Homo sapiens

0 known processes

XRCC1

X-ray repair complementing defective repair in Chinese hamster cells 1

(Aliases: RCC)

XRCC1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
base excision repair GO:0006284 21 0.999
Rat
dna damage response detection of dna damage GO:0042769 3 0.990
dna repair GO:0006281 198 0.974
Mouse Rat
dna ligation involved in dna repair GO:0051103 4 0.920
cellular response to dna damage stimulus GO:0006974 379 0.872
Mouse Rat
double strand break repair GO:0006302 101 0.821
dephosphorylation GO:0016311 209 0.652
detection of stimulus GO:0051606 85 0.612
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.452
response to oxidative stress GO:0006979 121 0.350
single strand break repair GO:0000012 6 0.291
nucleotide excision repair GO:0006289 31 0.240
nucleotide phosphorylation GO:0046939 15 0.205
dna catabolic process GO:0006308 49 0.196
negative regulation of dna metabolic process GO:0051053 57 0.188
dna recombination GO:0006310 77 0.177
signal transduction involved in regulation of gene expression GO:0023019 1 0.175
cellular macromolecule catabolic process GO:0044265 380 0.171
mitochondrion organization GO:0007005 156 0.158
post embryonic development GO:0009791 2 0.156
response to oxygen containing compound GO:1901700 369 0.150
non recombinational repair GO:0000726 14 0.121
dna ligation GO:0006266 10 0.113
posttranscriptional regulation of gene expression GO:0010608 213 0.109
response to hydrogen peroxide GO:0042542 40 0.095
immunoglobulin v d j recombination GO:0033152 1 0.094
response to reactive oxygen species GO:0000302 61 0.094
single organism cellular localization GO:1902580 332 0.089
protein ubiquitination GO:0016567 314 0.081
regulation of dna metabolic process GO:0051052 153 0.080
double strand break repair via nonhomologous end joining GO:0006303 10 0.077
negative regulation of cell death GO:0060548 345 0.077
base excision repair dna ligation GO:0006288 2 0.075
response to radiation GO:0009314 151 0.074
regulation of growth rate GO:0040009 1 0.069
protein modification by small protein conjugation GO:0032446 342 0.068
response to abiotic stimulus GO:0009628 336 0.066
Rat
v d j recombination GO:0033151 3 0.060
negative regulation of apoptotic process GO:0043066 316 0.058
negative regulation of programmed cell death GO:0043069 321 0.057
protein adp ribosylation GO:0006471 9 0.055
carbohydrate metabolic process GO:0005975 207 0.053
glycoprotein biosynthetic process GO:0009101 91 0.052
cytoplasmic transport GO:0016482 379 0.052
microtubule cytoskeleton organization GO:0000226 176 0.051
enzyme linked receptor protein signaling pathway GO:0007167 303 0.050
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.050
response to inorganic substance GO:0010035 127 0.049
glycosylation GO:0070085 71 0.047
viral life cycle GO:0019058 132 0.046
dna biosynthetic process GO:0071897 40 0.046
regulation of cellular response to stress GO:0080135 244 0.045
protein import GO:0017038 130 0.045
positive regulation of transcription regulatory region dna binding GO:2000679 8 0.044
glycoprotein metabolic process GO:0009100 110 0.044
single organism nuclear import GO:1902593 104 0.043
regulation of response to dna damage stimulus GO:2001020 94 0.043
negative regulation of protein metabolic process GO:0051248 391 0.042
nucleotide catabolic process GO:0009166 408 0.041
organophosphate catabolic process GO:0046434 430 0.041
macromolecule glycosylation GO:0043413 63 0.040
regulation of protein stability GO:0031647 87 0.039
meiosis i GO:0007127 4 0.038
protein targeting GO:0006605 187 0.038
regulation of protein transport GO:0051223 213 0.038
positive regulation of protein transport GO:0051222 135 0.038
t cell differentiation in thymus GO:0033077 4 0.038
protein catabolic process GO:0030163 325 0.038
protein processing GO:0016485 226 0.037
dna replication GO:0006260 116 0.036
protein localization to organelle GO:0033365 280 0.036
response to gamma radiation GO:0010332 14 0.036
cellular response to oxygen radical GO:0071450 6 0.036
rhythmic behavior GO:0007622 2 0.035
immune response GO:0006955 307 0.035
demethylation GO:0070988 37 0.034
apoptotic signaling pathway GO:0097190 268 0.034
protein localization to nucleus GO:0034504 136 0.033
amine metabolic process GO:0009308 44 0.033
