|
mitochondrion organization
|
GO:0007005 |
156 |
0.997
|
Fly |
|
regeneration
|
GO:0031099 |
4 |
0.962
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.947
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.929
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.921
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.817
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.747
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.745
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.737
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.721
|
Mouse Rat Fly |
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.717
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.706
|
|
|
mitochondrial membrane organization
|
GO:0007006 |
40 |
0.697
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.690
|
|
|
mitochondrial transport
|
GO:0006839 |
60 |
0.690
|
Rat |
|
cation homeostasis
|
GO:0055080 |
189 |
0.655
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.642
|
|
|
cation transport
|
GO:0006812 |
331 |
0.620
|
Rat |
|
glutamate metabolic process
|
GO:0006536 |
10 |
0.549
|
|
|
phototransduction
|
GO:0007602 |
3 |
0.523
|
Fly |
|
ion homeostasis
|
GO:0050801 |
230 |
0.506
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.487
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.475
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.474
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.471
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.471
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.455
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.450
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.415
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.411
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.409
|
|
|
detection of stimulus
|
GO:0051606 |
85 |
0.391
|
Fly |
|
metal ion transport
|
GO:0030001 |
272 |
0.387
|
Rat |
|
regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902108 |
18 |
0.366
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
68 |
0.364
|
|
|
protein import into mitochondrial matrix
|
GO:0030150 |
1 |
0.354
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.347
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.343
|
Fly |
|
post embryonic development
|
GO:0009791 |
2 |
0.330
|
|
|
response to topologically incorrect protein
|
GO:0035966 |
29 |
0.327
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.323
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.318
|
Mouse Rat Fly |
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.315
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.310
|
|
|
growth
|
GO:0040007 |
202 |
0.304
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.298
|
|
|
dna catabolic process
|
GO:0006308 |
49 |
0.293
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.292
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.277
|
|
|
endoplasmic reticulum unfolded protein response
|
GO:0030968 |
16 |
0.275
|
|
|
regulation of mitochondrial membrane permeability
|
GO:0046902 |
25 |
0.270
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.261
|
|
|
regulation of mitochondrial membrane potential
|
GO:0051881 |
23 |
0.260
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.259
|
|
|
negative regulation of protein polymerization
|
GO:0032272 |
16 |
0.245
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.238
|
Rat |
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.238
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.234
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.231
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.218
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.215
|
Fly |
|
protein processing
|
GO:0016485 |
226 |
0.212
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.212
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.206
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.202
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.197
|
Rat |
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.193
|
Mouse |
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.190
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.190
|
Fly |
|
zymogen activation
|
GO:0031638 |
70 |
0.186
|
|
|
embryo development
|
GO:0009790 |
123 |
0.185
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.181
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.179
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.179
|
Fly |
|
neurological system process
|
GO:0050877 |
163 |
0.177
|
Mouse |
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.176
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.174
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.168
|
|
|
wound healing
|
GO:0042060 |
115 |
0.168
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.165
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.157
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.155
|
Mouse |
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.147
|
|
|
anion transport
|
GO:0006820 |
161 |
0.145
|
Mouse Rat Fly |
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.143
|
Mouse Rat Fly |
|
membrane organization
|
GO:0061024 |
292 |
0.142
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.141
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.137
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.135
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.135
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.132
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.131
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.131
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.128
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.124
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.116
|
|
|
pyruvate metabolic process
|
GO:0006090 |
26 |
0.112
|
|
|
detection of light stimulus
|
GO:0009583 |
11 |
0.112
|
Fly |
|
ribonucleoside biosynthetic process
|
GO:0042455 |
25 |
0.111
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.111
|
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.111
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.109
|
Fly |
|
dicarboxylic acid biosynthetic process
|
GO:0043650 |
4 |
0.109
|
|
|
secretion
|
GO:0046903 |
254 |
0.109
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.108
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.108
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.107
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.106
|
Mouse Rat Fly |
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.103
|
Rat |
|
reproduction
|
GO:0000003 |
63 |
0.103
|
Fly |
|
activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c
|
GO:0008635 |
2 |
0.102
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.102
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.101
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.101
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
54 |
0.100
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.099
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.096
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
79 |
0.095
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.095
|
|
|
dicarboxylic acid catabolic process
|
GO:0043649 |
