Homo sapiens

6 known processes

XAF1

XIAP associated factor 1

(Aliases: XIAPAF1,HSXIAPAF1,BIRC4BP)

XAF1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to biotic stimulus GO:0009607 276 0.963
defense response to virus GO:0051607 71 0.936
multi organism cellular process GO:0044764 156 0.919
positive regulation of rig i signaling pathway GO:1900246 4 0.895
interspecies interaction between organisms GO:0044419 156 0.836
negative regulation of viral process GO:0048525 66 0.834
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.820
viral life cycle GO:0019058 132 0.803
response to other organism GO:0051707 261 0.766
response to external biotic stimulus GO:0043207 261 0.730
defense response to other organism GO:0098542 129 0.728
regulation of viral process GO:0050792 103 0.674
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.671
response to cytokine GO:0034097 232 0.639
negative regulation of viral genome replication GO:0045071 35 0.633
immune response GO:0006955 307 0.596
defense response GO:0006952 315 0.563
regulation of multi organism process GO:0043900 157 0.549
viral genome replication GO:0019079 50 0.496
regulation of viral genome replication GO:0045069 48 0.468
response to virus GO:0009615 126 0.410
immune effector process GO:0002252 159 0.408
glycosylation GO:0070085 71 0.347
viral process GO:0016032 146 0.346
innate immune response GO:0045087 178 0.289
positive regulation of proteolysis GO:0045862 142 0.225
regulation of defense response to virus by host GO:0050691 22 0.219
regulation of intracellular transport GO:0032386 195 0.219
negative regulation of protein maturation GO:1903318 142 0.202
protein myristoylation GO:0018377 1 0.192
nucleoside phosphate biosynthetic process GO:1901293 109 0.192
negative regulation of multi organism process GO:0043901 92 0.182
regulation of nuclease activity GO:0032069 11 0.176
carbohydrate derivative biosynthetic process GO:1901137 207 0.154
regulation of defense response to virus GO:0050688 33 0.151
regulation of cytokine production GO:0001817 232 0.150
nucleotide biosynthetic process GO:0009165 109 0.147
purine nucleotide biosynthetic process GO:0006164 84 0.138
regulation of establishment of protein localization GO:0070201 242 0.126
intracellular receptor signaling pathway GO:0030522 104 0.118
regulation of immune effector process GO:0002697 91 0.118
nuclear transport GO:0051169 179 0.117
organophosphate biosynthetic process GO:0090407 163 0.114
lipoprotein biosynthetic process GO:0042158 33 0.107
organonitrogen compound biosynthetic process GO:1901566 200 0.106
negative regulation of multicellular organismal process GO:0051241 317 0.097
regulation of protein transport GO:0051223 213 0.096
protein modification by small protein conjugation GO:0032446 342 0.092
regulation of apoptotic signaling pathway GO:2001233 175 0.089
lipoprotein metabolic process GO:0042157 42 0.086
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.084
negative regulation of catalytic activity GO:0043086 335 0.083
cytokine production GO:0001816 247 0.082
cytoplasmic transport GO:0016482 379 0.082
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.081
immune response activating signal transduction GO:0002757 90 0.081
regulation of cell migration GO:0030334 289 0.081
positive regulation of cell death GO:0010942 263 0.079
positive regulation of programmed cell death GO:0043068 249 0.077
positive regulation of hydrolase activity GO:0051345 331 0.077
regulation of defense response GO:0031347 154 0.073
protein maturation GO:0051604 233 0.071
protein oligomerization GO:0051259 173 0.070
regulation of rig i signaling pathway GO:0039535 6 0.068
regulation of cytoplasmic transport GO:1903649 149 0.066
positive regulation of immune system process GO:0002684 283 0.065
regulation of immune response GO:0050776 201 0.064
positive regulation of intracellular transport GO:0032388 104 0.063
regulation of ribonuclease activity GO:0060700 3 0.063
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.063
negative regulation of protein metabolic process GO:0051248 391 0.063
macromolecule glycosylation GO:0043413 63 0.062
positive regulation of immune response GO:0050778 159 0.060
chemical homeostasis GO:0048878 306 0.060
intracellular protein transport GO:0006886 270 0.059
glycoprotein metabolic process GO:0009100 110 0.058
regulation of protein localization GO:0032880 296 0.057
response to interferon alpha GO:0035455 11 0.054
negative regulation of cellular protein metabolic process GO:0032269 353 0.054
regulation of innate immune response GO:0045088 97 0.053
positive regulation of cytokine production GO:0001819 167 0.053
nucleocytoplasmic transport GO:0006913 176 0.053
positive regulation of type i interferon production GO:0032481 20 0.051
