Homo sapiens

42 known processes

XRN2

5'-3' exoribonuclease 2

XRN2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna processing GO:0006396 255 0.455
Worm
ncrna metabolic process GO:0034660 108 0.283
Worm
trna processing GO:0008033 23 0.256
purine containing compound catabolic process GO:0072523 411 0.244
intracellular mrna localization GO:0008298 1 0.243
purine nucleotide catabolic process GO:0006195 405 0.208
post embryonic development GO:0009791 2 0.204
Worm
viral process GO:0016032 146 0.148
oogenesis GO:0048477 2 0.141
nucleoside phosphate catabolic process GO:1901292 412 0.123
ribonucleoside catabolic process GO:0042454 406 0.123
multicellular organismal aging GO:0010259 3 0.108
gtp metabolic process GO:0046039 239 0.105
cellular component disassembly GO:0022411 92 0.104
organophosphate catabolic process GO:0046434 430 0.100
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.099
blastoderm segmentation GO:0007350 2 0.098
single organism cellular localization GO:1902580 332 0.097
nucleoside triphosphate catabolic process GO:0009143 394 0.096
immune response GO:0006955 307 0.093
ncrna processing GO:0034470 83 0.092
nuclear transport GO:0051169 179 0.090
glycosyl compound catabolic process GO:1901658 413 0.088
rna 3 end processing GO:0031123 35 0.088
ribonucleoprotein complex subunit organization GO:0071826 81 0.088
determination of adult lifespan GO:0008340 2 0.088
interspecies interaction between organisms GO:0044419 156 0.084
purine ribonucleotide catabolic process GO:0009154 404 0.084
membrane organization GO:0061024 292 0.083
gtp catabolic process GO:0006184 237 0.079
regulation of intracellular transport GO:0032386 195 0.074
mitotic cell cycle GO:0000278 326 0.072
guanosine containing compound metabolic process GO:1901068 244 0.067
purine nucleoside catabolic process GO:0006152 398 0.067
ribonucleoside triphosphate metabolic process GO:0009199 412 0.067
intracellular protein transport GO:0006886 270 0.065
cytoplasmic transport GO:0016482 379 0.065
small gtpase mediated signal transduction GO:0007264 78 0.061
rna localization GO:0006403 41 0.059
viral life cycle GO:0019058 132 0.059
organophosphate biosynthetic process GO:0090407 163 0.052
positive regulation of cellular component organization GO:0051130 376 0.050
nucleoside catabolic process GO:0009164 408 0.050
female gamete generation GO:0007292 2 0.050
regulation of cell cycle process GO:0010564 266 0.048
multi organism cellular process GO:0044764 156 0.048
mitotic cell cycle process GO:1903047 286 0.045
regulation of gtp catabolic process GO:0033124 180 0.044
purine ribonucleoside catabolic process GO:0046130 398 0.044
rna transport GO:0050658 39 0.041
ribonucleotide catabolic process GO:0009261 405 0.041
locomotory behavior GO:0007626 1 0.041
segmentation GO:0035282 4 0.041
nuclear export GO:0051168 69 0.039
nucleoside triphosphate metabolic process GO:0009141 422 0.039
coenzyme metabolic process GO:0006732 65 0.039
organelle assembly GO:0070925 176 0.037
positive regulation of catabolic process GO:0009896 310 0.037
vesicle mediated transport GO:0016192 371 0.037
negative regulation of multi organism process GO:0043901 92 0.037
tripartite regional subdivision GO:0007351 2 0.037
purine ribonucleoside metabolic process GO:0046128 437 0.036
cell morphogenesis GO:0000902 296 0.036
regulation of binding GO:0051098 111 0.035
oocyte development GO:0048599 1 0.035
mrna export from nucleus GO:0006406 29 0.035
mrna 3 end processing GO:0031124 24 0.035
positive regulation of cellular catabolic process GO:0031331 284 0.035
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.035
nervous system development GO:0007399 293 0.035
system process GO:0003008 349 0.034
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.034
regulation of ras protein signal transduction GO:0046578 155 0.034
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.034
anterior posterior axis specification embryo GO:0008595 2 0.034
regulation of nucleotide metabolic process GO:0006140 269 0.033
