|
|
negative regulation of sodium ion transmembrane transport
|
GO:1902306 |
2 |
0.984
|
Human |
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
0.974
|
Human |
|
|
receptor catabolic process
|
GO:0032801 |
11 |
0.943
|
Human |
|
|
development involved in symbiotic interaction
|
GO:0044111 |
1 |
0.908
|
Human |
|
|
negative regulation of sodium ion transport
|
GO:0010766 |
3 |
0.897
|
Human |
|
|
negative regulation of sodium ion transmembrane transporter activity
|
GO:2000650 |
2 |
0.887
|
Human |
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.879
|
Yeast |
|
|
polyprenol biosynthetic process
|
GO:0016094 |
1 |
0.878
|
Yeast |
|
|
ribosomal large subunit export from nucleus
|
GO:0000055 |
3 |
0.874
|
Yeast |
|
|
trna transport
|
GO:0051031 |
1 |
0.861
|
Yeast |
|
|
ubiquitin dependent endocytosis
|
GO:0070086 |
1 |
0.855
|
Yeast |
|
|
dolichol metabolic process
|
GO:0019348 |
3 |
0.840
|
Yeast |
|
|
regulation of cofactor metabolic process
|
GO:0051193 |
3 |
0.837
|
Yeast |
|
|
regulation of mrna export from nucleus
|
GO:0010793 |
3 |
0.807
|
Yeast |
|
|
hard palate development
|
GO:0060022 |
1 |
0.796
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.788
|
Human Yeast Mouse |
|
|
transmission of virus
|
GO:0019089 |
1 |
0.770
|
Human |
|
|
regulation of rrna processing
|
GO:2000232 |
1 |
0.764
|
Yeast |
|
|
fatty acid biosynthetic process
|
GO:0006633 |
46 |
0.745
|
Yeast |
|
|
trna export from nucleus
|
GO:0006409 |
1 |
0.738
|
Yeast |
|
|
rrna containing ribonucleoprotein complex export from nucleus
|
GO:0071428 |
4 |
0.726
|
Yeast |
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.722
|
Human |
|
|
regulation of ketone biosynthetic process
|
GO:0010566 |
7 |
0.660
|
Yeast |
|
|
ubiquitin dependent smad protein catabolic process
|
GO:0030579 |
4 |
0.646
|
Human |
|
|
regulation of ribosome biogenesis
|
GO:0090069 |
1 |
0.612
|
Yeast |
|
|
dolichol biosynthetic process
|
GO:0019408 |
1 |
0.586
|
Yeast |
|
|
regulation of transcription from rna polymerase ii promoter in response to uv induced dna damage
|
GO:0010767 |
1 |
0.576
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.572
|
Yeast |
|
|
polyprenol metabolic process
|
GO:0016093 |
3 |
0.563
|
Yeast |
|
|
ribonucleoprotein complex localization
|
GO:0071166 |
4 |
0.555
|
Yeast |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.500
|
Human |
|
|
dissemination or transmission of symbiont from host
|
GO:0044007 |
1 |
0.497
|
Human |
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.495
|
Human |
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.495
|
Human |
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.490
|
Yeast |
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.473
|
Yeast |
|
|
protein localization to lysosome
|
GO:0061462 |
11 |
0.453
|
Human |
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.443
|
Human |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.437
|
Yeast |
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.430
|
Yeast |
|
|
regulation of isoprenoid metabolic process
|
GO:0019747 |
1 |
0.425
|
Yeast |
|
|
dissemination or transmission of organism from other organism involved in symbiotic interaction
|
GO:0051821 |
1 |
0.415
|
Human |
|
|
negative regulation of ion transmembrane transport
|
GO:0034766 |
26 |
0.415
|
Human |
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.378
|
Human |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.367
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.354
|
Human |
|
|
ribonucleoprotein complex export from nucleus
|
GO:0071426 |
4 |
0.352
|
Yeast |
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.350
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.350
|
Yeast |
|
|
negative regulation of transmembrane transport
|
GO:0034763 |
29 |
0.347
|
Human |
|
|
oxidoreduction coenzyme metabolic process
|
GO:0006733 |
19 |
0.345
|
Yeast |
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.337
|
Human Yeast Mouse |
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.326
|
Human |
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.324
|
Yeast |
|
|
quinone metabolic process
|
GO:1901661 |
18 |
0.324
|
Yeast |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.320
|
Human Yeast Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.312
|
Human Yeast |
|
|
regulation of protein localization to cell surface
|
GO:2000008 |
15 |
0.308
|
Human |
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.304
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.298
|
Human |
|
|
coenzyme biosynthetic process
|
GO:0009108 |
24 |
0.297
|
Yeast |
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.297
|
Yeast |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.296
|
Human Yeast Mouse Worm |
|
|
regulation of potassium ion transmembrane transport
|
GO:1901379 |
20 |
0.295
|
Human |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.293
|
Human Yeast Mouse |
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.293
|
Human |
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.289
|
Human |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.285
|
Human |
|
|
smad protein complex assembly
|
GO:0007183 |
12 |
0.282
|
|
|
|
protein k29 linked ubiquitination
|
GO:0035519 |
4 |
0.270
|
Human |
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.259
|
Yeast |
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.258
|
Human Yeast Mouse Worm |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.256
|
Human Yeast |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.255
|
Yeast |
|
|
organelle localization
|
GO:0051640 |
84 |
0.232
|
Yeast |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.225
|
Yeast |
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.225
|
Human |
|
|
cofactor biosynthetic process
|
GO:0051188 |
31 |
0.223
|
Yeast |
|
|
regulation of sodium ion transmembrane transport
|
GO:1902305 |
23 |
0.221
|
Human |
|
|
defense response
|
GO:0006952 |
315 |
0.219
|
Human |
|
|
ribosomal subunit export from nucleus
|
GO:0000054 |
4 |
0.218
|
Yeast |
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.200
|
Yeast |
|
|
regulation of potassium ion transmembrane transporter activity
|
GO:1901016 |
16 |
0.200
|
Human |
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.195
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.193
|
|
|
|
regulation of sodium ion transport
|
GO:0002028 |
24 |
0.193
|
Human |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.192
|
Human |
|
|
regulation of endosome size
|
GO:0051036 |
3 |
0.192
|
Yeast |
|
|
