|
|
canonical wnt signaling pathway involved in mesenchymal stem cell differentiation
|
GO:0044338 |
2 |
0.965
|
|
|
|
wnt signaling pathway calcium modulating pathway
|
GO:0007223 |
2 |
0.951
|
|
|
|
positive regulation of epithelial cell proliferation involved in wound healing
|
GO:0060054 |
3 |
0.933
|
|
|
|
canonical wnt signaling pathway involved in osteoblast differentiation
|
GO:0044339 |
2 |
0.919
|
|
|
|
regulation of sodium dependent phosphate transport
|
GO:2000118 |
2 |
0.882
|
|
|
|
spemann organizer formation
|
GO:0060061 |
1 |
0.701
|
|
|
|
non canonical wnt signaling pathway via mapk cascade
|
GO:0038030 |
4 |
0.699
|
Mouse |
|
|
negative regulation of ectodermal cell fate specification
|
GO:0042666 |
1 |
0.487
|
|
|
|
negative regulation of ectoderm development
|
GO:2000384 |
1 |
0.434
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.402
|
|
|
|
retina vasculature morphogenesis in camera type eye
|
GO:0061299 |
3 |
0.389
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.383
|
Human Mouse Rat Worm |
|
|
negative regulation of sodium dependent phosphate transport
|
GO:2000119 |
1 |
0.382
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.332
|
Human Zebrafish Mouse |
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.324
|
Rat |
|
|
negative regulation of cell fate specification
|
GO:0009996 |
3 |
0.316
|
Human |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.309
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.301
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.297
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.297
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.294
|
Human Mouse |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.290
|
Human Mouse Rat |
|
|
segmentation
|
GO:0035282 |
4 |
0.281
|
Mouse |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.280
|
|
|
|
negative regulation of cell fate commitment
|
GO:0010454 |
3 |
0.270
|
Human |
|
|
negative regulation of rho gtpase activity
|
GO:0034259 |
4 |
0.268
|
|
|
|
negative regulation of gastrulation
|
GO:2000542 |
4 |
0.264
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.263
|
Human |
|
|
regulation of ectodermal cell fate specification
|
GO:0042665 |
1 |
0.263
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.262
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.261
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.243
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.242
|
Human Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.238
|
|
|
|
regulation of phosphate transport
|
GO:0010966 |
3 |
0.229
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.227
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.222
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.220
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.218
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.216
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.215
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.213
|
|
|
|
retina vasculature development in camera type eye
|
GO:0061298 |
3 |
0.211
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.210
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.206
|
|
|
|
ectodermal cell fate specification
|
GO:0001715 |
1 |
0.195
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.193
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.192
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.192
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.190
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.187
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.186
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.184
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.184
|
Mouse |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.184
|
Mouse |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.183
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.182
|
Mouse Rat |
|
|
autocrine signaling
|
GO:0035425 |
2 |
0.179
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.176
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.176
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.176
|
Mouse |
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.175
|
Human |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.175
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.173
|
Human Zebrafish Mouse Rat |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.173
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.169
|
Human Mouse Rat |
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.166
|
Human |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.165
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.163
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.163
|
Human Zebrafish Mouse Rat |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.162
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.162
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.161
|
Human Zebrafish Mouse |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.161
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.161
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.160
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.158
|
Human Zebrafish Mouse |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.158
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.157
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.154
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.151
|
Human Mouse |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.150
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.145
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.143
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.142
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.142
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.141
|
Zebrafish |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.138
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.138
|
|
|
|
regulation of ectoderm development
|
GO:2000383 |
1 |
0.136
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.136
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.134
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.133
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.132
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.131
|
Mouse |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.130
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.128
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.127
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.125
|
Zebrafish Mouse Rat |
|
|
ectodermal cell fate commitment
|
GO:0001712 |
1 |
0.125
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.123
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.122
|
Human Mouse |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.122
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.122
|
Mouse |
|
|
neural tube formation
|
GO:0001841 |
3 |
0.120
|
Mouse |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.119
|
Human |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.118
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.117
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.117
|
Human Zebrafish Mouse |
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.116
|
Mouse |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.116
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.115
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.114
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.114
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.114
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.111
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.111
|
Worm |
|
|
hard palate development
|
GO:0060022 |
1 |
0.111
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.111
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.111
|
Mouse Rat |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.110
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.110
|
Human Zebrafish |
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.109
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.109
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.108
|
Human |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.108
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.107
|
Human |
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
0.105
|
Human Mouse |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.104
|
Human |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.103
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.102
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.102
|
Human Mouse |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.102
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.101
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.101
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.101
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.100
|
Human Mouse Rat Worm |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.100
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.100
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.099
|
Mouse |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.098
|
Human Mouse |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.098
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.098
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.098
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.096
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.095
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.095
|
|
|
|
system process
|
GO:0003008 |
349 |
0.094
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.094
|
Rat |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.093
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.093
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.093
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.092
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.091
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.091
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.091
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.091
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.090
|
