Homo sapiens

124 known processes

VHL

von Hippel-Lindau tumor suppressor

(Aliases: VHL1,HRCA1,RCA1)

VHL biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of hormone biosynthetic process GO:0046886 4 0.993
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061419 2 0.977
cellular macromolecule catabolic process GO:0044265 380 0.932
Mouse
oogenesis GO:0048477 2 0.911
microtubule based movement GO:0007018 32 0.909
female gamete generation GO:0007292 2 0.901
regulation of cell cycle GO:0051726 393 0.813
response to nitric oxide GO:0071731 4 0.785
oxygen homeostasis GO:0032364 4 0.773
negative regulation of t cell apoptotic process GO:0070233 4 0.763
Mouse
regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0043619 5 0.728
cellular amino acid metabolic process GO:0006520 116 0.705
regulation of protein catabolic process GO:0042176 155 0.698
cyclic nucleotide catabolic process GO:0009214 9 0.686
regulation of meiotic cell cycle GO:0051445 4 0.686
protein catabolic process GO:0030163 325 0.678
Mouse
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 6 0.668
neural tube patterning GO:0021532 2 0.647
gas homeostasis GO:0033483 4 0.639
regulation of chromosome segregation GO:0051983 44 0.639
spinal cord dorsal ventral patterning GO:0021513 2 0.610
mitotic cell cycle process GO:1903047 286 0.605
cellular response to dna damage stimulus GO:0006974 379 0.601
segmentation GO:0035282 4 0.601
muscle structure development GO:0061061 98 0.582
regulation of cell cycle phase transition GO:1901987 126 0.546
phospholipid catabolic process GO:0009395 12 0.538
ventral spinal cord interneuron differentiation GO:0021514 1 0.515
positive regulation of proteolysis GO:0045862 142 0.509
cell morphogenesis GO:0000902 296 0.505
Worm
protein maturation GO:0051604 233 0.495
regulation of proteolysis GO:0030162 293 0.488
anterior posterior axis specification GO:0009948 2 0.479
protein modification by small protein conjugation GO:0032446 342 0.479
blastoderm segmentation GO:0007350 2 0.477
positive regulation of protein catabolic process GO:0045732 75 0.475
chemical homeostasis GO:0048878 306 0.450
cell fate commitment involved in pattern specification GO:0060581 1 0.436
cell type specific apoptotic process GO:0097285 125 0.433
Mouse
cell division GO:0051301 168 0.427
regulation of proteasomal protein catabolic process GO:0061136 87 0.423
anatomical structure formation involved in morphogenesis GO:0048646 284 0.421
Mouse
negative regulation of thymocyte apoptotic process GO:0070244 1 0.420
Mouse
positive regulation of programmed cell death GO:0043068 249 0.411
cell morphogenesis involved in differentiation GO:0000904 144 0.411
Worm
regulation of cell cycle process GO:0010564 266 0.390
cell differentiation in spinal cord GO:0021515 1 0.387
axon cargo transport GO:0008088 2 0.376
regulation of oxidative stress induced cell death GO:1903201 24 0.369
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.362
glial cell migration GO:0008347 4 0.345
cellular component morphogenesis GO:0032989 314 0.341
Worm
regulation of interleukin 5 secretion GO:2000662 2 0.338
regulation of mitotic cell cycle GO:0007346 189 0.338
cellular amine metabolic process GO:0044106 41 0.337
negative regulation of catalytic activity GO:0043086 335 0.336
positive regulation of meiotic cell cycle GO:0051446 2 0.332
positive regulation of apoptotic process GO:0043065 246 0.323
peptidyl tyrosine modification GO:0018212 170 0.323
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.317
cell cycle phase transition GO:0044770 173 0.313
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.312
spinal cord development GO:0021510 4 0.309
mitotic cell cycle GO:0000278 326 0.309
thymocyte apoptotic process GO:0070242 2 0.306
Mouse
mitotic cell cycle phase transition GO:0044772 162 0.304
negative regulation of lymphocyte apoptotic process GO:0070229 8 0.301
Mouse
wnt signaling pathway GO:0016055 156 0.301
