Homo sapiens

95 known processes

VAMP8

vesicle-associated membrane protein 8 (endobrevin)

(Aliases: EDB,VAMP-8)

VAMP8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
membrane organization GO:0061024 292 0.414
single organism membrane fusion GO:0044801 37 0.383
vesicle fusion GO:0006906 17 0.350
Mouse
vesicle organization GO:0016050 62 0.339
Mouse
vesicle mediated transport GO:0016192 371 0.328
Mouse
protein localization to membrane GO:0072657 160 0.292
organelle fusion GO:0048284 36 0.266
regulation of protein localization to plasma membrane GO:1903076 40 0.245
endomembrane system organization GO:0010256 196 0.244
endosome to lysosome transport GO:0008333 21 0.225
single organism membrane organization GO:0044802 268 0.199
oxidation reduction process GO:0055114 396 0.193
membrane fusion GO:0061025 43 0.153
snare complex assembly GO:0035493 3 0.144
Mouse
regulation of protein localization GO:0032880 296 0.133
endosomal transport GO:0016197 129 0.120
cellular protein complex assembly GO:0043623 188 0.105
Mouse
cellular chemical homeostasis GO:0055082 180 0.094
plasma membrane organization GO:0007009 115 0.091
protein localization to plasma membrane GO:0072659 93 0.090
cellular amino acid metabolic process GO:0006520 116 0.090
post embryonic development GO:0009791 2 0.087
multicellular organismal aging GO:0010259 3 0.086
cellular lipid metabolic process GO:0044255 303 0.081
response to oxygen containing compound GO:1901700 369 0.079
positive regulation of cell motility GO:2000147 177 0.078
single organism cellular localization GO:1902580 332 0.078
positive regulation of transport GO:0051050 336 0.072
determination of adult lifespan GO:0008340 2 0.066
vacuole organization GO:0007033 44 0.063
regulation of apoptotic signaling pathway GO:2001233 175 0.062
secretion GO:0046903 254 0.060
regulation of vesicle mediated transport GO:0060627 130 0.060
Mouse
cellular response to oxygen containing compound GO:1901701 276 0.058
lipid localization GO:0010876 106 0.057
cytoplasmic transport GO:0016482 379 0.056
lysosomal transport GO:0007041 33 0.056
regulation of synaptic plasticity GO:0048167 3 0.054
response to lipid GO:0033993 206 0.054
monocarboxylic acid metabolic process GO:0032787 185 0.054
organic hydroxy compound transport GO:0015850 63 0.054
positive regulation of synaptic transmission GO:0050806 4 0.053
cellular macromolecular complex assembly GO:0034622 324 0.053
Mouse
regulation of peptidase activity GO:0052547 180 0.052
cell adhesion GO:0007155 325 0.052
long term synaptic potentiation GO:0060291 1 0.051
cellular homeostasis GO:0019725 196 0.051
positive regulation of locomotion GO:0040017 186 0.047
vesicle docking involved in exocytosis GO:0006904 3 0.046
lipid metabolic process GO:0006629 381 0.045
glutathione metabolic process GO:0006749 20 0.041
nervous system development GO:0007399 293 0.040
intracellular protein transport GO:0006886 270 0.040
regulation of cellular component movement GO:0051270 334 0.039
golgi to vacuole transport GO:0006896 3 0.039
positive regulation of cellular component movement GO:0051272 181 0.039
establishment of protein localization to membrane GO:0090150 121 0.039
chemical homeostasis GO:0048878 306 0.038
cellular response to endogenous stimulus GO:0071495 336 0.038
regulation of establishment of protein localization GO:0070201 242 0.038
cellular component morphogenesis GO:0032989 314 0.037
lipid transport GO:0006869 90 0.037
positive regulation of cell migration GO:0030335 172 0.036
negative regulation of cell death GO:0060548 345 0.036
nucleoside triphosphate metabolic process GO:0009141 422 0.036
fatty acid metabolic process GO:0006631 115 0.036
carbohydrate metabolic process GO:0005975 207 0.036
negative regulation of cellular protein metabolic process GO:0032269 353 0.036
regulation of cell motility GO:2000145 299 0.036
autophagy GO:0006914 88 0.035
amine metabolic process GO:0009308 44 0.035
golgi vesicle transport GO:0048193 80 0.034
regulation of proteolysis GO:0030162 293 0.034
cell morphogenesis GO:0000902 296 0.034
negative regulation of protein metabolic process GO:0051248 391 0.034
sulfur compound metabolic process GO:0006790 101 0.034
immune response GO:0006955 307 0.034
