|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.983
|
Human |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.953
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.951
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.947
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.945
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.933
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.914
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.893
|
|
|
|
negative regulation of mitotic anaphase promoting complex activity
|
GO:0060564 |
4 |
0.886
|
|
|
|
neutral lipid catabolic process
|
GO:0046461 |
12 |
0.876
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.835
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.815
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.814
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.801
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.782
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.745
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.742
|
|
|
|
triglyceride catabolic process
|
GO:0019433 |
10 |
0.742
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.732
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.702
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.700
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.687
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.668
|
Human |
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.623
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.621
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.601
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.595
|
Human |
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.586
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.584
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.573
|
|
|
|
negative regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0071930 |
2 |
0.568
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.565
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.565
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.563
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.560
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.544
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.541
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.524
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.521
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.511
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.508
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.492
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.470
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.469
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.468
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.467
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.457
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.456
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.451
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.441
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.440
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.437
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.422
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.420
|
|
|
|
negative regulation of cell cycle arrest
|
GO:0071157 |
12 |
0.410
|
|
|
|
regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0000083 |
8 |
0.405
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.405
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.401
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.399
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.387
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.379
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.378
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.374
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.360
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.359
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.358
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.354
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.354
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.354
|
|
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
21 |
0.353
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.352
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.350
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.343
|
|
|
|
growth
|
GO:0040007 |
202 |
0.341
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.335
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.335
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.334
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.332
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.331
|
|
|
|
dna damage response signal transduction resulting in transcription
|
GO:0042772 |
12 |
0.321
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.320
|
Human |
|
|
protein processing
|
GO:0016485 |
226 |
0.312
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.310
|
|
|
|
autophagic cell death
|
GO:0048102 |
3 |
0.305
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.304
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.304
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.302
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.300
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.294
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.293
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.292
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.287
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.286
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.285
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.284
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
33 |
0.282
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.282
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.281
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.281
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.280
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.279
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.276
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.273
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.270
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.268
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.267
|
|
|
|
mitotic g1 s transition checkpoint
|
GO:0044819 |
17 |
0.265
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.263
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.263
|
|
|
|
positive regulation of triglyceride metabolic process
|
GO:0090208 |
9 |
0.258
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.258
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.256
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.253
|
|
|
|
type b pancreatic cell development
|
GO:0003323 |
4 |
0.251
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.251
|
|
|
|
phosphorylation of rna polymerase ii c terminal domain
|
GO:0070816 |
3 |
0.246
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.242
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.237
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.237
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
19 |
0.234
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.234
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.234
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.233
|
|
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
0.233
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.231
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.226
|
|
|
|
metanephros development
|
GO:0001656 |
16 |
0.222
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.221
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.221
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.220
|
|
|
|
negative regulation of mitotic metaphase anaphase transition
|
GO:0045841 |
17 |
0.219
|
|
|
|
protein deacylation
|
GO:0035601 |
39 |
0.218
|
|
|
|
response to toxic substance
|
GO:0009636 |
37 |
0.218
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.215
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.214
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.212
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.210
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.209
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
45 |
0.208
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.207
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.207
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.203
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.201
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.201
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.201
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.200
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.194
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.194
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.194
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.193
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.190
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.188
|
|
|
|
negative regulation of ubiquitin protein transferase activity
|
GO:0051444 |
8 |
0.187
|
|
|
|
negative regulation of ligase activity
|
GO:0051352 |
8 |
0.186
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.184
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
32 |
0.184
|
|
|
|
endocrine system development
|
GO:0035270 |
26 |
0.184
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.184
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.184
|
|
|
|
double strand break repair via homologous recombination
|
GO:0000724 |
50 |
0.183
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.182
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.182
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.182
|
|
|
|
male sex differentiation
|
GO:0046661 |
25 |
0.180
