Homo sapiens

7 known processes

YARS

tyrosyl-tRNA synthetase

(Aliases: TYRRS,CMTDIC,YRS,YTS)

YARS biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
trna aminoacylation for protein translation GO:0006418 8 1.000
amino acid activation GO:0043038 12 0.998
alpha amino acid metabolic process GO:1901605 72 0.976
mitochondrial rna metabolic process GO:0000959 15 0.931
trna aminoacylation GO:0043039 12 0.931
cellular amino acid metabolic process GO:0006520 116 0.926
trna metabolic process GO:0006399 35 0.786
one carbon metabolic process GO:0006730 1 0.652
ncrna metabolic process GO:0034660 108 0.601
translation GO:0006412 132 0.600
coenzyme metabolic process GO:0006732 65 0.584
organophosphate biosynthetic process GO:0090407 163 0.433
serine family amino acid metabolic process GO:0009069 12 0.431
cellular amino acid catabolic process GO:0009063 31 0.394
alpha amino acid catabolic process GO:1901606 26 0.369
post embryonic development GO:0009791 2 0.308
water soluble vitamin metabolic process GO:0006767 6 0.307
cellular modified amino acid metabolic process GO:0006575 64 0.259
organonitrogen compound biosynthetic process GO:1901566 200 0.210
l serine metabolic process GO:0006563 5 0.177
proline transport GO:0015824 4 0.175
trna aminoacylation for mitochondrial protein translation GO:0070127 3 0.168
l alanine transport GO:0015808 3 0.168
purine nucleobase biosynthetic process GO:0009113 3 0.144
multicellular organismal aging GO:0010259 3 0.141
cell type specific apoptotic process GO:0097285 125 0.140
organic anion transport GO:0015711 103 0.131
small molecule biosynthetic process GO:0044283 157 0.129
nucleobase biosynthetic process GO:0046112 4 0.122
alpha amino acid biosynthetic process GO:1901607 23 0.115
oogenesis GO:0048477 2 0.105
female gamete generation GO:0007292 2 0.099
chloride transmembrane transport GO:1902476 38 0.092
endocytosis GO:0006897 159 0.091
rna processing GO:0006396 255 0.089
regulation of translation GO:0006417 89 0.088
cellular response to endogenous stimulus GO:0071495 336 0.088
response to nitrogen compound GO:1901698 184 0.081
patterning of blood vessels GO:0001569 2 0.079
alanine transport GO:0032328 3 0.076
folic acid containing compound metabolic process GO:0006760 6 0.073
regulation of neuron death GO:1901214 56 0.069
serine family amino acid catabolic process GO:0009071 5 0.067
cellular macromolecule catabolic process GO:0044265 380 0.064
nucleoside phosphate biosynthetic process GO:1901293 109 0.063
pigment biosynthetic process GO:0046148 10 0.060
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.058
vesicle mediated transport GO:0016192 371 0.057
mitochondrion organization GO:0007005 156 0.055
dna templated transcription termination GO:0006353 3 0.054
metencephalon development GO:0022037 2 0.049
cellular amino acid biosynthetic process GO:0008652 30 0.046
angiogenesis GO:0001525 147 0.045
chemical homeostasis GO:0048878 306 0.044
negative regulation of apoptotic process GO:0043066 316 0.044
cofactor metabolic process GO:0051186 87 0.043
nucleotide biosynthetic process GO:0009165 109 0.043
regulation of mitotic cell cycle GO:0007346 189 0.042
lipid metabolic process GO:0006629 381 0.040
negative regulation of phosphate metabolic process GO:0045936 267 0.039
transmembrane transport GO:0055085 399 0.038
toxin transport GO:1901998 4 0.035
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.035
purine containing compound biosynthetic process GO:0072522 88 0.035
positive regulation of cellular catabolic process GO:0031331 284 0.034
purine nucleobase metabolic process GO:0006144 5 0.034
embryo development GO:0009790 123 0.034
Worm
organic acid biosynthetic process GO:0016053 97 0.033
determination of adult lifespan GO:0008340 2 0.033
negative regulation of catalytic activity GO:0043086 335 0.033
amine metabolic process GO:0009308 44 0.033
hindbrain development GO:0030902 3 0.031
regulation of locomotion GO:0040012 329 0.030
head development GO:0060322 108 0.030
regulation of cellular amine metabolic process GO:0033238 11 0.030
glutamate metabolic process GO:0006536 10 0.029
hexose metabolic process GO:0019318 55 0.029