rna modification GO:0009451 27 0.033
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.033
ribonucleoprotein complex assembly GO:0022618 78 0.033
mrna metabolic process GO:0016071 175 0.033
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.032
negative regulation of cell death GO:0060548 345 0.032
guanosine containing compound catabolic process GO:1901069 239 0.032
cellular macromolecule catabolic process GO:0044265 380 0.032
regulation of small gtpase mediated signal transduction GO:0051056 156 0.031
purine nucleoside triphosphate metabolic process GO:0009144 412 0.031
regulation of viral process GO:0050792 103 0.031
negative regulation of viral process GO:0048525 66 0.031
cofactor metabolic process GO:0051186 87 0.031
nuclear import GO:0051170 106 0.030
regulation of rab protein signal transduction GO:0032483 39 0.030
positive regulation of intracellular transport GO:0032388 104 0.030
regulation of anatomical structure morphogenesis GO:0022603 286 0.030
regulation of meiotic cell cycle GO:0051445 4 0.029
rab protein signal transduction GO:0032482 4 0.029
regulation of purine nucleotide catabolic process GO:0033121 205 0.029
mrna transport GO:0051028 30 0.029
purine nucleoside monophosphate catabolic process GO:0009128 158 0.029
purine nucleoside triphosphate catabolic process GO:0009146 392 0.029
innate immune response GO:0045087 178 0.028
cellular macromolecular complex assembly GO:0034622 324 0.028
positive regulation of hydrolase activity GO:0051345 331 0.028
lipid metabolic process GO:0006629 381 0.028
defense response GO:0006952 315 0.028
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.028
negative regulation of developmental process GO:0051093 247 0.027
cation homeostasis GO:0055080 189 0.027
oocyte differentiation GO:0009994 2 0.026
mrna processing GO:0006397 133 0.026
positive regulation of apoptotic process GO:0043065 246 0.025
regulation of nucleotide catabolic process GO:0030811 205 0.025
anterior posterior axis specification GO:0009948 2 0.025
actin filament based process GO:0030029 224 0.025
regulation of establishment of protein localization GO:0070201 242 0.025
protein import GO:0017038 130 0.024
rna export from nucleus GO:0006405 33 0.024
regulation of multi organism process GO:0043900 157 0.024
ras protein signal transduction GO:0007265 73 0.024
negative regulation of multicellular organismal process GO:0051241 317 0.024
regulation of protein catabolic process GO:0042176 155 0.024
regulation of nucleoside metabolic process GO:0009118 209 0.024
positive regulation of gtp catabolic process GO:0033126 166 0.023
establishment of protein localization to membrane GO:0090150 121 0.023
regulation of protein transport GO:0051223 213 0.023
nucleotide catabolic process GO:0009166 408 0.023
cell growth GO:0016049 160 0.023
negative regulation of phosphorus metabolic process GO:0010563 267 0.023
regulation of cytoplasmic transport GO:1903649 149 0.022
cellular component morphogenesis GO:0032989 314 0.022
protein targeting to nucleus GO:0044744 104 0.022
neuron projection development GO:0031175 106 0.022
protein localization to nucleus GO:0034504 136 0.022
establishment of rna localization GO:0051236 39 0.022
cell part morphogenesis GO:0032990 137 0.022
organelle localization GO:0051640 84 0.022
regulation of cellular amino acid metabolic process GO:0006521 6 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.021
regulation of gtpase activity GO:0043087 180 0.021
rna splicing GO:0008380 131 0.021
regulation of meiosis GO:0040020 3 0.021
protein catabolic process GO:0030163 325 0.021
snrna metabolic process GO:0016073 15 0.021
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.021
nucleocytoplasmic transport GO:0006913 176 0.021
nuclear transcribed mrna catabolic process GO:0000956 48 0.021
regulation of protein targeting GO:1903533 91 0.020
negative regulation of intracellular signal transduction GO:1902532 183 0.020
regulation of apoptotic signaling pathway GO:2001233 175 0.020
aging GO:0007568 66 0.020
