Homo sapiens

17 known processes

USP11

ubiquitin specific peptidase 11

(Aliases: UHX1)

USP11 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
segmentation GO:0035282 4 0.999
histone monoubiquitination GO:0010390 20 0.995
histone h2a monoubiquitination GO:0035518 11 0.993
protein modification by small protein conjugation GO:0032446 342 0.988
Human
blastoderm segmentation GO:0007350 2 0.980
neuron remodeling GO:0016322 2 0.978
histone h2a ubiquitination GO:0033522 17 0.969
histone ubiquitination GO:0016574 31 0.846
response to radiation GO:0009314 151 0.800
regulation of axon guidance GO:1902667 3 0.782
response to ionizing radiation GO:0010212 65 0.774
nervous system development GO:0007399 293 0.697
regulation of ligase activity GO:0051340 29 0.679
anterior posterior axis specification GO:0009948 2 0.661
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.579
generation of neurons GO:0048699 152 0.578
wound healing GO:0042060 115 0.529
mitotic cell cycle GO:0000278 326 0.525
sebaceous gland development GO:0048733 1 0.510
regionalization GO:0003002 29 0.492
gene silencing GO:0016458 49 0.473
neurogenesis GO:0022008 169 0.471
response to wounding GO:0009611 168 0.451
response to oxygen containing compound GO:1901700 369 0.442
protein ubiquitination GO:0016567 314 0.435
Human
response to gamma radiation GO:0010332 14 0.429
fibroblast proliferation GO:0048144 33 0.417
neuron differentiation GO:0030182 138 0.411
regulation of axon extension involved in axon guidance GO:0048841 2 0.400
neuron maturation GO:0042551 5 0.377
response to abiotic stimulus GO:0009628 336 0.360
Human
regulation of transferase activity GO:0051338 355 0.331
neuron projection development GO:0031175 106 0.329
spinal cord development GO:0021510 4 0.322
response to inorganic substance GO:0010035 127 0.317
cell development GO:0048468 328 0.309
regulation of ubiquitin protein transferase activity GO:0051438 28 0.293
positive regulation of transferase activity GO:0051347 227 0.259
neuron development GO:0048666 113 0.257
skeletal system morphogenesis GO:0048705 24 0.248
pattern specification process GO:0007389 43 0.236
negative regulation of cell death GO:0060548 345 0.232
developmental maturation GO:0021700 28 0.227
negative regulation of apoptotic signaling pathway GO:2001234 97 0.219
embryo development GO:0009790 123 0.212
protein monoubiquitination GO:0006513 39 0.212
axon extension involved in axon guidance GO:0048846 5 0.203
skeletal system development GO:0001501 79 0.198
regulation of cell projection organization GO:0031344 107 0.190
chromatin organization GO:0006325 351 0.190
cell projection organization GO:0030030 252 0.188
chromatin modification GO:0016568 298 0.185
regulation of gene expression epigenetic GO:0040029 73 0.180
internal peptidyl lysine acetylation GO:0018393 97 0.172
cell morphogenesis GO:0000902 296 0.161
positive regulation of fibroblast proliferation GO:0048146 21 0.155
post embryonic development GO:0009791 2 0.152
cellular response to oxidative stress GO:0034599 85 0.146
tube development GO:0035295 125 0.121
protein deubiquitination GO:0016579 79 0.111
negative regulation of programmed cell death GO:0043069 321 0.104
response to hydrogen peroxide GO:0042542 40 0.102
positive regulation of ubiquitin protein transferase activity GO:0051443 18 0.095
regulation of neuron differentiation GO:0045664 70 0.094
positive regulation of ligase activity GO:0051351 19 0.091
regulation of behavior GO:0050795 82 0.090
protein acetylation GO:0006473 116 0.089
peptidyl lysine acetylation GO:0018394 101 0.085
regulation of neurogenesis GO:0050767 82 0.083
cell morphogenesis involved in differentiation GO:0000904 144 0.082
embryonic morphogenesis GO:0048598 85 0.079
apoptotic signaling pathway GO:0097190 268 0.077
response to oxidative stress GO:0006979 121 0.076
cellular component morphogenesis GO:0032989 314 0.076
embryonic organ morphogenesis GO:0048562 24 0.073
locomotory behavior GO:0007626 1 0.069
proteasomal protein catabolic process GO:0010498 176 0.069
Human
camera type eye development GO:0043010 25 0.069
covalent chromatin modification GO:0016569 254 0.069
regulation of apoptotic signaling pathway GO:2001233 175 0.069