secretion by cell GO:0032940 226 0.051
regulation of peptidase activity GO:0052547 180 0.049
protein targeting GO:0006605 187 0.048
positive regulation of phosphorylation GO:0042327 394 0.048
positive regulation of apoptotic process GO:0043065 246 0.048
i kappab kinase nf kappab signaling GO:0007249 166 0.047
regulation of nucleocytoplasmic transport GO:0046822 98 0.047
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.047
regulation of protein processing GO:0070613 150 0.045
negative regulation of apoptotic process GO:0043066 316 0.045
purine containing compound biosynthetic process GO:0072522 88 0.045
protein autoubiquitination GO:0051865 37 0.044
protein ubiquitination GO:0016567 314 0.044
negative regulation of transport GO:0051051 176 0.043
negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039532 3 0.042
response to interferon gamma GO:0034341 39 0.041
activation of immune response GO:0002253 114 0.041
positive regulation of innate immune response GO:0045089 79 0.041
multi organism metabolic process GO:0044033 41 0.040
cellular response to oxygen containing compound GO:1901701 276 0.040
negative regulation of hydrolase activity GO:0051346 182 0.039
regulation of cellular component biogenesis GO:0044087 281 0.039
transmembrane transport GO:0055085 399 0.039
regulation of dna metabolic process GO:0051052 153 0.039
regulation of angiogenesis GO:0045765 92 0.038
positive regulation of protein transport GO:0051222 135 0.038
regulation of anatomical structure morphogenesis GO:0022603 286 0.038
regulation of cysteine type endopeptidase activity GO:2000116 127 0.038
secretion GO:0046903 254 0.038
nucleoside triphosphate metabolic process GO:0009141 422 0.037
cellular response to cytokine stimulus GO:0071345 181 0.037
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.036
protein glycosylation GO:0006486 62 0.036
pattern recognition receptor signaling pathway GO:0002221 48 0.036
regulation of secretion by cell GO:1903530 177 0.036
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.036
positive regulation of multi organism process GO:0043902 56 0.036
innate immune response activating signal transduction GO:0002758 48 0.035
positive regulation of defense response GO:0031349 87 0.035
positive regulation of transport GO:0051050 336 0.035
apoptotic signaling pathway GO:0097190 268 0.035
regulation of protein secretion GO:0050708 86 0.034
response to oxygen containing compound GO:1901700 369 0.033
protein polyubiquitination GO:0000209 110 0.033
negative regulation of cell cycle GO:0045786 193 0.032
response to nitrogen compound GO:1901698 184 0.032
positive regulation of interferon alpha production GO:0032727 11 0.032
positive regulation of immune effector process GO:0002699 40 0.031
cellular response to interferon alpha GO:0035457 4 0.031
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.031
regulation of cellular component movement GO:0051270 334 0.030
regulation of proteolysis GO:0030162 293 0.030
purine nucleoside triphosphate catabolic process GO:0009146 392 0.029
purine ribonucleotide catabolic process GO:0009154 404 0.029
regulation of ion transport GO:0043269 189 0.028
cell fate determination GO:0001709 3 0.028
purine containing compound catabolic process GO:0072523 411 0.026
regulation of binding GO:0051098 111 0.026
nucleotide catabolic process GO:0009166 408 0.026
negative regulation of proteolysis GO:0045861 132 0.026
protein import into nucleus GO:0006606 104 0.025
protein secretion GO:0009306 98 0.025
negative regulation of endopeptidase activity GO:0010951 84 0.025
leukocyte differentiation GO:0002521 98 0.025
regulation of response to biotic stimulus GO:0002831 55 0.025
establishment of protein localization to organelle GO:0072594 172 0.025
glycoprotein biosynthetic process GO:0009101 91 0.025
immune response regulating signaling pathway GO:0002764 97 0.024
regulation of t helper 2 cell cytokine production GO:2000551 2 0.024
angiogenesis GO:0001525 147 0.023
rna interference GO:0016246 4 0.023
regulation of dna binding GO:0051101 37 0.023
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.023
monosaccharide metabolic process GO:0005996 74 0.023
nucleoside triphosphate catabolic process GO:0009143 394 0.023
negative regulation of immune response GO:0050777 40 0.023
regulation of cell cycle GO:0051726 393 0.023
purine nucleoside triphosphate metabolic process GO:0009144 412 0.022
positive regulation of developmental process GO:0051094 314 0.022
purine nucleotide catabolic process GO:0006195 405 0.022
positive regulation of mapk cascade GO:0043410 190 0.022
ribonucleoside triphosphate catabolic process GO:0009203 391 0.022
protein processing GO:0016485 226 0.021
cardiovascular system development GO:0072358 262 0.021