regulation of cellular response to stress GO:0080135 244 0.299
mitotic sister chromatid separation GO:0051306 18 0.298
positive regulation of catabolic process GO:0009896 310 0.297
camp catabolic process GO:0006198 8 0.296
generation of neurons GO:0048699 152 0.292
Worm
positive regulation of cell cycle GO:0045787 140 0.292
chromosome separation GO:0051304 23 0.292
regulation of cell division GO:0051302 116 0.290
neuron development GO:0048666 113 0.288
Worm
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.288
neuron death in response to oxidative stress GO:0036475 9 0.286
multicellular organismal aging GO:0010259 3 0.283
Worm
response to nitrogen compound GO:1901698 184 0.282
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.281
Mouse
neuron apoptotic process GO:0051402 39 0.275
negative regulation of wnt signaling pathway GO:0030178 69 0.274
chemotaxis GO:0006935 157 0.273
Worm
modification dependent protein catabolic process GO:0019941 209 0.269
positive regulation of cell death GO:0010942 263 0.265
heat acclimation GO:0010286 3 0.262
response to cytokine GO:0034097 232 0.257
cytokine mediated signaling pathway GO:0019221 109 0.254
pituitary gland development GO:0021983 2 0.254
mitotic sister chromatid segregation GO:0000070 53 0.251
regulation of neuron apoptotic process GO:0043523 35 0.250
cytokine production GO:0001816 247 0.250
cyclin catabolic process GO:0008054 6 0.248
cytoskeleton dependent intracellular transport GO:0030705 21 0.243
single organism cellular localization GO:1902580 332 0.242
Mouse
meiotic chromosome segregation GO:0045132 4 0.242
regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061418 7 0.241
positive regulation of mitotic cell cycle GO:0045931 60 0.241
negative regulation of response to oxidative stress GO:1902883 18 0.239
negative regulation of phosphate metabolic process GO:0045936 267 0.233
protein processing GO:0016485 226 0.232
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.231
taxis GO:0042330 157 0.230
Worm
regulation of glucosylceramide catabolic process GO:2000752 1 0.230
maintenance of location GO:0051235 112 0.230
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.229
cell development GO:0048468 328 0.225
Worm
nervous system development GO:0007399 293 0.225
Worm
regulation of gtpase activity GO:0043087 180 0.225
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.225
positive regulation of cell cycle process GO:0090068 106 0.223
regulation of oxidative stress induced neuron death GO:1903203 9 0.222
response to hypoxia GO:0001666 96 0.217
anterior posterior axis specification embryo GO:0008595 2 0.212
purine nucleotide catabolic process GO:0006195 405 0.210
cuticle development GO:0042335 1 0.206
regulation of sister chromatid segregation GO:0033045 27 0.204
regulation of canonical wnt signaling pathway GO:0060828 88 0.202
epithelium migration GO:0090132 119 0.202
Mouse
negative regulation of lipid catabolic process GO:0050995 9 0.201
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.200
positive regulation of cytokine production GO:0001819 167 0.198
connective tissue replacement involved in inflammatory response wound healing GO:0002248 1 0.198
amine metabolic process GO:0009308 44 0.197
positive regulation of proteasomal protein catabolic process GO:1901800 35 0.197
protein hydroxylation GO:0018126 9 0.197
metaphase anaphase transition of cell cycle GO:0044784 21 0.196
cell projection organization GO:0030030 252 0.196
Worm
regulation of cellular protein catabolic process GO:1903362 96 0.195
regulation of protein ubiquitination GO:0031396 95 0.194
response to activity GO:0014823 0 0.194
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.193
muscle cell fate commitment GO:0042693 4 0.190
neuronal stem cell division GO:0036445 1 0.190
modification dependent macromolecule catabolic process GO:0043632 212 0.190
response to abiotic stimulus GO:0009628 336 0.188
positive regulation of cellular component organization GO:0051130 376 0.188