cell projection morphogenesis GO:0048858 129 0.068
histone modification GO:0016570 251 0.068
negative regulation of apoptotic process GO:0043066 316 0.068
guanosine containing compound catabolic process GO:1901069 239 0.066
intrinsic apoptotic signaling pathway GO:0097193 127 0.063
immune system development GO:0002520 195 0.062
embryonic pattern specification GO:0009880 5 0.061
neuron projection morphogenesis GO:0048812 50 0.060
cellular amino acid metabolic process GO:0006520 116 0.060
purine ribonucleoside metabolic process GO:0046128 437 0.059
organ morphogenesis GO:0009887 147 0.058
regulation of cell cycle process GO:0010564 266 0.057
small gtpase mediated signal transduction GO:0007264 78 0.057
reproductive process GO:0022414 106 0.056
axon extension GO:0048675 13 0.056
enzyme linked receptor protein signaling pathway GO:0007167 303 0.055
Human
regulation of cellular amino acid metabolic process GO:0006521 6 0.055
chromatin silencing GO:0006342 12 0.053
cellular macromolecule catabolic process GO:0044265 380 0.052
Human
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.052
neuromuscular junction development GO:0007528 3 0.051
hemopoiesis GO:0030097 180 0.050
negative regulation of gene expression epigenetic GO:0045814 19 0.048
axon development GO:0061564 34 0.047
vesicle mediated transport GO:0016192 371 0.047
regulation of purine nucleotide metabolic process GO:1900542 264 0.047
hematopoietic or lymphoid organ development GO:0048534 186 0.047
development of primary sexual characteristics GO:0045137 35 0.047
response to organic cyclic compound GO:0014070 204 0.045
single organism cellular localization GO:1902580 332 0.045
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.045
Human
positive regulation of synaptic transmission GO:0050806 4 0.043
nucleocytoplasmic transport GO:0006913 176 0.043
regulation of extent of cell growth GO:0061387 9 0.043
t cell differentiation in thymus GO:0033077 4 0.043
regulation of gtpase activity GO:0043087 180 0.042
peptidyl lysine modification GO:0018205 144 0.041
internal protein amino acid acetylation GO:0006475 101 0.040
sister chromatid cohesion GO:0007062 24 0.040
cellular response to reactive oxygen species GO:0034614 50 0.040
ncrna metabolic process GO:0034660 108 0.039
chemotaxis GO:0006935 157 0.039
chromatin remodeling GO:0006338 55 0.038
axonogenesis GO:0007409 31 0.038
metencephalon development GO:0022037 2 0.037
cell junction organization GO:0034330 79 0.037
hindbrain development GO:0030902 3 0.036
positive regulation of cellular catabolic process GO:0031331 284 0.036
embryonic organ development GO:0048568 36 0.035
gtp catabolic process GO:0006184 237 0.035
regulation of synaptic plasticity GO:0048167 3 0.034
multicellular organismal aging GO:0010259 3 0.034
female gamete generation GO:0007292 2 0.034
meiotic chromosome segregation GO:0045132 4 0.034
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.034
regulation of cellular amine metabolic process GO:0033238 11 0.034
somitogenesis GO:0001756 2 0.033
memory GO:0007613 3 0.032
chromosome segregation GO:0007059 114 0.032
cellular response to oxygen containing compound GO:1901701 276 0.031
regulation of cell cycle GO:0051726 393 0.031
axis elongation GO:0003401 4 0.031
purine containing compound catabolic process GO:0072523 411 0.030
regulation of protein stability GO:0031647 87 0.030
Human
histone acetylation GO:0016573 93 0.030
leukocyte differentiation GO:0002521 98 0.030
system process GO:0003008 349 0.029
central nervous system neuron development GO:0021954 7 0.029
behavior GO:0007610 112 0.028
regulation of neuron projection development GO:0010975 57 0.028
cytoplasmic transport GO:0016482 379 0.028
protein acylation GO:0043543 138 0.028
regulation of wnt signaling pathway GO:0030111 123 0.028
nucleotide excision repair GO:0006289 31 0.028
positive regulation of catabolic process GO:0009896 310 0.027
cell part morphogenesis GO:0032990 137 0.027
positive regulation of developmental process GO:0051094 314 0.027
morphogenesis of a polarized epithelium GO:0001738 3 0.027
developmental process involved in reproduction GO:0003006 66 0.026
regulation of cellular ketone metabolic process GO:0010565 50 0.026