vesicle mediated transport GO:0016192 371 0.032
circulatory system development GO:0072359 262 0.032
response to growth factor GO:0070848 205 0.031
blastoderm segmentation GO:0007350 2 0.031
glycosyl compound catabolic process GO:1901658 413 0.030
regulation of dna repair GO:0006282 47 0.030
purine nucleoside triphosphate catabolic process GO:0009146 392 0.030
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.029
ribonucleoside triphosphate catabolic process GO:0009203 391 0.029
generation of neurons GO:0048699 152 0.029
epithelium development GO:0060429 227 0.029
metencephalon development GO:0022037 2 0.028
dna catabolic process exonucleolytic GO:0000738 17 0.028
response to hyperoxia GO:0055093 4 0.028
positive regulation of developmental process GO:0051094 314 0.028
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.028
negative regulation of cellular protein metabolic process GO:0032269 353 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
regulation of cellular amino acid metabolic process GO:0006521 6 0.027
system process GO:0003008 349 0.027
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.027
dna dealkylation GO:0035510 13 0.027
cell cycle g2 m phase transition GO:0044839 43 0.027
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.027
regulation of growth GO:0040008 165 0.026
protein maturation GO:0051604 233 0.026
negative regulation of phosphate metabolic process GO:0045936 267 0.026
atp metabolic process GO:0046034 176 0.026
dna demethylation GO:0080111 12 0.026
carbohydrate derivative biosynthetic process GO:1901137 207 0.026
positive regulation of cellular amine metabolic process GO:0033240 7 0.026
regulation of cell differentiation GO:0045595 393 0.026
regulation of protein localization GO:0032880 296 0.026
cellular response to ionizing radiation GO:0071479 32 0.025
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.025
protein targeting to nucleus GO:0044744 104 0.025
protein poly adp ribosylation GO:0070212 3 0.025
determination of adult lifespan GO:0008340 2 0.025
negative regulation of catalytic activity GO:0043086 335 0.025
immune effector process GO:0002252 159 0.025
nuclear import GO:0051170 106 0.025
regulation of mitotic cell cycle GO:0007346 189 0.024
negative regulation of phosphorus metabolic process GO:0010563 267 0.024
positive regulation of cell proliferation GO:0008284 301 0.024
nucleoside triphosphate metabolic process GO:0009141 422 0.024
modification dependent protein catabolic process GO:0019941 209 0.024
covalent chromatin modification GO:0016569 254 0.023
ribonucleotide catabolic process GO:0009261 405 0.023
cellular ketone metabolic process GO:0042180 80 0.023
endomembrane system organization GO:0010256 196 0.023
nucleoside catabolic process GO:0009164 408 0.023
dna strand elongation involved in dna replication GO:0006271 3 0.023
ras protein signal transduction GO:0007265 73 0.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.023
cell projection organization GO:0030030 252 0.022
response to increased oxygen levels GO:0036296 4 0.022
intracellular protein transport GO:0006886 270 0.022
regulation of multi organism process GO:0043900 157 0.022
cellular macromolecular complex assembly GO:0034622 324 0.022
single organism carbohydrate metabolic process GO:0044723 193 0.022
regulation of cellular amine metabolic process GO:0033238 11 0.022
axis elongation GO:0003401 4 0.022
regulation of anatomical structure morphogenesis GO:0022603 286 0.021
regulation of peptidase activity GO:0052547 180 0.021
regulation of cardiac muscle tissue growth GO:0055021 4 0.021
segmentation GO:0035282 4 0.021
cellular component disassembly GO:0022411 92 0.021
cell division GO:0051301 168 0.021
microtubule based process GO:0007017 210 0.021
telomere maintenance GO:0000723 32 0.021
nucleoside monophosphate catabolic process GO:0009125 159 0.021
nucleotide excision repair dna incision GO:0033683 7 0.020
nuclear transport GO:0051169 179 0.020
negative regulation of neuron apoptotic process GO:0043524 23 0.020
ion homeostasis GO:0050801 230 0.020
multi organism cellular process GO:0044764 156 0.020
regulation of cell growth GO:0001558 135 0.020
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.020
epidermis morphogenesis GO:0048730 3 0.020
