Homo sapiens

69 known processes

UCHL5

ubiquitin carboxyl-terminal hydrolase L5

(Aliases: UCH37,INO80R,UCH-L5,CGI-70)

UCHL5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to dna damage stimulus GO:0006974 379 0.982
dna repair GO:0006281 198 0.958
proteasomal protein catabolic process GO:0010498 176 0.927
cellular macromolecular complex assembly GO:0034622 324 0.886
modification dependent protein catabolic process GO:0019941 209 0.874
chromatin organization GO:0006325 351 0.863
Human
post embryonic development GO:0009791 2 0.793
Worm
multicellular organismal aging GO:0010259 3 0.758
Worm
regulation of peptidase activity GO:0052547 180 0.756
determination of adult lifespan GO:0008340 2 0.732
Worm
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.728
positive regulation of peptidase activity GO:0010952 88 0.689
microtubule cytoskeleton organization GO:0000226 176 0.645
protein catabolic process GO:0030163 325 0.609
chromatin modification GO:0016568 298 0.426
Human
cellular protein catabolic process GO:0044257 261 0.365
mitotic nuclear division GO:0007067 119 0.335
cellular protein complex assembly GO:0043623 188 0.330
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.329
regulation of proteolysis GO:0030162 293 0.328
cellular macromolecule catabolic process GO:0044265 380 0.303
nuclear division GO:0000280 128 0.294
nucleoside monophosphate metabolic process GO:0009123 191 0.290
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.270
chromatin remodeling GO:0006338 55 0.254
purine nucleoside triphosphate catabolic process GO:0009146 392 0.239
modification dependent macromolecule catabolic process GO:0043632 212 0.237
nucleoside phosphate catabolic process GO:1901292 412 0.217
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 4 0.216
purine nucleoside monophosphate catabolic process GO:0009128 158 0.197
mitotic cell cycle process GO:1903047 286 0.196
glycosyl compound catabolic process GO:1901658 413 0.185
positive regulation of endopeptidase activity GO:0010950 84 0.180
reproduction GO:0000003 63 0.177
mitotic sister chromatid segregation GO:0000070 53 0.166
organelle fission GO:0048285 149 0.161
proteasome regulatory particle assembly GO:0070682 2 0.161
chromosome segregation GO:0007059 114 0.155
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.151
negative regulation of cell death GO:0060548 345 0.150
rna interference GO:0016246 4 0.148
proteasome assembly GO:0043248 7 0.140
ribonucleoside monophosphate catabolic process GO:0009158 158 0.140
regulation of proteasomal protein catabolic process GO:0061136 87 0.138
purine nucleoside monophosphate metabolic process GO:0009126 186 0.128
blastocyst development GO:0001824 3 0.124
ubiquitin dependent protein catabolic process GO:0006511 206 0.113
protein dna complex subunit organization GO:0071824 80 0.109
regulation of protein ubiquitination GO:0031396 95 0.105
mitotic cell cycle GO:0000278 326 0.104
apoptotic signaling pathway GO:0097190 268 0.103
purine ribonucleoside catabolic process GO:0046130 398 0.103
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.102
spermatid differentiation GO:0048515 4 0.101
embryo development GO:0009790 123 0.098
Worm
oogenesis GO:0048477 2 0.088
purine nucleoside catabolic process GO:0006152 398 0.086
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 4 0.086
nucleoside monophosphate catabolic process GO:0009125 159 0.081
double strand break repair GO:0006302 101 0.077
atp catabolic process GO:0006200 157 0.076
multicellular organism reproduction GO:0032504 42 0.075
embryo development ending in birth or egg hatching GO:0009792 34 0.074
Worm
ribonucleoside catabolic process GO:0042454 406 0.072
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.065
purine ribonucleotide catabolic process GO:0009154 404 0.064
female gamete generation GO:0007292 2 0.060
protein secretion GO:0009306 98 0.058
transcriptional activation by promoter enhancer looping GO:0071733 1 0.051
nucleotide catabolic process GO:0009166 408 0.048
regulation of protein complex assembly GO:0043254 147 0.047
regulation of cell cycle process GO:0010564 266 0.043
secretion by cell GO:0032940 226 0.041
purine containing compound catabolic process GO:0072523 411 0.040
regulation of cellular component biogenesis GO:0044087 281 0.040
purine nucleotide catabolic process GO:0006195 405 0.040