response to acid chemical GO:0001101 66 0.026
purine ribonucleoside catabolic process GO:0046130 398 0.026
carbohydrate metabolic process GO:0005975 207 0.026
nucleoside phosphate catabolic process GO:1901292 412 0.026
rna processing GO:0006396 255 0.026
Human
cellular amine metabolic process GO:0044106 41 0.025
amine metabolic process GO:0009308 44 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
protein modification by small protein removal GO:0070646 92 0.024
organophosphate biosynthetic process GO:0090407 163 0.024
nucleoside catabolic process GO:0009164 408 0.024
regulation of intracellular transport GO:0032386 195 0.024
purine nucleoside triphosphate catabolic process GO:0009146 392 0.024
positive regulation of gtp catabolic process GO:0033126 166 0.024
wnt signaling pathway GO:0016055 156 0.024
response to organonitrogen compound GO:0010243 156 0.024
positive regulation of cellular amine metabolic process GO:0033240 7 0.024
neurological system process GO:0050877 163 0.024
cellular ketone metabolic process GO:0042180 80 0.023
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.023
sex differentiation GO:0007548 45 0.023
cell maturation GO:0048469 11 0.023
single organism membrane organization GO:0044802 268 0.023
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.023
Human
cellular response to growth factor stimulus GO:0071363 197 0.022
Human
motor neuron axon guidance GO:0008045 2 0.022
nucleoside triphosphate catabolic process GO:0009143 394 0.022
transcription coupled nucleotide excision repair GO:0006283 8 0.022
negative regulation of cellular amine metabolic process GO:0033239 3 0.022
response to lipid GO:0033993 206 0.022
regulation of axonogenesis GO:0050770 16 0.022
blastocyst development GO:0001824 3 0.022
cellular response to hydrogen peroxide GO:0070301 37 0.022
response to reactive oxygen species GO:0000302 61 0.022
positive regulation of protein ubiquitination GO:0031398 53 0.022
neuron projection guidance GO:0097485 12 0.022
regulation of protein transport GO:0051223 213 0.022
ubiquitin dependent protein catabolic process GO:0006511 206 0.022
Human
embryonic skeletal system morphogenesis GO:0048704 9 0.021
protein localization to nucleus GO:0034504 136 0.021
regulation of cell morphogenesis GO:0022604 153 0.021
establishment of planar polarity GO:0001736 3 0.021
determination of adult lifespan GO:0008340 2 0.021
tripartite regional subdivision GO:0007351 2 0.021
anterior posterior axis specification embryo GO:0008595 2 0.021
maintenance of location GO:0051235 112 0.021
neuron projection regeneration GO:0031102 1 0.020
posttranscriptional regulation of gene expression GO:0010608 213 0.020
Human
nuclear transport GO:0051169 179 0.020
response to retinoic acid GO:0032526 33 0.020
positive regulation of nucleotide catabolic process GO:0030813 185 0.020
epithelial cell proliferation GO:0050673 128 0.020
single organism nuclear import GO:1902593 104 0.020
cellular response to hormone stimulus GO:0032870 125 0.020
response to drug GO:0042493 81 0.020
regulation of growth GO:0040008 165 0.020
axon regeneration GO:0031103 1 0.020
embryonic skeletal system development GO:0048706 13 0.019
glycosyl compound catabolic process GO:1901658 413 0.019
intracellular protein transport GO:0006886 270 0.019
regulation of neuron projection regeneration GO:0070570 1 0.019
ribonucleoprotein complex assembly GO:0022618 78 0.019
Human
positive regulation of protein kinase activity GO:0045860 190 0.019
dna modification GO:0006304 27 0.019
mrna processing GO:0006397 133 0.019
Human
positive regulation of nucleotide metabolic process GO:0045981 230 0.019
nuclear division GO:0000280 128 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.019
Human
gtp metabolic process GO:0046039 239 0.018
negative regulation of wnt signaling pathway GO:0030178 69 0.018
mrna metabolic process GO:0016071 175 0.018
Human
regulation of nucleotide catabolic process GO:0030811 205 0.018
response to alcohol GO:0097305 64 0.018
regulation of nucleoside metabolic process GO:0009118 209 0.018
regulation of purine nucleotide catabolic process GO:0033121 205 0.018
nucleoside triphosphate metabolic process GO:0009141 422 0.018