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.020
negative regulation of cell proliferation GO:0008285 228 0.020
regulation of proteolysis GO:0030162 293 0.020
interspecies interaction between organisms GO:0044419 156 0.020
regulation of microtubule cytoskeleton organization GO:0070507 61 0.020
circadian behavior GO:0048512 2 0.019
regulation of keratinocyte apoptotic process GO:1902172 1 0.019
peptidyl lysine acetylation GO:0018394 101 0.019
protein acetylation GO:0006473 116 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.019
response to other organism GO:0051707 261 0.019
regulation of cell cycle process GO:0010564 266 0.019
regulation of gene expression epigenetic GO:0040029 73 0.019
cell growth GO:0016049 160 0.019
establishment of protein localization to organelle GO:0072594 172 0.019
negative regulation of cellular component organization GO:0051129 235 0.019
chemical homeostasis GO:0048878 306 0.019
microtubule organizing center organization GO:0031023 62 0.018
cerebellum development GO:0021549 2 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
protein import into nucleus GO:0006606 104 0.018
neuron apoptotic process GO:0051402 39 0.018
cilium morphogenesis GO:0060271 75 0.018
regulation of dna recombination GO:0000018 23 0.018
somitogenesis GO:0001756 2 0.018
negative regulation of reactive oxygen species metabolic process GO:2000378 11 0.018
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.018
hindbrain development GO:0030902 3 0.018
mitotic cell cycle phase transition GO:0044772 162 0.018
ribonucleoside triphosphate metabolic process GO:0009199 412 0.018
compound eye development GO:0048749 1 0.018
regulation of intracellular protein transport GO:0033157 123 0.017
positive regulation of hydrolase activity GO:0051345 331 0.017
rostrocaudal neural tube patterning GO:0021903 1 0.017
regulation of cellular ketone metabolic process GO:0010565 50 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.017
negative regulation of organelle organization GO:0010639 126 0.017
convergent extension GO:0060026 1 0.017
cellular amino acid metabolic process GO:0006520 116 0.017
regulation of viral process GO:0050792 103 0.017
response to transforming growth factor beta GO:0071559 94 0.017
positive regulation of transport GO:0051050 336 0.017
purine containing compound catabolic process GO:0072523 411 0.017
membrane organization GO:0061024 292 0.017
growth GO:0040007 202 0.017
regulation of protein kinase activity GO:0045859 289 0.017
cellular response to oxygen containing compound GO:1901701 276 0.017
negative regulation of cell cycle process GO:0010948 121 0.017
regulation of establishment of protein localization GO:0070201 242 0.016
rho protein signal transduction GO:0007266 26 0.016
cellular amine metabolic process GO:0044106 41 0.016
regulation of transferase activity GO:0051338 355 0.016
positive regulation of immune system process GO:0002684 283 0.016
developmental programmed cell death GO:0010623 3 0.016
regulation of protein import into nucleus GO:0042306 78 0.016
regulation of kinase activity GO:0043549 314 0.016
cardiovascular system development GO:0072358 262 0.016
organelle assembly GO:0070925 176 0.016
regulation of immune response GO:0050776 201 0.016
actin filament based movement GO:0030048 17 0.016
regulation of dna replication GO:0006275 68 0.015
cytokinesis GO:0000910 96 0.015
response to oxygen radical GO:0000305 6 0.015
purine nucleoside catabolic process GO:0006152 398 0.015
regulation of protein catabolic process GO:0042176 155 0.015
positive regulation of intracellular transport GO:0032388 104 0.015
cellular homeostasis GO:0019725 196 0.015
regulation of cellular component movement GO:0051270 334 0.015
cellular response to superoxide GO:0071451 6 0.015
regulation of cytoplasmic transport GO:1903649 149 0.015
histone modification GO:0016570 251 0.015
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 37 0.014
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.014
positive regulation of cellular catabolic process GO:0031331 284 0.014
cellular response to nitrogen compound GO:1901699 144 0.014
viral process GO:0016032 146 0.014
positive regulation of response to dna damage stimulus GO:2001022 43 0.014
locomotory behavior GO:0007626 1 0.014
