Homo sapiens

115 known processes

VPS4A

vacuolar protein sorting 4 homolog A (S. cerevisiae)

(Aliases: SKD2,SKD1,FLJ22197,SKD1A,VPS4-1,VPS4)

VPS4A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to nutrient levels GO:0031669 69 0.178
Fly
cellular response to external stimulus GO:0071496 111 0.173
Fly
vesicle mediated transport GO:0016192 371 0.156
dna conformation change GO:0071103 113 0.143
mitotic cell cycle process GO:1903047 286 0.142
protein localization to organelle GO:0033365 280 0.124
Yeast
cytoplasmic transport GO:0016482 379 0.120
Human Yeast
oogenesis GO:0048477 2 0.111
cell division GO:0051301 168 0.096
cytokinesis GO:0000910 96 0.089
chromosome segregation GO:0007059 114 0.079
cellular response to nutrient GO:0031670 12 0.076
protein catabolic process GO:0030163 325 0.073
sister chromatid segregation GO:0000819 54 0.072
mitotic nuclear division GO:0007067 119 0.066
mitotic sister chromatid segregation GO:0000070 53 0.064
post embryonic development GO:0009791 2 0.063
single organism cellular localization GO:1902580 332 0.061
Yeast
small gtpase mediated signal transduction GO:0007264 78 0.060
regulation of cell cycle process GO:0010564 266 0.058
ras protein signal transduction GO:0007265 73 0.057
female gamete generation GO:0007292 2 0.057
nucleoside phosphate catabolic process GO:1901292 412 0.052
Human Yeast
nuclear division GO:0000280 128 0.049
cellular protein catabolic process GO:0044257 261 0.049
response to nutrient levels GO:0031667 81 0.049
Fly
dna packaging GO:0006323 77 0.048
macroautophagy GO:0016236 39 0.047
Fly
purine nucleoside triphosphate catabolic process GO:0009146 392 0.046
Human Yeast
positive regulation of hydrolase activity GO:0051345 331 0.044
membrane organization GO:0061024 292 0.044
organelle fission GO:0048285 149 0.044
cell development GO:0048468 328 0.043
nucleoside triphosphate metabolic process GO:0009141 422 0.042
Human Yeast
nucleoside triphosphate catabolic process GO:0009143 394 0.041
Human Yeast
protein targeting GO:0006605 187 0.041
intracellular protein transport GO:0006886 270 0.040
histone modification GO:0016570 251 0.040
negative regulation of protein metabolic process GO:0051248 391 0.038
ncrna metabolic process GO:0034660 108 0.038
cellular amino acid metabolic process GO:0006520 116 0.037
nucleotide catabolic process GO:0009166 408 0.036
Human Yeast
regulation of protein localization GO:0032880 296 0.035
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.035
locomotory behavior GO:0007626 1 0.035
single organism membrane organization GO:0044802 268 0.034
Yeast Fly
system process GO:0003008 349 0.034
actin cytoskeleton organization GO:0030036 207 0.033
Fly
axon cargo transport GO:0008088 2 0.033
regulation of transferase activity GO:0051338 355 0.033
regulation of cellular component biogenesis GO:0044087 281 0.033
oocyte differentiation GO:0009994 2 0.033
establishment of protein localization to organelle GO:0072594 172 0.033
modification dependent protein catabolic process GO:0019941 209 0.032
spermatid differentiation GO:0048515 4 0.032
purine nucleoside catabolic process GO:0006152 398 0.032
Human Yeast
purine nucleoside triphosphate metabolic process GO:0009144 412 0.031
Human Yeast
cellular response to starvation GO:0009267 58 0.031
Fly
regulation of cell cycle GO:0051726 393 0.031
cellular amine metabolic process GO:0044106 41 0.030
spermatid development GO:0007286 4 0.030
regulation of autophagy GO:0010506 52 0.030
negative regulation of cellular protein metabolic process GO:0032269 353 0.030
negative regulation of catalytic activity GO:0043086 335 0.029
nervous system development GO:0007399 293 0.028
secretion by cell GO:0032940 226 0.028
cellular macromolecule catabolic process GO:0044265 380 0.028
cell cell signaling GO:0007267 155 0.028
positive regulation of catabolic process GO:0009896 310 0.028
glycosyl compound catabolic process GO:1901658 413 0.028
Human Yeast
