|
|
bmp signaling pathway involved in heart development
|
GO:0061312 |
3 |
1.000
|
|
|
|
endodermal mesodermal cell signaling
|
GO:0003133 |
3 |
1.000
|
|
|
|
regulation of heart induction by regulation of canonical wnt signaling pathway
|
GO:0090081 |
1 |
1.000
|
|
|
|
cardiac cell fate determination
|
GO:0060913 |
3 |
1.000
|
|
|
|
regulation of methylation dependent chromatin silencing
|
GO:0090308 |
3 |
1.000
|
|
|
|
extraocular skeletal muscle development
|
GO:0002074 |
1 |
0.999
|
|
|
|
ectodermal cell fate commitment
|
GO:0001712 |
1 |
0.998
|
|
|
|
negative regulation of posttranscriptional gene silencing
|
GO:0060149 |
3 |
0.997
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.995
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.993
|
|
|
|
negative regulation of gene silencing by rna
|
GO:0060967 |
3 |
0.991
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.989
|
|
|
|
trophectodermal cell differentiation
|
GO:0001829 |
3 |
0.989
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.989
|
Human |
|
|
viral process
|
GO:0016032 |
146 |
0.987
|
Human |
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.986
|
Human |
|
|
trna processing
|
GO:0008033 |
23 |
0.985
|
Yeast |
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.976
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.969
|
Human |
|
|
endodermal mesodermal cell signaling involved in heart induction
|
GO:0003134 |
3 |
0.965
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.964
|
Human |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.949
|
Human |
|
|
ribosomal large subunit export from nucleus
|
GO:0000055 |
3 |
0.941
|
Yeast |
|
|
negative regulation of gene silencing by mirna
|
GO:0060965 |
3 |
0.941
|
|
|
|
dolichol biosynthetic process
|
GO:0019408 |
1 |
0.939
|
Yeast |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.936
|
Yeast |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.935
|
Human Yeast |
|
|
bmp signaling pathway involved in heart induction
|
GO:0003130 |
3 |
0.929
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.919
|
|
|
|
regulation of wnt signaling pathway involved in heart development
|
GO:0003307 |
3 |
0.903
|
|
|
|
trna transport
|
GO:0051031 |
1 |
0.893
|
Yeast |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.893
|
Human |
|
|
gene silencing by mirna
|
GO:0035195 |
23 |
0.891
|
|
|
|
receptor catabolic process
|
GO:0032801 |
11 |
0.890
|
Human |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.889
|
Human Yeast |
|
|
protein targeting
|
GO:0006605 |
187 |
0.887
|
Human |
|
|
regulation of mrna export from nucleus
|
GO:0010793 |
3 |
0.887
|
Yeast |
|
|
negative regulation of sodium ion transmembrane transport
|
GO:1902306 |
2 |
0.877
|
Human |
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.873
|
Human Yeast |
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.873
|
Human |
|
|
positive regulation of mesenchymal stem cell differentiation
|
GO:2000741 |
4 |
0.859
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.851
|
Human |
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.828
|
Human Yeast |
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.826
|
|
|
|
negative regulation of sodium ion transmembrane transporter activity
|
GO:2000650 |
2 |
0.825
|
Human |
|
|
regulation of smad protein import into nucleus
|
GO:0060390 |
10 |
0.824
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.823
|
Human |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.822
|
Human |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.819
|
Human |
|
|
specification of organ identity
|
GO:0010092 |
3 |
0.810
|
|
|
|
blastocyst formation
|
GO:0001825 |
3 |
0.807
|
|
|
|
menstrual cycle phase
|
GO:0022601 |
2 |
0.806
|
|
|
|
quinone biosynthetic process
|
GO:1901663 |
6 |
0.799
|
Yeast |
|
|
negative regulation of sodium ion transport
|
GO:0010766 |
3 |
0.790
|
Human |
|
|
coenzyme biosynthetic process
|
GO:0009108 |
24 |
0.778
|
Yeast |
|
|
ectoderm formation
|
GO:0001705 |
1 |
0.778
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.773
|
Human |
|
|
mesodermal cell fate commitment
|
GO:0001710 |
2 |
0.768
|
|
|
|
trna export from nucleus
|
GO:0006409 |
1 |
0.766
|
Yeast |
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.754
|
Human |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.753
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.747
|
|
|
|
regulation of rrna processing
|
GO:2000232 |
1 |
0.733
|
Yeast |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.729
|
Yeast |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.712
|
Human |
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.708
|
|
|
|
progesterone receptor signaling pathway
|
GO:0050847 |
3 |
0.704
|
Human |
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.688
|
|
|
|
polyprenol biosynthetic process
|
GO:0016094 |
1 |
0.675
|
Yeast |
|
|
positive regulation of fatty acid biosynthetic process
|
GO:0045723 |
5 |
0.671
|
Yeast |
|
|
stem cell development
|
GO:0048864 |
69 |
0.662
|
|
|
|
regulation of ketone biosynthetic process
|
GO:0010566 |
7 |
0.658
|
Yeast |
|
|
positive regulation of male gonad development
|
GO:2000020 |
3 |
0.656
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.651
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.650
|
|
|
|
regulation of heart induction
|
GO:0090381 |
2 |
0.646
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.638
|
|
|
|