cellular amine metabolic process GO:0044106 41 0.020
hematopoietic or lymphoid organ development GO:0048534 186 0.020
amine metabolic process GO:0009308 44 0.020
immune effector process GO:0002252 159 0.019
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.019
cell cycle phase transition GO:0044770 173 0.019
engulfment of apoptotic cell GO:0043652 2 0.019
negative regulation of catalytic activity GO:0043086 335 0.019
regulation of cell cycle g1 s phase transition GO:1902806 42 0.019
histone mrna metabolic process GO:0008334 13 0.019
regulation of cellular response to stress GO:0080135 244 0.019
positive regulation of protein catabolic process GO:0045732 75 0.019
rna catabolic process GO:0006401 71 0.019
Worm
cell morphogenesis involved in differentiation GO:0000904 144 0.019
regulation of cell cycle GO:0051726 393 0.018
response to wounding GO:0009611 168 0.018
single organism cell adhesion GO:0098602 179 0.018
rna interference GO:0016246 4 0.018
cell projection organization GO:0030030 252 0.018
positive regulation of protein transport GO:0051222 135 0.018
regulation of cellular component biogenesis GO:0044087 281 0.018
mrna catabolic process GO:0006402 56 0.018
growth GO:0040007 202 0.018
dna geometric change GO:0032392 32 0.018
positive regulation of apoptotic signaling pathway GO:2001235 70 0.017
nitrogen compound transport GO:0071705 191 0.017
positive regulation of cell cycle process GO:0090068 106 0.017
organonitrogen compound biosynthetic process GO:1901566 200 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
Worm
protein localization to organelle GO:0033365 280 0.017
adult locomotory behavior GO:0008344 1 0.017
response to biotic stimulus GO:0009607 276 0.017
ribonucleoside triphosphate catabolic process GO:0009203 391 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
cytokine production GO:0001816 247 0.017
protein modification by small protein removal GO:0070646 92 0.017
translation GO:0006412 132 0.017
lipid localization GO:0010876 106 0.017
cation transport GO:0006812 331 0.016
ribonucleoprotein complex biogenesis GO:0022613 116 0.016
regulation of immune response GO:0050776 201 0.016
positive regulation of intracellular protein transport GO:0090316 76 0.016
regulation of nucleocytoplasmic transport GO:0046822 98 0.016
single organism nuclear import GO:1902593 104 0.016
negative regulation of cellular component organization GO:0051129 235 0.016
multicellular organismal signaling GO:0035637 34 0.016
apoptotic signaling pathway GO:0097190 268 0.016
translational initiation GO:0006413 48 0.016
cell projection morphogenesis GO:0048858 129 0.016
negative regulation of apoptotic process GO:0043066 316 0.015
response to nitrogen compound GO:1901698 184 0.015
actin cytoskeleton organization GO:0030036 207 0.015
regulation of cellular amine metabolic process GO:0033238 11 0.015
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 23 0.015
cell development GO:0048468 328 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
positive regulation of transport GO:0051050 336 0.015
protein targeting GO:0006605 187 0.015
biological adhesion GO:0022610 331 0.015
positive regulation of cytoplasmic transport GO:1903651 82 0.015
sleep GO:0030431 2 0.015
cofactor biosynthetic process GO:0051188 31 0.015
ncrna 3 end processing GO:0043628 4 0.014
ribonucleoside monophosphate metabolic process GO:0009161 187 0.014
blastocyst development GO:0001824 3 0.014
negative regulation of programmed cell death GO:0043069 321 0.014
dna replication GO:0006260 116 0.014
negative regulation of growth GO:0045926 97 0.014
microtubule based process GO:0007017 210 0.014
cardiovascular system development GO:0072358 262 0.014
cellular response to cytokine stimulus GO:0071345 181 0.014
coenzyme biosynthetic process GO:0009108 24 0.014
positive regulation of ras gtpase activity GO:0032320 117 0.014
neurological system process GO:0050877 163 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
wound healing GO:0042060 115 0.014
