Homo sapiens

34 known processes

USP8

ubiquitin specific peptidase 8

(Aliases: HumORF8,MGC129718,FLJ34456,UBPY,KIAA0055)

USP8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
endomembrane system organization GO:0010256 196 0.671
viral budding GO:0046755 9 0.653
regulation of cell cycle GO:0051726 393 0.532
Human
cell division GO:0051301 168 0.449
ras protein signal transduction GO:0007265 73 0.418
Mouse
cytokinesis GO:0000910 96 0.391
cellular macromolecule catabolic process GO:0044265 380 0.356
Yeast
vesicle mediated transport GO:0016192 371 0.355
Yeast
cytoplasmic transport GO:0016482 379 0.343
membrane organization GO:0061024 292 0.253
Yeast
viral budding via host escrt complex GO:0039702 7 0.222
regulation of vesicle mediated transport GO:0060627 130 0.199
membrane budding GO:0006900 28 0.194
Yeast
nucleoside monophosphate catabolic process GO:0009125 159 0.177
cellular response to starvation GO:0009267 58 0.152
macroautophagy GO:0016236 39 0.146
positive regulation of exosomal secretion GO:1903543 12 0.139
positive regulation of transport GO:0051050 336 0.138
protein localization to plasma membrane GO:0072659 93 0.137
positive regulation of cell proliferation GO:0008284 301 0.136
vesicle organization GO:0016050 62 0.130
Yeast
protein catabolic process GO:0030163 325 0.127
Yeast
virion assembly GO:0019068 14 0.126
cellular macromolecular complex assembly GO:0034622 324 0.115
cell cycle phase transition GO:0044770 173 0.115
intracellular protein transport GO:0006886 270 0.112
multi organism membrane organization GO:0044803 12 0.107
maintenance of location in cell GO:0051651 62 0.103
cellular protein catabolic process GO:0044257 261 0.103
Yeast
atp metabolic process GO:0046034 176 0.095
regulation of cytokinesis GO:0032465 45 0.093
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.090
purine ribonucleotide catabolic process GO:0009154 404 0.089
regulation of cell cycle process GO:0010564 266 0.087
viral life cycle GO:0019058 132 0.086
endosomal transport GO:0016197 129 0.085
purine nucleoside triphosphate metabolic process GO:0009144 412 0.083
nucleoside catabolic process GO:0009164 408 0.082
plasma membrane organization GO:0007009 115 0.078
autophagy GO:0006914 88 0.075
long term memory GO:0007616 2 0.075
mitotic cell cycle GO:0000278 326 0.074
single organism membrane organization GO:0044802 268 0.072
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.071
Yeast
nucleoside phosphate catabolic process GO:1901292 412 0.071
cellular amino acid metabolic process GO:0006520 116 0.070
nucleoside triphosphate metabolic process GO:0009141 422 0.070
atp catabolic process GO:0006200 157 0.069
multi organism membrane budding GO:1902592 9 0.067
glycerophospholipid metabolic process GO:0006650 84 0.066
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.065
organophosphate catabolic process GO:0046434 430 0.064
regulation of small gtpase mediated signal transduction GO:0051056 156 0.064
mitotic cell cycle phase transition GO:0044772 162 0.063
protein localization to membrane GO:0072657 160 0.063
interspecies interaction between organisms GO:0044419 156 0.060
multi organism cellular process GO:0044764 156 0.058
positive regulation of ras gtpase activity GO:0032320 117 0.057
lipid metabolic process GO:0006629 381 0.057
microtubule cytoskeleton organization GO:0000226 176 0.055
protein oligomerization GO:0051259 173 0.054
locomotory behavior GO:0007626 1 0.054
ribonucleoside triphosphate metabolic process GO:0009199 412 0.054
multi organism organelle organization GO:1902590 9 0.052
regulation of establishment of protein localization to plasma membrane GO:0090003 30 0.051
regulation of mitotic cell cycle GO:0007346 189 0.050
Human
nucleotide catabolic process GO:0009166 408 0.050
regulation of cell division GO:0051302 116 0.050
maintenance of location GO:0051235 112 0.049
purine nucleoside triphosphate catabolic process GO:0009146 392 0.049
ribonucleotide catabolic process GO:0009261 405 0.048
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.047
microtubule based process GO:0007017 210 0.047
response to starvation GO:0042594 59 0.047
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.045
cell cycle g2 m phase transition GO:0044839 43 0.044
purine containing compound catabolic process GO:0072523 411 0.043
positive regulation of viral release from host cell GO:1902188 5 0.041