9 |
0.092
|
|
|
cell death in response to oxidative stress
|
GO:0036473 |
29 |
0.092
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.090
|
|
|
defense response
|
GO:0006952 |
315 |
0.090
|
Mouse |
|
single organism membrane fusion
|
GO:0044801 |
37 |
0.089
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.088
|
|
|
membrane fusion
|
GO:0061025 |
43 |
0.086
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.086
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.085
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.085
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.085
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.084
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.084
|
|
|
regulation of membrane permeability
|
GO:0090559 |
25 |
0.083
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.080
|
|
|
intracellular protein transmembrane import
|
GO:0044743 |
23 |
0.080
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.077
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.076
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.076
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.076
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.075
|
|
|
response to salt stress
|
GO:0009651 |
3 |
0.075
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.074
|
|
|
aging
|
GO:0007568 |
66 |
0.074
|
|
|
positive regulation of mitochondrion organization
|
GO:0010822 |
30 |
0.073
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.072
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.071
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.071
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.071
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.071
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.069
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.068
|
|
|
single organism carbohydrate catabolic process
|
GO:0044724 |
33 |
0.068
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.067
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.067
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.067
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.066
|
|
|
myosin filament assembly
|
GO:0031034 |
2 |
0.066
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.065
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.064
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.063
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.063
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.063
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.062
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.062
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.062
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.062
|
|
|
response to unfolded protein
|
GO:0006986 |
24 |
0.061
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.061
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.061
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.060
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.060
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.060
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.059
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.059
|
Fly |
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.058
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.058
|
|
|
hydrogen peroxide metabolic process
|
GO:0042743 |
20 |
0.058
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.058
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.057
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.057
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.056
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.055
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.055
|
Fly |
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.054
|
|
|
response to toxic substance
|
GO:0009636 |
37 |
0.054
|
|
|
response to drug
|
GO:0042493 |
81 |
0.054
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.054
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.053
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.053
|
Fly |
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.052
|
|
|
organic anion transport
|
GO:0015711 |
103 |
0.052
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.052
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.052
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.051
|
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
19 |
0.051
|
|
|
er nucleus signaling pathway
|
GO:0006984 |
23 |
0.051
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.051
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.051
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.050
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.050
|
|
|
mitochondrial fusion
|
GO:0008053 |
13 |
0.050
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.050
|
|
|
fear response
|
GO:0042596 |
0 |
0.050
|
Mouse |
|
release of cytochrome c from mitochondria
|
GO:0001836 |
35 |
0.049
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.049
|
|
|
glutamate biosynthetic process
|
GO:0006537 |
3 |
0.048
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.048
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.048
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.048
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.047
|
|
|
glutamine family amino acid biosynthetic process
|
GO:0009084 |
5 |
0.047
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.047
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.047
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.047
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.047
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.046
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.045
|
|
|
sleep
|
GO:0030431 |
2 |
0.045
|
|
|
cell aging
|
GO:0007569 |
52 |
0.045
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.045
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.045
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.045
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.044
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.044
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.044
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.043
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.043
|
Mouse |
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.043
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.042
|
|
|
regulation of release of cytochrome c from mitochondria
|
GO:0090199 |
29 |
0.042
|
|
|
cell development
|
GO:0048468 |
328 |
0.042
|
Fly |
|
alpha amino acid biosynthetic process
|
GO:1901607 |
23 |
0.042
|
|
|
protein targeting to mitochondrion
|
GO:0006626 |
19 |
0.041
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.041
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.041
|
|
|
cellular respiration
|
GO:0045333 |
21 |
0.041
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.041
|
|
|
organelle fusion
|
GO:0048284 |
36 |
0.041
|
|
|
necrotic cell death
|
GO:0070265 |
21 |
0.040
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.040
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.040
|
|
|
negative regulation of mitochondrion organization
|
GO:0010823 |
