Homo sapiens

97 known processes

WAPAL

wings apart-like homolog (Drosophila)

(Aliases: FOE,KIAA0261,WAPL)

WAPAL biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic sister chromatid cohesion GO:0007064 12 0.987
sister chromatid segregation GO:0000819 54 0.976
negative regulation of dna replication GO:0008156 29 0.976
dna replication GO:0006260 116 0.963
meiotic chromosome segregation GO:0045132 4 0.957
Fly
stem cell maintenance GO:0019827 19 0.909
stem cell differentiation GO:0048863 93 0.900
chromosome segregation GO:0007059 114 0.877
sister chromatid cohesion GO:0007062 24 0.861
mitotic sister chromatid segregation GO:0000070 53 0.840
regulation of dna metabolic process GO:0051052 153 0.832
post embryonic development GO:0009791 2 0.794
negative regulation of dna endoreduplication GO:0032876 5 0.786
stem cell development GO:0048864 69 0.701
nuclear division GO:0000280 128 0.644
Fly
mitotic cell cycle GO:0000278 326 0.643
dna dependent dna replication GO:0006261 44 0.617
positive regulation of mitotic cell cycle GO:0045931 60 0.571
negative regulation of dna metabolic process GO:0051053 57 0.570
vesicle mediated transport GO:0016192 371 0.564
double strand break repair GO:0006302 101 0.550
organelle fission GO:0048285 149 0.538
Fly
mitotic nuclear division GO:0007067 119 0.520
positive regulation of cellular component organization GO:0051130 376 0.496
mitotic cell cycle process GO:1903047 286 0.469
regulation of dna replication GO:0006275 68 0.441
regulation of chromatin modification GO:1903308 51 0.418
regulation of cell cycle GO:0051726 393 0.357
reproductive process GO:0022414 106 0.342
Worm
response to biotic stimulus GO:0009607 276 0.298
histone modification GO:0016570 251 0.251
regulation of cellular amino acid metabolic process GO:0006521 6 0.242
regulation of cell cycle process GO:0010564 266 0.237
dna repair GO:0006281 198 0.222
protein methylation GO:0006479 74 0.216
negative regulation of dna dependent dna replication GO:2000104 9 0.198
cellular response to dna damage stimulus GO:0006974 379 0.195
cell division GO:0051301 168 0.191
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.185
negative regulation of cell differentiation GO:0045596 171 0.183
metaphase anaphase transition of cell cycle GO:0044784 21 0.166
single organism reproductive process GO:0044702 98 0.165
endocytosis GO:0006897 159 0.151
embryo development GO:0009790 123 0.140
Worm
peptidyl lysine modification GO:0018205 144 0.136
cellular ketone metabolic process GO:0042180 80 0.134
regulation of dna dependent dna replication GO:0090329 19 0.129
negative regulation of developmental process GO:0051093 247 0.125
female gamete generation GO:0007292 2 0.123
reproduction GO:0000003 63 0.119
Worm Fly
reproductive structure development GO:0048608 55 0.116
cytokinesis GO:0000910 96 0.114
meiotic nuclear division GO:0007126 10 0.112
Fly
receptor mediated endocytosis GO:0006898 84 0.108
internal protein amino acid acetylation GO:0006475 101 0.104
negative regulation of cell cycle process GO:0010948 121 0.103
chromosome separation GO:0051304 23 0.103
ribonucleoprotein complex subunit organization GO:0071826 81 0.100
cell cycle dna replication GO:0044786 11 0.098
regulation of meiotic cell cycle GO:0051445 4 0.093
ubiquitin dependent protein catabolic process GO:0006511 206 0.089
amine metabolic process GO:0009308 44 0.086
tube development GO:0035295 125 0.082
embryo development ending in birth or egg hatching GO:0009792 34 0.082
Worm
ribonucleoprotein complex assembly GO:0022618 78 0.078
regulation of anatomical structure morphogenesis GO:0022603 286 0.072
rna interference GO:0016246 4 0.071
mitotic cell cycle phase transition GO:0044772 162 0.069
peptidyl lysine acetylation GO:0018394 101 0.069
regulation of cellular ketone metabolic process GO:0010565 50 0.069