negative regulation of ion transmembrane transporter activity
|
GO:0032413 |
19 |
0.191
|
Human |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.190
|
Human |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.187
|
Human Yeast Fly |
|
|
regulation of multivesicular body size
|
GO:0010796 |
1 |
0.186
|
Yeast |
|
|
isoprenoid biosynthetic process
|
GO:0008299 |
9 |
0.177
|
Yeast |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.176
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.173
|
Human |
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.170
|
Yeast |
|
|
nervous system development
|
GO:0007399 |
293 |
0.169
|
Human Worm |
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.165
|
Yeast |
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.165
|
Human Yeast Worm |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.162
|
Human |
|
|
regulation of steroid biosynthetic process
|
GO:0050810 |
23 |
0.161
|
Yeast |
|
|
response to radiation
|
GO:0009314 |
151 |
0.158
|
Human Yeast |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.158
|
Human Yeast |
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.155
|
Human |
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.154
|
Yeast |
|
|
endosome transport via multivesicular body sorting pathway
|
GO:0032509 |
3 |
0.153
|
Yeast |
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.150
|
Yeast |
|
|
heart development
|
GO:0007507 |
95 |
0.149
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.148
|
Human |
|
|
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway
|
GO:0043162 |
10 |
0.148
|
Human Yeast |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.147
|
Human Yeast Mouse |
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.145
|
Human |
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.142
|
Human |
|
|
metal ion transport
|
GO:0030001 |
272 |
0.139
|
Human |
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.138
|
Yeast |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.136
|
Human Yeast |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.135
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.134
|
Human |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.134
|
Human |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.133
|
Human Yeast Mouse |
|
|
endosomal transport
|
GO:0016197 |
129 |
0.133
|
Yeast |
|
|
nuclear export
|
GO:0051168 |
69 |
0.133
|
Human Yeast |
|
|
stem cell division
|
GO:0017145 |
2 |
0.132
|
|
|
|
rna polyadenylation
|
GO:0043631 |
14 |
0.132
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.132
|
Human |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.128
|
Human Yeast Mouse Worm |
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.128
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.127
|
Human |
|
|
alcohol biosynthetic process
|
GO:0046165 |
52 |
0.125
|
Yeast |
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.125
|
Yeast |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.123
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.123
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.120
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.118
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.118
|
Human |
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.118
|
Human |
|
|
regulation of membrane depolarization
|
GO:0003254 |
19 |
0.117
|
Human |
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.116
|
Human |
|
|
establishment of ribosome localization
|
GO:0033753 |
4 |
0.116
|
Yeast |
|
|
protein k63 linked ubiquitination
|
GO:0070534 |
31 |
0.116
|
Human |
|
|
steroid biosynthetic process
|
GO:0006694 |
46 |
0.114
|
Yeast |
|
|
negative regulation of potassium ion transmembrane transport
|
GO:1901380 |
5 |
0.113
|
Human |
|
|
regulation of fatty acid metabolic process
|
GO:0019217 |
24 |
0.112
|
Yeast |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.112
|
Human |
|
|
defense response to virus
|
GO:0051607 |
71 |
0.111
|
Human |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.111
|
Yeast |
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.109
|
Yeast |
|
|
regulation of membrane repolarization
|
GO:0060306 |
16 |
0.107
|
Human |
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.106
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.105
|
Human |
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.103
|
Human Fly |
|
|
negative regulation of transporter activity
|
GO:0032410 |
25 |
0.103
|
Human |
|
|
positive regulation of fatty acid biosynthetic process
|
GO:0045723 |
5 |
0.101
|
Yeast |
|
|
corticosteroid receptor signaling pathway
|
GO:0031958 |
5 |
0.101
|
Human |
|
|
viral process
|
GO:0016032 |
146 |
0.100
|
Human |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.096
|
Human Yeast |
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.095
|
Human |
|
|
regulation of ion homeostasis
|
GO:2000021 |
73 |
0.095
|
Human |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.095
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.094
|
Human |
|
|
ribosome localization
|
GO:0033750 |
4 |
0.094
|
Yeast |
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.093
|
Yeast |
|
|
progesterone receptor signaling pathway
|
GO:0050847 |
3 |
0.093
|
Human |
|
|
negative regulation of protein localization to cell surface
|
GO:2000009 |
5 |
0.092
|
Human |
|
|
vasculature development
|
GO:0001944 |
181 |
0.090
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.090
|
Yeast |
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.089
|
Human |
|
|
regulation of potassium ion transport
|
GO:0043266 |
24 |
0.089
|
Human |
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.089
|
Human |
|
|
regulation of sodium ion transmembrane transporter activity
|
GO:2000649 |
17 |
0.088
|
Human |
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.087
|
Human |
|
|
autophagy
|
GO:0006914 |
88 |
0.087
|
Yeast |
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.086
|
|
|
|
ncrna processing
|
GO:0034470 |
83 |
0.085
|
Yeast |
|
|
protein acylation
|
GO:0043543 |
138 |
0.084
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.083
|
Yeast |
|
|
negative regulation of potassium ion transport
|
GO:0043267 |
6 |
0.082
|
Human |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.082
|
Human |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.082
|
Human |
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.082
|
|
|
|
establishment of protein localization to vacuole
|
GO:0072666 |
8 |
0.081
|
Human |
|
|
mrna transport
|
GO:0051028 |
30 |
0.081
