|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
1.000
|
Yeast Fly |
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
1.000
|
Yeast Fly |
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
1.000
|
Yeast Fly |
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
1.000
|
Yeast Fly |
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
1.000
|
Yeast Mouse Fly |
|
|
actin filament polymerization
|
GO:0030041 |
45 |
1.000
|
Yeast Mouse Fly |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
1.000
|
Yeast Fly |
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
1.000
|
Yeast Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
1.000
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
1.000
|
Yeast Mouse Fly |
|
|
regulation of actin nucleation
|
GO:0051125 |
10 |
0.999
|
Yeast |
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.999
|
Yeast Fly |
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.999
|
Yeast Fly |
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.999
|
Yeast Fly |
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.999
|
Yeast Fly |
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.999
|
Yeast Fly |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.999
|
Yeast Fly |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.999
|
Yeast Mouse Fly |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.998
|
Yeast Mouse Fly |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.998
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.998
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.998
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.998
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.997
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.997
|
|
|
|
arp2 3 complex mediated actin nucleation
|
GO:0034314 |
17 |
0.996
|
Yeast Fly |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.996
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.996
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.995
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.995
|
Yeast Fly |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.995
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.994
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.993
|
Yeast Fly |
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.993
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.992
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.992
|
Yeast Mouse Fly |
|
|
protein polymerization
|
GO:0051258 |
71 |
0.991
|
Yeast Mouse Fly |
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.990
|
Yeast Fly |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.990
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.989
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.989
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.988
|
|
|
|
regulation of arp2 3 complex mediated actin nucleation
|
GO:0034315 |
6 |
0.987
|
Yeast |
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.987
|
Yeast |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.987
|
Fly |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.986
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.985
|
Mouse |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.985
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.984
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.984
|
Fly |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.983
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.981
|
Fly |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.977
|
Yeast Fly |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.976
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.975
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.973
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.972
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.972
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.960
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.960
|
Fly |
|
|
t cell activation
|
GO:0042110 |
99 |
0.959
|
Mouse |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.957
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.957
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.956
|
|
|
|
mast cell degranulation
|
GO:0043303 |
4 |
0.956
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.954
|
Yeast Fly |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.949
|
Fly |
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.947
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.947
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.946
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.944
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.943
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.943
|
Fly |
|
|
mast cell activation involved in immune response
|
GO:0002279 |
4 |
0.943
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.934
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.932
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.931
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.931
|
Yeast Fly |
|
|
nervous system development
|
GO:0007399 |
293 |
0.929
|
Fly |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.928
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.927
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.923
|
|
|
|
positive regulation of actin nucleation
|
GO:0051127 |
6 |
0.922
|
Yeast |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.920
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.919
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.910
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.909
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.903
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.897
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.892
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.892
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.892
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.890
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.890
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.889
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.885
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.885
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.881
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.879
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.869
|
Fly |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.859
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.856
|
|
|
|
memory
|
GO:0007613 |
3 |
0.856
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.856
|
Fly |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.850
|
Fly |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.849
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.848
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.845
|
|
|
|
actin nucleation
|
GO:0045010 |
21 |
0.845
|
Yeast Fly |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.843
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.839
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.834
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.834
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.833
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.832
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.829
|
Fly |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.822
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.822
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.818
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.815
|
Yeast |
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.810
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.809
|
Fly |
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.805
|
|
|
|
negative regulation of anoikis
|
GO:2000811 |
15 |
0.803
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.801
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.801
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.794
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.794
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.791
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.787
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.785
|
Yeast Mouse Fly |
|
|
response to other organism
|
GO:0051707 |
261 |
0.778
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.775
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.774
|
Fly |
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.766
|
Yeast |
|
|
cell junction organization
|
GO:0034330 |
79 |
0.764
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.758
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.749
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.749
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.735
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.735
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.728
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.724
|
Fly |
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.721
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.716
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.713
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.708
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.699
|
|
|
|
regulation of platelet aggregation
|
GO:0090330 |
4 |
0.698
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.685
|
Fly |
|
|
immune system development
|
GO:0002520 |
195 |
0.684
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.668
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.666
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.665
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.665
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.660
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.659
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.658
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.657
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.648
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.647
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.646
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.644