isoprenoid biosynthetic process
|
GO:0008299 |
9 |
0.637
|
Yeast |
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.634
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.633
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.620
|
|
|
|
rrna containing ribonucleoprotein complex export from nucleus
|
GO:0071428 |
4 |
0.618
|
Yeast |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.609
|
Human Yeast |
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.601
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter in response to uv induced dna damage
|
GO:0010768 |
1 |
0.598
|
Human |
|
|
mrna transcription from rna polymerase ii promoter
|
GO:0042789 |
6 |
0.596
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.594
|
|
|
|
dissemination or transmission of symbiont from host
|
GO:0044007 |
1 |
0.591
|
Human |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.575
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.556
|
|
|
|
regulation of cofactor metabolic process
|
GO:0051193 |
3 |
0.548
|
Yeast |
|
|
menstruation
|
GO:0042703 |
1 |
0.542
|
|
|
|
ectoderm development
|
GO:0007398 |
3 |
0.538
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.529
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.526
|
|
|
|
regulation of ribosome biogenesis
|
GO:0090069 |
1 |
0.521
|
Yeast |
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.519
|
|
|
|
cartilage development involved in endochondral bone morphogenesis
|
GO:0060351 |
2 |
0.518
|
|
|
|
positive regulation of smad protein import into nucleus
|
GO:0060391 |
8 |
0.511
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.501
|
Yeast |
|
|
ubiquitin dependent endocytosis
|
GO:0070086 |
1 |
0.496
|
Yeast |
|
|
oxidoreduction coenzyme metabolic process
|
GO:0006733 |
19 |
0.494
|
Yeast |
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.493
|
|
|
|
regulation of cartilage development
|
GO:0061035 |
12 |
0.489
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.486
|
Mouse |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.483
|
Human |
|
|
endosome transport via multivesicular body sorting pathway
|
GO:0032509 |
3 |
0.479
|
Yeast |
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.474
|
Yeast |
|
|
heart induction
|
GO:0003129 |
4 |
0.470
|
|
|
|
methylation dependent chromatin silencing
|
GO:0006346 |
3 |
0.457
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.449
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.444
|
Human |
|
|
negative regulation of protein localization to cell surface
|
GO:2000009 |
5 |
0.443
|
Human |
|
|
soft palate development
|
GO:0060023 |
3 |
0.442
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.440
|
Yeast |
|
|
regulation of endosome size
|
GO:0051036 |
3 |
0.438
|
Yeast |
|
|
protein export from nucleus
|
GO:0006611 |
29 |
0.435
|
Human |
|
|
posttranscriptional gene silencing by rna
|
GO:0035194 |
25 |
0.435
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.428
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.418
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.417
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
46 |
0.416
|
|
|
|
regulation of heart morphogenesis
|
GO:2000826 |
4 |
0.416
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.413
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.409
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.409
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.406
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.396
|
|
|
|
development involved in symbiotic interaction
|
GO:0044111 |
1 |
0.389
|
Human |
|
|
regulation of isoprenoid metabolic process
|
GO:0019747 |
1 |
0.383
|
Yeast |
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.382
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.380
|
Human |
|
|
ectodermal placode development
|
GO:0071696 |
1 |
0.376
|
|
|
|
polyprenol metabolic process
|
GO:0016093 |
3 |
0.375
|
Yeast |
|
|
chromatin assembly
|
GO:0031497 |
61 |
0.375
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.374
|
Human |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.373
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.373
|
Human |
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.370
|
Human Yeast Mouse |
|
|
gastrulation
|
GO:0007369 |
51 |
0.370
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.361
|
|
|
|
ncrna processing
|
GO:0034470 |
83 |
0.360
|
Yeast |
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.351
|
|
|
|
ribonucleoprotein complex localization
|
GO:0071166 |
4 |
0.349
|
Yeast |
|
|
regulation of chondrocyte differentiation
|
GO:0032330 |
9 |
0.345
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.338
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.332
|
|
|
|
viral gene expression
|
GO:0019080 |
35 |
0.328
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.324
|
|
|
|
heart field specification
|
GO:0003128 |
2 |
0.321
|
|
|
|
enteric nervous system development
|
GO:0048484 |
1 |
0.318
|
|
|
|
dissemination or transmission of organism from other organism involved in symbiotic interaction
|
GO:0051821 |
1 |
0.310
|
Human |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.308
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.308
|
Human Yeast |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.303
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.294
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.293