|
Yeast |
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.080
|
Yeast |
|
|
regulation of coenzyme metabolic process
|
GO:0051196 |
3 |
0.080
|
Yeast |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.078
|
Human Yeast Mouse |
|
|
regulation of alcohol biosynthetic process
|
GO:1902930 |
22 |
0.077
|
Yeast |
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.076
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.076
|
Human |
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.075
|
Human |
|
|
regulation of defense response to virus
|
GO:0050688 |
33 |
0.075
|
Human |
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.073
|
Yeast |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.072
|
Human |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.072
|
|
|
|
lysosomal transport
|
GO:0007041 |
33 |
0.071
|
Human |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.070
|
Yeast |
|
|
immune system development
|
GO:0002520 |
195 |
0.069
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
0.069
|
Human |
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.068
|
Human |
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.067
|
Yeast |
|
|
immune effector process
|
GO:0002252 |
159 |
0.067
|
Human |
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.067
|
Human |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.066
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.066
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.065
|
Yeast |
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.065
|
Human |
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.065
|
|
|
|
membrane repolarization
|
GO:0086009 |
23 |
0.065
|
Human |
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.064
|
Human |
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.064
|
Yeast |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.064
|
Human |
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.064
|
Yeast |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.063
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
38 |
0.063
|
Human |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.062
|
Human Yeast |
|
|
positive regulation of fatty acid metabolic process
|
GO:0045923 |
11 |
0.061
|
Yeast |
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.061
|
|
|
|
establishment of rna localization
|
GO:0051236 |
39 |
0.060
|
Yeast |
|
|
growth
|
GO:0040007 |
202 |
0.060
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.060
|
Human |
|
|
histone modification
|
GO:0016570 |
251 |
0.059
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.059
|
Fly |
|
|
response to uv
|
GO:0009411 |
73 |
0.059
|
Human Yeast |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.059
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.058
|
Human |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.058
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.058
|
Human |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.058
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.058
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.057
|
Human |
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.055
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.055
|
Human |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.055
|
Yeast |
|
|
negative regulation of potassium ion transmembrane transporter activity
|
GO:1901017 |
3 |
0.054
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.054
|
Human |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.054
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.053
|
Human Yeast |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.053
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.053
|
Yeast |
|
|
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus
|
GO:1901522 |
2 |
0.052
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.052
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.052
|
Human Yeast |
|
|
late endosome to vacuole transport
|
GO:0045324 |
2 |
0.052
|
Yeast |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.051
|
|
|
|
trna processing
|
GO:0008033 |
23 |
0.051
|
Yeast |
|
|
protein localization to vacuole
|
GO:0072665 |
11 |
0.051
|
Human |
|
|
digestive tract development
|
GO:0048565 |
75 |
0.051
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.050
|
Human |
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.050
|
|
|
|
otic vesicle development
|
GO:0071599 |
1 |
0.050
|
|
|
|
endocardial cushion development
|
GO:0003197 |
3 |
0.050
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.049
|
Yeast |
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.048
|
Yeast |
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.048
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.048
|
Human Yeast |
|
|
protein autoubiquitination
|
GO:0051865 |
37 |
0.048
|
Human Yeast |
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.046
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.046
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.046
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.045
|
|
|
|
receptor internalization
|
GO:0031623 |
43 |
0.045
|
Human Fly |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.044
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.044
|
Human |
|
|
protein localization to endoplasmic reticulum
|
GO:0070972 |
19 |
0.044
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.044
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.043
|
|
|
|
protein targeting to lysosome
|
GO:0006622 |
8 |
0.043
|
Human |
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.043
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.042
|
Human |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.042
|
|
|
|
sterol biosynthetic process
|
GO:0016126 |
10 |
0.042
|
Yeast |
|
|
system process
|
GO:0003008 |
349 |
0.041
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.041
|
Worm |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.041
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.041
|
|
|
|
interaction with host
|
GO:0051701 |
42 |
0.040
|
Human |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.040
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.040
|
Yeast |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.040
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.040
|
Human |
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.039
|
|
|
|
rna localization
|
GO:0006403 |
41 |
0.039
|
Yeast |
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.039