viral release from host cell GO:0019076 21 0.041
glycosyl compound catabolic process GO:1901658 413 0.039
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.039
purine nucleoside monophosphate catabolic process GO:0009128 158 0.038
positive regulation of multi organism process GO:0043902 56 0.037
negative regulation of cellular catabolic process GO:0031330 83 0.037
purine nucleoside monophosphate metabolic process GO:0009126 186 0.036
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.036
nucleoside monophosphate metabolic process GO:0009123 191 0.034
cellular response to nutrient levels GO:0031669 69 0.034
purine nucleoside catabolic process GO:0006152 398 0.034
regulation of viral process GO:0050792 103 0.034
small gtpase mediated signal transduction GO:0007264 78 0.033
Mouse
response to growth factor GO:0070848 205 0.033
regulation of protein catabolic process GO:0042176 155 0.033
ribonucleoside monophosphate metabolic process GO:0009161 187 0.032
establishment of protein localization to membrane GO:0090150 121 0.032
segmentation GO:0035282 4 0.032
lipid modification GO:0030258 84 0.031
maintenance of protein location GO:0045185 57 0.031
abscission GO:0009838 5 0.031
neuromuscular junction development GO:0007528 3 0.031
purine ribonucleoside catabolic process GO:0046130 398 0.030
carbohydrate metabolic process GO:0005975 207 0.030
negative regulation of phosphorylation GO:0042326 174 0.030
negative regulation of catabolic process GO:0009895 104 0.030
leukocyte activation GO:0045321 164 0.030
ribonucleoside catabolic process GO:0042454 406 0.030
negative regulation of cellular protein metabolic process GO:0032269 353 0.029
oogenesis GO:0048477 2 0.029
ribonucleoside monophosphate catabolic process GO:0009158 158 0.029
establishment of protein localization to plasma membrane GO:0090002 68 0.029
enzyme linked receptor protein signaling pathway GO:0007167 303 0.029
neural tube formation GO:0001841 3 0.028
negative regulation of protein metabolic process GO:0051248 391 0.028
positive regulation of cellular amine metabolic process GO:0033240 7 0.028
response to oxygen levels GO:0070482 100 0.028
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.028
cellular response to endogenous stimulus GO:0071495 336 0.027
protein localization to endoplasmic reticulum GO:0070972 19 0.027
establishment of protein localization to organelle GO:0072594 172 0.027
regulation of cellular component biogenesis GO:0044087 281 0.027
blastoderm segmentation GO:0007350 2 0.026
mitochondrion organization GO:0007005 156 0.026
regulation of mitotic cell cycle phase transition GO:1901990 118 0.026
regulation of proteolysis GO:0030162 293 0.026
regulation of locomotion GO:0040012 329 0.026
determination of adult lifespan GO:0008340 2 0.025
cellular amine metabolic process GO:0044106 41 0.025
mitotic cell cycle checkpoint GO:0007093 68 0.024
cellular response to external stimulus GO:0071496 111 0.024
gtp catabolic process GO:0006184 237 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.024
lipid transport GO:0006869 90 0.024
negative regulation of cytokinesis GO:0032466 3 0.024
purine nucleotide catabolic process GO:0006195 405 0.023
embryo development GO:0009790 123 0.023
cellular response to extracellular stimulus GO:0031668 72 0.023
apoptotic signaling pathway GO:0097190 268 0.022
mapk cascade GO:0000165 288 0.022
single organism cellular localization GO:1902580 332 0.021
Yeast
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.021
growth GO:0040007 202 0.021
viral process GO:0016032 146 0.020
negative regulation of cell cycle phase transition GO:1901988 89 0.020
establishment or maintenance of cell polarity GO:0007163 31 0.020
regulation of cell cycle phase transition GO:1901987 126 0.020
ribonucleoside triphosphate catabolic process GO:0009203 391 0.020
negative regulation of growth GO:0045926 97 0.020
regulation of purine nucleotide metabolic process GO:1900542 264 0.019
negative regulation of epithelial cell proliferation GO:0050680 48 0.019
protein targeting GO:0006605 187 0.019
protein ubiquitination GO:0016567 314 0.019
nervous system development GO:0007399 293 0.019
regulation of ras gtpase activity GO:0032318 128 0.018
glycerolipid metabolic process GO:0046486 107 0.018
cytoskeleton dependent intracellular transport GO:0030705 21 0.018
phosphatidylinositol metabolic process GO:0046488 53 0.018