single organism cellular localization GO:1902580 332 0.021
negative regulation of vasculature development GO:1901343 43 0.021
activation of innate immune response GO:0002218 55 0.021
cellular response to lipid GO:0071396 127 0.021
biological adhesion GO:0022610 331 0.021
positive regulation of cell differentiation GO:0045597 211 0.021
leukocyte activation GO:0045321 164 0.021
vesicle mediated transport GO:0016192 371 0.021
cellular macromolecular complex assembly GO:0034622 324 0.021
glucose metabolic process GO:0006006 45 0.021
regulation of protein localization to nucleus GO:1900180 85 0.021
regulation of mapk cascade GO:0043408 262 0.020
glycosyl compound catabolic process GO:1901658 413 0.020
single organism carbohydrate metabolic process GO:0044723 193 0.020
carbohydrate metabolic process GO:0005975 207 0.020
ion transmembrane transport GO:0034220 338 0.020
negative regulation of intracellular signal transduction GO:1902532 183 0.020
response to lipid GO:0033993 206 0.020
response to dsrna GO:0043331 25 0.020
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.020
response to abiotic stimulus GO:0009628 336 0.020
regulation of metal ion transport GO:0010959 120 0.020
metal ion transport GO:0030001 272 0.020
ion homeostasis GO:0050801 230 0.020
response to exogenous dsrna GO:0043330 10 0.020
posttranscriptional regulation of gene expression GO:0010608 213 0.019
immune system development GO:0002520 195 0.019
actin filament based process GO:0030029 224 0.019
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.019
anatomical structure formation involved in morphogenesis GO:0048646 284 0.019
regulation of vasculature development GO:1901342 97 0.019
positive regulation of protein complex assembly GO:0031334 86 0.019
positive regulation of cellular component organization GO:0051130 376 0.019
protein acylation GO:0043543 138 0.019
negative regulation of blood vessel morphogenesis GO:2000181 41 0.019
regulation of lymphocyte activation GO:0051249 103 0.019
ameboidal type cell migration GO:0001667 135 0.019
negative regulation of intracellular transport of viral material GO:1901253 2 0.018
regulation of endopeptidase activity GO:0052548 170 0.018
regulation of protein maturation GO:1903317 150 0.018
cellular response to molecule of bacterial origin GO:0071219 62 0.018
regulation of response to external stimulus GO:0032101 222 0.018
purine ribonucleoside catabolic process GO:0046130 398 0.018
purine nucleoside monophosphate metabolic process GO:0009126 186 0.018
response to organic cyclic compound GO:0014070 204 0.018
response to tumor necrosis factor GO:0034612 76 0.018
protein polymerization GO:0051258 71 0.017
protein localization to organelle GO:0033365 280 0.017
rho protein signal transduction GO:0007266 26 0.017
zymogen activation GO:0031638 70 0.017
mitotic cell cycle phase transition GO:0044772 162 0.017
response to growth factor GO:0070848 205 0.017
protein localization to nucleus GO:0034504 136 0.017
activation of cysteine type endopeptidase activity GO:0097202 57 0.017
response to lipopolysaccharide GO:0032496 70 0.017
vasculature development GO:0001944 181 0.017
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.017
regulation of ion homeostasis GO:2000021 73 0.017
regulation of actin filament based process GO:0032970 141 0.017
carbohydrate homeostasis GO:0033500 31 0.016
blood vessel development GO:0001568 172 0.016
cell activation GO:0001775 213 0.016
negative regulation of cell death GO:0060548 345 0.016
regulation of purine nucleotide metabolic process GO:1900542 264 0.016
positive regulation of locomotion GO:0040017 186 0.016
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.016
regulation of intracellular transport of viral material GO:1901252 2 0.016
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.016
regulation of transferase activity GO:0051338 355 0.016
ribonucleoside catabolic process GO:0042454 406 0.016
negative regulation of peptidase activity GO:0010466 91 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.016
nucleoside phosphate catabolic process GO:1901292 412 0.016
regulation of cytoskeleton organization GO:0051493 177 0.015
organophosphate catabolic process GO:0046434 430 0.015
cellular response to endogenous stimulus GO:0071495 336 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
extrinsic apoptotic signaling pathway GO:0097191 119 0.015
cellular response to nitrogen compound GO:1901699 144 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
system process GO:0003008 349 0.015
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 24 0.015
positive regulation of apoptotic signaling pathway GO:2001235 70 0.015
regulation of kinase activity GO:0043549 314 0.015
regulation of cell adhesion GO:0030155 166 0.015