hypoxia inducible factor 1alpha signaling pathway GO:0097411 3 0.183
sister chromatid segregation GO:0000819 54 0.179
regulation of nuclear division GO:0051783 65 0.179
negative regulation of protein metabolic process GO:0051248 391 0.179
response to oxygen containing compound GO:1901700 369 0.178
interleukin 13 secretion GO:0072611 2 0.176
regulation of mitotic cell cycle phase transition GO:1901990 118 0.176
cellular response to cytokine stimulus GO:0071345 181 0.174
regulation of cellular component biogenesis GO:0044087 281 0.174
cellular homeostasis GO:0019725 196 0.174
regulation of ubiquitin protein transferase activity GO:0051438 28 0.172
cardiovascular system development GO:0072358 262 0.171
Mouse
cell projection morphogenesis GO:0048858 129 0.165
Worm
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.165
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.165
regulation of cellular ketone metabolic process GO:0010565 50 0.164
neuron projection development GO:0031175 106 0.163
Worm
ubiquitin dependent protein catabolic process GO:0006511 206 0.163
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.162
epithelium development GO:0060429 227 0.162
asymmetric neuroblast division GO:0055059 1 0.161
positive regulation of hydrolase activity GO:0051345 331 0.159
regulation of wnt signaling pathway GO:0030111 123 0.159
regulation of mitosis GO:0007088 63 0.157
neuron differentiation GO:0030182 138 0.156
Worm
regulation of ligase activity GO:0051340 29 0.155
retina vasculature development in camera type eye GO:0061298 3 0.155
neural tube formation GO:0001841 3 0.153
cellular protein catabolic process GO:0044257 261 0.151
Mouse
chordate embryonic development GO:0043009 34 0.151
nucleoside phosphate catabolic process GO:1901292 412 0.150
negative regulation of phosphorus metabolic process GO:0010563 267 0.149
neurogenesis GO:0022008 169 0.149
Worm
neuron projection morphogenesis GO:0048812 50 0.148
Worm
negative regulation of oxidative stress induced cell death GO:1903202 17 0.148
post embryonic development GO:0009791 2 0.144
Worm
purine nucleoside triphosphate metabolic process GO:0009144 412 0.144
zymogen activation GO:0031638 70 0.144
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.144
negative regulation of neuron apoptotic process GO:0043524 23 0.143
tube development GO:0035295 125 0.143
regulation of hormone metabolic process GO:0032350 14 0.142
neuron death GO:0070997 65 0.141
cellular ketone metabolic process GO:0042180 80 0.140
lamellipodium organization GO:0097581 30 0.138
regulation of cellular component movement GO:0051270 334 0.137
cell cycle checkpoint GO:0000075 117 0.136
regulation of mitotic sister chromatid segregation GO:0033047 27 0.133
circulatory system development GO:0072359 262 0.133
Mouse
regulation of endopeptidase activity GO:0052548 170 0.132
transition metal ion homeostasis GO:0055076 31 0.132
negative regulation of cellular response to oxidative stress GO:1900408 18 0.132
tripartite regional subdivision GO:0007351 2 0.132
retinal ganglion cell axon guidance GO:0031290 2 0.131
negative regulation of catabolic process GO:0009895 104 0.131
mitochondrion organization GO:0007005 156 0.130
membrane hyperpolarization GO:0060081 1 0.129
organelle fission GO:0048285 149 0.128
muscle cell differentiation GO:0042692 63 0.128
response to muscle activity GO:0014850 0 0.128
organic hydroxy compound metabolic process GO:1901615 147 0.128
regulation of cellular amine metabolic process GO:0033238 11 0.127
negative regulation of cellular amine metabolic process GO:0033239 3 0.126
positive regulation of dna metabolic process GO:0051054 73 0.125
neuroblast proliferation GO:0007405 4 0.124
response to oxygen levels GO:0070482 100 0.124
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.123
Worm
single organism reproductive process GO:0044702 98 0.122
regulation of cellular amino acid metabolic process GO:0006521 6 0.122