g1 s transition of mitotic cell cycle GO:0000082 78 0.064
protein catabolic process GO:0030163 325 0.062
negative regulation of cell proliferation GO:0008285 228 0.060
regulation of nucleocytoplasmic transport GO:0046822 98 0.060
positive regulation of immune response GO:0050778 159 0.059
negative regulation of protein processing GO:0010955 142 0.058
cell development GO:0048468 328 0.057
modification dependent macromolecule catabolic process GO:0043632 212 0.057
regulation of protein complex assembly GO:0043254 147 0.057
single organism cellular localization GO:1902580 332 0.056
organelle localization GO:0051640 84 0.056
covalent chromatin modification GO:0016569 254 0.056
cytoplasmic transport GO:0016482 379 0.056
sex differentiation GO:0007548 45 0.055
gonad development GO:0008406 34 0.054
reproductive system development GO:0061458 56 0.053
signal transduction by phosphorylation GO:0023014 297 0.053
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.052
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.051
enzyme linked receptor protein signaling pathway GO:0007167 303 0.049
microtubule cytoskeleton organization GO:0000226 176 0.049
mitotic sister chromatid separation GO:0051306 18 0.047
organelle assembly GO:0070925 176 0.047
stem cell division GO:0017145 2 0.046
spermatid development GO:0007286 4 0.046
developmental process involved in reproduction GO:0003006 66 0.046
neuromuscular junction development GO:0007528 3 0.045
cellular macromolecular complex assembly GO:0034622 324 0.045
regulation of cell differentiation GO:0045595 393 0.044
response to other organism GO:0051707 261 0.044
nuclear transport GO:0051169 179 0.044
regulation of chromatin organization GO:1902275 56 0.044
chromosome condensation GO:0030261 15 0.043
protein acetylation GO:0006473 116 0.043
oogenesis GO:0048477 2 0.042
spindle organization GO:0007051 53 0.041
meiotic cell cycle process GO:1903046 8 0.041
Fly
modification dependent protein catabolic process GO:0019941 209 0.041
small gtpase mediated signal transduction GO:0007264 78 0.040
regulation of proteasomal protein catabolic process GO:0061136 87 0.040
skeletal system development GO:0001501 79 0.040
anatomical structure formation involved in morphogenesis GO:0048646 284 0.039
mrna metabolic process GO:0016071 175 0.039
regulation of protein processing GO:0070613 150 0.039
cellular component morphogenesis GO:0032989 314 0.038
protein localization to chromosome GO:0034502 30 0.038
regulation of histone modification GO:0031056 47 0.037
nucleoside catabolic process GO:0009164 408 0.037
cellular amino acid metabolic process GO:0006520 116 0.036
centrosome organization GO:0051297 58 0.036
tube morphogenesis GO:0035239 95 0.035
negative regulation of protein maturation GO:1903318 142 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
protein alkylation GO:0008213 74 0.035
positive regulation of growth GO:0045927 58 0.034
ribonucleoprotein complex biogenesis GO:0022613 116 0.034
chordate embryonic development GO:0043009 34 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.033
determination of adult lifespan GO:0008340 2 0.033
regulation of developmental growth GO:0048638 30 0.033
internal peptidyl lysine acetylation GO:0018393 97 0.033
innate immune response GO:0045087 178 0.033
microtubule based process GO:0007017 210 0.033
cell activation GO:0001775 213 0.033
positive regulation of protein phosphorylation GO:0001934 313 0.032
purine ribonucleoside metabolic process GO:0046128 437 0.032
microtubule organizing center organization GO:0031023 62 0.032
neural tube formation GO:0001841 3 0.032
oocyte development GO:0048599 1 0.031
nucleotide catabolic process GO:0009166 408 0.031
cellular protein catabolic process GO:0044257 261 0.031
cytokinesis completion of separation GO:0007109 3 0.030
positive regulation of organelle organization GO:0010638 195 0.030