cellular amide metabolic process GO:0043603 69 0.033
purine containing compound catabolic process GO:0072523 411 0.033
apoptotic signaling pathway GO:0097190 268 0.033
regulation of cell migration GO:0030334 289 0.033
biological adhesion GO:0022610 331 0.033
negative regulation of programmed cell death GO:0043069 321 0.033
nucleoside phosphate catabolic process GO:1901292 412 0.032
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.032
regulation of locomotion GO:0040012 329 0.032
cellular amine metabolic process GO:0044106 41 0.031
negative regulation of catalytic activity GO:0043086 335 0.031
adaptive immune response GO:0002250 49 0.031
epithelium development GO:0060429 227 0.030
secretion by cell GO:0032940 226 0.030
sterol transport GO:0015918 39 0.030
synaptic vesicle exocytosis GO:0016079 3 0.029
locomotory behavior GO:0007626 1 0.029
carboxylic acid biosynthetic process GO:0046394 97 0.029
positive regulation of hydrolase activity GO:0051345 331 0.029
inorganic ion transmembrane transport GO:0098660 231 0.029
positive regulation of immune system process GO:0002684 283 0.028
regulation of cell adhesion GO:0030155 166 0.028
female gamete generation GO:0007292 2 0.028
ribonucleoside catabolic process GO:0042454 406 0.028
posttranscriptional regulation of gene expression GO:0010608 213 0.028
regulation of body fluid levels GO:0050878 99 0.027
taxis GO:0042330 157 0.027
extrinsic apoptotic signaling pathway GO:0097191 119 0.027
small gtpase mediated signal transduction GO:0007264 78 0.026
protein maturation GO:0051604 233 0.026
nitrogen compound transport GO:0071705 191 0.026
cholesterol transport GO:0030301 39 0.026
positive regulation of cellular amine metabolic process GO:0033240 7 0.026
oogenesis GO:0048477 2 0.026
cellular protein catabolic process GO:0044257 261 0.026
regulation of cellular amino acid metabolic process GO:0006521 6 0.025
cellular macromolecule catabolic process GO:0044265 380 0.025
protein processing GO:0016485 226 0.025
small molecule biosynthetic process GO:0044283 157 0.025
regulation of exocytosis GO:0017157 46 0.025
positive regulation of cellular component organization GO:0051130 376 0.025
regeneration GO:0031099 4 0.025
viral process GO:0016032 146 0.025
immune effector process GO:0002252 159 0.024
vacuolar transport GO:0007034 34 0.024
transmembrane transport GO:0055085 399 0.024
maintenance of location GO:0051235 112 0.024
organic acid biosynthetic process GO:0016053 97 0.024
ras protein signal transduction GO:0007265 73 0.024
purine ribonucleoside catabolic process GO:0046130 398 0.024
purine ribonucleoside metabolic process GO:0046128 437 0.024
negative regulation of phosphorus metabolic process GO:0010563 267 0.023
ribonucleoside triphosphate catabolic process GO:0009203 391 0.023
regulation of response to external stimulus GO:0032101 222 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.023
wound healing GO:0042060 115 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.023
purine nucleoside triphosphate catabolic process GO:0009146 392 0.022
organelle inheritance GO:0048308 2 0.022
positive regulation of secretion by cell GO:1903532 108 0.022
positive regulation of secretion GO:0051047 116 0.022
regulation of homeostatic process GO:0032844 121 0.022
organophosphate catabolic process GO:0046434 430 0.022
guanosine containing compound catabolic process GO:1901069 239 0.022
regulation of nucleotide metabolic process GO:0006140 269 0.022
regulation of cellular amine metabolic process GO:0033238 11 0.022
ribonucleoside triphosphate metabolic process GO:0009199 412 0.022
organelle assembly GO:0070925 176 0.022
response to inorganic substance GO:0010035 127 0.021
single organism cell adhesion GO:0098602 179 0.021
single organism carbohydrate metabolic process GO:0044723 193 0.021
regulation of transferase activity GO:0051338 355 0.021
leukocyte mediated immunity GO:0002443 59 0.021
regulation of immune response GO:0050776 201 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
cellular modified amino acid metabolic process GO:0006575 64 0.021
regulation of secretion GO:0051046 194 0.021
negative regulation of apoptotic process GO:0043066 316 0.020
viral life cycle GO:0019058 132 0.020
