Homo sapiens

45 known processes

XRCC4

X-ray repair complementing defective repair in Chinese hamster cells 4

XRCC4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna ligation involved in dna repair GO:0051103 4 1.000
single strand break repair GO:0000012 6 0.990
dna ligation GO:0006266 10 0.989
double strand break repair GO:0006302 101 0.979
dna repair GO:0006281 198 0.948
double strand break repair via nonhomologous end joining GO:0006303 10 0.831
nucleotide excision repair GO:0006289 31 0.725
cellular response to dna damage stimulus GO:0006974 379 0.690
non recombinational repair GO:0000726 14 0.650
v d j recombination GO:0033151 3 0.624
Mouse
response to ionizing radiation GO:0010212 65 0.456
t cell activation GO:0042110 99 0.418
Mouse
negative regulation of cell death GO:0060548 345 0.409
Mouse
t cell differentiation in thymus GO:0033077 4 0.373
Mouse
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.358
Mouse
somatic stem cell maintenance GO:0035019 4 0.347
dna damage response detection of dna damage GO:0042769 3 0.344
fibroblast proliferation GO:0048144 33 0.334
Mouse
negative regulation of apoptotic process GO:0043066 316 0.314
Mouse
regulation of cell differentiation GO:0045595 393 0.295
Mouse
response to gamma radiation GO:0010332 14 0.261
Mouse
response to abiotic stimulus GO:0009628 336 0.260
positive regulation of cell proliferation GO:0008284 301 0.259
Mouse
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.253
lymphocyte differentiation GO:0030098 35 0.250
Mouse
b cell activation GO:0042113 33 0.248
Mouse
positive regulation of nervous system development GO:0051962 54 0.238
Mouse
pro b cell differentiation GO:0002328 1 0.226
Mouse
negative regulation of cell differentiation GO:0045596 171 0.219
positive regulation of cell development GO:0010720 92 0.199
Mouse
response to radiation GO:0009314 151 0.196
stem cell differentiation GO:0048863 93 0.189
positive regulation of developmental process GO:0051094 314 0.177
Mouse
hematopoietic progenitor cell differentiation GO:0002244 38 0.173
Mouse
negative regulation of neuron apoptotic process GO:0043524 23 0.168
Mouse
cellular macromolecule catabolic process GO:0044265 380 0.162
lymphocyte mediated immunity GO:0002449 48 0.154
Mouse
dephosphorylation GO:0016311 209 0.146
cell aging GO:0007569 52 0.136
dna catabolic process GO:0006308 49 0.128
lymphocyte activation GO:0046649 133 0.122
Mouse
leukocyte differentiation GO:0002521 98 0.122
Mouse
positive regulation of neurogenesis GO:0050769 49 0.119
Mouse
dna catabolic process endonucleolytic GO:0000737 37 0.113
cell activation GO:0001775 213 0.109
Mouse
leukocyte activation GO:0045321 164 0.097
Mouse
regulation of nervous system development GO:0051960 88 0.093
Mouse
dna recombination GO:0006310 77 0.088
Mouse
negative regulation of programmed cell death GO:0043069 321 0.086
Mouse
leukocyte mediated immunity GO:0002443 59 0.084
Mouse
regulation of fibroblast proliferation GO:0048145 32 0.083
Mouse
isotype switching GO:0045190 3 0.078
Mouse
post embryonic development GO:0009791 2 0.076
replicative cell aging GO:0001302 3 0.072
regulation of dna metabolic process GO:0051052 153 0.069
negative regulation of organelle organization GO:0010639 126 0.067
dna catabolic process exonucleolytic GO:0000738 17 0.063
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 3 0.058
Mouse
response to reactive oxygen species GO:0000302 61 0.056
double strand break repair via homologous recombination GO:0000724 50 0.056
positive regulation of cell differentiation GO:0045597 211 0.056
Mouse
regulation of cell cycle process GO:0010564 266 0.055
positive regulation of transferase activity GO:0051347 227 0.053
meiosis i GO:0007127 4 0.053
leukocyte activation involved in immune response GO:0002366 30 0.048
Mouse
recombinational repair GO:0000725 50 0.045
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.043
Mouse
cell activation involved in immune response GO:0002263 30 0.039
Mouse
organelle assembly GO:0070925 176 0.039
generation of neurons GO:0048699 152 0.038
Mouse
regulation of meiosis GO:0040020 3 0.037
