.016
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.016
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.016
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.016
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.016
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.016
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.016
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.015
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.015
|
|
|
|
protein monoubiquitination
|
GO:0006513 |
39 |
0.015
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.015
|
|
|
|
centrosome cycle
|
GO:0007098 |
32 |
0.015
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
44 |
0.015
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.015
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.015
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
41 |
0.015
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.015
|
|
|
|
multicellular organism growth
|
GO:0035264 |
8 |
0.015
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.015
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.015
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.015
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.014
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.014
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.014
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.014
|
|
|
|
spindle elongation
|
GO:0051231 |
4 |
0.014
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.014
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.014
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.014
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.014
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.014
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.014
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.014
|
|