signal transduction involved in mitotic dna integrity checkpoint GO:1902403 13 0.014
signal transduction by phosphorylation GO:0023014 297 0.014
nucleoside phosphate catabolic process GO:1901292 412 0.014
cellular response to oxidative stress GO:0034599 85 0.014
positive regulation of cell death GO:0010942 263 0.014
cellular chemical homeostasis GO:0055082 180 0.014
positive regulation of multi organism process GO:0043902 56 0.014
nucleoside triphosphate catabolic process GO:0009143 394 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.014
telomere organization GO:0032200 33 0.014
regulation of intracellular transport GO:0032386 195 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.014
anatomical structure formation involved in morphogenesis GO:0048646 284 0.014
regulation of protein localization to nucleus GO:1900180 85 0.014
positive regulation of cell differentiation GO:0045597 211 0.014
oocyte differentiation GO:0009994 2 0.014
meiotic chromosome segregation GO:0045132 4 0.013
limbic system development GO:0021761 3 0.013
Mouse
regulation of ligase activity GO:0051340 29 0.013
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.013
dna duplex unwinding GO:0032508 30 0.013
anatomical structure homeostasis GO:0060249 100 0.013
positive regulation of cytoplasmic transport GO:1903651 82 0.013
regulation of purine nucleotide catabolic process GO:0033121 205 0.013
nervous system development GO:0007399 293 0.013
Mouse
signal transduction involved in dna damage checkpoint GO:0072422 15 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.013
mitotic cell cycle GO:0000278 326 0.013
dna conformation change GO:0071103 113 0.013
negative regulation of multicellular organismal process GO:0051241 317 0.013
female gamete generation GO:0007292 2 0.013
cellular component morphogenesis GO:0032989 314 0.013
mapk cascade GO:0000165 288 0.013
meiotic chromosome separation GO:0051307 3 0.013
regulation of mitotic cell cycle phase transition GO:1901990 118 0.013
blastocyst development GO:0001824 3 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
negative regulation of transferase activity GO:0051348 124 0.013
positive regulation of intracellular protein transport GO:0090316 76 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
signal transduction involved in dna integrity checkpoint GO:0072401 15 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
cilium organization GO:0044782 68 0.012
biological adhesion GO:0022610 331 0.012
reciprocal dna recombination GO:0035825 4 0.012
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.012
cell projection morphogenesis GO:0048858 129 0.012
negative regulation of cell cycle GO:0045786 193 0.012
intra s dna damage checkpoint GO:0031573 4 0.012
morphogenesis of a polarized epithelium GO:0001738 3 0.012
regulation of protein targeting GO:1903533 91 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
oxidative stress induced premature senescence GO:0090403 3 0.012
regulation of meiotic cell cycle GO:0051445 4 0.012
chromosome segregation GO:0007059 114 0.012
rna interference GO:0016246 4 0.012
regulation of viral genome replication GO:0045069 48 0.012
positive regulation of catabolic process GO:0009896 310 0.012
guanosine containing compound catabolic process GO:1901069 239 0.012
sleep GO:0030431 2 0.012
hippocampus development GO:0021766 1 0.012
Mouse
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 41 0.012
t cell lineage commitment GO:0002360 1 0.012
oocyte development GO:0048599 1 0.012
hemopoiesis GO:0030097 180 0.012
positive regulation of protein phosphorylation GO:0001934 313 0.012
centriole replication GO:0007099 13 0.012
hematopoietic or lymphoid organ development GO:0048534 186 0.012
signal transduction involved in mitotic dna damage checkpoint GO:1902402 13 0.011
purine nucleotide catabolic process GO:0006195 405 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
positive regulation of phosphorylation GO:0042327 394 0.011
adult locomotory behavior GO:0008344 1 0.011
ribonucleoside catabolic process GO:0042454 406 0.011
epithelial cell differentiation GO:0030855 141 0.011
cell adhesion GO:0007155 325 0.011
regulation of vesicle mediated transport GO:0060627 130 0.011
negative regulation of protein modification process GO:0031400 200 0.011