22 |
0.040
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.040
|
|
|
oxidoreduction coenzyme metabolic process
|
GO:0006733 |
19 |
0.039
|
|
|
muscle cell cellular homeostasis
|
GO:0046716 |
3 |
0.039
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.038
|
|
|
apoptotic nuclear changes
|
GO:0030262 |
13 |
0.038
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.038
|
|
|
male gamete generation
|
GO:0048232 |
22 |
0.038
|
Fly |
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.038
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.037
|
|
|
behavior
|
GO:0007610 |
112 |
0.037
|
Mouse |
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.036
|
|
|
mating
|
GO:0007618 |
1 |
0.036
|
|
|
positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902177 |
4 |
0.036
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.036
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.036
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.036
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.036
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.035
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.035
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.034
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.034
|
Fly |
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.034
|
|
|
inorganic anion transmembrane transport
|
GO:0098661 |
47 |
0.034
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.034
|
Fly |
|
negative regulation of binding
|
GO:0051100 |
57 |
0.033
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.033
|
|
|
response to hydrogen peroxide
|
GO:0042542 |
40 |
0.033
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.032
|
|
|
immune response
|
GO:0006955 |
307 |
0.032
|
|
|
intrinsic apoptotic signaling pathway in response to oxidative stress
|
GO:0008631 |
21 |
0.032
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.031
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.031
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.031
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.030
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
72 |
0.030
|
|
|
protein localization to mitochondrion
|
GO:0070585 |
25 |
0.030
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.030
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.029
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.029
|
|
|
regulation of oxidative stress induced cell death
|
GO:1903201 |
24 |
0.029
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.029
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.029
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.029
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.029
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.028
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.028
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.028
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.028
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.028
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.028
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.028
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.028
|
|
|
cellular response to unfolded protein
|
GO:0034620 |
16 |
0.028
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.028
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.027
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.027
|
|
|
nucleobase containing compound transport
|
GO:0015931 |
51 |
0.027
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.027
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.027
|
|
|
replicative cell aging
|
GO:0001302 |
3 |
0.027
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.027
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.027
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.027
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.027
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.026
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
43 |
0.026
|
|
|
protein refolding
|
GO:0042026 |
14 |
0.026
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.026
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.026
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.026
|
|
|
intracellular protein transmembrane transport
|
GO:0065002 |
24 |
0.026
|
|
|
spermatogenesis
|
GO:0007283 |
22 |
0.025
|
Fly |
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.025
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.025
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.025
|
|
|
atp synthesis coupled electron transport
|
GO:0042773 |
4 |
0.025
|
|
|
brain development
|
GO:0007420 |
97 |
0.025
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.025
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.024
|
|
|
coenzyme biosynthetic process
|
GO:0009108 |
24 |
0.024
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.024
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
22 |
0.024
|
|
|
glycosyl compound biosynthetic process
|
GO:1901659 |
27 |
0.024
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.024
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
26 |
0.024
|
|
|
regulation of atpase activity
|
GO:0043462 |
25 |
0.024
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.024
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.023
|
|
|
cell activation
|
GO:0001775 |
213 |
0.023
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.023
|
|
|
system process
|
GO:0003008 |
349 |
0.023
|
Mouse |
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.023
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
82 |
0.023
|
|
|
phosphate ion transport
|
GO:0006817 |
7 |
0.023
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.023
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.023
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.022
|
|
|
behavioral defense response
|
GO:0002209 |
0 |
0.022
|
Mouse |
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.022
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.022
|
Fly |
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.022
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.022
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.022
|
|
|
glutamine family amino acid metabolic process
|
GO:0009064 |
17 |
0.022
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.022
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.021
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.021
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.021
|
|
|
pigment biosynthetic process
|
GO:0046148 |
10 |
0.021
|
|
|
myosin filament organization
|
GO:0031033 |
2 |
0.021
|
|
|
regulation of neuron death
|
GO:1901214 |
56 |
0.021
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.021
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.021
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.021
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.021
|
|
|
establishment of protein localization to mitochondrion
|
GO:0072655 |
22 |
0.020
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.020
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.020
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.020
|
|
|
behavioral fear response
