|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.964
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.963
|
|
|
|
cell competition in a multicellular organism
|
GO:0035212 |
1 |
0.959
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.936
|
|
|
|
positive regulation of arp2 3 complex mediated actin nucleation
|
GO:2000601 |
5 |
0.932
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.929
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.917
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.910
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.902
|
Yeast Rat |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.898
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.855
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.846
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.841
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.829
|
|
|
|
positive regulation of actin nucleation
|
GO:0051127 |
6 |
0.826
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.813
|
|
|
|
cuticle development
|
GO:0042335 |
1 |
0.808
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.806
|
Yeast Mouse Rat |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.805
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.804
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.793
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.780
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.761
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.740
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.735
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.733
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.732
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.726
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.724
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.719
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.716
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.714
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.706
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.700
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.699
|
Rat |
|
|
regulation of arp2 3 complex mediated actin nucleation
|
GO:0034315 |
6 |
0.693
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.679
|
|
|
|
arp2 3 complex mediated actin nucleation
|
GO:0034314 |
17 |
0.675
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.660
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.647
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.643
|
Yeast |
|
|
regulation of actin nucleation
|
GO:0051125 |
10 |
0.642
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.635
|
Mouse |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.623
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.620
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.612
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.610
|
Rat |
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.602
|
Rat |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.592
|
Rat |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.577
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.576
|
Mouse |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.565
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.562
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.559
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.556
|
Rat |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.554
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.551
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.531
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.516
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.513
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.513
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.506
|
|
|
|
early endosome to late endosome transport
|
GO:0045022 |
21 |
0.500
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.498
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.492
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.491
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.474
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.464
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.462
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.461
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.457
|
|
|
|
memory
|
GO:0007613 |
3 |
0.449
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.446
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.443
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.435
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.431
|
|
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.427
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.424
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.423
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.422
|
Rat |
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.420
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.417
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.416
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.415
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.412
|
|
|
|
myoblast fusion
|
GO:0007520 |
1 |
0.398
|
|
|
|
growth
|
GO:0040007 |
202 |
0.397
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.397
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.395
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.394
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.391
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.383
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.380
|
Mouse |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.373
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.360
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.359
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.359
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.358
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.353
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.351
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.349
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.340
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.339
|
Rat |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.335
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.334
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.331
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.329
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.318
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.317
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.316
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.313
|
|
|
|
positive regulation of metalloenzyme activity
|
GO:0048554 |
2 |
0.311
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.307
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.302
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.299
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.298
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.298
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.297
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.296
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.294
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.287
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.287
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.285
|
Yeast |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.284
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.282
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.274
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.274
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.274
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.269
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.262
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.261
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.259
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.258
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.255
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.254
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.253
|
|
|
|
positive regulation of synapse structural plasticity
|
GO:0051835 |
2 |
0.251
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.249
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.246
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.243
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.242
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.240
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.239
|
|
|
|
regulation of protein oligomerization
|
GO:0032459 |
26 |
0.237
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.229
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.225
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.224
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.220
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.218
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.216
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.214
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.213
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.213
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.212
|
Rat |
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.211
|
|
|
|
membrane budding
|
GO:0006900 |
28 |
0.211
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.211
|
|
|
|
actin nucleation
|
GO:0045010 |
21 |
0.207
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.206
|
|
|
|
negative regulation of developmental growth
|
GO:0048640 |
10 |
0.206
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.205
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.205
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.204
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.200
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.199
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.197
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.195
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.194
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.192
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.191
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.190
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.189
|
Rat |
|
|
female gamete generation
|
GO:0007292 |
2 |
0.189
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.188
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.188
|
Rat |
|
|
tissue migration
|
GO:0090130 |
119 |
0.187
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.185
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.185
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.182
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.182
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.180
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.180
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.180
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.178
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.178
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.175
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.175
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.171
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.171
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.166
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.166
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.164
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.164
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.162
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.159
|
Rat |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.158
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.157
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.156
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.156
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.155
|
Yeast |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.153
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.153
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.153
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.153
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.152
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.151
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.151
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.151
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.149
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.147
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.147
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.147
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.146
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.144
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.144
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.143
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.139
|
Mouse |
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.139
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.136
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.135
|
|
|
|
regulation of synapse assembly
|
GO:0051963 |
5 |
0.134
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.134
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.129
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.128
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.127
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.127
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.126
|
|
|
|
negative regulation of protein complex assembly
|
GO:0031333 |
43 |
0.126
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.126
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.125
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.123
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.123
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.119
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.119
|
|
|
|
negative regulation of protein homooligomerization
|
GO:0032463 |
4 |
0.117
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.116
|
|
|
|
regulation of actin filament bundle assembly
|
GO:0032231 |
36 |
0.116
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.115
|
|
|
|
anoikis
|
GO:0043276 |
22 |
0.115
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
28 |
0.114
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.114
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.114
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.112
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.109
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.109
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.108
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.108