regulation of mapk cascade GO:0043408 262 0.011
regeneration GO:0031099 4 0.011
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.011
negative regulation of dna replication GO:0008156 29 0.011
intracellular receptor signaling pathway GO:0030522 104 0.011
negative regulation of protein maturation GO:1903318 142 0.011
neurological system process GO:0050877 163 0.011
purine nucleoside triphosphate metabolic process GO:0009144 412 0.011
reactive oxygen species metabolic process GO:0072593 75 0.011
positive regulation of immune response GO:0050778 159 0.011
internal peptidyl lysine acetylation GO:0018393 97 0.011
establishment of planar polarity GO:0001736 3 0.011
embryo development GO:0009790 123 0.011
cellular response to organonitrogen compound GO:0071417 124 0.011
thymocyte apoptotic process GO:0070242 2 0.011
purine ribonucleoside catabolic process GO:0046130 398 0.011
cell morphogenesis GO:0000902 296 0.011
gtp metabolic process GO:0046039 239 0.011
guanosine containing compound metabolic process GO:1901068 244 0.011
pro b cell differentiation GO:0002328 1 0.011
genetic imprinting GO:0071514 1 0.011
response to organonitrogen compound GO:0010243 156 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
metal ion transport GO:0030001 272 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
cell part morphogenesis GO:0032990 137 0.011
positive regulation of proteolysis GO:0045862 142 0.011
regulation of cell cycle phase transition GO:1901987 126 0.010
positive regulation of cellular component organization GO:0051130 376 0.010
cell projection assembly GO:0030031 126 0.010
negative regulation of heart growth GO:0061117 2 0.010
single organism membrane organization GO:0044802 268 0.010
cellular protein complex assembly GO:0043623 188 0.010
positive regulation of dna metabolic process GO:0051054 73 0.010
negative regulation of stem cell proliferation GO:2000647 3 0.010
regulation of neural precursor cell proliferation GO:2000177 4 0.010
protein acylation GO:0043543 138 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.010
cellular response to endogenous stimulus GO:0071495 336 0.010
regulation of synaptic plasticity GO:0048167 3 0.010
regulation of dephosphorylation GO:0035303 96 0.010
protein glycosylation GO:0006486 62 0.010
neuroblast proliferation GO:0007405 4 0.010
cilium assembly GO:0042384 63 0.010
regulation of cell projection organization GO:0031344 107 0.010
associative learning GO:0008306 1 0.010
regulation of chromosome organization GO:0033044 103 0.010
regulation of protein processing GO:0070613 150 0.010
positive regulation of apoptotic process GO:0043065 246 0.010
regulation of neuron apoptotic process GO:0043523 35 0.010
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.010
calcium ion transport GO:0006816 147 0.010
positive regulation of cellular component movement GO:0051272 181 0.010
regulation of cell division GO:0051302 116 0.010

XRCC1 disease predictions

Disease DO term ID Size Probability Func Analog Org
epilepsy syndrome DOID:1826 41 0.998
central nervous system disease DOID:331 186 0.998
brain disease DOID:936 73 0.998
electroclinical syndrome DOID:0050701 32 0.998
neonatal period electroclinical syndrome DOID:0050702 19 0.998
nervous system disease DOID:863 431 0.998
idiopathic generalized epilepsy DOID:1827 21 0.299
ohtahara syndrome DOID:0050709 17 0.165
disease of cellular proliferation DOID:14566 174 0.108
cancer DOID:162 167 0.069
infantile epileptic encephalopathy DOID:2481 12 0.047
organ system cancer DOID:0050686 164 0.044
primary ciliary dyskinesia DOID:9562 27 0.030
gastrointestinal system cancer DOID:3119 52 0.029
musculoskeletal system disease DOID:17 223 0.021
retinal disease DOID:5679 118 0.021
sensory system disease DOID:0050155 203 0.021
eye and adnexa disease DOID:1492 150 0.021
eye disease DOID:5614 149 0.021
neurodegenerative disease DOID:1289 102 0.020
musculoskeletal system cancer DOID:0060100 11 0.014
connective tissue disease DOID:65 109 0.013
breast cancer DOID:1612 21 0.012
thoracic cancer DOID:5093 21 0.012
cardiovascular system disease DOID:1287 106 0.012
myopathy DOID:423 104 0.012
muscular disease DOID:0080000 114 0.012
muscle tissue disease DOID:66 113 0.012
disease of metabolism DOID:0014667 295 0.011
retinal degeneration DOID:8466 89 0.011