carbohydrate metabolic process GO:0005975 207 0.029
small molecule catabolic process GO:0044282 92 0.029
carboxylic acid biosynthetic process GO:0046394 97 0.029
circulatory system development GO:0072359 262 0.027
dicarboxylic acid metabolic process GO:0043648 29 0.027
sulfur amino acid transport GO:0000101 2 0.027
positive regulation of catabolic process GO:0009896 310 0.026
regulation of anatomical structure morphogenesis GO:0022603 286 0.026
anatomical structure formation involved in morphogenesis GO:0048646 284 0.026
negative regulation of cell migration GO:0030336 102 0.026
maintenance of location GO:0051235 112 0.026
modified amino acid transport GO:0072337 11 0.025
response to amino acid GO:0043200 14 0.025
negative regulation of hydrolase activity GO:0051346 182 0.025
cation transmembrane transport GO:0098655 238 0.025
response to peptide hormone GO:0043434 61 0.025
positive regulation of hydrolase activity GO:0051345 331 0.025
organic acid transport GO:0015849 65 0.024
nervous system development GO:0007399 293 0.024
system process GO:0003008 349 0.023
positive regulation of cellular amine metabolic process GO:0033240 7 0.023
glycoprotein metabolic process GO:0009100 110 0.023
anion transport GO:0006820 161 0.023
rna splicing GO:0008380 131 0.023
negative regulation of cell differentiation GO:0045596 171 0.023
protein folding GO:0006457 38 0.023
blood vessel development GO:0001568 172 0.022
regulation of cellular component movement GO:0051270 334 0.022
inorganic ion transmembrane transport GO:0098660 231 0.022
embryo development ending in birth or egg hatching GO:0009792 34 0.022
Worm
epithelium development GO:0060429 227 0.022
organic acid catabolic process GO:0016054 71 0.022
syncytium formation by plasma membrane fusion GO:0000768 2 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.021
protein oligomerization GO:0051259 173 0.021
single organism carbohydrate metabolic process GO:0044723 193 0.021
negative regulation of cell death GO:0060548 345 0.021
cell development GO:0048468 328 0.021
negative regulation of cellular component organization GO:0051129 235 0.021
positive regulation of cellular component organization GO:0051130 376 0.021
negative regulation of protein metabolic process GO:0051248 391 0.020
purine nucleoside triphosphate catabolic process GO:0009146 392 0.020
protein catabolic process GO:0030163 325 0.020
regulation of cell division GO:0051302 116 0.020
negative regulation of developmental process GO:0051093 247 0.020
hair cycle GO:0042633 28 0.020
cellular ketone metabolic process GO:0042180 80 0.020
regulation of cellular amino acid metabolic process GO:0006521 6 0.019
regulation of neuron apoptotic process GO:0043523 35 0.019
cardiovascular system development GO:0072358 262 0.019
regulation of cell differentiation GO:0045595 393 0.019
signal transduction by phosphorylation GO:0023014 297 0.019
organic hydroxy compound metabolic process GO:1901615 147 0.019
lymphocyte activation GO:0046649 133 0.019
protein tetramerization GO:0051262 47 0.019
organophosphate catabolic process GO:0046434 430 0.019
regulation of cellular ketone metabolic process GO:0010565 50 0.018
cation transport GO:0006812 331 0.018
negative regulation of cellular protein metabolic process GO:0032269 353 0.018
cellular amine metabolic process GO:0044106 41 0.018
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
response to oxygen containing compound GO:1901700 369 0.018
photoreceptor cell differentiation GO:0046530 2 0.018
cellular response to organonitrogen compound GO:0071417 124 0.018
tube development GO:0035295 125 0.018
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.018
positive regulation of mitotic cell cycle GO:0045931 60 0.018
cytoplasmic transport GO:0016482 379 0.018
cellular protein complex assembly GO:0043623 188 0.018
regulation of cell development GO:0060284 161 0.017
positive regulation of protein catabolic process GO:0045732 75 0.017
carboxylic acid catabolic process GO:0046395 71 0.017
biological adhesion GO:0022610 331 0.017
carboxylic acid transport GO:0046942 63 0.017
regulation of cell cycle GO:0051726 393 0.017