response to oxidative stress GO:0006979 121 0.037
cytokinesis GO:0000910 96 0.036
positive regulation of kinase activity GO:0033674 204 0.035
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.035
Mouse
regulation of neuron apoptotic process GO:0043523 35 0.034
Mouse
regulation of cell development GO:0060284 161 0.033
Mouse
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 5 0.033
Mouse
cell division GO:0051301 168 0.033
hematopoietic or lymphoid organ development GO:0048534 186 0.033
Mouse
regulation of ras protein signal transduction GO:0046578 155 0.032
somatic diversification of immune receptors GO:0002200 8 0.032
Mouse
embryo development ending in birth or egg hatching GO:0009792 34 0.029
Mouse
female gamete generation GO:0007292 2 0.029
positive regulation of protein phosphorylation GO:0001934 313 0.028
amine metabolic process GO:0009308 44 0.028
regulation of growth GO:0040008 165 0.028
regulation of meiotic cell cycle GO:0051445 4 0.027
regulation of small gtpase mediated signal transduction GO:0051056 156 0.026
microtubule cytoskeleton organization GO:0000226 176 0.025
microtubule polymerization or depolymerization GO:0031109 37 0.025
regulation of protein transport GO:0051223 213 0.025
regulation of nuclear division GO:0051783 65 0.024
regulation of anatomical structure morphogenesis GO:0022603 286 0.024
telomere organization GO:0032200 33 0.023
positive regulation of cellular catabolic process GO:0031331 284 0.023
rho protein signal transduction GO:0007266 26 0.022
chromosome segregation GO:0007059 114 0.021
immunoglobulin production GO:0002377 12 0.021
Mouse
regulation of transferase activity GO:0051338 355 0.021
single organism cellular localization GO:1902580 332 0.021
regulation of cell division GO:0051302 116 0.021
regulation of protein kinase activity GO:0045859 289 0.021
centrosome cycle GO:0007098 32 0.020
ras protein signal transduction GO:0007265 73 0.020
organelle fission GO:0048285 149 0.020
positive regulation of ras gtpase activity GO:0032320 117 0.020
rna processing GO:0006396 255 0.019
production of molecular mediator of immune response GO:0002440 37 0.019
Mouse
mitotic cell cycle process GO:1903047 286 0.018
mrna metabolic process GO:0016071 175 0.018
cell projection assembly GO:0030031 126 0.018
negative regulation of cellular component organization GO:0051129 235 0.018
meiotic chromosome segregation GO:0045132 4 0.017
single organism carbohydrate metabolic process GO:0044723 193 0.017
viral life cycle GO:0019058 132 0.017
enzyme linked receptor protein signaling pathway GO:0007167 303 0.016
nucleoside triphosphate catabolic process GO:0009143 394 0.016
regulation of nucleoside metabolic process GO:0009118 209 0.016
cell growth GO:0016049 160 0.016
regulation of kinase activity GO:0043549 314 0.016
positive regulation of dna metabolic process GO:0051054 73 0.016
response to inorganic substance GO:0010035 127 0.016
protein targeting GO:0006605 187 0.016
regulation of purine nucleotide catabolic process GO:0033121 205 0.015
hippocampus development GO:0021766 1 0.015
vasculature development GO:0001944 181 0.015
somatic cell dna recombination GO:0016444 6 0.015
Mouse
stem cell maintenance GO:0019827 19 0.015
regulation of cellular amine metabolic process GO:0033238 11 0.015
regulation of cell morphogenesis GO:0022604 153 0.015
actin filament based process GO:0030029 224 0.015
regulation of cell cycle phase transition GO:1901987 126 0.015
lipid metabolic process GO:0006629 381 0.015
central nervous system development GO:0007417 123 0.015
Mouse
positive regulation of gtp catabolic process GO:0033126 166 0.015
regulation of binding GO:0051098 111 0.014
negative regulation of catalytic activity GO:0043086 335 0.014
purine nucleoside triphosphate catabolic process GO:0009146 392 0.014
regulation of cell cycle GO:0051726 393 0.014
lipid biosynthetic process GO:0008610 177 0.014
organophosphate catabolic process GO:0046434 430 0.014
regulation of establishment of protein localization GO:0070201 242 0.014
regulation of protein localization GO:0032880 296 0.013
vesicle mediated transport GO:0016192 371 0.013