nucleobase containing compound transport GO:0015931 51 0.014
establishment of protein localization to organelle GO:0072594 172 0.014
regeneration GO:0031099 4 0.014
regulation of ras gtpase activity GO:0032318 128 0.013
blood vessel development GO:0001568 172 0.013
metal ion homeostasis GO:0055065 169 0.013
blood vessel morphogenesis GO:0048514 162 0.013
negative regulation of mitotic cell cycle GO:0045930 102 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.013
regulation of gene expression epigenetic GO:0040029 73 0.013
Worm
cellular homeostasis GO:0019725 196 0.013
meiosis i GO:0007127 4 0.013
generation of neurons GO:0048699 152 0.013
neuron development GO:0048666 113 0.013
regulation of cytokine production GO:0001817 232 0.013
regulation of translation GO:0006417 89 0.013
methylation GO:0032259 106 0.013
regulation of protein localization GO:0032880 296 0.013
trna metabolic process GO:0006399 35 0.012
regulation of cellular ketone metabolic process GO:0010565 50 0.012
immune system development GO:0002520 195 0.012
regulation of cell division GO:0051302 116 0.012
rna polyadenylation GO:0043631 14 0.012
cellular cation homeostasis GO:0030003 163 0.012
positive regulation of protein complex assembly GO:0031334 86 0.012
response to cytokine GO:0034097 232 0.012
cell cycle g1 s phase transition GO:0044843 80 0.012
regulation of membrane potential GO:0042391 95 0.012
cellular response to dna damage stimulus GO:0006974 379 0.012
regulation of growth GO:0040008 165 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
positive regulation of cell death GO:0010942 263 0.012
vasculature development GO:0001944 181 0.012
response to extracellular stimulus GO:0009991 85 0.012
wnt signaling pathway GO:0016055 156 0.012
ribonucleoprotein complex disassembly GO:0032988 7 0.012
positive regulation of immune system process GO:0002684 283 0.012
neuron differentiation GO:0030182 138 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.012
melanin metabolic process GO:0006582 1 0.012
nucleoside monophosphate catabolic process GO:0009125 159 0.012
g1 s transition of mitotic cell cycle GO:0000082 78 0.012
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.012
regulation of vasculature development GO:1901342 97 0.012
cation transmembrane transport GO:0098655 238 0.012
tissue regeneration GO:0042246 3 0.011
microtubule cytoskeleton organization GO:0000226 176 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.011
inorganic cation transmembrane transport GO:0098662 194 0.011
mating GO:0007618 1 0.011
motor neuron axon guidance GO:0008045 2 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
neurogenesis GO:0022008 169 0.011
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
cell adhesion GO:0007155 325 0.011
regulation of cell cycle phase transition GO:1901987 126 0.011
multicellular organismal reproductive process GO:0048609 40 0.011
positive regulation of mitotic cell cycle GO:0045931 60 0.011
multi organism metabolic process GO:0044033 41 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
regulation of body fluid levels GO:0050878 99 0.011
regulation of mitotic cell cycle GO:0007346 189 0.010
endomembrane system organization GO:0010256 196 0.010
positive regulation of organelle organization GO:0010638 195 0.010
single organism membrane organization GO:0044802 268 0.010
rho protein signal transduction GO:0007266 26 0.010
circulatory system development GO:0072359 262 0.010
dosage compensation GO:0007549 3 0.010
cellular metal ion homeostasis GO:0006875 146 0.010
positive regulation of developmental process GO:0051094 314 0.010

XRN2 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.063
sensory system disease DOID:0050155 203 0.027
nervous system disease DOID:863 431 0.027
eye and adnexa disease DOID:1492 150 0.021
disease of mental health DOID:150 70 0.020
central nervous system disease DOID:331 186 0.017
brain disease DOID:936 73 0.014
skin disease DOID:37 33 0.012
integumentary system disease DOID:16 43 0.012
neurodegenerative disease DOID:1289 102 0.010