|
|
negative regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060633 |
3 |
0.999
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.991
|
Human |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.989
|
|
|
|
epithelial cell fate commitment
|
GO:0072148 |
3 |
0.934
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.919
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.902
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.895
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.885
|
Human |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.884
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.875
|
|
|
|
midgut development
|
GO:0007494 |
1 |
0.873
|
|
|
|
regulation of transcription involved in lymphatic endothelial cell fate commitment
|
GO:0060849 |
2 |
0.857
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.857
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.844
|
|
|
|
hormone mediated signaling pathway
|
GO:0009755 |
22 |
0.824
|
Human |
|
|
chromatin modification
|
GO:0016568 |
298 |
0.818
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.812
|
Human |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.806
|
Rat |
|
|
intracellular bile acid receptor signaling pathway
|
GO:0038185 |
1 |
0.776
|
Human |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.773
|
|
|
|
positive regulation of interleukin 5 production
|
GO:0032754 |
3 |
0.773
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.768
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.711
|
Human |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.686
|
Human |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.675
|
Rat |
|
|
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus
|
GO:1901522 |
2 |
0.654
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.648
|
Mouse |
|
|
epithelium development
|
GO:0060429 |
227 |
0.639
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.638
|
Human |
|
|
demethylation
|
GO:0070988 |
37 |
0.616
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.597
|
Human Mouse |
|
|
response to lipid
|
GO:0033993 |
206 |
0.581
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.580
|
Human |
|
|
lymphatic endothelial cell fate commitment
|
GO:0060838 |
2 |
0.571
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.569
|
|
|
|
histone demethylation
|
GO:0016577 |
15 |
0.566
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
14 |
0.517
|
|
|
|
aldehyde biosynthetic process
|
GO:0046184 |
3 |
0.503
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.499
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.496
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.486
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.484
|
|
|
|
outflow tract septum morphogenesis
|
GO:0003148 |
4 |
0.463
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.455
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.449
|
|
|
|
protein demethylation
|
GO:0006482 |
17 |
0.436
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.416
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.416
|
Human Mouse |
|
|
protein dealkylation
|
GO:0008214 |
17 |
0.390
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.388
|
Human |
|
|
response to hormone
|
GO:0009725 |
175 |
0.376
|
Human Rat |
|
|
response to bacterium
|
GO:0009617 |
144 |
0.376
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.375
|
|
|
|
glandular epithelial cell differentiation
|
GO:0002067 |
6 |
0.368
|
|
|
|
histone h3 k9 demethylation
|
GO:0033169 |
7 |
0.360
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.349
|
Mouse |
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
4 |
0.343
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.341
|
Human |
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.331
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.330
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.315
|
Human |
|
|
negative regulation of cholesterol storage
|
GO:0010887 |
4 |
0.308
|
Human |
|
|
cell activation
|
GO:0001775 |
213 |
0.305
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.305
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.303
|
Mouse |
|
|
defense response
|
GO:0006952 |
315 |
0.303
|
Human |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.301
|
Human |
|
|
response to vitamin d
|
GO:0033280 |
10 |
0.301
|
|
|
|
negative regulation of rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0017055 |
2 |
0.297
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.287
|
|
|
|
cellular aldehyde metabolic process
|
GO:0006081 |
20 |
0.287
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.282
|
Human Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.281
|
|
|
|
prostate gland morphogenesis
|
GO:0060512 |
1 |
0.274
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.273
|
Human |
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.273
|
Human |
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.270
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.266
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.265
|
|
|
|
histone lysine demethylation
|
GO:0070076 |
14 |
0.264
|
|
|
|
receptor biosynthetic process
|
GO:0032800 |
18 |
0.264
|
Human |
|
|
cytokine production
|
GO:0001816 |
247 |
0.263
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.263
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.262
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.259
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.256
|
Human |
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.247
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.246
|
|
|
|
prostate gland development
|
GO:0030850 |
3 |
0.245
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.243
|
Mouse |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.239
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.237
|
Human |
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.237
|
|
|
|
androgen receptor signaling pathway
|
GO:0030521 |
34 |
0.235
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.234
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.234
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.233
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.228
|
Human Rat |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.223
|
|
|
|
vitamin d receptor signaling pathway
|
GO:0070561 |
4 |
0.220
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.215
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.214
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.214
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.214
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.214
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.211
|
Mouse |
|
|
immune system development
|
GO:0002520 |
195 |
0.210
|
Human |
|
|
gland development
|
GO:0048732 |
48 |
0.210
|
Mouse |
|
|
ossification
|
GO:0001503 |
121 |
0.208
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.206
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.203
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.195
|
|
|
|
glandular epithelial cell development
|
GO:0002068 |
5 |
0.195
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.192
|
Human Rat |
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.191
|
|
|
|
negative regulation of bile acid biosynthetic process
|
GO:0070858 |
3 |
0.187
|
Human |
|
|
cell development
|
GO:0048468 |
328 |
0.186
|
Human Mouse |
|
|
protein heterooligomerization
|
GO:0051291 |
16 |
0.186
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.182
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.182
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.181
|
Human |
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.180
|
|
|
|
positive regulation of binding
|
GO:0051099 |
45 |
0.179
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.179
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.178
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.175
|
|
|
|
embryonic camera type eye morphogenesis
|
GO:0048596 |
2 |
0.173
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.172
|
Mouse |
|
|
regulation of t helper cell differentiation
|
GO:0045622 |
3 |
0.171
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.170
|
|
|
|
ornithine metabolic process
|
GO:0006591 |
3 |
0.170
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.170
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.168
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.167
|
Human |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.167
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.166
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.166
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.166
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.166
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.165
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.164
|
Human Mouse |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.163
|
Human |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.161
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.160
|
Human |
|
|
protein maturation
|
GO:0051604 |
233 |
0.160
|
Human |
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.157
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.155
|
Human Mouse Fly |
|
|
response to estrogen
|
GO:0043627 |
47 |
0.155
|
Rat |
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.154
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.153
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.152
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.151
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.151
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.151
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.149
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.148
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.147
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.147
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.146
|