|
Human |
|
|
blastocyst development
|
GO:0001824 |
3 |
0.280
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.280
|
Human Yeast |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.279
|
|
|
|
base conversion or substitution editing
|
GO:0016553 |
4 |
0.279
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.277
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.276
|
Human |
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.274
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.270
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.269
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.267
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.266
|
|
|
|
organ induction
|
GO:0001759 |
4 |
0.265
|
|
|
|
regulation of multivesicular body size
|
GO:0010796 |
1 |
0.263
|
Yeast |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.256
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.255
|
Yeast |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.255
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.254
|
|
|
|
smad protein import into nucleus
|
GO:0007184 |
13 |
0.249
|
|
|
|
transmission of virus
|
GO:0019089 |
1 |
0.244
|
Human |
|
|
mrna transcription
|
GO:0009299 |
8 |
0.242
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.240
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.237
|
Yeast |
|
|
late endosome to vacuole transport
|
GO:0045324 |
2 |
0.235
|
Yeast |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.235
|
|
|
|
ncrna metabolic process
|
GO:0034660 |
108 |
0.234
|
Yeast |
|
|
posttranscriptional gene silencing
|
GO:0016441 |
25 |
0.234
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.234
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to uv induced dna damage
|
GO:0010767 |
1 |
0.233
|
Human |
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
2 |
0.233
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.231
|
Yeast |
|
|
embryo development
|
GO:0009790 |
123 |
0.227
|
Worm |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.225
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.224
|
Yeast |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.223
|
Yeast |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.219
|
Human |
|
|
negative regulation of potassium ion transmembrane transport
|
GO:1901380 |
5 |
0.213
|
Human |
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
0.208
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.206
|
|
|
|
establishment of ribosome localization
|
GO:0033753 |
4 |
0.202
|
Yeast |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.202
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.202
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.202
|
|
|
|
mrna transport
|
GO:0051028 |
30 |
0.201
|
Yeast |
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.201
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.199
|
Yeast |
|
|
regulation of calcium ion dependent exocytosis
|
GO:0017158 |
8 |
0.199
|
|
|
|
modulation by host of symbiont transcription
|
GO:0052472 |
20 |
0.198
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
43 |
0.198
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.198
|
Human Yeast |
|
|
catenin import into nucleus
|
GO:0035411 |
18 |
0.194
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.193
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.191
|
|
|
|
neural crest cell migration
|
GO:0001755 |
2 |
0.190
|
|
|
|
pigmentation
|
GO:0043473 |
22 |
0.189
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.187
|
|
|
|
mrna export from nucleus
|
GO:0006406 |
29 |
0.187
|
Yeast |
|
|
nuclear export
|
GO:0051168 |
69 |
0.186
|
Human Yeast |
|
|
positive regulation of ossification
|
GO:0045778 |
32 |
0.185
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.185
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.182
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.181
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.180
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.179
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.179
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.179
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.179
|
Human |
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.178
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.177
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.176
|
|
|
|
ribosomal subunit export from nucleus
|
GO:0000054 |
4 |
0.175
|
Yeast |
|
|
ossification
|
GO:0001503 |
121 |
0.174
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.173
|
Yeast |
|
|
negative regulation by host of viral transcription
|
GO:0043922 |
12 |
0.173
|
|
|
|
cell surface receptor signaling pathway involved in heart development
|
GO:0061311 |
8 |
0.171
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.171
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.171
|
|
|
|
regulation of gene silencing
|
GO:0060968 |
24 |
0.169
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.167
|
Yeast |
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.166
|
|
|
|
steroid biosynthetic process
|
GO:0006694 |
46 |
0.166
|
Yeast |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.164
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.162
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.162
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.161
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.161