chromatin organization GO:0006325 351 0.017
response to organonitrogen compound GO:0010243 156 0.017
atp catabolic process GO:0006200 157 0.016
receptor mediated endocytosis GO:0006898 84 0.016
nitrogen compound transport GO:0071705 191 0.016
cellular response to cytokine stimulus GO:0071345 181 0.016
glycine metabolic process GO:0006544 4 0.016
reproduction GO:0000003 63 0.016
Worm
cell activation GO:0001775 213 0.016
response to organic cyclic compound GO:0014070 204 0.016
purine ribonucleoside metabolic process GO:0046128 437 0.016
neurogenesis GO:0022008 169 0.016
response to mechanical stimulus GO:0009612 51 0.016
pigment metabolic process GO:0042440 16 0.016
vitamin metabolic process GO:0006766 26 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
response to topologically incorrect protein GO:0035966 29 0.015
regulation of cellular response to stress GO:0080135 244 0.015
positive regulation of cell cycle GO:0045787 140 0.015
purine ribonucleoside catabolic process GO:0046130 398 0.015
monocarboxylic acid metabolic process GO:0032787 185 0.015
negative regulation of protein modification process GO:0031400 200 0.015
negative regulation of phosphorylation GO:0042326 174 0.015
glycosyl compound catabolic process GO:1901658 413 0.015
regulation of actin filament based process GO:0032970 141 0.015
regulation of mapk cascade GO:0043408 262 0.015
dephosphorylation GO:0016311 209 0.015
hematopoietic or lymphoid organ development GO:0048534 186 0.014
dicarboxylic acid catabolic process GO:0043649 9 0.014
central nervous system development GO:0007417 123 0.014
single organism cell adhesion GO:0098602 179 0.014
lipid biosynthetic process GO:0008610 177 0.014
cardiac muscle cell contraction GO:0086003 4 0.014
hemopoiesis GO:0030097 180 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
ubiquitin dependent protein catabolic process GO:0006511 206 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
leukocyte mediated cytotoxicity GO:0001909 27 0.014
neurological system process GO:0050877 163 0.014
oocyte development GO:0048599 1 0.014
positive regulation of transport GO:0051050 336 0.014
segmentation GO:0035282 4 0.014
regulation of kinase activity GO:0043549 314 0.014
ribonucleoside triphosphate metabolic process GO:0009199 412 0.014
cell division GO:0051301 168 0.014
regulation of cytokine production GO:0001817 232 0.014
morphogenesis of a branching epithelium GO:0061138 20 0.014
response to molecule of bacterial origin GO:0002237 82 0.014
blastoderm segmentation GO:0007350 2 0.014
nucleoside triphosphate metabolic process GO:0009141 422 0.014
l serine catabolic process GO:0006565 3 0.014
ncrna processing GO:0034470 83 0.013
ion transmembrane transport GO:0034220 338 0.013
cellular protein catabolic process GO:0044257 261 0.013
mitochondrial translation GO:0032543 17 0.013
nucleoside catabolic process GO:0009164 408 0.013
response to hormone GO:0009725 175 0.013
regulation of transferase activity GO:0051338 355 0.013
protein targeting to nucleus GO:0044744 104 0.013
negative regulation of locomotion GO:0040013 118 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.013
response to abiotic stimulus GO:0009628 336 0.013
ribonucleoside monophosphate metabolic process GO:0009161 187 0.013
response to endoplasmic reticulum stress GO:0034976 49 0.013
positive regulation of organelle organization GO:0010638 195 0.013
cell cycle g1 s phase transition GO:0044843 80 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
regulation of interferon gamma production GO:0032649 36 0.013
purine nucleoside triphosphate metabolic process GO:0009144 412 0.013
neural crest cell development GO:0014032 3 0.013
carbohydrate derivative biosynthetic process GO:1901137 207 0.013
basic amino acid transport GO:0015802 3 0.013
regeneration GO:0031099 4 0.012
response to dsrna GO:0043331 25 0.012
response to lipid GO:0033993 206 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
monosaccharide transport GO:0015749 32 0.012
epidermis development GO:0008544 59 0.012
regulation of protein localization GO:0032880 296 0.012
tripartite regional subdivision GO:0007351 2 0.012
