|
|
protein catabolic process
|
GO:0030163 |
325 |
0.834
|
Fly |
|
|
neural tube formation
|
GO:0001841 |
3 |
0.831
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.810
|
Fly |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.778
|
Human |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.697
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.672
|
Fly |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.658
|
Fly |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.564
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.532
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.518
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.502
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.481
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.480
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.476
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.458
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.442
|
Fly |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.422
|
Fly |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.412
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.403
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.386
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.381
|
Human |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.379
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.369
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.344
|
|
|
|
tube closure
|
GO:0060606 |
3 |
0.337
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.324
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.320
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.308
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.308
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.303
|
Human |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.300
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.300
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.298
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.295
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.283
|
Human |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.283
|
Human |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.282
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.281
|
Fly |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.280
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.279
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.276
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.268
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.263
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.262
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.261
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.260
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.257
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.257
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.253
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.250
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.242
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.239
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.233
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.230
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.228
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.226
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.223
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.222
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.220
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.219
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.218
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.213
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.212
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.211
|
|
|
|
system process
|
GO:0003008 |
349 |
0.209
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.208
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.205
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.204
|
Fly |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.202
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.198
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.198
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.196
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.195
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.191
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.188
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.185
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.183
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.181
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.177
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.174
|
Fly |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.174
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.173
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.172
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.167
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.165
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.165
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.164
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.164
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.159
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.154
|
|
|
|
growth
|
GO:0040007 |
202 |
0.154
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.152
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.151
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.150
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.150
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.149
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.149
|
Mouse Fly |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.145
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.145
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.144
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.144
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.142
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.141
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.140
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.139
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.135
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.134
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.134
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.134
|
Mouse |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.131
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.130
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.129
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.129
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.127
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.126
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.125
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.123
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.122
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.122
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.121
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.120
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.119
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.119
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.119
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.119
|
Human |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.119
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.118
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.118
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.113
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.113
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.112
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.111
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.111
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.111
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.109
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.109
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.109
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.107
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.107
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.106
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.104
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.104
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.103
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.103
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.103
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.102
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.102
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.102
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.099
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.098
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.098
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.096
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.096
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.095
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.095
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.095
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.094
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.094
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.094
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.091
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.089
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.089
|
Fly |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.089
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.088
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.087
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.087
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.086
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.085
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.083
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.083
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.082
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.081
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.081
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.080
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.080
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.079
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.078
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.077
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.077
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.077
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.076
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.076
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.075
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.075
|
|
|
|
aging
|
GO:0007568 |
66 |
0.075
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.074
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.074
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.073
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.073
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.073
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.072
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.072
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.072
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.071
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.071
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.071
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.071
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.070
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.070
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.070
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.069
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.069
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.068
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.068
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.067
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.066
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.066
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.066
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.066
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.065
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.064
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.064
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.064
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.063
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.063
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.062
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.062
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.062
|
|
|
|
neural tube development
|
GO:0021915 |
9 |
0.062
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.062
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.061
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.061
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.061
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.060
|
Fly |
|
|
histone h3 k27 demethylation
|
GO:0071557 |
3 |
0.060
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.060
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.060
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.059
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.059
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.058
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.058
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.058
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.058
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.057
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.056
|
Fly |
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.056
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.056
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.056
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.055
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.055
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.055
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.054
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.054
|
Fly |
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.054
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.054
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.053