|
Yeast |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.160
|
|
|
|
negative regulation of exocytosis
|
GO:0045920 |
6 |
0.160
|
|
|
|
regulation of fatty acid biosynthetic process
|
GO:0042304 |
9 |
0.160
|
Yeast |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.159
|
|
|
|
nucleosome organization
|
GO:0034728 |
66 |
0.159
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.158
|
Human |
|
|
taxis
|
GO:0042330 |
157 |
0.157
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.157
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.157
|
Yeast |
|
|
quinone metabolic process
|
GO:1901661 |
18 |
0.156
|
Yeast |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.155
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.154
|
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
6 |
0.154
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
24 |
0.151
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.150
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.149
|
|
|
|
sex determination
|
GO:0007530 |
3 |
0.146
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.145
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.145
|
Human Yeast |
|
|
ribonucleoprotein complex export from nucleus
|
GO:0071426 |
4 |
0.144
|
Yeast |
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.143
|
Human |
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
9 |
0.143
|
|
|
|
isoprenoid metabolic process
|
GO:0006720 |
39 |
0.142
|
Yeast |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.141
|
Human |
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.140
|
|
|
|
trna metabolic process
|
GO:0006399 |
35 |
0.139
|
Yeast |
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.138
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.137
|
Human Worm |
|
|
negative regulation of secretion by cell
|
GO:1903531 |
52 |
0.135
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.135
|
|
|
|
sodium ion transport
|
GO:0006814 |
61 |
0.134
|
Human |
|
|
modulation of transcription in other organism involved in symbiotic interaction
|
GO:0052312 |
20 |
0.132
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.132
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.131
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.129
|
|
|
|
regulation of alcohol biosynthetic process
|
GO:1902930 |
22 |
0.129
|
Yeast |
|
|
protein autoubiquitination
|
GO:0051865 |
37 |
0.128
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.128
|
|
|
|
protein targeting to vacuole
|
GO:0006623 |
8 |
0.127
|
Human |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.127
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.125
|
|
|
|
positive regulation of lipid biosynthetic process
|
GO:0046889 |
22 |
0.125
|
Yeast |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.125
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.125
|
Human |
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.124
|
|
|
|
regulation of protein localization to cell surface
|
GO:2000008 |
15 |
0.124
|
Human |
|
|
wnt signaling pathway involved in heart development
|
GO:0003306 |
5 |
0.122
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.121
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.120
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.120
|
Human Yeast |
|
|
chromatin remodeling
|
GO:0006338 |
55 |
0.119
|
|
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
2 |
0.118
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.118
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.117
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.117
|
|
|
|
protein k63 linked ubiquitination
|
GO:0070534 |
31 |
0.116
|
Human Mouse |
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
35 |
0.116
|
Yeast |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.115
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.115
|
|
|
|
regulation of catenin import into nucleus
|
GO:0035412 |
18 |
0.115
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.115
|
|
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.114
|
Yeast |
|
|
regulation of steroid biosynthetic process
|
GO:0050810 |
23 |
0.113
|
Yeast |
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.113
|
Yeast |
|
|
production of mirnas involved in gene silencing by mirna
|
GO:0035196 |
12 |
0.113
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.113
|
|
|
|
signal transduction involved in mitotic cell cycle checkpoint
|
GO:0072413 |
13 |
0.111
|
|
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.111
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.110
|
Yeast |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.110
|
Human |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.110
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.109
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.109
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.109
|
Yeast |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.109
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.108
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.106
|
|
|
|
modification by host of symbiont morphology or physiology
|
GO:0051851 |
26 |
0.106
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.103
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.103
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.103
|
|
|
|
negative regulation of peptidyl threonine phosphorylation