response to abiotic stimulus GO:0009628 336 0.027
purine ribonucleoside metabolic process GO:0046128 437 0.027
Human Yeast
positive regulation of transferase activity GO:0051347 227 0.026
oocyte development GO:0048599 1 0.026
chromatin modification GO:0016568 298 0.026
regulation of cellular amine metabolic process GO:0033238 11 0.025
mitotic cell cycle GO:0000278 326 0.025
regulation of cytoskeleton organization GO:0051493 177 0.025
actin filament based process GO:0030029 224 0.025
Fly
multicellular organismal aging GO:0010259 3 0.025
negative regulation of cellular component organization GO:0051129 235 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.025
Human Yeast
autophagy GO:0006914 88 0.024
Fly
regulation of cellular amino acid metabolic process GO:0006521 6 0.024
purine ribonucleotide catabolic process GO:0009154 404 0.024
Human Yeast
cell cycle checkpoint GO:0000075 117 0.024
rna processing GO:0006396 255 0.023
regulation of proteolysis GO:0030162 293 0.023
cellular protein complex assembly GO:0043623 188 0.023
protein acylation GO:0043543 138 0.023
cell projection organization GO:0030030 252 0.023
gtp catabolic process GO:0006184 237 0.022
positive regulation of transport GO:0051050 336 0.022
regulation of cellular response to stress GO:0080135 244 0.022
organonitrogen compound biosynthetic process GO:1901566 200 0.022
response to extracellular stimulus GO:0009991 85 0.022
Fly
guanosine containing compound metabolic process GO:1901068 244 0.022
regulation of protein kinase activity GO:0045859 289 0.021
negative regulation of phosphorus metabolic process GO:0010563 267 0.021
regulation of cell differentiation GO:0045595 393 0.021
response to nutrient GO:0007584 20 0.020
microtubule based process GO:0007017 210 0.020
protein oligomerization GO:0051259 173 0.020
Yeast
microtubule cytoskeleton organization GO:0000226 176 0.020
protein acetylation GO:0006473 116 0.020
negative regulation of cell cycle GO:0045786 193 0.020
ribonucleoside triphosphate catabolic process GO:0009203 391 0.020
Human Yeast
positive regulation of protein kinase activity GO:0045860 190 0.019
endomembrane system organization GO:0010256 196 0.019
positive regulation of cellular component organization GO:0051130 376 0.019
secretion GO:0046903 254 0.019
response to fungus GO:0009620 4 0.019
amine metabolic process GO:0009308 44 0.019
organelle assembly GO:0070925 176 0.019
proteasomal protein catabolic process GO:0010498 176 0.019
regulation of kinase activity GO:0043549 314 0.019
glycoprotein metabolic process GO:0009100 110 0.019
negative regulation of phosphate metabolic process GO:0045936 267 0.019
purine nucleoside monophosphate catabolic process GO:0009128 158 0.019
Human Yeast
modification dependent macromolecule catabolic process GO:0043632 212 0.018
regulation of ras protein signal transduction GO:0046578 155 0.018
negative regulation of protein modification process GO:0031400 200 0.018
purine ribonucleoside catabolic process GO:0046130 398 0.018
Human Yeast
negative regulation of phosphorylation GO:0042326 174 0.018
regulation of binding GO:0051098 111 0.018
cellular response to dna damage stimulus GO:0006974 379 0.017
negative regulation of protein phosphorylation GO:0001933 140 0.017
positive regulation of cellular amine metabolic process GO:0033240 7 0.017
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.017
Fly
determination of adult lifespan GO:0008340 2 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.017
Human Yeast
protein maturation GO:0051604 233 0.016
rna splicing GO:0008380 131 0.016
thymus development GO:0048538 3 0.016
positive regulation of phosphorylation GO:0042327 394 0.016
protein localization to membrane GO:0072657 160 0.016
organelle localization GO:0051640 84 0.016
regulation of intracellular transport GO:0032386 195 0.016
multicellular organismal reproductive process GO:0048609 40 0.016
protein targeting to nucleus GO:0044744 104 0.016