cellular response to hormone stimulus GO:0032870 125 0.012
single organism cellular localization GO:1902580 332 0.012
cell adhesion GO:0007155 325 0.012
single organism membrane organization GO:0044802 268 0.012
neuromuscular junction development GO:0007528 3 0.012
lipid localization GO:0010876 106 0.012
anterior posterior axis specification GO:0009948 2 0.012
guanosine containing compound metabolic process GO:1901068 244 0.012
cellular amide metabolic process GO:0043603 69 0.012
nucleotide catabolic process GO:0009166 408 0.012
regulation of cytoskeleton organization GO:0051493 177 0.012
negative regulation of multicellular organismal process GO:0051241 317 0.012
regulation of binding GO:0051098 111 0.012
cytoplasmic translational initiation GO:0002183 6 0.012
regulation of cell cycle process GO:0010564 266 0.012
ribonucleoside triphosphate catabolic process GO:0009203 391 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
regulation of purine nucleotide metabolic process GO:1900542 264 0.011
sulfur compound metabolic process GO:0006790 101 0.011
actin mediated cell contraction GO:0070252 12 0.011
regulation of hormone levels GO:0010817 125 0.011
rna catabolic process GO:0006401 71 0.011
regulation of endopeptidase activity GO:0052548 170 0.011
response to peptide GO:1901652 65 0.011
regulation of cell motility GO:2000145 299 0.011
nucleobase metabolic process GO:0009112 8 0.011
actin filament based movement GO:0030048 17 0.011
mitotic cell cycle GO:0000278 326 0.011
blood vessel morphogenesis GO:0048514 162 0.011
negative regulation of response to external stimulus GO:0032102 83 0.011
positive regulation of apoptotic process GO:0043065 246 0.011
response to sucrose GO:0009744 1 0.011
regulation of intracellular transport GO:0032386 195 0.011
mrna metabolic process GO:0016071 175 0.011
regulation of actin filament length GO:0030832 56 0.011
nerve development GO:0021675 4 0.011
protein acylation GO:0043543 138 0.011
pharynx development GO:0060465 1 0.011
regulation of nucleotide catabolic process GO:0030811 205 0.011
monocarboxylic acid biosynthetic process GO:0072330 67 0.010
leukocyte activation GO:0045321 164 0.010
positive regulation of transferase activity GO:0051347 227 0.010
oocyte differentiation GO:0009994 2 0.010
cell cycle phase transition GO:0044770 173 0.010
secretion GO:0046903 254 0.010
memory GO:0007613 3 0.010
response to insulin GO:0032868 45 0.010
inorganic cation transmembrane transport GO:0098662 194 0.010
regulation of protein kinase activity GO:0045859 289 0.010
canonical wnt signaling pathway involved in negative regulation of apoptotic process GO:0044336 2 0.010
purine nucleoside catabolic process GO:0006152 398 0.010
cellular response to nitrogen compound GO:1901699 144 0.010
cytokine production GO:0001816 247 0.010
tissue morphogenesis GO:0048729 96 0.010
positive regulation of nucleotide catabolic process GO:0030813 185 0.010
metal ion transport GO:0030001 272 0.010
positive regulation of protein polymerization GO:0032273 45 0.010
regulation of response to external stimulus GO:0032101 222 0.010
cap independent translational initiation GO:0002190 4 0.010
regulation of gtpase activity GO:0043087 180 0.010

YARS disease predictions

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 431 0.970
neuropathy DOID:870 52 0.970
neuromuscular disease DOID:440 38 0.395
central nervous system disease DOID:331 186 0.323
neurodegenerative disease DOID:1289 102 0.065
motor neuron disease DOID:231 27 0.049
distal hereditary motor neuropathy DOID:0050582 5 0.049
motor neuritis DOID:683 5 0.049
charcot marie tooth disease type 2 DOID:0050539 15 0.026
charcot marie tooth disease DOID:10595 33 0.026
disease of metabolism DOID:0014667 295 0.018
amino acid metabolic disorder DOID:9252 50 0.018
inherited metabolic disorder DOID:655 242 0.018
cancer DOID:162 167 0.012
disease of cellular proliferation DOID:14566 174 0.012
organ system cancer DOID:0050686 164 0.012
musculoskeletal system disease DOID:17 223 0.011
sensory system disease DOID:0050155 203 0.011
eye and adnexa disease DOID:1492 150 0.011
charcot marie tooth disease intermediate type DOID:0050543 7 0.001