positive regulation of peptidase activity GO:0010952 88 0.122
peptidyl tyrosine phosphorylation GO:0018108 170 0.120
behavior GO:0007610 112 0.120
response to decreased oxygen levels GO:0036293 96 0.120
cellular response to peptide hormone stimulus GO:0071375 56 0.119
neuron intrinsic apoptotic signaling pathway in response to oxidative stress GO:0036480 7 0.119
neuron fate commitment GO:0048663 2 0.119
embryonic morphogenesis GO:0048598 85 0.119
hindbrain development GO:0030902 3 0.118
lipid localization GO:0010876 106 0.116
blood vessel development GO:0001568 172 0.115
Mouse
organophosphate catabolic process GO:0046434 430 0.114
purine ribonucleotide catabolic process GO:0009154 404 0.113
ventral spinal cord interneuron fate commitment GO:0060579 1 0.113
regulation of chromosome organization GO:0033044 103 0.113
regulation of neuron death GO:1901214 56 0.112
positive regulation of cellular component biogenesis GO:0044089 158 0.112
regulation of peptidase activity GO:0052547 180 0.112
regulation of mitotic sister chromatid separation GO:0010965 27 0.112
negative regulation of intracellular signal transduction GO:1902532 183 0.112
protein ubiquitination GO:0016567 314 0.112
vesicle mediated transport GO:0016192 371 0.111
biological adhesion GO:0022610 331 0.111
regulation of reactive oxygen species metabolic process GO:2000377 41 0.110
mitotic nuclear division GO:0007067 119 0.110
muscle cell cellular homeostasis GO:0046716 3 0.107
ventral spinal cord development GO:0021517 1 0.106
regulation of establishment of protein localization GO:0070201 242 0.104
hemoglobin biosynthetic process GO:0042541 3 0.104
purine containing compound catabolic process GO:0072523 411 0.103
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.103
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.103
hormone biosynthetic process GO:0042446 22 0.103
embryo development ending in birth or egg hatching GO:0009792 34 0.102
regulation of interleukin 13 secretion GO:2000665 2 0.102
embryo development GO:0009790 123 0.101
cell part morphogenesis GO:0032990 137 0.101
Worm
regulation of cysteine type endopeptidase activity GO:2000116 127 0.100
vasculature development GO:0001944 181 0.097
Mouse
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.096
determination of adult lifespan GO:0008340 2 0.096
Worm
leukocyte apoptotic process GO:0071887 31 0.096
Mouse
maintenance of location in cell GO:0051651 62 0.095
actin cytoskeleton organization GO:0030036 207 0.095
metencephalon development GO:0022037 2 0.094
chromosome segregation GO:0007059 114 0.093
canonical wnt signaling pathway GO:0060070 116 0.093
positive regulation of cell differentiation GO:0045597 211 0.092
establishment of organelle localization GO:0051656 59 0.092
negative regulation of kinase activity GO:0033673 106 0.091
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.091
axonogenesis GO:0007409 31 0.089
Worm
cellular protein complex assembly GO:0043623 188 0.089
regulation of anatomical structure size GO:0090066 101 0.089
wound healing involved in inflammatory response GO:0002246 2 0.088
nuclear migration GO:0007097 1 0.088
interleukin 5 secretion GO:0072603 2 0.087
positive regulation of cellular amine metabolic process GO:0033240 7 0.087
regulation of transferase activity GO:0051338 355 0.086
regulation of cell migration GO:0030334 289 0.086
positive regulation of cell cycle phase transition GO:1901989 22 0.085
regulation of cell growth GO:0001558 135 0.085
negative regulation of cellular protein metabolic process GO:0032269 353 0.082
intrinsic apoptotic signaling pathway GO:0097193 127 0.082
reproductive process GO:0022414 106 0.081
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.081
negative regulation of cellular catabolic process GO:0031330 83 0.081
stem cell division GO:0017145 2 0.081
microtubule based process GO:0007017 210 0.080
regulation of purine nucleotide catabolic process GO:0033121 205 0.079