regulation of gtpase activity GO:0043087 180 0.016
regulation of cellular ketone metabolic process GO:0010565 50 0.016
lipid transport GO:0006869 90 0.016
Human
ribonucleoside triphosphate metabolic process GO:0009199 412 0.016
Human Yeast
reproductive process GO:0022414 106 0.016
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
nucleocytoplasmic transport GO:0006913 176 0.016
neurotransmitter secretion GO:0007269 4 0.016
segmentation GO:0035282 4 0.016
cell morphogenesis GO:0000902 296 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
positive regulation of gtpase activity GO:0043547 166 0.015
vesicle organization GO:0016050 62 0.015
cellular ketone metabolic process GO:0042180 80 0.015
positive regulation of cell differentiation GO:0045597 211 0.015
mapk cascade GO:0000165 288 0.015
protein localization to nucleus GO:0034504 136 0.015
guanosine containing compound catabolic process GO:1901069 239 0.015
gene silencing GO:0016458 49 0.015
behavior GO:0007610 112 0.015
negative regulation of response to external stimulus GO:0032102 83 0.015
positive regulation of nucleotide metabolic process GO:0045981 230 0.015
single organism reproductive process GO:0044702 98 0.015
regulation of cellular component movement GO:0051270 334 0.015
nuclear transport GO:0051169 179 0.015
negative regulation of cell proliferation GO:0008285 228 0.015
meiotic chromosome segregation GO:0045132 4 0.015
establishment of protein localization to membrane GO:0090150 121 0.014
innate immune response GO:0045087 178 0.014
regulation of nucleotide metabolic process GO:0006140 269 0.014
embryo development GO:0009790 123 0.014
positive regulation of cellular catabolic process GO:0031331 284 0.014
maintenance of location GO:0051235 112 0.014
Yeast
endochondral bone morphogenesis GO:0060350 3 0.014
ribonucleoprotein complex subunit organization GO:0071826 81 0.014
histone acetylation GO:0016573 93 0.014
nuclear import GO:0051170 106 0.014
endosomal transport GO:0016197 129 0.014
neuromuscular junction development GO:0007528 3 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.013
anterior posterior axis specification embryo GO:0008595 2 0.013
trna processing GO:0008033 23 0.013
neurogenesis GO:0022008 169 0.013
internal peptidyl lysine acetylation GO:0018393 97 0.013
regulation of cell development GO:0060284 161 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
positive regulation of proteolysis GO:0045862 142 0.013
negative regulation of cell cycle phase transition GO:1901988 89 0.013
protein import into nucleus GO:0006606 104 0.013
reproduction GO:0000003 63 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
regulation of actin cytoskeleton organization GO:0032956 116 0.013
positive regulation of protein phosphorylation GO:0001934 313 0.013
regulation of mitotic cell cycle phase transition GO:1901990 118 0.013
regulation of intracellular protein transport GO:0033157 123 0.013
response to starvation GO:0042594 59 0.013
Fly
regulation of nucleotide catabolic process GO:0030811 205 0.013
peptidyl lysine acetylation GO:0018394 101 0.013
ribonucleotide catabolic process GO:0009261 405 0.013
Human Yeast
cellular component morphogenesis GO:0032989 314 0.013
mitotic cell cycle phase transition GO:0044772 162 0.013
cell cycle phase transition GO:0044770 173 0.012
regulation of mitotic cell cycle GO:0007346 189 0.012
negative regulation of transport GO:0051051 176 0.012
Human
hematopoietic or lymphoid organ development GO:0048534 186 0.012
purine nucleoside monophosphate metabolic process GO:0009126 186 0.012
Human Yeast
regulation of purine nucleotide metabolic process GO:1900542 264 0.012
regulation of secretion by cell GO:1903530 177 0.012
compound eye development GO:0048749 1 0.012
positive regulation of kinase activity GO:0033674 204 0.012
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.012
protein deubiquitination GO:0016579 79 0.012
lipid localization GO:0010876 106 0.012
Human