|
GO:0010801 |
6 |
0.103
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.102
|
|
|
|
negative regulation of phosphatase activity
|
GO:0010923 |
61 |
0.102
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.101
|
|
|
|
regulation of potassium ion transmembrane transporter activity
|
GO:1901016 |
16 |
0.101
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.099
|
|
|
|
regulation of viral transcription
|
GO:0046782 |
34 |
0.099
|
|
|
|
regulation of transcription from rna polymerase ii promoter involved in heart development
|
GO:1901213 |
6 |
0.099
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.099
|
Yeast |
|
|
modulation by host of viral transcription
|
GO:0043921 |
20 |
0.098
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.097
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.096
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.095
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.095
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.095
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.095
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.095
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.094
|
Fly |
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.093
|
|
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.093
|
|
|
|
adenosine to inosine editing
|
GO:0006382 |
3 |
0.093
|
|
|
|
alcohol biosynthetic process
|
GO:0046165 |
52 |
0.093
|
Yeast |
|
|
mesodermal cell differentiation
|
GO:0048333 |
10 |
0.092
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.092
|
Yeast |
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
0.092
|
Human |
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.092
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.091
|
Yeast |
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.090
|
Human |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.089
|
Human |
|
|
neural crest cell differentiation
|
GO:0014033 |
5 |
0.088
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.088
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.088
|
Yeast |
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.087
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.087
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.087
|
Yeast |
|
|
spinal cord development
|
GO:0021510 |
4 |
0.086
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.086
|
|
|
|
negative regulation of ion transmembrane transport
|
GO:0034766 |
26 |
0.086
|
Human |
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.085
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.084
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.084
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
45 |
0.083
|
|
|
|
mesenchymal stem cell differentiation
|
GO:0072497 |
8 |
0.083
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.082
|
Fly |
|
|
nervous system development
|
GO:0007399 |
293 |
0.081
|
Human Worm |
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.081
|
Human Yeast Worm |
|
|
ubiquitin dependent smad protein catabolic process
|
GO:0030579 |
4 |
0.081
|
Human |
|
|
heart process
|
GO:0003015 |
62 |
0.081
|
|
|
|
viral transcription
|
GO:0019083 |
35 |
0.080
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.079
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.079
|
Yeast |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.079
|
|
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.079
|
Yeast |
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.079
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.078
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.078
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
33 |
0.078
|
Human |
|
|
cellular response to dsrna
|
GO:0071359 |
19 |
0.078
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.076
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.076
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.075
|
|
|
|
sterol metabolic process
|
GO:0016125 |
28 |
0.075
|
Yeast |
|
|
cofactor biosynthetic process
|
GO:0051188 |
31 |
0.075
|
Yeast |
|
|
gene silencing by rna
|
GO:0031047 |
26 |
0.075
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.075
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.075
|
|
|
|
ubiquinone metabolic process
|
GO:0006743 |
5 |
0.074
|
Yeast |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.074
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.073
|
Yeast |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.073
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.073
|
Yeast |
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.073
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.072
|
Yeast |
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.072
|
Human Yeast |
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.071
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.071
|
|
|
|
equilibrioception
|
GO:0050957 |
6 |
0.070
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.069
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.068
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.068
|
|
|
|
protein k29 linked ubiquitination
|
GO:0035519 |
4 |
0.068
|
Human |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.068
|
|
|
|
multi organism metabolic process
|
GO:0044033 |
41 |
0.068
|
|
|
|
negative regulation of transmembrane transport
|
GO:0034763 |
29 |
0.068
|
