|
|
glucocorticoid catabolic process
|
GO:0006713 |
1 |
1.000
|
Human |
|
|
steroid catabolic process
|
GO:0006706 |
10 |
1.000
|
Human |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
1.000
|
Yeast Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
1.000
|
Yeast Fly |
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
1.000
|
|
|
|
negative regulation of peptidyl serine dephosphorylation
|
GO:1902309 |
1 |
1.000
|
Human |
|
|
glucocorticoid metabolic process
|
GO:0008211 |
10 |
1.000
|
Human |
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
1.000
|
Human |
|
|
negative regulation of exit from mitosis
|
GO:0001100 |
1 |
1.000
|
Yeast |
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
1.000
|
Fly |
|
|
potassium ion transmembrane transport
|
GO:0071805 |
60 |
1.000
|
Human |
|
|
cellular potassium ion transport
|
GO:0071804 |
60 |
1.000
|
Human |
|
|
positive regulation of small gtpase mediated signal transduction
|
GO:0051057 |
12 |
1.000
|
Fly |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
1.000
|
Fly |
|
|
sodium ion transport
|
GO:0006814 |
61 |
1.000
|
Human |
|
|
neuron differentiation
|
GO:0030182 |
138 |
1.000
|
|
|
|
negative regulation of ubiquitin protein ligase activity involved in mitotic cell cycle
|
GO:0051436 |
4 |
1.000
|
Yeast |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
1.000
|
Fly |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
1.000
|
|
|
|
regulation of potassium ion transmembrane transporter activity
|
GO:1901016 |
16 |
1.000
|
Human |
|
|
aggresome assembly
|
GO:0070842 |
4 |
1.000
|
Yeast |
|
|
negative regulation of ubiquitin protein transferase activity
|
GO:0051444 |
8 |
1.000
|
Yeast |
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
1.000
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
1.000
|
Fly |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
1.000
|
Fly |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
1.000
|
Fly |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
1.000
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
1.000
|
Fly |
|
|
membrane repolarization
|
GO:0086009 |
23 |
1.000
|
Human |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
1.000
|
Fly |
|
|
inclusion body assembly
|
GO:0070841 |
17 |
1.000
|
Yeast |
|
|
peptidyl serine dephosphorylation
|
GO:0070262 |
2 |
1.000
|
Human |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
1.000
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
1.000
|
Worm |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
1.000
|
Yeast |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
1.000
|
Worm |
|
|
cellular glucan metabolic process
|
GO:0006073 |
22 |
1.000
|
Yeast |
|
|
female gamete generation
|
GO:0007292 |
2 |
1.000
|
Fly |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
1.000
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
1.000
|
Worm Fly |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
1.000
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
1.000
|
|
|
|
membrane depolarization during action potential
|
GO:0086010 |
10 |
1.000
|
Human |
|
|
lipid metabolic process
|
GO:0006629 |
381 |
1.000
|
Human |
|
|
regulation of membrane repolarization
|
GO:0060306 |
16 |
1.000
|
Human |
|
|
negative regulation of ligase activity
|
GO:0051352 |
8 |
1.000
|
Yeast |
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
1.000
|
Human |
|
|
cell development
|
GO:0048468 |
328 |
1.000
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
1.000
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
1.000
|
Worm Fly |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
1.000
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
1.000
|
Fly |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
1.000
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
1.000
|
|
|
|
protein processing
|
GO:0016485 |
226 |
1.000
|
Human |
|
|
generation of neurons
|
GO:0048699 |
152 |
1.000
|
|
|
|
regulation of potassium ion transmembrane transport
|
GO:1901379 |
20 |
1.000
|
Human |
|
|
cell division
|
GO:0051301 |
168 |
1.000
|
Yeast Worm |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
1.000
|
Human |
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
132 |
0.999
|
Human |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.999
|
Worm Fly |
|
|
glycogen metabolic process
|
GO:0005977 |
22 |
0.999
|
Yeast |
|
|
oocyte development
|
GO:0048599 |
1 |
0.999
|
Fly |
|
|
organelle localization
|
GO:0051640 |
84 |
0.999
|
Worm |
|
|
negative regulation of protein dephosphorylation
|
GO:0035308 |
3 |
0.999
|
Human |
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.999
|
Yeast |
|
|
regulation of sodium ion transmembrane transport
|
GO:1902305 |
23 |
0.999
|
Human |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.999
|
|
|
|
regulation of ion transmembrane transporter activity
|
GO:0032412 |
72 |
0.999
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.999
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.999
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.999
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.999
|
|
|
|
potassium ion transport
|
GO:0006813 |
62 |
0.999
|
Human |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.999
|
|
|
|
regulation of sodium ion transmembrane transporter activity
|
GO:2000649 |
17 |
0.999
|
Human |
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.998
|
Human |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.998
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.998
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
57 |
0.998
|
Human |
|
|
regulation of peptidyl serine dephosphorylation
|
GO:1902308 |
2 |
0.998
|
Human |
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.998
|
Human |
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.998
|
Human |
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.998
|
Human |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.998
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.998
|
Fly |
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
35 |
0.998
|
Human |
|
|
organelle fission
|
GO:0048285 |
149 |
0.998
|
Yeast Worm |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.998
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.997
|
Human Yeast |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.997
|
|
|
|
single fertilization
|
GO:0007338 |