negative regulation of organelle organization GO:0010639 126 0.012
response to oxygen containing compound GO:1901700 369 0.012
purine containing compound catabolic process GO:0072523 411 0.012
Human Yeast
regulation of protein complex assembly GO:0043254 147 0.012
gtp metabolic process GO:0046039 239 0.012
negative regulation of catabolic process GO:0009895 104 0.012
rho protein signal transduction GO:0007266 26 0.012
synaptic transmission GO:0007268 61 0.012
signal transduction by phosphorylation GO:0023014 297 0.012
negative regulation of intracellular signal transduction GO:1902532 183 0.011
regulation of response to external stimulus GO:0032101 222 0.011
establishment of nucleus localization GO:0040023 1 0.011
cell projection morphogenesis GO:0048858 129 0.011
organophosphate catabolic process GO:0046434 430 0.011
Human Yeast
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.011
Fly
inner ear morphogenesis GO:0042472 4 0.011
photoreceptor cell differentiation GO:0046530 2 0.011
positive regulation of camp biosynthetic process GO:0030819 35 0.011
negative regulation of cell death GO:0060548 345 0.011
macromolecular complex disassembly GO:0032984 60 0.011
positive regulation of cellular component movement GO:0051272 181 0.011
biological adhesion GO:0022610 331 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
regulation of protein catabolic process GO:0042176 155 0.011
regulation of nucleoside metabolic process GO:0009118 209 0.011
ribonucleoside catabolic process GO:0042454 406 0.011
Human Yeast
protein import GO:0017038 130 0.011
endocytosis GO:0006897 159 0.011
Fly
adult locomotory behavior GO:0008344 1 0.011
neurological system process GO:0050877 163 0.011
protein homooligomerization GO:0051260 100 0.011
Yeast
memory GO:0007613 3 0.011
trna modification GO:0006400 10 0.011
ncrna processing GO:0034470 83 0.011
peripheral nervous system development GO:0007422 2 0.011
covalent chromatin modification GO:0016569 254 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
positive regulation of cell death GO:0010942 263 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
lipid metabolic process GO:0006629 381 0.011
Yeast
positive regulation of organelle organization GO:0010638 195 0.011
positive regulation of gtp catabolic process GO:0033126 166 0.011
associative learning GO:0008306 1 0.011
negative regulation of cellular catabolic process GO:0031330 83 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
positive regulation of secretion by cell GO:1903532 108 0.011
protein ubiquitination GO:0016567 314 0.011
positive regulation of developmental process GO:0051094 314 0.011
carbon catabolite regulation of transcription GO:0045990 5 0.010
small molecule biosynthetic process GO:0044283 157 0.010
neuron development GO:0048666 113 0.010
regulation of map kinase activity GO:0043405 108 0.010
cell type specific apoptotic process GO:0097285 125 0.010
developmental process involved in reproduction GO:0003006 66 0.010
protein secretion GO:0009306 98 0.010
regulation of cell motility GO:2000145 299 0.010
cellular macromolecular complex assembly GO:0034622 324 0.010
regulation of cell cycle phase transition GO:1901987 126 0.010
cellular response to extracellular stimulus GO:0031668 72 0.010
Fly
negative regulation of protein maturation GO:1903318 142 0.010
chromosome condensation GO:0030261 15 0.010
positive regulation of programmed cell death GO:0043068 249 0.010
regulation of proteasomal protein catabolic process GO:0061136 87 0.010
regulation of peptidase activity GO:0052547 180 0.010

VPS4A disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.016
disease of cellular proliferation DOID:14566 174 0.014
myopathy DOID:423 104 0.013
muscular disease DOID:0080000 114 0.013
muscle tissue disease DOID:66 113 0.013
sensory system disease DOID:0050155 203 0.013
eye and adnexa disease DOID:1492 150 0.013
nervous system disease DOID:863 431 0.013
eye disease DOID:5614 149 0.013