|
GO:0001662 |
0 |
0.020
|
Mouse |
|
alpha amino acid catabolic process
|
GO:1901606 |
26 |
0.020
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.020
|
|
|
cellular transition metal ion homeostasis
|
GO:0046916 |
21 |
0.020
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.020
|
|
|
positive regulation of cellular response to oxidative stress
|
GO:1900409 |
7 |
0.020
|
|
|
carbohydrate catabolic process
|
GO:0016052 |
36 |
0.020
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.020
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.020
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.020
|
|
|
nicotinamide nucleotide metabolic process
|
GO:0046496 |
14 |
0.020
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.020
|
|
|
cell differentiation in spinal cord
|
GO:0021515 |
1 |
0.019
|
|
|
rna catabolic process
|
GO:0006401 |
71 |
0.019
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.019
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.019
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.019
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.019
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.019
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.019
|
|
|
small molecule catabolic process
|
GO:0044282 |
92 |
0.019
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.019
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.019
|
|
|
neuron death
|
GO:0070997 |
65 |
0.019
|
|
|
monovalent inorganic cation homeostasis
|
GO:0055067 |
37 |
0.019
|
|
|
rna interference
|
GO:0016246 |
4 |
0.018
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.018
|
|
|
protein transmembrane transport
|
GO:0071806 |
25 |
0.018
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.018
|
|
|
negative regulation of signal transduction in absence of ligand
|
GO:1901099 |
16 |
0.018
|
|
|
carboxylic acid catabolic process
|
GO:0046395 |
71 |
0.018
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.018
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.018
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.018
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.018
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.017
|
Fly |
|
protein targeting
|
GO:0006605 |
187 |
0.017
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.017
|
|
|
phosphate ion transmembrane transport
|
GO:0035435 |
4 |
0.017
|
|
|
mitochondrial fission
|
GO:0000266 |
14 |
0.017
|
|
|
execution phase of apoptosis
|
GO:0097194 |
32 |
0.017
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.017
|
|
|
positive regulation of release of cytochrome c from mitochondria
|
GO:0090200 |
18 |
0.017
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.017
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.017
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.017
|
|
|
hypothalamus development
|
GO:0021854 |
1 |
0.017
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.017
|
|
|
tube development
|
GO:0035295 |
125 |
0.017
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.016
|
|
|
dicarboxylic acid metabolic process
|
GO:0043648 |
29 |
0.016
|
|
|
positive regulation of oxidative stress induced cell death
|
GO:1903209 |
5 |
0.016
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.016
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.016
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.016
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
35 |
0.016
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.016
|
|
|
response to virus
|
GO:0009615 |
126 |
0.016
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.016
|
|
|
detection of abiotic stimulus
|
GO:0009582 |
15 |
0.016
|
Fly |
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.016
|
|
|
cell growth
|
GO:0016049 |
160 |
0.016
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.016
|
|
|
urate metabolic process
|
GO:0046415 |
11 |
0.016
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.016
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.016
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.016
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.016
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.015
|
|
|
response to cocaine
|
GO:0042220 |
1 |
0.015
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.015
|
|
|
negative regulation of protein binding
|
GO:0032091 |
35 |
0.015
|
|
|
neuron apoptotic process
|
GO:0051402 |
39 |
0.015
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.015
|
|
|
nucleoside triphosphate biosynthetic process
|
GO:0009142 |
20 |
0.015
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.015
|
|
|
organic acid transport
|
GO:0015849 |
65 |
0.015
|
|
|
carboxylic acid transport
|
GO:0046942 |
63 |
0.015
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.014
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
43 |
0.014
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.014
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.014
|
|
|
fertilization
|
GO:0009566 |
12 |
0.014
|
|
|
mitochondrial calcium ion homeostasis
|
GO:0051560 |
11 |
0.014
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
22 |
0.014
|
|
|
cellular response to nutrient
|
GO:0031670 |
12 |
0.014
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.014
|
|
|
organic acid catabolic process
|
GO:0016054 |
71 |
0.014
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.014
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.014
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.014
|
|
|
protein import
|
GO:0017038 |
130 |
0.014
|
|
|
binding of sperm to zona pellucida
|
GO:0007339 |
3 |
0.014
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.014
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.014
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.014
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.014
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.014
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.014
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.014
|
|
|
anion transmembrane transport
|
GO:0098656 |
76 |
0.014
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.013
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.013
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.013
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.013
|
|
|
viral process
|
GO:0016032 |
146 |
0.013
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.013
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.013
|
|
|
amide transport
|
GO:0042886 |
76 |
0.013
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.013
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.013
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.013
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.013
|
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.013
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.013
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.013
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.013
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.013
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.013
|
|
|
head development
|
GO:0060322 |
108 |
0.013
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.013
|
|