regulation of mitosis GO:0007088 63 0.029
segmentation GO:0035282 4 0.029
development of primary sexual characteristics GO:0045137 35 0.029
regulation of protein import into nucleus GO:0042306 78 0.029
cell morphogenesis GO:0000902 296 0.029
somitogenesis GO:0001756 2 0.029
regulation of chromosome organization GO:0033044 103 0.028
methylation GO:0032259 106 0.028
atp metabolic process GO:0046034 176 0.028
regulation of intracellular transport GO:0032386 195 0.027
lymphocyte activation GO:0046649 133 0.027
dna endoreduplication GO:0042023 5 0.027
epithelium development GO:0060429 227 0.026
regulation of cellular amine metabolic process GO:0033238 11 0.026
protein ubiquitination GO:0016567 314 0.026
regulation of gene expression epigenetic GO:0040029 73 0.026
regulation of cellular component biogenesis GO:0044087 281 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.024
ribonucleoside triphosphate metabolic process GO:0009199 412 0.024
regulation of cellular response to stress GO:0080135 244 0.023
circulatory system development GO:0072359 262 0.023
cellular amine metabolic process GO:0044106 41 0.023
mapk cascade GO:0000165 288 0.023
protein acylation GO:0043543 138 0.023
regulation of growth GO:0040008 165 0.023
purine nucleoside triphosphate catabolic process GO:0009146 392 0.022
response to external biotic stimulus GO:0043207 261 0.022
response to ionizing radiation GO:0010212 65 0.022
lipid metabolic process GO:0006629 381 0.022
dna templated transcription initiation GO:0006352 35 0.022
cell cycle g1 s phase transition GO:0044843 80 0.022
regulation of mitotic sister chromatid separation GO:0010965 27 0.021
nucleoside triphosphate catabolic process GO:0009143 394 0.021
negative regulation of cellular component organization GO:0051129 235 0.021
regulation of multicellular organism growth GO:0040014 8 0.021
multicellular organismal aging GO:0010259 3 0.021
regulation of canonical wnt signaling pathway GO:0060828 88 0.020
histone lysine methylation GO:0034968 50 0.020
rna 3 end processing GO:0031123 35 0.020
nucleoside monophosphate metabolic process GO:0009123 191 0.020
histone acetylation GO:0016573 93 0.020
regulation of dna repair GO:0006282 47 0.020
regulation of immune response GO:0050776 201 0.020
growth GO:0040007 202 0.019
cytokinetic process GO:0032506 12 0.019
dephosphorylation GO:0016311 209 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.019
protein modification by small protein conjugation GO:0032446 342 0.019
establishment of protein localization to organelle GO:0072594 172 0.019
negative regulation of protein metabolic process GO:0051248 391 0.019
cellular macromolecule catabolic process GO:0044265 380 0.019
neuroblast proliferation GO:0007405 4 0.018
positive regulation of immune system process GO:0002684 283 0.018
morphogenesis of an epithelium GO:0002009 60 0.018
chromatin modification GO:0016568 298 0.018
dna conformation change GO:0071103 113 0.018
lung alveolus development GO:0048286 4 0.018
regulation of protein ubiquitination GO:0031396 95 0.017
regulation of cell activation GO:0050865 125 0.017
glycerolipid metabolic process GO:0046486 107 0.017
organ morphogenesis GO:0009887 147 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.017
central nervous system development GO:0007417 123 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
purine ribonucleoside catabolic process GO:0046130 398 0.017
regulation of meiosis GO:0040020 3 0.017
metaphase anaphase transition of mitotic cell cycle GO:0007091 21 0.017
blastocyst development GO:0001824 3 0.016
protein localization to organelle GO:0033365 280 0.016
positive regulation of catabolic process GO:0009896 310 0.016
nucleosome organization GO:0034728 66 0.016
negative regulation of proteolysis GO:0045861 132 0.016