|
Rat |
|
|
axon development
|
GO:0061564 |
34 |
0.106
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.105
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.104
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.104
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.103
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.103
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.103
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.100
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.099
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.099
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.098
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.098
|
Yeast |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.097
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.096
|
Rat |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.096
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
57 |
0.096
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.095
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.095
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.094
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.093
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.093
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.092
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.091
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.091
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.091
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.091
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.090
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.090
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.088
|
|
|
|
dendritic spine maintenance
|
GO:0097062 |
1 |
0.088
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.087
|
|
|
|
caveolin mediated endocytosis
|
GO:0072584 |
4 |
0.086
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.083
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.083
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.083
|
|
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.082
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.082
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.081
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.081
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.081
|
|
|
|
epithelial cell morphogenesis
|
GO:0003382 |
8 |
0.081
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
24 |
0.080
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.080
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.080
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.080
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.079
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.079
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.078
|
|
|
|
regulation of granulocyte differentiation
|
GO:0030852 |
11 |
0.077
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.076
|
|
|
|
clathrin mediated endocytosis
|
GO:0072583 |
8 |
0.076
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.076
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
39 |
0.075
|
|
|
|
keratinization
|
GO:0031424 |
2 |
0.075
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.073
|
|
|
|
negative regulation of mitochondrial depolarization
|
GO:0051902 |
2 |
0.073
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.072
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.072
|
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.071
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.071
|
|
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
25 |
0.071
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.070
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.070
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.069
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.069
|
|
|
|
regulation of clathrin mediated endocytosis
|
GO:2000369 |
4 |
0.069
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.069
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.069
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.068
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.067
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.067
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.066
|
Yeast |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.066
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.066
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.066
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.066
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.065
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.065
|
Yeast |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.065
|
|
|
|
mast cell degranulation
|
GO:0043303 |
4 |
0.064
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.064
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.063
|
|
|
|
regulation of mitochondrial membrane potential
|
GO:0051881 |
23 |
0.063
|
|
|
|
activation of ras gtpase activity
|
GO:0032856 |
15 |
0.062
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.062
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.061
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.061
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.061
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.061
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.060
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
16 |
0.060
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
54 |
0.060
|
|
|
|
regulation of membrane tubulation
|
GO:1903525 |
2 |
0.060
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.059
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.059
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.058
|
|
|
|
positive regulation of hormone secretion
|
GO:0046887 |
25 |
0.058
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.058
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.058
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.058
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.057
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.057
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.057
|
|
|
|
positive regulation of clathrin mediated endocytosis
|
GO:2000370 |
2 |
0.057
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.056
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.056
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.056
|
|
|
|
positive regulation of interferon gamma mediated signaling pathway
|
GO:0060335 |
2 |
0.055
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.055
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.055
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.054
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.054
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.052
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.052
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.051
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.051
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.051
|
|
|
|
positive regulation of intrinsic apoptotic signaling pathway
|
GO:2001244 |
28 |
0.051
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.051
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.051
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
31 |
0.051
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.051
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.050
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.050
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.050
|
|
|
|
somatic stem cell division
|
GO:0048103 |
1 |
0.050
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.050
|
|
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
20 |
0.050
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.050
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.050
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.049
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.049
|
|
|
|
head development
|
GO:0060322 |
108 |
0.049
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.048
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
0.048
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.048
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.048
|
|
|
|
vesicle transport along actin filament
|
GO:0030050 |
2 |
0.048
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.048
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.048
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.047
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.047
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.047
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.047
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.047
|
|
|
|
regulation of leukocyte migration
|
GO:0002685 |
63 |
0.047
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.046
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.046
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.046
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.046
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.046
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.045
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
34 |
0.044
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.044
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.044
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.044
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.043
|
|
|
|
gland morphogenesis
|
GO:0022612 |
8 |
0.043
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.043
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.043
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.043
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.042
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.042
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.042
|
Rat |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.041
|
Yeast |
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.041
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.041
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.041
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.041
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.041
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.040
|
|
|
|
microtubule bundle formation
|
GO:0001578 |
15 |
0.039
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.039
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.039
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.039
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.039
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.039
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.038
|
|
|
|
regulation of synapse structural plasticity
|
GO:0051823 |
2 |
0.038
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.038
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.038
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.038
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.038
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.038
|
|
|
|
positive regulation of cell matrix adhesion
|
GO:0001954 |
23 |
0.038
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.038
|
|
|
|
interferon gamma production
|
GO:0032609 |
39 |
0.038
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.038
|
Yeast |
|
|
defense response
|
GO:0006952 |
315 |
0.038
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.037
|
|
|
|
establishment of neuroblast polarity
|
GO:0045200 |
1 |
0.036
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.036
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.036
|
Yeast |
|
|
lymphocyte aggregation
|
GO:0071593 |
1 |
0.035
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.035
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.035
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.035
|
|
|
|
myotube differentiation
|
GO:0014902 |
22 |
0.035
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
24 |
0.035
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.035
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
44 |
0.035
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
50 |
0.035
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.034
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.034
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.034
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.034
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.034
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.034
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.034
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.034
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.033
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.033
|
|
|
|
regulation of cell adhesion mediated by integrin
|
GO:0033628 |
22 |
0.033
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.033
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.033
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.033
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.033
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.032
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
26 |
0.032
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
37 |
0.032
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.032
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.031
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.031
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.031
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.031
|
|
|
|
negative regulation of protein oligomerization
|
GO:0032460 |
8 |
0.031
|
|
|
|
transition metal ion homeostasis
|
GO:0055076 |
31 |
0.031
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.031
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.031
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.031
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.030
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.030
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.030
|
|
|
|
axon guidance
|
GO:0007411 |
12 |
0.030
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.030
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.030
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.030
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.030
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.030
|
|
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.030
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.030
|
|
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.030
|
|
|
|
regulation of synapse organization
|
GO:0050807 |
7 |
0.029
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.029
|
|