organelle localization GO:0051640 84 0.020
negative regulation of cellular component organization GO:0051129 235 0.020
response to other organism GO:0051707 261 0.020
regulation of purine nucleotide metabolic process GO:1900542 264 0.020
chemotaxis GO:0006935 157 0.020
response to biotic stimulus GO:0009607 276 0.020
regulation of cellular component biogenesis GO:0044087 281 0.019
spermatid differentiation GO:0048515 4 0.019
glycosyl compound catabolic process GO:1901658 413 0.019
monocarboxylic acid biosynthetic process GO:0072330 67 0.019
organic hydroxy compound metabolic process GO:1901615 147 0.019
defense response GO:0006952 315 0.019
signal transduction by phosphorylation GO:0023014 297 0.019
actin filament based process GO:0030029 224 0.019
segmentation GO:0035282 4 0.019
response to nitrogen compound GO:1901698 184 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.019
positive regulation of proteolysis GO:0045862 142 0.019
regulation of anatomical structure morphogenesis GO:0022603 286 0.019
negative regulation of hydrolase activity GO:0051346 182 0.019
blood coagulation GO:0007596 76 0.018
peptide metabolic process GO:0006518 51 0.018
response to wounding GO:0009611 168 0.018
cellular response to dna damage stimulus GO:0006974 379 0.018
positive regulation of nucleoside metabolic process GO:0045979 186 0.018
regulation of multi organism process GO:0043900 157 0.018
response to hormone GO:0009725 175 0.018
response to organic cyclic compound GO:0014070 204 0.018
protein localization to organelle GO:0033365 280 0.018
anatomical structure formation involved in morphogenesis GO:0048646 284 0.018
cholesterol efflux GO:0033344 28 0.018
cell growth GO:0016049 160 0.018
ameboidal type cell migration GO:0001667 135 0.018
response to organonitrogen compound GO:0010243 156 0.018
neurotransmitter secretion GO:0007269 4 0.018
cellular ketone metabolic process GO:0042180 80 0.018
negative regulation of phosphate metabolic process GO:0045936 267 0.018
cellular response to cytokine stimulus GO:0071345 181 0.017
purine nucleoside triphosphate metabolic process GO:0009144 412 0.017
retrograde transport endosome to golgi GO:0042147 45 0.017
cell projection organization GO:0030030 252 0.017
mapk cascade GO:0000165 288 0.017
regulation of secretion by cell GO:1903530 177 0.017
organonitrogen compound biosynthetic process GO:1901566 200 0.017
reactive oxygen species metabolic process GO:0072593 75 0.017
enzyme linked receptor protein signaling pathway GO:0007167 303 0.017
protein localization to synapse GO:0035418 2 0.017
regulation of intracellular transport GO:0032386 195 0.016
regulation of hormone levels GO:0010817 125 0.016
regulation of response to wounding GO:1903034 101 0.016
modification dependent protein catabolic process GO:0019941 209 0.016
purine nucleoside catabolic process GO:0006152 398 0.016
peptide transport GO:0015833 74 0.016
neuromuscular junction development GO:0007528 3 0.016
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 29 0.016
regulation of cysteine type endopeptidase activity GO:2000116 127 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
negative regulation of transport GO:0051051 176 0.016
cation transport GO:0006812 331 0.016
protein targeting GO:0006605 187 0.016
regulation of immune effector process GO:0002697 91 0.016
activation of cysteine type endopeptidase activity GO:0097202 57 0.016
neurogenesis GO:0022008 169 0.016
positive regulation of endopeptidase activity GO:0010950 84 0.016
epithelial cell migration GO:0010631 119 0.016
epithelium migration GO:0090132 119 0.016
skin development GO:0043588 76 0.015
positive regulation of immune response GO:0050778 159 0.015
regulation of gtpase activity GO:0043087 180 0.015
protein catabolic process GO:0030163 325 0.015
hemostasis GO:0007599 76 0.015
regulation of adaptive immune response GO:0002819 33 0.015
actin cytoskeleton organization GO:0030036 207 0.015
mitochondrion organization GO:0007005 156 0.015
gtp metabolic process GO:0046039 239 0.015
early endosome to late endosome transport GO:0045022 21 0.015
establishment of protein localization to plasma membrane GO:0090002 68 0.015
ion transmembrane transport GO:0034220 338 0.015