double strand break repair GO:0006302 101 0.015
positive regulation of cytoplasmic transport GO:1903651 82 0.015
anatomical structure homeostasis GO:0060249 100 0.015
negative regulation of phosphorus metabolic process GO:0010563 267 0.015
ras protein signal transduction GO:0007265 73 0.014
regulation of intracellular protein transport GO:0033157 123 0.014
regulation of protein import into nucleus GO:0042306 78 0.014
response to radiation GO:0009314 151 0.014
determination of adult lifespan GO:0008340 2 0.014
purine ribonucleoside metabolic process GO:0046128 437 0.014
negative regulation of cellular catabolic process GO:0031330 83 0.014
nucleoside monophosphate catabolic process GO:0009125 159 0.014
negative regulation of phosphate metabolic process GO:0045936 267 0.014
negative regulation of intracellular transport GO:0032387 60 0.014
single organism membrane organization GO:0044802 268 0.014
cell cycle arrest GO:0007050 71 0.014
purine nucleoside catabolic process GO:0006152 398 0.014
negative regulation of locomotion GO:0040013 118 0.014
interleukin 2 secretion GO:0070970 3 0.014
positive regulation of cellular catabolic process GO:0031331 284 0.013
atp catabolic process GO:0006200 157 0.013
cytokine mediated signaling pathway GO:0019221 109 0.013
oogenesis GO:0048477 2 0.013
cation transport GO:0006812 331 0.013
cell chemotaxis GO:0060326 112 0.013
regulation of protein complex assembly GO:0043254 147 0.013
negative regulation of nucleocytoplasmic transport GO:0046823 37 0.013
membrane organization GO:0061024 292 0.013
signal transduction by phosphorylation GO:0023014 297 0.013
negative regulation of cellular protein catabolic process GO:1903363 38 0.013
regulation of membrane potential GO:0042391 95 0.013
nucleoside monophosphate metabolic process GO:0009123 191 0.013
female gamete generation GO:0007292 2 0.013
hemopoiesis GO:0030097 180 0.012
positive regulation of cellular component biogenesis GO:0044089 158 0.012
negative regulation of protein secretion GO:0050709 29 0.012
atp metabolic process GO:0046034 176 0.012
negative regulation of endothelial cell migration GO:0010596 29 0.012
fas signaling pathway GO:0036337 3 0.012
negative regulation of protein processing GO:0010955 142 0.012
single organism nuclear import GO:1902593 104 0.012
positive regulation of interferon beta production GO:0032728 17 0.012
ribonucleotide catabolic process GO:0009261 405 0.012
regulation of secretion GO:0051046 194 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.012
nucleoside catabolic process GO:0009164 408 0.012
spermatid development GO:0007286 4 0.012
regulation of cell differentiation GO:0045595 393 0.012
positive regulation of secretion GO:0051047 116 0.012
compound eye development GO:0048749 1 0.012
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.012
cellular protein complex assembly GO:0043623 188 0.012
signal transduction by p53 class mediator GO:0072331 72 0.011
negative regulation of secretion GO:0051048 58 0.011
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.011
regulation of locomotion GO:0040012 329 0.011
positive regulation of peptidase activity GO:0010952 88 0.011
cellular homeostasis GO:0019725 196 0.011
protein localization to membrane GO:0072657 160 0.011
small gtpase mediated signal transduction GO:0007264 78 0.011
stress activated protein kinase signaling cascade GO:0031098 94 0.011
ribonucleoside triphosphate metabolic process GO:0009199 412 0.011
response to bacterium GO:0009617 144 0.011
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.011
cellular protein catabolic process GO:0044257 261 0.011
spermatid differentiation GO:0048515 4 0.011
epithelial cell migration GO:0010631 119 0.011
apoptotic mitochondrial changes GO:0008637 57 0.011
protein import GO:0017038 130 0.011
regulation of protein targeting GO:1903533 91 0.011
wnt signaling pathway GO:0016055 156 0.011
negative regulation of cytokine production GO:0001818 82 0.010
positive regulation of catabolic process GO:0009896 310 0.010
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.010
negative regulation of programmed cell death GO:0043069 321 0.010
production of molecular mediator of immune response GO:0002440 37 0.010
viral transcription GO:0019083 35 0.010
calcium ion transport GO:0006816 147 0.010
regulation of protein kinase activity GO:0045859 289 0.010
positive regulation of nucleoside metabolic process GO:0045979 186 0.010
regulation of homeostatic process GO:0032844 121 0.010
protein deubiquitination GO:0016579 79 0.010

XAF1 disease predictions

Disease DO term ID Size Probability Func Analog Org
vascular disease DOID:178 25 0.044
cardiovascular system disease DOID:1287 106 0.044
artery disease DOID:0050828 23 0.011