Human |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
64 |
0.067
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.066
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
0.066
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.065
|
Human |
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.065
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.065
|
Yeast |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.065
|
|
|
|
negative regulation of protein kinase b signaling
|
GO:0051898 |
17 |
0.064
|
|
|
|
rna export from nucleus
|
GO:0006405 |
33 |
0.064
|
Yeast |
|
|
cardiac cell fate commitment
|
GO:0060911 |
7 |
0.064
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.063
|
Yeast |
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.063
|
Yeast |
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.062
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.062
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.062
|
Human |
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.062
|
Human Fly |
|
|
positive regulation of viral process
|
GO:0048524 |
37 |
0.061
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.061
|
|
|
|
mesoderm development
|
GO:0007498 |
14 |
0.061
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.061
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.061
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.061
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.061
|
|
|
|
rrna processing
|
GO:0006364 |
35 |
0.061
|
Yeast |
|
|
negative regulation of viral process
|
GO:0048525 |
66 |
0.060
|
|
|
|
protein localization to lysosome
|
GO:0061462 |
11 |
0.060
|
Human |
|
|
receptor internalization
|
GO:0031623 |
43 |
0.060
|
Human Fly |
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.060
|
|
|
|
endoderm development
|
GO:0007492 |
33 |
0.060
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.059
|
|
|
|
calcium ion dependent exocytosis
|
GO:0017156 |
10 |
0.059
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.059
|
Human |
|
|
autophagy
|
GO:0006914 |
88 |
0.059
|
Yeast |
|
|
negative regulation of ruffle assembly
|
GO:1900028 |
3 |
0.059
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.058
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.058
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
5 |
0.058
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.057
|
|
|
|
negative regulation of potassium ion transmembrane transporter activity
|
GO:1901017 |
3 |
0.057
|
Human |
|
|
growth
|
GO:0040007 |
202 |
0.056
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.056
|
Human |
|
|
ectodermal placode formation
|
GO:0060788 |
1 |
0.056
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.055
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.055
|
|
|
|
vacuolar transport
|
GO:0007034 |
34 |
0.054
|
Human Yeast |
|
|
endoderm formation
|
GO:0001706 |
33 |
0.053
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.053
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.052
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.052
|
|
|
|
rna transport
|
GO:0050658 |
39 |
0.052
|
Yeast |
|
|
protein monoubiquitination
|
GO:0006513 |
39 |
0.052
|
Yeast |
|
|
positive regulation of catenin import into nucleus
|
GO:0035413 |
9 |
0.052
|
|
|
|
nucleic acid transport
|
GO:0050657 |
39 |
0.052
|
Yeast |
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.051
|
|
|
|
transforming growth factor beta production
|
GO:0071604 |
14 |
0.050
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.050
|
|
|
|
lymphangiogenesis
|
GO:0001946 |
7 |
0.050
|
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
38 |
0.050
|
|
|
|
positive regulation of protein ubiquitination
|
GO:0031398 |
53 |
0.050
|
|
|
|
male sex differentiation
|
GO:0046661 |
25 |
0.050
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.050
|
Yeast |
|
|
chromatin modification
|
GO:0016568 |
298 |
0.050
|
|
|
|
ribosome localization
|
GO:0033750 |
4 |
0.050
|
Yeast |
|
|
monocarboxylic acid biosynthetic process
|
GO:0072330 |
67 |
0.049
|
Yeast |
|
|
ribonucleoprotein complex assembly
|
GO:0022618 |
78 |
0.049
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.049
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.049
|
|
|
|
negative regulation of defense response to virus
|
GO:0050687 |
10 |
0.049
|
Human |
|
|
hemostasis
|
GO:0007599 |
76 |
0.049
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.048
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.048
|
|
|
|
corticosteroid receptor signaling pathway
|
GO:0031958 |
5 |
0.048
|
Human |
|
|
negative regulation of dephosphorylation
|
GO:0035305 |
63 |
0.048
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.048
|
|
|
|
negative regulation of leukocyte activation
|
GO:0002695 |
26 |
0.047
|
|
|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
14 |
0.047
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.047
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
42 |
0.047
|
|
|
|
regulation of coagulation
|
GO:0050818 |
44 |
0.047
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.047
|
Human |
|
|
regulation of steroid metabolic process
|
GO:0019218 |
32 |
0.046
|
Yeast |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.045
|
|
|
|
regulation of gene silencing by rna
|
GO:0060966 |
6 |
0.045
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.045
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.045
|
|