Human |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.141
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.140
|
|
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.136
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.136
|
|
|
|
cardiac right ventricle formation
|
GO:0003219 |
1 |
0.136
|
|
|
|
regulation of granulocyte differentiation
|
GO:0030852 |
11 |
0.136
|
|
|
|
response to nutrient
|
GO:0007584 |
20 |
0.133
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.132
|
Human |
|
|
cardiac ventricle formation
|
GO:0003211 |
2 |
0.131
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.131
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.128
|
|
|
|
head development
|
GO:0060322 |
108 |
0.128
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.127
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.126
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.125
|
Human |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.123
|
Human |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.123
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.122
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.122
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.121
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.120
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.118
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.116
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.116
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.116
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.116
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.115
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.113
|
Human |
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.113
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.113
|
|
|
|
cellular response to nutrient
|
GO:0031670 |
12 |
0.113
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.111
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.111
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.110
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.109
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.109
|
|
|
|
regulation of cellular ketone metabolic process by regulation of transcription from rna polymerase ii promoter
|
GO:0072364 |
3 |
0.108
|
Human |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.107
|
|
|
|
aortic valve development
|
GO:0003176 |
3 |
0.105
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.103
|
Human |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.102
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.102
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.102
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.102
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.101
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.101
|
Mouse |
|
|
hepaticobiliary system development
|
GO:0061008 |
10 |
0.101
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.100
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.100
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.100
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.099
|
|
|
|
trophectodermal cell differentiation
|
GO:0001829 |
3 |
0.098
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.098
|
Mouse |
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.097
|
Human |
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.097
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.097
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.097
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.097
|
|
|
|
growth
|
GO:0040007 |
202 |
0.097
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.096
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
29 |
0.096
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.096
|
|
|
|
embryonic camera type eye formation
|
GO:0060900 |
2 |
0.095
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.094
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.093
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
43 |
0.093
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.093
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.092
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.092
|
|
|
|
modulation by virus of host morphology or physiology
|
GO:0019048 |
10 |
0.092
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.091
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.091
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.091
|
Human Fly |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.089
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.088
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.087
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.087
|
Human Mouse |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.087
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.087
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.087
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.087
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.086
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.086
|
|
|
|
regulation of transcription involved in cell fate commitment
|
GO:0060850 |
6 |
0.085
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.085
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.085
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.084
|
Human Mouse |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.084
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.084
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.083
|
|
|
|
negative regulation of granulocyte differentiation
|
GO:0030853 |
5 |
0.083
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.083
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.082
|
|
|
|
striated muscle cell proliferation
|
GO:0014855 |
7 |
0.082
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.082
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.082
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.081
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.081
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.080
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.080
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.079
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.079
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.078
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.078
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.078
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.077
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.077
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.077
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.077
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.077
|
Human |
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.076
|
|
|
|
negative regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903556 |
20 |
0.076
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.076
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.076
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.075
|
|
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
16 |
0.075
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.075
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.075
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.075
|
|
|
|
ventricular cardiac muscle cell differentiation
|
GO:0055012 |
1 |
0.075
|
|
|
|
female pregnancy
|
GO:0007565 |
17 |
0.074
|
|
|
|
transcription initiation from rna polymerase ii promoter
|
GO:0006367 |
27 |
0.074
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.074
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.074
|
|
|
|
growth plate cartilage development
|
GO:0003417 |
1 |
0.074
|
|
|
|
endothelial cell fate commitment
|
GO:0060839 |
3 |
0.073
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.073
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.072
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.072
|
Mouse Rat |
|
|
inflammatory response
|
GO:0006954 |
79 |
0.072
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.072
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.071
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.071
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.071
|
Human |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.070
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.070
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.070
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.069
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.069
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.069
|
Human |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.069
|
Human |
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.069
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.068
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.068
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.068
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.068
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.068
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.068
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.067
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.067
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.066
|
Human |
|
|
protein homotetramerization
|
GO:0051289 |
28 |
0.066
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.065
|
Human Mouse |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.065
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.065
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.065
|
Mouse |
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
25 |
0.065
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.064
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.064
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.064
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.064
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.064
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.063