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.039
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.038
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.038
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.038
|
Yeast |
|
|
cell division
|
GO:0051301 |
168 |
0.038
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.038
|
|
|
|
ubiquinone metabolic process
|
GO:0006743 |
5 |
0.038
|
Yeast |
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
67 |
0.037
|
Yeast |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.037
|
|
|
|
positive regulation of lipid biosynthetic process
|
GO:0046889 |
22 |
0.037
|
Yeast |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.036
|
Human |
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.035
|
Human |
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.035
|
|
|
|
quinone biosynthetic process
|
GO:1901663 |
6 |
0.035
|
Yeast |
|
|
protein export from nucleus
|
GO:0006611 |
29 |
0.035
|
Human |
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.035
|
Yeast |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.035
|
Human Yeast |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.034
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.034
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.034
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.034
|
|
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
4 |
0.034
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.034
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.034
|
Human |
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.034
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
3 |
0.034
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.033
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.033
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.033
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.032
|
Yeast |
|
|
spinal cord development
|
GO:0021510 |
4 |
0.032
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.032
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.032
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.031
|
Human Worm |
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.031
|
Human |
|
|
negative regulation of defense response to virus
|
GO:0050687 |
10 |
0.031
|
Human |
|
|
rna export from nucleus
|
GO:0006405 |
33 |
0.030
|
Yeast |
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.030
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.030
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.030
|
|
|
|
mrna export from nucleus
|
GO:0006406 |
29 |
0.030
|
Yeast |
|
|
ossification
|
GO:0001503 |
121 |
0.030
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.030
|
Yeast |
|
|
negative regulation of axonogenesis
|
GO:0050771 |
4 |
0.030
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.029
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.029
|
Human Yeast |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.029
|
|
|
|
regulation of steroid metabolic process
|
GO:0019218 |
32 |
0.029
|
Yeast |
|
|
circulatory system development
|
GO:0072359 |
262 |
0.029
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.029
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.029
|
|
|
|
cellular response to light stimulus
|
GO:0071482 |
34 |
0.029
|
Human Yeast |
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.029
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.028
|
Human |
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.028
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.028
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
3 |
0.028
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.028
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.028
|
Human |
|
|
muscle system process
|
GO:0003012 |
81 |
0.028
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.028
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.028
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.028
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.027
|
Human |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.027
|
Human |
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.027
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.027
|
Human Yeast Worm |
|
|
membrane organization
|
GO:0061024 |
292 |
0.027
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.027
|
Human Yeast |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.026
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.026
|
Yeast |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.026
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.026
|
Human |
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.026
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.026
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.026
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.026
|
Yeast |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.025
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.025
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.025
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.025
|
Human Yeast |
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.025
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.025
|
Yeast |
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.024
|
Yeast |
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.024
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.024
|
Human Yeast |
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.024
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.024
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.024
|
Human |
|
|
sterol metabolic process
|
GO:0016125 |
28 |
0.023
|
Yeast |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.023
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.023
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.023
|
Human Yeast |
|
|
protein processing
|
GO:0016485 |
226 |
0.023
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.023
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.023
|
|
|
|
ketone biosynthetic process
|
GO:0042181 |
17 |
0.023
|
Yeast |
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.023
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.023
|
|
|
|
negative regulation of response to biotic stimulus
|
GO:0002832 |
18 |
0.023
|
Human |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.023
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.023
|
Yeast |
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.023
|
Human |
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.023