ribonucleoside triphosphate catabolic process GO:0009203 391 0.016
immune effector process GO:0002252 159 0.016
regulation of cell division GO:0051302 116 0.016
generation of neurons GO:0048699 152 0.015
purine nucleoside triphosphate metabolic process GO:0009144 412 0.015
lipid biosynthetic process GO:0008610 177 0.015
protein localization to chromatin GO:0071168 11 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
negative regulation of cell cycle GO:0045786 193 0.015
pattern specification process GO:0007389 43 0.015
secretory granule organization GO:0033363 2 0.015
gene silencing GO:0016458 49 0.014
heart morphogenesis GO:0003007 48 0.014
regulation of protein stability GO:0031647 87 0.014
purine nucleoside catabolic process GO:0006152 398 0.014
regulation of nuclear division GO:0051783 65 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
ncrna metabolic process GO:0034660 108 0.014
protein targeting to nucleus GO:0044744 104 0.014
purine containing compound catabolic process GO:0072523 411 0.014
regulation of protein targeting GO:1903533 91 0.014
positive regulation of dna metabolic process GO:0051054 73 0.013
negative regulation of multicellular organismal process GO:0051241 317 0.013
response to abiotic stimulus GO:0009628 336 0.013
oocyte differentiation GO:0009994 2 0.013
cell growth GO:0016049 160 0.013
developmental growth GO:0048589 48 0.013
regulation of protein localization GO:0032880 296 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
regulation of transcription initiation from rna polymerase ii promoter GO:0060260 8 0.013
positive regulation of phosphorylation GO:0042327 394 0.013
regulation of dna templated transcription initiation GO:2000142 9 0.013
neuron development GO:0048666 113 0.013
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.013
cognition GO:0050890 43 0.013
negative regulation of peptidase activity GO:0010466 91 0.012
carbohydrate metabolic process GO:0005975 207 0.012
negative regulation of cellular protein metabolic process GO:0032269 353 0.012
cellular protein complex assembly GO:0043623 188 0.012
regulation of small gtpase mediated signal transduction GO:0051056 156 0.012
positive regulation of cellular amine metabolic process GO:0033240 7 0.012
regulation of histone acetylation GO:0035065 19 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
macromolecule methylation GO:0043414 97 0.012
regulation of protein maturation GO:1903317 150 0.012
negative regulation of catabolic process GO:0009895 104 0.012
nucleoside triphosphate metabolic process GO:0009141 422 0.012
protein targeting GO:0006605 187 0.011
positive regulation of developmental process GO:0051094 314 0.011
response to radiation GO:0009314 151 0.011
glycosyl compound catabolic process GO:1901658 413 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
regulation of protein transport GO:0051223 213 0.011
regulation of response to dna damage stimulus GO:2001020 94 0.011
intracellular protein transport GO:0006886 270 0.011
cell part morphogenesis GO:0032990 137 0.011
cellular amide metabolic process GO:0043603 69 0.011
recombinational repair GO:0000725 50 0.011
regulation of mitotic spindle checkpoint GO:1903504 8 0.011
positive regulation of multicellular organism growth GO:0040018 6 0.010
regulation of cell morphogenesis GO:0022604 153 0.010
protein maturation GO:0051604 233 0.010
regulation of mapk cascade GO:0043408 262 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.010
posttranscriptional regulation of gene expression GO:0010608 213 0.010
mrna processing GO:0006397 133 0.010
positive regulation of cellular component biogenesis GO:0044089 158 0.010
defense response to bacterium GO:0042742 63 0.010

WAPAL disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.036
disease of cellular proliferation DOID:14566 174 0.036
organ system cancer DOID:0050686 164 0.036