|
Mouse Fly |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.637
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.632
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.626
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.620
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.618
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.615
|
Fly |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.612
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.606
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.606
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.605
|
|
|
|
regulation of anoikis
|
GO:2000209 |
19 |
0.596
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.592
|
Mouse |
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.590
|
|
|
|
regulation of caveolin mediated endocytosis
|
GO:2001286 |
2 |
0.589
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.588
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.585
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.583
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.582
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.581
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.580
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.579
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.573
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.571
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.566
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.559
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.557
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.555
|
|
|
|
early endosome to late endosome transport
|
GO:0045022 |
21 |
0.554
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.537
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.534
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.533
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.528
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.527
|
Fly |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.526
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.519
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.519
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.518
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.514
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.511
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.505
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.505
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.504
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.501
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.498
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.497
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.497
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.491
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.491
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
7 |
0.490
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.488
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.488
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.484
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
5 |
0.482
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.482
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.480
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.478
|
|
|
|
activation of janus kinase activity
|
GO:0042976 |
7 |
0.478
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
35 |
0.474
|
|
|
|
neuroblast division
|
GO:0055057 |
1 |
0.472
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.469
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.467
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.467
|
|
|
|
regulation of natural killer cell proliferation
|
GO:0032817 |
4 |
0.466
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
3 |
0.464
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.454
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.449
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.448
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.444
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.442
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.438
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.434
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.432
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.431
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.428
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.428
|
Fly |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.428
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.422
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.421
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.420
|
|
|
|
learning
|
GO:0007612 |
11 |
0.420
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.416
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.414
|
Fly |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.413
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.412
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.411
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.410
|
|
|
|
integrin mediated signaling pathway
|
GO:0007229 |
32 |
0.409
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.407
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.404
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.399
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.398
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.397
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.396
|
Fly |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.395
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.394
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.393
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.393
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.389
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.387
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
3 |
0.385
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.384
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.383
|
Fly |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.383
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.378
|
Human |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.377
|
|
|
|
negative regulation of protein homooligomerization
|
GO:0032463 |
4 |
0.374
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.372
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.370
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
34 |
0.369
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.368
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.366
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.365
|
|
|
|
positive regulation of mast cell activation
|
GO:0033005 |
2 |
0.364
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.363
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.362
|
Mouse |
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.362
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.361
|
|
|
|
regulation of phosphatidylinositol 3 kinase activity
|
GO:0043551 |
14 |
0.361
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.357
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.357
|
Fly |
|
|
plasma membrane raft assembly
|
GO:0044854 |
4 |
0.353
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.352
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.351
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.349
|
|
|
|
negative regulation of mitochondrial depolarization
|
GO:0051902 |
2 |
0.346
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.346
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.344
|
Fly |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.340
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.338
|
|
|
|
negative regulation of protein oligomerization
|
GO:0032460 |
8 |
0.335
|
|
|
|
positive regulation of leukocyte degranulation
|
GO:0043302 |
3 |
0.333
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.331
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.330
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.328
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.325
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.324
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
13 |
0.319
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.317
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.315
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.310
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.310
|
|
|
|
response to retinoic acid
|
GO:0032526 |
33 |
0.310
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.308
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
35 |
0.307
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.306
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.299
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.297
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.296
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.295
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.289
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.288
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.283
|
|
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.283
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.282
|
|
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.281
|
Yeast |
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.276
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.274
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.273
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.268
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.268
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.268
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.268
|
Fly |
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.267
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.267
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.264
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.260
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.260
|
|
|
|
synapse assembly
|
GO:0007416 |