sister chromatid segregation GO:0000819 54 0.039
purine ribonucleoside metabolic process GO:0046128 437 0.039
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.038
covalent chromatin modification GO:0016569 254 0.038
Human
organophosphate catabolic process GO:0046434 430 0.038
negative regulation of cellular protein metabolic process GO:0032269 353 0.037
atp metabolic process GO:0046034 176 0.036
nucleoside triphosphate catabolic process GO:0009143 394 0.036
aging GO:0007568 66 0.034
Worm
regulation of gene expression epigenetic GO:0040029 73 0.034
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.033
protein modification by small protein conjugation GO:0032446 342 0.032
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.028
regulation of cellular protein catabolic process GO:1903362 96 0.028
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.028
regulation of defense response GO:0031347 154 0.026
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
posttranscriptional gene silencing GO:0016441 25 0.026
nucleoside catabolic process GO:0009164 408 0.025
gene silencing GO:0016458 49 0.024
negative regulation of protein processing GO:0010955 142 0.024
mitotic cell cycle phase transition GO:0044772 162 0.023
ribonucleotide catabolic process GO:0009261 405 0.023
cellular response to oxidative stress GO:0034599 85 0.022
cell division GO:0051301 168 0.022
ribosomal small subunit export from nucleus GO:0000056 3 0.021
regulation of cellular amino acid metabolic process GO:0006521 6 0.021
ribonucleoside triphosphate catabolic process GO:0009203 391 0.020
anatomical structure homeostasis GO:0060249 100 0.020
histone h4 acetylation GO:0043967 47 0.019
ribonucleoside triphosphate metabolic process GO:0009199 412 0.019
posttranscriptional regulation of gene expression GO:0010608 213 0.019
histone exchange GO:0043486 3 0.019
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 25 0.018
microtubule based process GO:0007017 210 0.018
proteasomal ubiquitin independent protein catabolic process GO:0010499 3 0.018
regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:1902165 7 0.018
purine nucleoside triphosphate metabolic process GO:0009144 412 0.017
regulation of mitotic cell cycle GO:0007346 189 0.017
positive regulation of proteolysis GO:0045862 142 0.017
positive regulation of mitochondrial membrane potential GO:0010918 1 0.017
defense response GO:0006952 315 0.016
positive regulation of hydrolase activity GO:0051345 331 0.016
reproductive process GO:0022414 106 0.016
gene looping GO:0090202 1 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
pyrimidine nucleoside monophosphate metabolic process GO:0009129 1 0.014
regulation of mitotic recombination GO:0000019 1 0.014
regulation of apoptotic signaling pathway GO:2001233 175 0.014
dsdna loop formation GO:0090579 1 0.014
regulation of cell division GO:0051302 116 0.014
nucleoside triphosphate metabolic process GO:0009141 422 0.013
secretion GO:0046903 254 0.013
dna conformation change GO:0071103 113 0.013
chromosome separation GO:0051304 23 0.013
regulation of histone h4 k16 acetylation GO:2000618 1 0.013
snrna modification GO:0040031 1 0.013
posttranscriptional gene silencing by rna GO:0035194 25 0.013
establishment of protein localization to organelle GO:0072594 172 0.012
meiotic chromosome segregation GO:0045132 4 0.012
regulation of cell cycle GO:0051726 393 0.012
Human
cellular ketone metabolic process GO:0042180 80 0.012
single organism reproductive process GO:0044702 98 0.011
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.011
regulation of protein catabolic process GO:0042176 155 0.011
cenp a containing chromatin organization GO:0061641 1 0.011
gonad development GO:0008406 34 0.011
positive regulation of cellular component organization GO:0051130 376 0.011
ribosome assembly GO:0042255 9 0.011
protein maturation GO:0051604 233 0.011
spermatid development GO:0007286 4 0.011
positive regulation of protein complex assembly GO:0031334 86 0.011
negative regulation of endopeptidase activity GO:0010951 84 0.010
cell growth GO:0016049 160 0.010
Human
dna packaging GO:0006323 77 0.010

UCHL5 disease predictions

Disease DO term ID Size Probability Func Analog Org
skin disease DOID:37 33 0.011
integumentary system disease DOID:16 43 0.011
lynch syndrome DOID:3883 3 0.011
endocrine system disease DOID:28 26 0.010