microtubule organizing center organization GO:0031023 62 0.018
cellular response to oxygen levels GO:0071453 55 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.018
response to extracellular stimulus GO:0009991 85 0.017
response to decreased oxygen levels GO:0036293 96 0.017
single organism nuclear import GO:1902593 104 0.017
positive regulation of gtp catabolic process GO:0033126 166 0.017
positive regulation of cytokinesis GO:0032467 29 0.017
regulation of cellular ketone metabolic process GO:0010565 50 0.016
axon cargo transport GO:0008088 2 0.016
positive regulation of immune system process GO:0002684 283 0.016
negative regulation of secretion by cell GO:1903531 52 0.016
amine metabolic process GO:0009308 44 0.016
signal transduction by phosphorylation GO:0023014 297 0.016
positive regulation of viral process GO:0048524 37 0.016
protein localization to organelle GO:0033365 280 0.016
negative regulation of kinase activity GO:0033673 106 0.016
regulation of g2 m transition of mitotic cell cycle GO:0010389 20 0.015
maintenance of cell polarity GO:0030011 2 0.015
epithelial cell proliferation GO:0050673 128 0.015
nuclear transport GO:0051169 179 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
erbb signaling pathway GO:0038127 44 0.015
negative regulation of cell cycle process GO:0010948 121 0.015
positive regulation of gtpase activity GO:0043547 166 0.015
regulation of multi organism process GO:0043900 157 0.014
generation of neurons GO:0048699 152 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.014
regulation of cell differentiation GO:0045595 393 0.014
chemotaxis GO:0006935 157 0.014
positive regulation of cell cycle GO:0045787 140 0.014
Human
establishment of cell polarity GO:0030010 22 0.014
regulation of mapk cascade GO:0043408 262 0.014
vacuole organization GO:0007033 44 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
cell morphogenesis involved in differentiation GO:0000904 144 0.014
anterior posterior axis specification GO:0009948 2 0.014
regulation of ras protein signal transduction GO:0046578 155 0.014
single organism membrane fusion GO:0044801 37 0.014
female gamete generation GO:0007292 2 0.014
post embryonic development GO:0009791 2 0.013
Fly
regulation of cellular amino acid metabolic process GO:0006521 6 0.013
regulation of nucleoside metabolic process GO:0009118 209 0.013
regulation of erbb signaling pathway GO:1901184 27 0.013
biological adhesion GO:0022610 331 0.013
neurogenesis GO:0022008 169 0.013
regulation of nucleotide metabolic process GO:0006140 269 0.012
negative regulation of cell cycle GO:0045786 193 0.012
regulation of cellular protein catabolic process GO:1903362 96 0.012
potassium ion transport GO:0006813 62 0.012
protein modification by small protein conjugation GO:0032446 342 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
phospholipid biosynthetic process GO:0008654 44 0.012
secretion GO:0046903 254 0.012
protein processing GO:0016485 226 0.011
response to nutrient levels GO:0031667 81 0.011
system process GO:0003008 349 0.011
exocytosis GO:0006887 71 0.011
single organism reproductive process GO:0044702 98 0.011
positive regulation of protein transport GO:0051222 135 0.011
rna processing GO:0006396 255 0.011
covalent chromatin modification GO:0016569 254 0.011
regulation of gtpase activity GO:0043087 180 0.011
central nervous system neuron axonogenesis GO:0021955 3 0.011
positive regulation of cellular component organization GO:0051130 376 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
late endosome to vacuole transport GO:0045324 2 0.011
cellular ketone metabolic process GO:0042180 80 0.010
multicellular organism reproduction GO:0032504 42 0.010
protein localization to nucleus GO:0034504 136 0.010
mrna metabolic process GO:0016071 175 0.010
maintenance of protein location in cell GO:0032507 56 0.010
regulation of nucleotide catabolic process GO:0030811 205 0.010
post golgi vesicle mediated transport GO:0006892 36 0.010
behavior GO:0007610 112 0.010
cell cycle checkpoint GO:0000075 117 0.010
response to peptide hormone GO:0043434 61 0.010
positive regulation of nucleoside metabolic process GO:0045979 186 0.010

USP8 disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.036
disease of cellular proliferation DOID:14566 174 0.036
organ system cancer DOID:0050686 164 0.036
central nervous system disease DOID:331 186 0.022
nervous system disease DOID:863 431 0.022