ciliary neurotrophic factor mediated signaling pathway GO:0070120 5 0.077
negative regulation of oxidative stress induced neuron death GO:1903204 7 0.076
negative regulation of cell death GO:0060548 345 0.076
Mouse
response to oxidative stress GO:0006979 121 0.076
negative regulation of neuron death GO:1901215 32 0.075
ion homeostasis GO:0050801 230 0.075
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.074
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.074
phospholipid transport GO:0015914 23 0.074
cell growth GO:0016049 160 0.073
angiogenesis GO:0001525 147 0.073
Mouse
endocrine system development GO:0035270 26 0.073
microtubule based transport GO:0010970 21 0.072
hormone metabolic process GO:0042445 61 0.072
heart formation GO:0060914 2 0.071
nuclear division GO:0000280 128 0.071
ribonucleotide catabolic process GO:0009261 405 0.071
actin filament organization GO:0007015 128 0.070
regulation of cellular component size GO:0032535 82 0.070
single organism membrane organization GO:0044802 268 0.069
regulation of kinase activity GO:0043549 314 0.068
spindle elongation GO:0051231 4 0.068
transforming growth factor beta production GO:0071604 14 0.068
brain morphogenesis GO:0048854 1 0.068
cellular response to hypoxia GO:0071456 51 0.067
regulation of protein processing GO:0070613 150 0.066
elastin metabolic process GO:0051541 1 0.066
negative regulation of protein catabolic process GO:0042177 59 0.065
nucleotide catabolic process GO:0009166 408 0.065
vascular endothelial growth factor production GO:0010573 15 0.065
regulation of protein localization to plasma membrane GO:1903076 40 0.065
regulation of apoptotic signaling pathway GO:2001233 175 0.065
Mouse
epithelial cell differentiation GO:0030855 141 0.064
embryonic placenta development GO:0001892 1 0.064
cellular response to peptide GO:1901653 59 0.064
response to reactive oxygen species GO:0000302 61 0.062
monocarboxylic acid metabolic process GO:0032787 185 0.062
regulation of cyclic nucleotide phosphodiesterase activity GO:0051342 4 0.062
regulation of cell cycle g1 s phase transition GO:1902806 42 0.061
glycosyl compound catabolic process GO:1901658 413 0.061
regulation of response to oxidative stress GO:1902882 26 0.061
sensory perception of chemical stimulus GO:0007606 38 0.061
organelle localization GO:0051640 84 0.061
cellular response to starvation GO:0009267 58 0.061
negative regulation of protein phosphorylation GO:0001933 140 0.060
regulation of cellular response to oxidative stress GO:1900407 26 0.060
regulation of purine nucleotide metabolic process GO:1900542 264 0.060
positive regulation of cellular catabolic process GO:0031331 284 0.060
receptor biosynthetic process GO:0032800 18 0.059
positive regulation vascular endothelial growth factor production GO:0010575 12 0.059
positive regulation of glucosylceramide catabolic process GO:2000753 1 0.059
positive regulation of protein phosphorylation GO:0001934 313 0.059
endothelial cell migration GO:0043542 86 0.058
Mouse
cellular cation homeostasis GO:0030003 163 0.058
lymphocyte homeostasis GO:0002260 4 0.058
defense response GO:0006952 315 0.058
spinal cord patterning GO:0021511 2 0.058
4 hydroxyproline metabolic process GO:0019471 5 0.057
small gtpase mediated signal transduction GO:0007264 78 0.057
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.057
tube morphogenesis GO:0035239 95 0.056
cell cycle g1 s phase transition GO:0044843 80 0.056
asymmetric stem cell division GO:0098722 1 0.056
ribonucleoside triphosphate catabolic process GO:0009203 391 0.055
purine ribonucleoside metabolic process GO:0046128 437 0.055
digestive tract development GO:0048565 75 0.055
negative regulation of developmental process GO:0051093 247 0.055
proteasomal protein catabolic process GO:0010498 176 0.055
Mouse
response to interleukin 1 GO:0070555 47 0.055
negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903377 5 0.054
regulation of cytokine production GO:0001817 232 0.054