Zebrafish |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.090
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.090
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.090
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.090
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.089
|
Mouse |
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.089
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.089
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.086
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.086
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.086
|
Rat |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.086
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.085
|
Rat |
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.084
|
Human Zebrafish Mouse |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.083
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.083
|
Mouse |
|
|
regulation of receptor internalization
|
GO:0002090 |
15 |
0.083
|
Human |
|
|
growth
|
GO:0040007 |
202 |
0.083
|
Zebrafish Mouse |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.083
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.082
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.081
|
|
|
|
ventricular septum morphogenesis
|
GO:0060412 |
3 |
0.081
|
Mouse |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.080
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.080
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.079
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.079
|
Human |
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.079
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.078
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.078
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.078
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.078
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.078
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.078
|
Mouse |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.077
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.077
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.076
|
Human |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.076
|
Human Mouse Rat |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.075
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.075
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.075
|
Human Mouse |
|
|
epidermal cell differentiation
|
GO:0009913 |
45 |
0.075
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.074
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.074
|
Human |
|
|
anion transport
|
GO:0006820 |
161 |
0.074
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.073
|
Human Mouse |
|
|
muscle structure development
|
GO:0061061 |
98 |
0.073
|
Human Mouse |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.073
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.073
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.072
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.072
|
Human Mouse |
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.072
|
Mouse Rat |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.071
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.070
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.070
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.070
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.070
|
Mouse Rat Worm |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.069
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.069
|
|
|
|
tube closure
|
GO:0060606 |
3 |
0.068
|
Mouse |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.068
|
|
|
|
ectoderm development
|
GO:0007398 |
3 |
0.067
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.067
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.066
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.066
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
14 |
0.065
|
|
|
|
regulation of gastrulation
|
GO:0010470 |
12 |
0.064
|
Human |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.064
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.063
|
Zebrafish |
|
|
cell growth
|
GO:0016049 |
160 |
0.063
|
Zebrafish Mouse |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.063
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.062
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.062
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.062
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.062
|
Mouse |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.061
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.061
|
Mouse |
|
|
heart development
|
GO:0007507 |
95 |
0.060
|
Human Mouse |
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.060
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.060
|
Mouse |
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
49 |
0.059
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.058
|
Human |
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.057
|
Human |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.057
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.057
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.057
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.057
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.056
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.056
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.055
|
Mouse |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.054
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.054
|
Human |
|
|
organ formation
|
GO:0048645 |
3 |
0.053
|
Mouse |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.053
|
|
|
|
negative regulation of cell substrate adhesion
|
GO:0010812 |
24 |
0.053
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.053
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.053
|
|
|
|
positive regulation of cgmp metabolic process
|
GO:0030825 |
5 |
0.052
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.052
|
Human |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.052
|
Human |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.052
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.051
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.050
|
Human Mouse |
|
|
positive regulation of receptor internalization
|
GO:0002092 |
12 |
0.050
|
Human |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.050
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.049
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.049
|
Human |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.048
|
Human Mouse Worm |
|
|
epidermis development
|
GO:0008544 |
59 |
0.048
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.048
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.048
|
Human Mouse Worm |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.048
|
Human |
|
|
oogenesis
|
GO:0048477 |
2 |
0.047
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.047
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.047
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.047
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.046
|
Human |
|
|
response to other organism
|
GO:0051707 |
261 |
0.046
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.046
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.045
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.045
|
Mouse |
|
|
angiogenesis
|
GO:0001525 |
147 |
0.045
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.045
|
Mouse |
|
|
nuclear import
|
GO:0051170 |
106 |
0.044
|
Human |
|
|
regulation of epidermis development
|
GO:0045682 |
19 |
0.044
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.044
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.043
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.043
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.043
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.043
|
Mouse |
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.043
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.043
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.042
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.042
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.042
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.041
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.041
|
Mouse |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.041
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.040
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.040
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.040
|
Mouse Rat Worm |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.040
|
Human Mouse |
|
|
kidney development
|
GO:0001822 |
53 |
0.040
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.040
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.039
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.039
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.039
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.039
|
Human Mouse |
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
26 |
0.039
|
Mouse |
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.039
|
Human |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.039
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.038
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.038
|
|
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.038
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.037
|
Mouse |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.037
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.037
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.037
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.037
|
Mouse Rat Worm |
|
|
protein targeting
|
GO:0006605 |
187 |
0.036
|
Human |
|
|
wound healing
|
GO:0042060 |
115 |
0.036
|
|
|
|
catenin import into nucleus
|
GO:0035411 |
18 |
0.036
|
Human |
|
|
negative regulation of nucleotide catabolic process
|
GO:0030812 |
16 |
0.036
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.035
|
Human Mouse |
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.035
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.035
|
Mouse |
|
|
central nervous system development
|