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.180
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.179
|
|
|
|
response to camp
|
GO:0051591 |
25 |
0.175
|
|
|
|
rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0051123 |
4 |
0.174
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.173
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.173
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.170
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.170
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.168
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.167
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.166
|
|
|
|
hematopoietic stem cell differentiation
|
GO:0060218 |
4 |
0.166
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.165
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.165
|
|
|
|
hepaticobiliary system development
|
GO:0061008 |
10 |
0.164
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.163
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.162
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.161
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.161
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.161
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.161
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.159
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.157
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.157
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.156
|
|
|
|
er nucleus signaling pathway
|
GO:0006984 |
23 |
0.155
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.154
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.154
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.153
|
|
|
|
cellular response to lithium ion
|
GO:0071285 |
2 |
0.153
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.152
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.151
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.150
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.150
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.149
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.148
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.148
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.148
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.147
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.144
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.143
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.143
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.142
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.141
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.139
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.135
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.135
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.133
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.133
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.132
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.132
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.131
|
|
|
|
regulation of metaphase anaphase transition of cell cycle
|
GO:1902099 |
26 |
0.131
|
|
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
27 |
0.131
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.130
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
32 |
0.128
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.126
|
|
|
|
positive regulation of response to dna damage stimulus
|
GO:2001022 |
43 |
0.125
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.124
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.124
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.123
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.123
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.123
|
|
|
|
response to lithium ion
|
GO:0010226 |
2 |
0.122
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.122
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.120
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.120
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.120
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.120
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.119
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
21 |
0.118
|
|
|
|
regulation of double strand break repair
|
GO:2000779 |
22 |
0.117
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.117
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.117
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.117
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
29 |
0.115
|
|
|
|
ureteric bud development
|
GO:0001657 |
13 |
0.114
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.114
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.112
|
|
|
|
dna replication initiation
|
GO:0006270 |
6 |
0.112
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.111
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.110
|
|
|
|
signal transduction involved in mitotic cell cycle checkpoint
|
GO:0072413 |
13 |
0.109
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.109
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.109
|
|
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
17 |
0.109
|
|
|
|
response to transition metal nanoparticle
|
GO:1990267 |
29 |
0.108
|
|
|
|
intracellular signal transduction involved in g1 dna damage checkpoint
|
GO:1902400 |
10 |
0.107
|
|
|
|
male gonad development
|
GO:0008584 |
23 |
0.107
|
|
|
|
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle
|
GO:0051436 |
4 |
0.106
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.104
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.104
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.104
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.104
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.103
|
|
|
|
glycerolipid catabolic process
|
GO:0046503 |
18 |
0.103
|
|
|
|
signal transduction involved in mitotic dna integrity checkpoint
|
GO:1902403 |
13 |
0.102
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.101
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
13 |
0.101
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.101
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.101
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.100
|
|
|
|
cell cycle dna replication
|
GO:0044786 |
11 |
0.100
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.099
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.099
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.098
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.098
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.098
|
|
|
|
enteroendocrine cell differentiation
|
GO:0035883 |
6 |
0.097
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.097
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.096
|
|
|
|
positive regulation of g2 m transition of mitotic cell cycle
|
GO:0010971 |
8 |
0.095
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.094
|
|
|
|
positive regulation of dna repair
|
GO:0045739 |
25 |
0.092
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
23 |
0.092
|
|
|
|
cartilage condensation
|
GO:0001502 |
1 |
0.091
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.090
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest
|
GO:0006977 |
9 |
0.089
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.089
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.089
|
|
|
|
cohesin localization to chromatin
|
GO:0071921 |
4 |
0.089
|
|
|
|
mitotic cell cycle arrest
|
GO:0071850 |
4 |
0.089
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.089
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.089
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.089
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.089
|
|
|
|
prostate gland development
|
GO:0030850 |
3 |
0.088
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.087
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.086
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.086
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.086
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.085
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.085
|
|
|
|
response to magnesium ion
|
GO:0032026 |
3 |
0.084
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.084
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.083
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.083
|
|
|
|
positive regulation of dendrite morphogenesis
|
GO:0050775 |
3 |
0.083
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.082
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.082
|
|
|
|
liver development
|
GO:0001889 |
9 |
0.082
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.082
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.081
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.081
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.080
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.079
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.079
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.078
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.078
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.078
|
|
|
|
glandular epithelial cell development
|
GO:0002068 |
5 |
0.077
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.077
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.077
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.077
|
|
|
|
dna synthesis involved in dna repair
|
GO:0000731 |
6 |
0.077
|
|
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.077
|
|
|
|
signal transduction involved in mitotic g1 dna damage checkpoint
|
GO:0072431 |
10 |
0.077
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.076
|
|
|
|
histone h3 k9 modification
|
GO:0061647 |
11 |
0.076
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.075
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.074
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.074
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.074