gland development GO:0048732 48 0.053
nerve development GO:0021675 4 0.053
abducens nerve development GO:0021560 1 0.052
regulation of generation of precursor metabolites and energy GO:0043467 27 0.052
positive regulation of sphingolipid biosynthetic process GO:0090154 1 0.052
cellular response to oxygen levels GO:0071453 55 0.052
positive regulation of cell development GO:0010720 92 0.052
negative regulation of proteolysis GO:0045861 132 0.051
positive regulation of transport GO:0051050 336 0.051
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 35 0.051
regulation of cell differentiation GO:0045595 393 0.051
response to virus GO:0009615 126 0.050
peptidyl proline modification GO:0018208 15 0.050
maintenance of protein location in cell GO:0032507 56 0.050
establishment of nucleus localization GO:0040023 1 0.050
regulation of meiosis GO:0040020 3 0.050
developmental process involved in reproduction GO:0003006 66 0.049
positive regulation of autophagy GO:0010508 24 0.049
cellular response to interleukin 1 GO:0071347 35 0.049
epithelial cell migration GO:0010631 119 0.049
Mouse
response to starvation GO:0042594 59 0.049
cellular response to toxic substance GO:0097237 4 0.049
activation of cysteine type endopeptidase activity GO:0097202 57 0.048
positive regulation of cellular protein catabolic process GO:1903364 37 0.048
organic anion transport GO:0015711 103 0.048
negative regulation of programmed cell death GO:0043069 321 0.048
Mouse
protein deubiquitination GO:0016579 79 0.048
negative regulation of apoptotic signaling pathway GO:2001234 97 0.048
regeneration GO:0031099 4 0.048
response to wounding GO:0009611 168 0.047
pattern specification process GO:0007389 43 0.047
purine nucleoside catabolic process GO:0006152 398 0.046
regulation of receptor biosynthetic process GO:0010869 15 0.046
positive regulation of epithelial cell migration GO:0010634 55 0.046
positive regulation of glycogen biosynthetic process GO:0045725 10 0.045
cell death in response to oxidative stress GO:0036473 29 0.045
regulation of growth GO:0040008 165 0.045
regulation of neural precursor cell proliferation GO:2000177 4 0.045
regulation of neurogenesis GO:0050767 82 0.044
blood vessel morphogenesis GO:0048514 162 0.044
Mouse
nucleoside triphosphate metabolic process GO:0009141 422 0.044
response to radiation GO:0009314 151 0.044
neuromuscular junction development GO:0007528 3 0.044
organelle assembly GO:0070925 176 0.044
meiosis i GO:0007127 4 0.044
cellular response to external stimulus GO:0071496 111 0.044
negative regulation of protein processing GO:0010955 142 0.043
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.042
regulation of nucleoside metabolic process GO:0009118 209 0.042
negative regulation of protein maturation GO:1903318 142 0.042
cation homeostasis GO:0055080 189 0.042
positive regulation of locomotion GO:0040017 186 0.042
cellular response to decreased oxygen levels GO:0036294 51 0.042
neuroblast division GO:0055057 1 0.042
hemoglobin metabolic process GO:0020027 3 0.042
response to auditory stimulus GO:0010996 4 0.042
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.041
cellular biogenic amine metabolic process GO:0006576 34 0.041
regulation of cell morphogenesis GO:0022604 153 0.041
response to organic cyclic compound GO:0014070 204 0.041
morphogenesis of a polarized epithelium GO:0001738 3 0.041
response to peptide GO:1901652 65 0.041
cellular metal ion homeostasis GO:0006875 146 0.041
axon transport of mitochondrion GO:0019896 2 0.040
gtp catabolic process GO:0006184 237 0.040
regulation of response to dna damage stimulus GO:2001020 94 0.040
neuron remodeling GO:0016322 2 0.040
morphogenesis of embryonic epithelium GO:0016331 4 0.040
neural tube development GO:0021915 9 0.040
response to extracellular stimulus GO:0009991 85 0.040
inflammatory response GO:0006954 79 0.040
membrane organization GO:0061024 292 0.039
positive regulation of transferase activity GO:0051347 227 0.039