regulation of dna metabolic process GO:0051052 153 0.018
regulation of protein targeting GO:1903533 91 0.017
axon guidance GO:0007411 12 0.017
regulation of cell development GO:0060284 161 0.017
response to hormone GO:0009725 175 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.017
Human
purine nucleoside catabolic process GO:0006152 398 0.017
response to axon injury GO:0048678 1 0.017
regulation of nervous system development GO:0051960 88 0.017
mating GO:0007618 1 0.017
organophosphate catabolic process GO:0046434 430 0.017
dendritic spine morphogenesis GO:0060997 3 0.017
regulation of chondrocyte differentiation GO:0032330 9 0.017
inner ear morphogenesis GO:0042472 4 0.016
cell cycle phase transition GO:0044770 173 0.016
establishment of protein localization to organelle GO:0072594 172 0.016
positive regulation of hydrolase activity GO:0051345 331 0.016
positive regulation of nucleoside metabolic process GO:0045979 186 0.016
oocyte differentiation GO:0009994 2 0.016
negative regulation of cell cycle GO:0045786 193 0.016
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.016
lipid biosynthetic process GO:0008610 177 0.016
nucleotide catabolic process GO:0009166 408 0.015
response to camp GO:0051591 25 0.015
regulation of mitotic cell cycle GO:0007346 189 0.015
purine ribonucleotide catabolic process GO:0009154 404 0.015
mitotic cell cycle process GO:1903047 286 0.015
regulation of epithelial cell proliferation GO:0050678 113 0.015
stem cell division GO:0017145 2 0.015
ribonucleoside triphosphate metabolic process GO:0009199 412 0.015
dephosphorylation GO:0016311 209 0.015
regulation of t cell differentiation in thymus GO:0033081 2 0.015
signal transduction by p53 class mediator GO:0072331 72 0.015
peptidyl tyrosine modification GO:0018212 170 0.015
central nervous system development GO:0007417 123 0.015
cellular response to organonitrogen compound GO:0071417 124 0.015
cell fate determination GO:0001709 3 0.015
sensory organ morphogenesis GO:0090596 21 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
nuclear import GO:0051170 106 0.014
limbic system development GO:0021761 3 0.014
cell cycle checkpoint GO:0000075 117 0.014
protein import GO:0017038 130 0.014
leukocyte activation GO:0045321 164 0.014
somatic muscle development GO:0007525 1 0.014
positive regulation of response to external stimulus GO:0032103 88 0.014
regulation of gtp catabolic process GO:0033124 180 0.014
regeneration GO:0031099 4 0.014
positive regulation of protein phosphorylation GO:0001934 313 0.014
primary neural tube formation GO:0014020 3 0.014
regulation of protein catabolic process GO:0042176 155 0.014
rab protein signal transduction GO:0032482 4 0.014
ribonucleoprotein complex biogenesis GO:0022613 116 0.014
Human
negative regulation of intracellular signal transduction GO:1902532 183 0.014
ras protein signal transduction GO:0007265 73 0.014
cellular lipid metabolic process GO:0044255 303 0.014
digestive tract development GO:0048565 75 0.014
autophagy GO:0006914 88 0.014
regulation of cell cycle phase transition GO:1901987 126 0.013
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.013
purine nucleoside triphosphate metabolic process GO:0009144 412 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
Human
urogenital system development GO:0001655 65 0.013
mitochondrion organization GO:0007005 156 0.013
lymphocyte activation GO:0046649 133 0.013
cellular response to dna damage stimulus GO:0006974 379 0.013
response to other organism GO:0051707 261 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
regulation of protein localization GO:0032880 296 0.013
regulation of mitotic cell cycle phase transition GO:1901990 118 0.013
cellular macromolecular complex assembly GO:0034622 324 0.013
Human
single organism carbohydrate metabolic process GO:0044723 193 0.013
secretion GO:0046903 254 0.013
oogenesis GO:0048477 2 0.013
cell division GO:0051301 168 0.013
immune response GO:0006955 307 0.013
negative regulation of transport GO:0051051 176 0.013
lipid metabolic process GO:0006629 381 0.013
regulation of cell division GO:0051302 116 0.013
response to uv GO:0009411 73 0.013
regulation of ras gtpase activity GO:0032318 128 0.013