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.074
|
|
|
|
regulation of mitotic metaphase anaphase transition
|
GO:0030071 |
26 |
0.073
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.073
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.073
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.073
|
|
|
|
negative regulation of mitosis
|
GO:0045839 |
24 |
0.073
|
|
|
|
regulation of cell diameter
|
GO:0060305 |
1 |
0.073
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.073
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.072
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.072
|
|
|
|
recombinational repair
|
GO:0000725 |
50 |
0.071
|
|
|
|
neutral lipid metabolic process
|
GO:0006638 |
27 |
0.071
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.071
|
|
|
|
regulation of cell cycle g2 m phase transition
|
GO:1902749 |
22 |
0.070
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.070
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.070
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.069
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.069
|
|
|
|
nephron epithelium development
|
GO:0072009 |
23 |
0.069
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.068
|
|
|
|
dna biosynthetic process
|
GO:0071897 |
40 |
0.068
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.067
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.067
|
|
|
|
system process
|
GO:0003008 |
349 |
0.066
|
|
|
|
negative regulation of mitotic sister chromatid separation
|
GO:2000816 |
17 |
0.066
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.066
|
|
|
|
negative regulation of epithelial cell differentiation
|
GO:0030857 |
6 |
0.065
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.065
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.064
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.064
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.064
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.064
|
|
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
16 |
0.064
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.063
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.062
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.062
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.062
|
|
|
|
camera type eye development
|
GO:0043010 |
25 |
0.062
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.062
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.062
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.061
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.061
|
|
|
|
regulation of g2 m transition of mitotic cell cycle
|
GO:0010389 |
20 |
0.061
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.061
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.061
|
|
|
|
negative regulation of axonogenesis
|
GO:0050771 |
4 |
0.061
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.060
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.060
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.059
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.059
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.059
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.058
|
|
|
|
negative regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045736 |
15 |
0.058
|
|
|
|
chromatin mediated maintenance of transcription
|
GO:0048096 |
2 |
0.057
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.057
|
|
|
|
sensory perception of sound
|
GO:0007605 |
37 |
0.057
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.057
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.056
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.056
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.056
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.056
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.055
|
|
|
|
regulation of mitotic sister chromatid segregation
|
GO:0033047 |
27 |
0.055
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.055
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.055
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.055
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.054
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.054
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.054
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.054
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.054
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.054
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.054
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.053
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.053
|
|
|
|
metaphase anaphase transition of mitotic cell cycle
|
GO:0007091 |
21 |
0.053
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.052
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.052
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.052
|
|
|
|
chromosome separation
|
GO:0051304 |
23 |
0.052
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.051
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.051
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.051
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.050
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.050
|
|
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.050
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.050
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.050
|
|
|
|
triglyceride metabolic process
|
GO:0006641 |
23 |
0.050
|
|
|
|
positive regulation of cardiac muscle cell proliferation
|
GO:0060045 |
2 |
0.050
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.050
|
|
|
|
positive regulation of mitotic cell cycle phase transition
|
GO:1901992 |
19 |
0.050
|
|
|
|
g2 dna damage checkpoint
|
GO:0031572 |
26 |
0.050
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.049
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.049
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.049
|
|
|
|
glomerular epithelial cell development
|
GO:0072310 |
3 |
0.049
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.048
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.048
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.048
|
|
|
|
histone threonine phosphorylation
|
GO:0035405 |
7 |
0.048
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.048
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.048
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.047
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.047
|
|
|
|
lung epithelial cell differentiation
|
GO:0060487 |
1 |
0.047
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.047
|
|
|
|
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031145 |
25 |
0.047
|
|
|
|
regulation of sister chromatid cohesion
|
GO:0007063 |
9 |
0.047
|
|
|
|
cellular response to toxic substance
|
GO:0097237 |
4 |
0.047
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.046
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.046
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.046
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.046
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.046
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.046
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.045
|
|
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
3 |
0.044
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.044
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.044
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
18 |
0.044
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.043
|
|
|
|
response to topologically incorrect protein
|
GO:0035966 |
29 |
0.043
|
|
|
|
lactation
|
GO:0007595 |
3 |
0.043
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.043
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.043
|
|
|
|
oocyte maturation
|
GO:0001556 |
1 |
0.042
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.042
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.042
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.042
|
|
|
|
negative regulation of transcription by competitive promoter binding
|
GO:0010944 |
8 |
0.042
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.042
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.041
|
|
|
|
male meiosis
|
GO:0007140 |
1 |
0.041
|
|
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.041
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.041
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.041
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.041
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.041
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.041
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.041
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
10 |
0.041
|
|
|
|
acylglycerol metabolic process
|
GO:0006639 |
27 |
0.041
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.040
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.040
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.040
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.040
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.040
|
|
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
19 |
0.039
|
|
|
|
viral gene expression
|
GO:0019080 |
35 |
0.039
|
|
|
|
mitotic sister chromatid separation
|
GO:0051306 |
18 |
0.039
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.039
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.039
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.038
|
|
|
|
negative regulation of proteasomal protein catabolic process
|
GO:1901799 |
32 |
0.038
|
|
|
|
negative regulation of viral process
|
GO:0048525 |
66 |
0.038
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.038
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.038
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.038
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.038
|
|
|
|
regulation of cardiac muscle tissue growth
|
GO:0055021 |
4 |
0.038
|
|