regulation of nucleotide catabolic process GO:0030811 205 0.039
tissue migration GO:0090130 119 0.039
Mouse
negative regulation of ossification GO:0030279 21 0.039
positive regulation of cellular component movement GO:0051272 181 0.039
regulation of vasculature development GO:1901342 97 0.039
regulation of protein kinase activity GO:0045859 289 0.039
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.038
establishment of chromosome localization GO:0051303 20 0.038
regulation of response to external stimulus GO:0032101 222 0.038
regulation of interleukin 5 production GO:0032674 6 0.038
regulation of protein complex assembly GO:0043254 147 0.038
protein localization to organelle GO:0033365 280 0.038
Mouse
positive regulation of neuroblast proliferation GO:0002052 2 0.037
ribonucleoside triphosphate metabolic process GO:0009199 412 0.037
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.037
trabecula morphogenesis GO:0061383 2 0.037
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 20 0.037
regulation of autophagy GO:0010506 52 0.036
tissue morphogenesis GO:0048729 96 0.036
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.036
purine nucleoside triphosphate catabolic process GO:0009146 392 0.036
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 10 0.036
posttranscriptional regulation of gene expression GO:0010608 213 0.036
guanosine containing compound metabolic process GO:1901068 244 0.036
regulation of protein localization GO:0032880 296 0.036
multicellular organism reproduction GO:0032504 42 0.036
positive regulation of neural precursor cell proliferation GO:2000179 2 0.035
glucosylceramide metabolic process GO:0006678 3 0.035
reproduction GO:0000003 63 0.035
Worm
response to ionizing radiation GO:0010212 65 0.035
forebrain generation of neurons GO:0021872 3 0.035
sensory organ development GO:0007423 52 0.035
protein localization to plasma membrane GO:0072659 93 0.035
endocytosis GO:0006897 159 0.035
forebrain development GO:0030900 26 0.034
multi organism reproductive process GO:0044703 54 0.034
response to other organism GO:0051707 261 0.034
cellular carbohydrate metabolic process GO:0044262 84 0.034
regulation of anatomical structure morphogenesis GO:0022603 286 0.034
protein secretion GO:0009306 98 0.034
glucosylceramide catabolic process GO:0006680 2 0.033
motor neuron axon guidance GO:0008045 2 0.033
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 16 0.033
reactive nitrogen species metabolic process GO:2001057 3 0.033
ossification GO:0001503 121 0.033
autophagy GO:0006914 88 0.033
positive regulation of gliogenesis GO:0014015 4 0.033
regulation of nucleotide metabolic process GO:0006140 269 0.033
cytoplasmic transport GO:0016482 379 0.033
Mouse
somatic stem cell division GO:0048103 1 0.033
blood vessel remodeling GO:0001974 2 0.033
regulation of lymphocyte apoptotic process GO:0070228 15 0.033
Mouse
positive regulation of cell size GO:0045793 3 0.033
purine ribonucleoside catabolic process GO:0046130 398 0.032
regulation of hormone levels GO:0010817 125 0.032
peroxisome degradation GO:0030242 1 0.032
positive regulation of mitochondrial depolarization GO:0051901 3 0.032
lymphocyte apoptotic process GO:0070227 20 0.032
Mouse
liposaccharide metabolic process GO:1903509 27 0.032
lipid catabolic process GO:0016042 84 0.032
brain development GO:0007420 97 0.032
aging GO:0007568 66 0.032
Worm
positive regulation of interleukin 13 secretion GO:2000667 1 0.032
regulation of cell development GO:0060284 161 0.032
cellular response to oxygen containing compound GO:1901701 276 0.031
ribonucleoside catabolic process GO:0042454 406 0.031

VHL disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.053
sensory system disease DOID:0050155 203 0.038
eye and adnexa disease DOID:1492 150 0.038
nervous system disease DOID:863 431 0.038
eye disease DOID:5614 149 0.037
retinal disease DOID:5679 118 0.035
disease of metabolism DOID:0014667 295 0.032