11 |
0.997
|
Worm |
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.997
|
Fly |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.997
|
Yeast Worm Fly |
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.996
|
Worm |
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.996
|
Yeast |
|
|
dna replication initiation
|
GO:0006270 |
6 |
0.996
|
Yeast |
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.996
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.996
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.996
|
|
|
|
glucan metabolic process
|
GO:0044042 |
22 |
0.996
|
Yeast |
|
|
regulation of potassium ion transport
|
GO:0043266 |
24 |
0.996
|
Human |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.994
|
Fly |
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.994
|
Human |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.994
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.994
|
Yeast |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.994
|
Human |
|
|
protein maturation
|
GO:0051604 |
233 |
0.994
|
Human |
|
|
energy reserve metabolic process
|
GO:0006112 |
22 |
0.993
|
Yeast |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.993
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.993
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.993
|
Yeast Worm |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.993
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.993
|
Yeast |
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.993
|
Human |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.993
|
|
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.993
|
Worm |
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.993
|
Yeast |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.992
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.992
|
Human |
|
|
neurological system process
|
GO:0050877 |
163 |
0.992
|
Fly |
|
|
fertilization
|
GO:0009566 |
12 |
0.992
|
Worm |
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.992
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.991
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.991
|
Fly |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.991
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.991
|
|
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.991
|
Human |
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.990
|
Human |
|
|
embryo development
|
GO:0009790 |
123 |
0.990
|
Worm Fly |
|
|
regulation of sodium ion transport
|
GO:0002028 |
24 |
0.990
|
Human |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.990
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.990
|
Yeast Worm |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.990
|
Yeast |
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.989
|
Human |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.989
|
|
|
|
corticosteroid receptor signaling pathway
|
GO:0031958 |
5 |
0.988
|
Human |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.988
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.988
|
|
|
|
cytoplasmic sequestering of protein
|
GO:0051220 |
12 |
0.988
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.988
|
Fly |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.987
|
|
|
|
negative regulation of dephosphorylation
|
GO:0035305 |
63 |
0.987
|
Human |
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.986
|
Human |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.986
|
Human Yeast |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.986
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.984
|
Human |
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.984
|
Worm Fly |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.984
|
Human Yeast |
|
|
nuclear migration
|
GO:0007097 |
1 |
0.984
|
Worm |
|
|
muscle system process
|
GO:0003012 |
81 |
0.983
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.983
|
Yeast |
|
|
action potential
|
GO:0001508 |
34 |
0.983
|
Human |
|
|
aging
|
GO:0007568 |
66 |
0.982
|
Worm |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.982
|
Fly |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.981
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.981
|
|
|
|
keratinization
|
GO:0031424 |
2 |
0.980
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.980
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.980
|
Yeast |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.979
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.978
|
Human Yeast |
|
|
specification of axis polarity
|
GO:0065001 |
1 |
0.977
|
Worm |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.977
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.975
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.974
|
|
|
|
growth
|
GO:0040007 |
202 |
0.974
|
Yeast |
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.973
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.973
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.972
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.971
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.970
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.970
|
Human |
|
|
positive regulation of rac gtpase activity
|
GO:0032855 |
31 |
0.969
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.968
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.967
|
Human |
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.966
|
Yeast |
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.965
|
Human |
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.965
|
Human |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.965
|
|
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.965
|
Yeast |
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.964
|
Human |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.960
|
Human |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.960
|
Fly |
|
|
polysaccharide metabolic process
|
GO:0005976 |
33 |
0.958
|
Yeast |
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.957
|
Worm Fly |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.957
|
|
|
|
establishment of mitotic spindle orientation
|
GO:0000132 |
7 |
0.955
|
Worm |
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.953
|
Human |
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.953
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.950