GO:0007417 |
123 |
0.035
|
Human Mouse |
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.035
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.035
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.034
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.034
|
Human Mouse |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.034
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.034
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.034
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.034
|
Human Mouse Rat |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.034
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.034
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.034
|
Mouse Worm |
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.033
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.033
|
|
|
|
regulation of catenin import into nucleus
|
GO:0035412 |
18 |
0.033
|
Human |
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
26 |
0.033
|
Mouse |
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.033
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.033
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.032
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.032
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.032
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.032
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.032
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.031
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.031
|
|
|
|
inorganic anion transport
|
GO:0015698 |
60 |
0.031
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.031
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.031
|
Human |
|
|
regulation of fat cell differentiation
|
GO:0045598 |
23 |
0.031
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.031
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.031
|
|
|
|
palate development
|
GO:0060021 |
13 |
0.031
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.031
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.031
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.030
|
|
|
|
cardiac chamber development
|
GO:0003205 |
30 |
0.030
|
Mouse |
|
|
protein processing
|
GO:0016485 |
226 |
0.030
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.030
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.030
|
Mouse |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.030
|
Mouse |
|
|
specification of organ identity
|
GO:0010092 |
3 |
0.030
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.030
|
Human Mouse |
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.030
|
Human Mouse |
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.029
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.029
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.029
|
Zebrafish |
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.029
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.029
|
Mouse |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.029
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.029
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.029
|
Human Mouse |
|
|
cation transport
|
GO:0006812 |
331 |
0.029
|
Zebrafish |
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.029
|
Human Mouse |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.029
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.029
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.028
|
Zebrafish |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.028
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.028
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.028
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.028
|
|
|
|
positive regulation of keratinocyte migration
|
GO:0051549 |
4 |
0.028
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.028
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.028
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.028
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.028
|
|
|
|
forebrain regionalization
|
GO:0021871 |
3 |
0.028
|
Human |
|
|
urogenital system development
|
GO:0001655 |
65 |
0.028
|
Mouse Rat |
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.028
|
Mouse Worm |
|
|
nerve development
|
GO:0021675 |
4 |
0.028
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.028
|
Zebrafish |
|
|
regulation of keratinocyte apoptotic process
|
GO:1902172 |
1 |
0.027
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.027
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.027
|
Human Mouse |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.027
|
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.027
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.027
|
|
|
|
camera type eye development
|
GO:0043010 |
25 |
0.027
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.027
|
|
|
|
regulation of epithelial cell differentiation
|
GO:0030856 |
24 |
0.027
|
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
6 |
0.027
|
Human |
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.027
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.026
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.026
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.026
|
Zebrafish |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.026
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.026
|
Human Zebrafish Mouse |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.026
|
|
|
|
regulation of anion transport
|
GO:0044070 |
25 |
0.026
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.026
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.025
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.025
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.025
|
Human Mouse Worm |
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.025
|
Human Mouse Rat |
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.025
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.025
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.025
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.025
|
Zebrafish |
|
|
positive regulation of ossification
|
GO:0045778 |
32 |
0.025
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.025
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.024
|
Zebrafish |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.024
|
|
|
|
head development
|
GO:0060322 |
108 |
0.024
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.024
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.024
|
|
|
|
cardiac muscle cell contraction
|
GO:0086003 |
4 |
0.024
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.024
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.024
|
|
|
|
mating
|
GO:0007618 |
1 |
0.024
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.024
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.024
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.024
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.024
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.024
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.024
|
Zebrafish Mouse |
|
|
dermatome development
|
GO:0061054 |
3 |
0.024
|
Human |
|
|
negative regulation of embryonic development
|
GO:0045992 |
4 |
0.024
|
Mouse |
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.024
|
Zebrafish |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.024
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.023
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.023
|
|
|
|
cgmp metabolic process
|
GO:0046068 |
19 |
0.023
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.023
|
|
|
|
regulation of cgmp metabolic process
|
GO:0030823 |
9 |
0.023
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.023
|
Mouse |
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.023
|
Human |
|
|
cartilage development
|
GO:0051216 |
31 |
0.023
|
Human Zebrafish Mouse |
|
|
regulation of dermatome development
|
GO:0061183 |
3 |
0.023
|
Human |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.023
|
|
|
|
phosphate ion transport
|
GO:0006817 |
7 |
0.023
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.023
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.023
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.023
|
Mouse |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.023
|
Human |
|
|
glial cell migration
|
GO:0008347 |
4 |
0.023
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.023
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.023
|
Zebrafish |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.023
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.023
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.023
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.022
|
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.022
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.022
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.022
|
Human |
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.022
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.022
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.022
|
Zebrafish |
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.022
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.022
|
Rat |
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.022
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.022
|
Human |
|
|
response to peptide
|
GO:1901652 |
65 |
0.022
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.022
|
|
|
|
memory
|
GO:0007613 |
3 |
0.022
|
|
|
|
response to acid chemical
|
GO:0001101 |
66 |
0.022
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.022
|
|
|
|
muscle organ morphogenesis
|
GO:0048644 |
19 |
0.022
|
Mouse |
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.022
|
Zebrafish |
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.022
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.022
|
|
|
|
positive regulation of epidermis development
|
GO:0045684 |
11 |
0.022
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.022
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.021
|
Mouse |
|
|
cardiac ventricle development
|
GO:0003231 |
23 |
0.021
|
Mouse |
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
89 |
0.021
|
Zebrafish |