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.023
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.023
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.022
|
|
|
|
rna 3 end processing
|
GO:0031123 |
35 |
0.022
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.022
|
Human Worm |
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.022
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.022
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.022
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.022
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.022
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.022
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.022
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.022
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.022
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.022
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.022
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.022
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.022
|
Worm |
|
|
innate immune response
|
GO:0045087 |
178 |
0.021
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.021
|
Human |
|
|
cellular modified amino acid biosynthetic process
|
GO:0042398 |
15 |
0.021
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.021
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.021
|
Human |
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.021
|
Human |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.021
|
Yeast |
|
|
ubiquinone biosynthetic process
|
GO:0006744 |
5 |
0.021
|
Yeast |
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.021
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.021
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.021
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.021
|
Human Yeast |
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.021
|
|
|
|
spinal cord dorsal ventral patterning
|
GO:0021513 |
2 |
0.021
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.021
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.020
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.020
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.020
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.020
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.020
|
|
|
|
anoikis
|
GO:0043276 |
22 |
0.020
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.020
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.020
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.020
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.020
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.020
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.020
|
|
|
|
negative regulation of smad protein complex assembly
|
GO:0010991 |
4 |
0.019
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.019
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
0.019
|
|
|
|
convergent extension involved in gastrulation
|
GO:0060027 |
1 |
0.019
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.019
|
|
|
|
positive regulation of response to dna damage stimulus
|
GO:2001022 |
43 |
0.019
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.019
|
Fly |
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.019
|
|
|
|
ribosome biogenesis
|
GO:0042254 |
48 |
0.019
|
Yeast |
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.019
|
Yeast |
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.019
|
Yeast |
|
|
convergent extension
|
GO:0060026 |
1 |
0.018
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.018
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.018
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.018
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.018
|
|
|
|
positive regulation of receptor mediated endocytosis
|
GO:0048260 |
21 |
0.018
|
Yeast |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.018
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.018
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.018
|
|
|
|
zygotic specification of dorsal ventral axis
|
GO:0007352 |
2 |
0.018
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.018
|
Human |
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.018
|
Human |
|
|
nerve development
|
GO:0021675 |
4 |
0.018
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.018
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.018
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.018
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.017
|
|
|
|
cell proliferation involved in heart valve development
|
GO:2000793 |
1 |
0.017
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.017
|
Human |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.017
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.017
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.017
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.017
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.017
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.017
|
Human |
|
|
endocytosis
|
GO:0006897 |
159 |
0.017
|
Human Yeast Fly |
|
|
negative regulation of axon extension
|
GO:0030517 |
2 |
0.017
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.017
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.017
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.017
|
Worm |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.017
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.017
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.017
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.017
|
|
|
|
ncrna metabolic process
|
GO:0034660 |
108 |
0.017
|
Yeast |
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.017
|
Yeast |
|
|
embryo development
|
GO:0009790 |
123 |
0.016
|
Worm |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.016
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.016
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
17 |
0.016
|
Human |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.016
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.016
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.016
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.016
|
|
|
|
rna transport
|
GO:0050658 |
39 |
0.016
|
Yeast |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.016
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.016
|
|
|
|
regulation of mitochondrial membrane potential
|
GO:0051881 |
23 |
0.016
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.016
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.016
|
|