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.949
|
Human |
|
|
establishment of spindle orientation
|
GO:0051294 |
9 |
0.949
|
Worm |
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.947
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.946
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.944
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.943
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.943
|
|
|
|
developmental maturation
|
GO:0021700 |
28 |
0.939
|
Fly |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.939
|
|
|
|
regulation of transporter activity
|
GO:0032409 |
82 |
0.937
|
Human |
|
|
central nervous system development
|
GO:0007417 |
123 |
0.936
|
Human Zebrafish |
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.934
|
Worm |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.934
|
|
|
|
substantia nigra development
|
GO:0021762 |
45 |
0.932
|
Human |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.929
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.929
|
Yeast Worm Fly |
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.926
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
11 |
0.923
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.922
|
Worm |
|
|
lipid catabolic process
|
GO:0016042 |
84 |
0.922
|
Human |
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.921
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.921
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.921
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.920
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.916
|
Worm Fly |
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.916
|
Human |
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.914
|
Human |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.914
|
Human |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.913
|
Yeast |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.911
|
Yeast Worm |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.906
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.904
|
Human |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.903
|
Human Yeast |
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.901
|
Yeast |
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.893
|
Human |
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.891
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.890
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.889
|
Human Zebrafish |
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.889
|
Yeast |
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.889
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.885
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.884
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.883
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.880
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.880
|
Zebrafish |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.879
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.879
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.871
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.865
|
Yeast |
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.863
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.862
|
Human |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.861
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.860
|
|
|
|
protein folding
|
GO:0006457 |
38 |
0.857
|
Fly |
|
|
exocytosis
|
GO:0006887 |
71 |
0.851
|
|
|
|
exit from mitosis
|
GO:0010458 |
10 |
0.842
|
Yeast |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.840
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.840
|
|
|
|
male gamete generation
|
GO:0048232 |
22 |
0.839
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.837
|
Yeast |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.836
|
Human |
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.834
|
Yeast Worm Fly |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.827
|
|
|
|
regulation of tor signaling
|
GO:0032006 |
30 |
0.826
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.825
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.822
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.817
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.815
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.808
|
Human |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.806
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.804
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
10 |
0.797
|
Worm |
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.794
|
Yeast Fly |
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.790
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.789
|
Yeast |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.789
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.788
|
Human |
|
|
mrna catabolic process
|
GO:0006402 |
56 |
0.785
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
43 |
0.782
|
Yeast |
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.781
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.781
|
Yeast |
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.781
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.765
|
Human |
|
|
regulation of protein dephosphorylation
|
GO:0035304 |
18 |
0.765
|
Human |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.765
|
|
|
|
regulation of axonogenesis
|
GO:0050770 |
16 |
0.759
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.746
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.745
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.744
|
Yeast Worm |
|
|
rna processing
|
GO:0006396 |
255 |
0.744
|
|
|
|
regulation of growth rate
|
GO:0040009 |
1 |
0.741
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.738
|
|
|
|
glucocorticoid receptor signaling pathway
|
GO:0042921 |
5 |
0.727
|
Human |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.720
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.719
|
|
|
|
cellular process involved in reproduction in multicellular organism
|
GO:0022412 |
15 |
0.718
|
Fly |
|
|
positive regulation of ras protein signal transduction
|
GO:0046579 |
12 |
0.716
|
Fly |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.710
|
Mouse |
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.709
|
Yeast |
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.708