adult locomotory behavior GO:0008344 1 0.015
amide transport GO:0042886 76 0.015
lymphocyte mediated immunity GO:0002449 48 0.015
regulation of ion transport GO:0043269 189 0.015
negative regulation of multicellular organismal process GO:0051241 317 0.015
negative regulation of protein modification process GO:0031400 200 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.015
ribonucleotide catabolic process GO:0009261 405 0.015
interspecies interaction between organisms GO:0044419 156 0.015
peripheral nervous system development GO:0007422 2 0.015
regulation of endopeptidase activity GO:0052548 170 0.015
organic acid catabolic process GO:0016054 71 0.015
rho protein signal transduction GO:0007266 26 0.014
metal ion homeostasis GO:0055065 169 0.014
regulation of cellular response to stress GO:0080135 244 0.014
morphogenesis of embryonic epithelium GO:0016331 4 0.014
unsaturated fatty acid metabolic process GO:0033559 37 0.014
regulation of cell differentiation GO:0045595 393 0.014
regulation of lymphocyte mediated immunity GO:0002706 33 0.014
multi organism cellular process GO:0044764 156 0.014
nucleoside catabolic process GO:0009164 408 0.014
response to abiotic stimulus GO:0009628 336 0.014
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.014
cation homeostasis GO:0055080 189 0.014
regulation of protein stability GO:0031647 87 0.014
dephosphorylation GO:0016311 209 0.014
regulation of peptide secretion GO:0002791 42 0.014
fatty acid biosynthetic process GO:0006633 46 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.014
cell killing GO:0001906 34 0.013
regulation of cell growth GO:0001558 135 0.013
purine ribonucleotide catabolic process GO:0009154 404 0.013
regulation of nucleotide catabolic process GO:0030811 205 0.013
nucleotide catabolic process GO:0009166 408 0.013
carbohydrate derivative biosynthetic process GO:1901137 207 0.013
protein polymerization GO:0051258 71 0.013
spermatid development GO:0007286 4 0.013
regulation of protein catabolic process GO:0042176 155 0.013
positive regulation of catabolic process GO:0009896 310 0.013
protein modification by small protein conjugation GO:0032446 342 0.013
regulation of mapk cascade GO:0043408 262 0.013
positive regulation of cell death GO:0010942 263 0.013
protein localization to cell surface GO:0034394 28 0.013
positive regulation of gtpase activity GO:0043547 166 0.013
coagulation GO:0050817 78 0.013
blastoderm segmentation GO:0007350 2 0.013
positive regulation of response to external stimulus GO:0032103 88 0.013
guanosine containing compound metabolic process GO:1901068 244 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
neurological system process GO:0050877 163 0.013
positive regulation of developmental process GO:0051094 314 0.013
response to nutrient levels GO:0031667 81 0.013
regulation of protein complex assembly GO:0043254 147 0.013
protein oligomerization GO:0051259 173 0.013
epithelial cell differentiation GO:0030855 141 0.013
cell development GO:0048468 328 0.013
positive regulation of cellular catabolic process GO:0031331 284 0.013
negative regulation of protein processing GO:0010955 142 0.012
hormone transport GO:0009914 68 0.012
inorganic cation transmembrane transport GO:0098662 194 0.012
regulation of protein transport GO:0051223 213 0.012
cellular ion homeostasis GO:0006873 168 0.012
alcohol metabolic process GO:0006066 114 0.012
cellular lipid catabolic process GO:0044242 65 0.012
protein stabilization GO:0050821 64 0.012
ion homeostasis GO:0050801 230 0.012
regulation of establishment of protein localization to plasma membrane GO:0090003 30 0.012
cellular cation homeostasis GO:0030003 163 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.012
syncytium formation by plasma membrane fusion GO:0000768 2 0.012
sequestering of metal ion GO:0051238 24 0.012
myeloid cell differentiation GO:0030099 117 0.012
cell projection assembly GO:0030031 126 0.012
inner ear morphogenesis GO:0042472 4 0.012
oocyte differentiation GO:0009994 2 0.012
membrane lipid metabolic process GO:0006643 53 0.012
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.012
regulation of blood coagulation GO:0030193 42 0.012
regulation of protein maturation GO:1903317 150 0.012