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.053
|
|
|
|
head development
|
GO:0060322 |
108 |
0.053
|
Mouse |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.053
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.053
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.052
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.052
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.052
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.052
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.052
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.051
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.051
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.051
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.051
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.051
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.051
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.050
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.050
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.049
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.049
|
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
1 |
0.049
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.049
|
Mouse |
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.048
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.048
|
|
|
|
vesicle targeting rough er to cis golgi
|
GO:0048207 |
2 |
0.048
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.047
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.047
|
Fly |
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.047
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.047
|
Mouse |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.045
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.045
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.045
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.045
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.045
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.044
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.044
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.044
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.043
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.043
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.042
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.042
|
|
|
|
respiratory gaseous exchange
|
GO:0007585 |
3 |
0.042
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.042
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.041
|
|
|
|
golgi vesicle transport
|
GO:0048193 |
80 |
0.041
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.041
|
|
|
|
copii vesicle coating
|
GO:0048208 |
2 |
0.041
|
|
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.041
|
Fly |
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.041
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.041
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.040
|
|
|
|
demethylation
|
GO:0070988 |
37 |
0.040
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.040
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.040
|
Mouse |
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.039
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.039
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.039
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.039
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.038
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.038
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.038
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.038
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.037
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.037
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.037
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.036
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.036
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.036
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.036
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.036
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.035
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.035
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.035
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.035
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.035
|
Fly |
|
|
endocytosis
|
GO:0006897 |
159 |
0.035
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.035
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.035
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.034
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.034
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.034
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.034
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.034
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.033
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.033
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.033
|
Mouse |
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.033
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.032
|
Fly |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.032
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.032
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.032
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.032
|
Fly |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.032
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.032
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.031
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.031
|
|
|
|
protein methylation
|
GO:0006479 |
74 |
0.031
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.031
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.031
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.031
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.031
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.031
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.031
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.031
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.030
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.030
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.030
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.030
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.030
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.030
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.030
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.030
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.029
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.029
|
|
|
|
mitotic sister chromatid separation
|
GO:0051306 |
18 |
0.029
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.028
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.028
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.028
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.028
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.028
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.028
|
Fly |
|
|
trophectodermal cell differentiation
|
GO:0001829 |
3 |
0.028
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.028
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.028
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.028
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.028
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.027
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.027
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.027
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.027
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.027
|
|
|
|
protein dealkylation
|
GO:0008214 |
17 |
0.027
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.027
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.027
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.027
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.027
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.027
|
|
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.027
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.027
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.027
|
Mouse |
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.027
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.027
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.027
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.027
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.026
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.026
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.026
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.026
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.025
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.025
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.025
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.025
|
|
|
|
negative regulation of viral process
|
GO:0048525 |
66 |
0.025
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.025
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.025
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.025
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.025
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
40 |
0.025
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.025
|
Fly |
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.025
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.025
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.025
|
Fly |
|
|
immune response
|
GO:0006955 |
307 |
0.025
|
Fly |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.025
|
|
|
|
positive regulation of response to dna damage stimulus
|
GO:2001022 |
43 |
0.025
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.024
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.024
|
|
|
|
histone demethylation
|
GO:0016577 |
15 |
0.024
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.024
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.024
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.024
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.024
|
|
|
|
blastocyst formation
|
GO:0001825 |
3 |
0.024
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.024
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.024
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.024
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.023
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.023
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
8 |
0.023
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.023
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.023
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.023
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.023
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.023
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.023
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.023
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.023
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.023
|
|
|
|
nuclear migration
|
GO:0007097 |
1 |
0.022
|
Fly |
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.022
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.022
|
Fly |
|
|
protein demethylation
|
GO:0006482 |
17 |
0.022
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.022
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.022
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.022
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.022
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.022
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.022
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.022
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.022
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.022
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.021
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.021
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.021
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.021
|
|
|
|
metaphase anaphase transition of cell cycle
|
GO:0044784 |
21 |
0.021
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.021
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.021
|
|
|
|
regulation of sister chromatid segregation
|
GO:0033045 |
27 |
0.021
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.021
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.021
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.021
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.021
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.021
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.021
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.021
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.021
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.021
|
Fly |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.021
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.020
|
|
|
|
regulation of rab protein signal transduction
|
GO:0032483 |
39 |
0.020
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.020
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.020
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.020
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.020
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.020
|
|
|
|
regulation of rab gtpase activity
|
GO:0032313 |
39 |
0.020
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.020
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.020
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.019
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.019
|
Fly |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.019
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.019
|
Mouse |
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.019
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.019
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.019
|
Fly |
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.019
|
|
|
|
tube formation
|
GO:0035148 |
10 |
0.019
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.019
|
Fly |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.019
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.019
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.019
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.018
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.018
|
|