8 |
0.259
|
Fly |
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.258
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.257
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.256
|
|
|
|
membrane depolarization
|
GO:0051899 |
26 |
0.253
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.253
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.248
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.247
|
Fly |
|
|
negative regulation of t cell receptor signaling pathway
|
GO:0050860 |
4 |
0.247
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.245
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.244
|
Fly |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.241
|
|
|
|
system process
|
GO:0003008 |
349 |
0.239
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.239
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.238
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.235
|
Human Fly |
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
46 |
0.231
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
13 |
0.231
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
26 |
0.228
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.228
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.227
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.225
|
Fly |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.221
|
|
|
|
regulation of mitochondrial membrane potential
|
GO:0051881 |
23 |
0.219
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.219
|
|
|
|
lamellipodium organization
|
GO:0097581 |
30 |
0.218
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
36 |
0.217
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.216
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.213
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.211
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.209
|
Fly |
|
|
regulation of actin cytoskeleton reorganization
|
GO:2000249 |
12 |
0.209
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.208
|
|
|
|
positive regulation of actin cytoskeleton reorganization
|
GO:2000251 |
9 |
0.205
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.205
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.205
|
|
|
|
transition metal ion homeostasis
|
GO:0055076 |
31 |
0.203
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.202
|
|
|
|
mast cell activation
|
GO:0045576 |
6 |
0.201
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.201
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.200
|
|
|
|
mast cell mediated immunity
|
GO:0002448 |
5 |
0.198
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.197
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
13 |
0.196
|
|
|
|
lamellipodium assembly
|
GO:0030032 |
26 |
0.196
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.194
|
Fly |
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.193
|
|
|
|
heterotypic cell cell adhesion
|
GO:0034113 |
28 |
0.192
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.190
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.189
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.187
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.186
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
37 |
0.186
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.186
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.185
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.184
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.183
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.182
|
|
|
|
b cell receptor signaling pathway
|
GO:0050853 |
18 |
0.178
|
|
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
20 |
0.177
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.175
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.175
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.174
|
|
|
|
azole transport
|
GO:0045117 |
4 |
0.174
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.173
|
|
|
|
positive regulation of cytokine mediated signaling pathway
|
GO:0001961 |
12 |
0.173
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.172
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.170
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.170
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.170
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.168
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase activity
|
GO:0043552 |
12 |
0.167
|
|
|
|
positive regulation of mononuclear cell proliferation
|
GO:0032946 |
47 |
0.167
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.166
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
44 |
0.164
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.164
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
24 |
0.163
|
|
|
|
regulation of protein oligomerization
|
GO:0032459 |
26 |
0.161
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.158
|
|
|
|
interferon gamma mediated signaling pathway
|
GO:0060333 |
7 |
0.157
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.157
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.157
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.157
|
|
|
|
natural killer cell proliferation
|
GO:0001787 |
4 |
0.157
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.156
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.155
|
Fly |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.153
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.151
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.148
|
Fly |
|
|
stem cell division
|
GO:0017145 |
2 |
0.147
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.147
|
|
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.146
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
4 |
0.146
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.145
|
Fly |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.144
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.143
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.142
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.142
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.141
|
Fly |
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.141
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.141
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.137
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.136
|
|
|
|
positive regulation of response to interferon gamma
|
GO:0060332 |
2 |
0.136
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.135
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.135
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.134
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.134
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.134
|
|
|
|
growth
|
GO:0040007 |
202 |
0.132
|
Fly |
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.132
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.131
|
Mouse |
|
|
cellular transition metal ion homeostasis
|
GO:0046916 |
21 |
0.131
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.131
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.130
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.129
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.129
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.129
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.129
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.128
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.127
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.127
|
|
|
|
regulation of cell adhesion mediated by integrin
|
GO:0033628 |
22 |
0.123
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.122
|
|
|
|
rac protein signal transduction
|
GO:0016601 |
12 |
0.122
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.120
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.119
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
30 |
0.117
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
10 |
0.116
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.116
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.116
|
|
|
|
positive regulation of leukocyte migration
|
GO:0002687 |
46 |
0.114
|
|
|
|
positive regulation of cell substrate adhesion
|
GO:0010811 |
37 |
0.114
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.111
|
|
|
|
filopodium assembly
|
GO:0046847 |
18 |
0.111
|
|
|
|
head development
|
GO:0060322 |
108 |
0.110
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
33 |
0.110
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.110
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.109
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.109
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.108
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.107
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.106
|
|
|
|
regulation of membrane depolarization
|
GO:0003254 |
19 |
0.106
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.105
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.105
|
Human |
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.105
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.104
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.103
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.102
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.102
|
|
|
|
platelet degranulation
|
GO:0002576 |
2 |
0.102
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.101
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
25 |
0.101
|
|
|
|
visual learning
|
GO:0008542 |
1 |
0.100
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.100
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.099
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.099
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.098
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.098
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.097
|
|
|
|
insulin secretion
|
GO:0030073 |
39 |
0.096
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.096
|
|
|
|
response to heat
|
GO:0009408 |
21 |
0.096
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.094
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.094
|
|