regulation of protein localization to cell surface GO:2000008 15 0.012
icosanoid metabolic process GO:0006690 35 0.012
actin polymerization or depolymerization GO:0008154 56 0.012
negative regulation of cell proliferation GO:0008285 228 0.012
tissue homeostasis GO:0001894 63 0.012
compound eye development GO:0048749 1 0.012
innate immune response GO:0045087 178 0.012
cellular metal ion homeostasis GO:0006875 146 0.012
gtp catabolic process GO:0006184 237 0.012
regulation of cellular ketone metabolic process GO:0010565 50 0.012
positive regulation of nucleotide catabolic process GO:0030813 185 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.012
cellular response to lipid GO:0071396 127 0.012
oocyte development GO:0048599 1 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
negative regulation of kinase activity GO:0033673 106 0.012
cell part morphogenesis GO:0032990 137 0.012
fatty acid derivative metabolic process GO:1901568 35 0.012
regulation of hormone secretion GO:0046883 57 0.012
hemopoiesis GO:0030097 180 0.011
positive regulation of phosphorylation GO:0042327 394 0.011
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 24 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
cell projection morphogenesis GO:0048858 129 0.011
regulation of cytoskeleton organization GO:0051493 177 0.011
positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774 3 0.011
regulation of insulin secretion GO:0050796 33 0.011
response to tumor necrosis factor GO:0034612 76 0.011
regulation of metal ion transport GO:0010959 120 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
cellular response to organonitrogen compound GO:0071417 124 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
memory GO:0007613 3 0.011
regulation of kinase activity GO:0043549 314 0.011
zymogen activation GO:0031638 70 0.011
antigen processing and presentation GO:0019882 33 0.011
peptide secretion GO:0002790 51 0.011
glucose homeostasis GO:0042593 31 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
tissue migration GO:0090130 119 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
sequestering of calcium ion GO:0051208 17 0.011
regulation of cell morphogenesis GO:0022604 153 0.011
response to external biotic stimulus GO:0043207 261 0.011
lipid modification GO:0030258 84 0.011
immune system development GO:0002520 195 0.011
divalent metal ion transport GO:0070838 152 0.011
response to cytokine GO:0034097 232 0.011
blastocyst development GO:0001824 3 0.011
lipid biosynthetic process GO:0008610 177 0.010
nucleoside triphosphate catabolic process GO:0009143 394 0.010
small molecule catabolic process GO:0044282 92 0.010
cellular response to glucocorticoid stimulus GO:0071385 4 0.010
proteasomal protein catabolic process GO:0010498 176 0.010
lipid catabolic process GO:0016042 84 0.010
regulation of actin filament based process GO:0032970 141 0.010
nuclear transport GO:0051169 179 0.010
regulation of protein processing GO:0070613 150 0.010
growth GO:0040007 202 0.010
establishment of protein localization to organelle GO:0072594 172 0.010
positive regulation of homeostatic process GO:0032846 47 0.010
positive regulation of cell adhesion GO:0045785 84 0.010
regulation of cell activation GO:0050865 125 0.010
endocytosis GO:0006897 159 0.010
Mouse
regulation of growth GO:0040008 165 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.010
response to metal ion GO:0010038 84 0.010
purine nucleoside monophosphate metabolic process GO:0009126 186 0.010
leukocyte mediated cytotoxicity GO:0001909 27 0.010
positive regulation of hormone secretion GO:0046887 25 0.010
regulation of peptide transport GO:0090087 62 0.010
cation transmembrane transport GO:0098655 238 0.010

VAMP8 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.037
inherited metabolic disorder DOID:655 242 0.037
immune system disease DOID:2914 155 0.030
central nervous system disease DOID:331 186 0.026
nervous system disease DOID:863 431 0.026
cancer DOID:162 167 0.020
disease of cellular proliferation DOID:14566 174 0.020
organ system cancer DOID:0050686 164 0.014
sensory system disease DOID:0050155 203 0.011
musculoskeletal system disease DOID:17 223 0.010
brain disease DOID:936 73 0.010