nucleotide catabolic process GO:0009166 408 0.013
regulation of mitotic cell cycle phase transition GO:1901990 118 0.013
peptidyl serine phosphorylation GO:0018105 101 0.013
lymphocyte activation involved in immune response GO:0002285 20 0.013
Mouse
negative regulation of protein metabolic process GO:0051248 391 0.013
erk1 and erk2 cascade GO:0070371 104 0.013
protein maturation GO:0051604 233 0.013
regulation of cellular amino acid metabolic process GO:0006521 6 0.013
intracellular protein transport GO:0006886 270 0.013
response to decreased oxygen levels GO:0036293 96 0.013
regulation of cellular response to stress GO:0080135 244 0.013
positive regulation of hydrolase activity GO:0051345 331 0.012
regulation of ras gtpase activity GO:0032318 128 0.012
actin cytoskeleton organization GO:0030036 207 0.012
regulation of purine nucleotide metabolic process GO:1900542 264 0.012
positive regulation of phosphorylation GO:0042327 394 0.012
mitotic nuclear division GO:0007067 119 0.012
glycosyl compound catabolic process GO:1901658 413 0.012
regulation of nucleotide metabolic process GO:0006140 269 0.012
telomere maintenance GO:0000723 32 0.012
nucleoside catabolic process GO:0009164 408 0.012
purine nucleotide catabolic process GO:0006195 405 0.012
microtubule based process GO:0007017 210 0.012
positive regulation of cell cycle process GO:0090068 106 0.012
multi organism cellular process GO:0044764 156 0.011
positive regulation of cellular component organization GO:0051130 376 0.011
mrna processing GO:0006397 133 0.011
head development GO:0060322 108 0.011
regulation of cell projection organization GO:0031344 107 0.011
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.011
regulation of dna recombination GO:0000018 23 0.011
mapk cascade GO:0000165 288 0.011
positive regulation of intracellular protein transport GO:0090316 76 0.011
cytoplasmic transport GO:0016482 379 0.011
regulation of cytoskeleton organization GO:0051493 177 0.011
cardiovascular system development GO:0072358 262 0.011
regulation of proteolysis GO:0030162 293 0.011
regulation of cell growth GO:0001558 135 0.011
maintenance of location GO:0051235 112 0.011
posttranscriptional regulation of gene expression GO:0010608 213 0.011
carbohydrate metabolic process GO:0005975 207 0.011
cilium morphogenesis GO:0060271 75 0.011
neuron apoptotic process GO:0051402 39 0.011
Mouse
negative regulation of dna metabolic process GO:0051053 57 0.011
establishment of organelle localization GO:0051656 59 0.010
regulation of gtpase activity GO:0043087 180 0.010
dna replication GO:0006260 116 0.010
regulation of response to dna damage stimulus GO:2001020 94 0.010
regulation of intracellular transport GO:0032386 195 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.010
regulation of membrane potential GO:0042391 95 0.010
positive regulation of proteolysis GO:0045862 142 0.010
guanosine containing compound catabolic process GO:1901069 239 0.010
negative regulation of phosphorus metabolic process GO:0010563 267 0.010
cellular macromolecular complex assembly GO:0034622 324 0.010
positive regulation of cell cycle GO:0045787 140 0.010
response to wounding GO:0009611 168 0.010
positive regulation of nucleotide catabolic process GO:0030813 185 0.010

XRCC4 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.737
disease of cellular proliferation DOID:14566 174 0.285
electroclinical syndrome DOID:0050701 32 0.266
central nervous system disease DOID:331 186 0.266
brain disease DOID:936 73 0.266
neonatal period electroclinical syndrome DOID:0050702 19 0.266
nervous system disease DOID:863 431 0.266
epilepsy syndrome DOID:1826 41 0.266
cancer DOID:162 167 0.203
organ system cancer DOID:0050686 164 0.203
primary immunodeficiency disease DOID:612 36 0.151
combined t cell and b cell immunodeficiency DOID:628 12 0.151
hematologic cancer DOID:2531 36 0.075
immune system cancer DOID:0060083 36 0.075
myeloma DOID:0070004 7 0.059
bone marrow cancer DOID:4960 10 0.059
idiopathic generalized epilepsy DOID:1827 21 0.028
ohtahara syndrome DOID:0050709 17 0.018
sensory system disease DOID:0050155 203 0.012