cellular protein catabolic process GO:0044257 261 0.012
Human
organelle fission GO:0048285 149 0.012
negative regulation of cellular component movement GO:0051271 106 0.012
negative regulation of axonogenesis GO:0050771 4 0.012
ventral spinal cord development GO:0021517 1 0.012
protein catabolic process GO:0030163 325 0.012
Human
oocyte development GO:0048599 1 0.012
embryonic hemopoiesis GO:0035162 4 0.012
regulation of intracellular protein transport GO:0033157 123 0.012
modification dependent macromolecule catabolic process GO:0043632 212 0.012
Human
response to light stimulus GO:0009416 87 0.012
protein localization to organelle GO:0033365 280 0.012
sulfur compound metabolic process GO:0006790 101 0.012
negative regulation of translation GO:0017148 37 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
regulation of meiotic cell cycle GO:0051445 4 0.012
embryo development ending in birth or egg hatching GO:0009792 34 0.012
peptidyl tyrosine phosphorylation GO:0018108 170 0.012
protein import into nucleus GO:0006606 104 0.012
syncytium formation by plasma membrane fusion GO:0000768 2 0.012
cell activation GO:0001775 213 0.012
anterior posterior pattern specification GO:0009952 9 0.012
spermatid development GO:0007286 4 0.012
adult locomotory behavior GO:0008344 1 0.012
ribonucleotide catabolic process GO:0009261 405 0.012
ribonucleoside catabolic process GO:0042454 406 0.012
endomembrane system organization GO:0010256 196 0.012
long term memory GO:0007616 2 0.012
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.012
histone deubiquitination GO:0016578 16 0.011
developmental growth GO:0048589 48 0.011
regulation of signal transduction by p53 class mediator GO:1901796 26 0.011
regulation of protein secretion GO:0050708 86 0.011
cellular response to nitrogen compound GO:1901699 144 0.011
short term memory GO:0007614 1 0.011
circadian behavior GO:0048512 2 0.011
morphogenesis of embryonic epithelium GO:0016331 4 0.011
positive regulation of mitotic cell cycle GO:0045931 60 0.011
thymus development GO:0048538 3 0.011
purine nucleotide catabolic process GO:0006195 405 0.011
regulation of neuroblast proliferation GO:1902692 3 0.011
rhythmic behavior GO:0007622 2 0.011
rna modification GO:0009451 27 0.011
cellular response to endogenous stimulus GO:0071495 336 0.011
Human
neural tube closure GO:0001843 3 0.011
membrane organization GO:0061024 292 0.011
monovalent inorganic cation transport GO:0015672 128 0.011
growth hormone secretion GO:0030252 4 0.011
dna methylation or demethylation GO:0044728 19 0.011
dendritic spine organization GO:0097061 4 0.011
appendage development GO:0048736 23 0.011
translation GO:0006412 132 0.011
rna 5 end processing GO:0000966 2 0.011
response to ketone GO:1901654 19 0.011
regulation of multi organism process GO:0043900 157 0.011
pathway restricted smad protein phosphorylation GO:0060389 38 0.010
Human
positive regulation of gtpase activity GO:0043547 166 0.010
cell junction assembly GO:0034329 67 0.010
cytokinesis GO:0000910 96 0.010
response to biotic stimulus GO:0009607 276 0.010
tube closure GO:0060606 3 0.010
embryonic epithelial tube formation GO:0001838 4 0.010
regulation of cell growth GO:0001558 135 0.010
regulation of nucleotide metabolic process GO:0006140 269 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.010
growth GO:0040007 202 0.010
negative regulation of cellular component organization GO:0051129 235 0.010
cell growth GO:0016049 160 0.010
regulation of cell differentiation GO:0045595 393 0.010
positive regulation of cell differentiation GO:0045597 211 0.010
intracellular mrna localization GO:0008298 1 0.010

USP11 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of mental health DOID:150 70 0.015
central nervous system disease DOID:331 186 0.015
nervous system disease DOID:863 431 0.015
brain disease DOID:936 73 0.012
neonatal period electroclinical syndrome DOID:0050702 19 0.011
epilepsy syndrome DOID:1826 41 0.011
electroclinical syndrome DOID:0050701 32 0.011
eye and adnexa disease DOID:1492 150 0.011
sensory system disease DOID:0050155 203 0.011
eye disease DOID:5614 149 0.011
retinal disease DOID:5679 118 0.011
retinal degeneration DOID:8466 89 0.011