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.704
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.703
|
|
|
|
head development
|
GO:0060322 |
108 |
0.702
|
Human Zebrafish |
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.699
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.697
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.694
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.688
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.684
|
Human |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.680
|
Fly |
|
|
reproductive process
|
GO:0022414 |
106 |
0.678
|
Yeast Worm Fly |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.677
|
Yeast |
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.677
|
Human |
|
|
midbrain development
|
GO:0030901 |
45 |
0.659
|
Human |
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.650
|
|
|
|
sexual reproduction
|
GO:0019953 |
37 |
0.650
|
Yeast Worm Fly |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.647
|
Worm |
|
|
protein dna complex assembly
|
GO:0065004 |
64 |
0.639
|
Yeast |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.639
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.636
|
Human |
|
|
cell junction organization
|
GO:0034330 |
79 |
0.631
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.623
|
Yeast |
|
|
cell maturation
|
GO:0048469 |
11 |
0.620
|
Fly |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.609
|
Worm |
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.609
|
Human |
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.601
|
Worm |
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.600
|
|
|
|
establishment of mitotic spindle localization
|
GO:0040001 |
8 |
0.598
|
Worm |
|
|
protein dna complex subunit organization
|
GO:0071824 |
80 |
0.584
|
Yeast |
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.583
|
Worm |
|
|
endocytosis
|
GO:0006897 |
159 |
0.582
|
Worm |
|
|
regulation of exit from mitosis
|
GO:0007096 |
6 |
0.578
|
Yeast |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.576
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.571
|
|
|
|
neural nucleus development
|
GO:0048857 |
47 |
0.571
|
Human |
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.567
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.566
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.565
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.559
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.558
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
45 |
0.554
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.549
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.548
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.542
|
Yeast |
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
18 |
0.536
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.528
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.524
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.522
|
Worm |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.522
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.518
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.511
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.499
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.497
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.496
|
Human |
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.493
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.492
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.489
|
Worm Fly |
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.484
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.467
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.462
|
Human |
|
|
cognition
|
GO:0050890 |
43 |
0.458
|
Fly |
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.458
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.457
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.456
|
Human Yeast |
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.455
|
|
|
|
establishment of spindle localization
|
GO:0051293 |
12 |
0.454
|
Worm |
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.451
|
|
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
81 |
0.448
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.446
|
|
|
|
rna splicing via transesterification reactions
|
GO:0000375 |
90 |
0.439
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.437
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.432
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.422
|
Worm Fly |
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.420
|
Yeast Worm Fly |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.419
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.416
|
Yeast |
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.413
|
|
|
|
mrna splice site selection
|
GO:0006376 |
7 |
0.410
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.406
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.406
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.401
|
Human Yeast |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.391
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.388
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.383
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.380
|
|
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
6 |
0.380
|
|
|
|
spermatogenesis
|
GO:0007283 |
22 |
0.379
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.378
|
Yeast |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.377
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.376
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.372
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.372
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.370
|
|
|
|
multicellular organismal water homeostasis
|
GO:0050891 |
14 |
0.365
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.359
|
|
|
|
negative regulation of microtubule polymerization or depolymerization
|
GO:0031111 |
17 |
0.349
|
|
|
|
cellular protein complex disassembly
|
GO:0043624 |
36 |
0.347
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.346
|
Human |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.341
|
|
|
|
peroxisome organization
|
GO:0007031 |
28 |
0.341
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.333
|
|
|
|
rna catabolic process
|
GO:0006401 |