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.063
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.063
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.063
|
|
|
|
negative regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014067 |
4 |
0.063
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.062
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.062
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.062
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.062
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.061
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.061
|
Human Mouse |
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.061
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.061
|
|
|
|
regulation of t helper 2 cell differentiation
|
GO:0045628 |
1 |
0.061
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.061
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.061
|
Human |
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.060
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
4 |
0.060
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.060
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.060
|
|
|
|
cellular response to extracellular stimulus
|
GO:0031668 |
72 |
0.059
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.059
|
|
|
|
liver development
|
GO:0001889 |
9 |
0.059
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.059
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.058
|
Human |
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
26 |
0.058
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.057
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.057
|
Human |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.057
|
|
|
|
type 2 immune response
|
GO:0042092 |
6 |
0.057
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
16 |
0.056
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.056
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.056
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.056
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.056
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.056
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.054
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.054
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.053
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.053
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.053
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.053
|
|
|
|
chondroblast differentiation
|
GO:0060591 |
2 |
0.053
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.052
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.052
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.052
|
|
|
|
cell proliferation involved in heart valve development
|
GO:2000793 |
1 |
0.052
|
|
|
|
tube closure
|
GO:0060606 |
3 |
0.051
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.051
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.051
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.050
|
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.050
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.050
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.050
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.050
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.050
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.049
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.049
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.049
|
Human |
|
|
translational initiation
|
GO:0006413 |
48 |
0.048
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.048
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.048
|
|
|
|
formaldehyde metabolic process
|
GO:0046292 |
1 |
0.048
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.048
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.048
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.048
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.047
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.047
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.047
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.047
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.047
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.047
|
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
35 |
0.047
|
|
|
|
lipid homeostasis
|
GO:0055088 |
39 |
0.047
|
Fly |
|
|
heart development
|
GO:0007507 |
95 |
0.047
|
Rat |
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.046
|
|
|
|
endocardial cushion development
|
GO:0003197 |
3 |
0.046
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.046
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.046
|
|
|
|
cardiac chamber formation
|
GO:0003207 |
2 |
0.045
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.045
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.045
|
|
|
|
steroid biosynthetic process
|
GO:0006694 |
46 |
0.045
|
Human Mouse |
|
|
lipid transport
|
GO:0006869 |
90 |
0.045
|
Human |
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.045
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.044
|
|
|
|
negative regulation of dna templated transcription initiation
|
GO:2000143 |
3 |
0.044
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.044
|
|
|
|
cartilage development involved in endochondral bone morphogenesis
|
GO:0060351 |
2 |
0.044
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.044
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.044
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.044
|
Human |
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.043
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.043
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.043
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.043
|
|
|
|
regulation of receptor biosynthetic process
|
GO:0010869 |
15 |
0.043
|
Human |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.043
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.043
|
Human |
|
|
stem cell development
|
GO:0048864 |
69 |
0.043
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.042
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
13 |
0.042
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.042
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.042
|
|
|
|
cardiac left ventricle formation
|
GO:0003218 |
1 |
0.042
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.042
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.041
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.041
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.041
|
|
|
|
blastocyst formation
|
GO:0001825 |
3 |
0.041
|
|
|
|
blood vessel maturation
|
GO:0001955 |
1 |
0.041
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.040
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.040
|
|
|
|
multicellular organismal response to stress
|
GO:0033555 |
1 |
0.040
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.040
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
1 |
0.040
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.040
|
Human |
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.040
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.040
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.039
|
Human |
|
|
lipid localization
|
GO:0010876 |
106 |
0.039
|
Human |
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.039
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.039
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.039
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.039
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.038
|
|
|
|
cardiac right ventricle morphogenesis
|
GO:0003215 |
3 |
0.038
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.038
|
|
|
|
histone serine phosphorylation
|
GO:0035404 |
4 |
0.038
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.038
|
|
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
2 |
0.038
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.038
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.038
|
|
|
|
lateral mesoderm development
|
GO:0048368 |
1 |
0.037
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.037
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.037
|
|
|
|
ventricular cardiac muscle tissue morphogenesis
|
GO:0055010 |
14 |
0.037
|
|
|
|
regulation of lipid transport by regulation of transcription from rna polymerase ii promoter
|
GO:0072367 |
4 |
0.037
|
Human |
|
|
response to virus
|
GO:0009615 |
126 |
0.037
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.037
|
|
|
|
peroxisome proliferator activated receptor signaling pathway
|
GO:0035357 |
7 |
0.037
|
Human |
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.037
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.037
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.037
|
Human Mouse |
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
5 |
0.037
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.036
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.036
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.036
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.036
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.036
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.036
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
4 |
0.036
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.036
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.036
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.036
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.036
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.035
|
|
|
|
response to interferon gamma
|
GO:0034341 |
39 |
0.035
|
Human |
|
|
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia
|
GO:0061419 |
2 |
0.035
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.034
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.034
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.034
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.034
|
|