71 |
0.329
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.326
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.322
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.316
|
Fly |
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.314
|
Fly |
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.311
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.311
|
Human Yeast |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.305
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.302
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.290
|
|
|
|
establishment of skin barrier
|
GO:0061436 |
5 |
0.288
|
|
|
|
regulation of oocyte development
|
GO:0060281 |
1 |
0.288
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.285
|
|
|
|
rap protein signal transduction
|
GO:0032486 |
7 |
0.283
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.279
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.277
|
Yeast |
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.273
|
Yeast |
|
|
keratinocyte proliferation
|
GO:0043616 |
17 |
0.271
|
|
|
|
mitotic spindle checkpoint
|
GO:0071174 |
18 |
0.271
|
Yeast |
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.265
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.265
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.262
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.262
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.254
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.249
|
|
|
|
ribonucleoprotein complex assembly
|
GO:0022618 |
78 |
0.246
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.246
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.245
|
Human |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.244
|
Yeast |
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.243
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
27 |
0.241
|
Yeast |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.239
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.239
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.238
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.238
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.237
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
18 |
0.228
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.226
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.226
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.226
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.223
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.223
|
|
|
|
smoothened signaling pathway
|
GO:0007224 |
14 |
0.218
|
|
|
|
gamete generation
|
GO:0007276 |
25 |
0.217
|
Fly |
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.217
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.211
|
Yeast |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.209
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.209
|
Human |
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.207
|
Yeast |
|
|
establishment of synaptic vesicle localization
|
GO:0097480 |
5 |
0.207
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.206
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.204
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
9 |
0.200
|
Worm |
|
|
nucleus localization
|
GO:0051647 |
1 |
0.200
|
Worm |
|
|
regulation of cell maturation
|
GO:1903429 |
3 |
0.199
|
|
|
|
membrane depolarization
|
GO:0051899 |
26 |
0.196
|
Human |
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.192
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.188
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.185
|
Yeast |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.184
|
|
|
|
cell cycle dna replication
|
GO:0044786 |
11 |
0.184
|
Yeast |
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.182
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.181
|
|
|
|
system process
|
GO:0003008 |
349 |
0.178
|
Fly |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.177
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.176
|
Human |
|
|
mrna processing
|
GO:0006397 |
133 |
0.176
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.175
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.175
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.173
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.169
|
Mouse |
|
|
epithelium development
|
GO:0060429 |
227 |
0.166
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.159
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
22 |
0.159
|
Fly |
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.157
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.157
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.156
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.156
|
|
|
|
regulation of neuronal synaptic plasticity
|
GO:0048168 |
1 |
0.156
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.156
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.153
|
Yeast |
|
|
response to radiation
|
GO:0009314 |
151 |
0.150
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.150
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.150
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.150
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.149
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.148
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.147
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.146
|
|
|
|
mrna splicing via spliceosome
|
GO:0000398 |
89 |
0.145
|
|
|
|
translation
|
GO:0006412 |
132 |
0.144
|
|
|
|
negative regulation of protein depolymerization
|
GO:1901880 |
17 |
0.143
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
38 |
0.141
|
|
|
|
rna splicing
|
GO:0008380 |
131 |
0.141
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.141
|
|
|
|
epithelial cell proliferation involved in lung morphogenesis
|
GO:0060502 |
3 |
0.141
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.141
|
Yeast |
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.139
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.138
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
13 |
0.135
|
Yeast Worm |
|
|
protein depolymerization
|
GO:0051261 |
30 |
0.134
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
68 |
0.133
|
Yeast |
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.132
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.131
|
|
