|
|
chromatin organization
|
GO:0006325 |
351 |
1.000
|
Fly |
|
|
chromatin modification
|
GO:0016568 |
298 |
1.000
|
Fly |
|
|
histone exchange
|
GO:0043486 |
3 |
0.999
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.999
|
|
|
|
atp dependent chromatin remodeling
|
GO:0043044 |
25 |
0.996
|
|
|
|
nucleosome organization
|
GO:0034728 |
66 |
0.991
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.989
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.989
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.989
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
80 |
0.979
|
|
|
|
scf dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031146 |
15 |
0.976
|
|
|
|
chromatin remodeling
|
GO:0006338 |
55 |
0.967
|
Fly |
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.965
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.963
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.961
|
|
|
|
nucleosome positioning
|
GO:0016584 |
3 |
0.942
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.942
|
Mouse |
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.940
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.930
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.908
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.908
|
|
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
0.890
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.888
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.886
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.877
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.876
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.876
|
Fly |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.866
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.861
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.834
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.832
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.828
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.827
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.807
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.804
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.797
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.796
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.768
|
|
|
|
chromatin assembly
|
GO:0031497 |
61 |
0.757
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.745
|
|
|
|
histone monoubiquitination
|
GO:0010390 |
20 |
0.731
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.718
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.714
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.712
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.698
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.689
|
|
|
|
dna geometric change
|
GO:0032392 |
32 |
0.676
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.674
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.662
|
|
|
|
recombinational repair
|
GO:0000725 |
50 |
0.659
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.641
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.619
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.614
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.607
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.602
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.597
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.588
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.582
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.581
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.580
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.579
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.558
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
17 |
0.550
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.546
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.538
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.531
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.527
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.526
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.515
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.510
|
|
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.502
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.502
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.496
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.485
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.483
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.481
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.481
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.480
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.470
|
|
|
|
dna packaging
|
GO:0006323 |
77 |
0.469
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.469
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.468
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.460
|
|
|
|
double strand break repair via homologous recombination
|
GO:0000724 |
50 |
0.450
|
|
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.446
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.445
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.433
|
Fly |
|
|
protein monoubiquitination
|
GO:0006513 |
39 |
0.432
|
|
|
|
small nucleolar ribonucleoprotein complex assembly
|
GO:0000491 |
3 |
0.431
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.431
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.430
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.419
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.397
|
|
|
|
growth
|
GO:0040007 |
202 |
0.394
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.392
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.392
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.388
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.387
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.381
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.369
|
|
|
|
negative regulation of gene expression epigenetic
|
GO:0045814 |
19 |
0.368
|
Fly |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.363
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.358
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.351
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.347
|
|
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.344
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.340
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.334
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.334
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.333
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.328
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.325
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.318
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.317
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.316
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.298
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.288
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.287
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.279
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.277
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.271
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.267
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.265
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.265
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.259
|
|
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.257
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.255
|
|
|
|
regulation of ligase activity
|
GO:0051340 |
29 |
0.250
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.246
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.245
|
Fly |
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.241
|
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
18 |
0.240
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.233
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.230
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.229
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.228
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.228
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.224
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.222
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.220
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.219
|
|
|
|
cellular response to light stimulus
|
GO:0071482 |
34 |
0.219
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.215
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.213
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.210
|
|
|
|
hormone secretion
|
GO:0046879 |
65 |
0.209
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.207
|
|
|
|
regulation of growth rate
|
GO:0040009 |
1 |
0.205
|
|
|
|
ectodermal placode formation
|
GO:0060788 |
1 |
0.204
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.203
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.201
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.200
|
Fly |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.200
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.199
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.198
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
32 |
0.197
|
|
|
|
regulation of dna dependent dna replication
|
GO:0090329 |
19 |
0.195
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.195
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.194
|
Fly |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.185
|
|
|
|
rostrocaudal neural tube patterning
|
GO:0021903 |
1 |
0.183
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.183
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.183
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.182
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.181
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.179
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.179
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.178
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.177
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.177
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.176
|
|
|
|
telomere maintenance
|
GO:0000723 |
32 |
0.176
|
|
|
|
signal release
|
GO:0023061 |
70 |
0.174
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.171
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.170
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.169
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.168
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.167
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.165
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
16 |
0.165
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.164
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.164
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.163
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.160
|
|
|
|
system process
|
GO:0003008 |
349 |
0.159
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.154
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.154
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.152
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.151
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.151
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.147
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.146
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.146
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.145
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.144
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.143
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.143
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.143
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.142
|
|
|
|
hormone transport
|
GO:0009914 |
68 |
0.141
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.141
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.141
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.139
|
Fly |
|
|
histone h2a ubiquitination
|
GO:0033522 |
17 |
0.137
|
|
|
|
viral gene expression
|
GO:0019080 |
35 |
0.136
|
|
|
|
heart growth
|
GO:0060419 |
6 |
0.136
|
|
|
|
histone h2a acetylation
|
GO:0043968 |
12 |
0.135
|
|
|
|
melanocyte differentiation
|
GO:0030318 |
2 |
0.134
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.134
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.134
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.133
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.132
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.131
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
35 |
0.131
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.130
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.130
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.128
|
|
|
|
telomere organization
|
GO:0032200 |
33 |
0.128
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.126
|
|
|
|
aging
|
GO:0007568 |
66 |
0.125
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.125
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.124
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.123
|
Fly |
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.121
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.120
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.118
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.117
|
Zebrafish |
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.117
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.115
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.113
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.113
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.113
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.113
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.112
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.110
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.110
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.110
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.110
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.109
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.106
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.106
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
43 |
0.106
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.105
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.104
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.104
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.104
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.104
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.103
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.103
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.103
|
|
|
|
dna duplex unwinding
|
GO:0032508 |
30 |
0.102
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.102
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.101
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.101
|
|
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.100
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.099
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.099
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.099
|
|
|
|
ectodermal placode development
|
GO:0071696 |
1 |
0.098
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.098
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.098
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.097
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.097
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.095
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.095
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.093
|
|
|
|
telomere maintenance via recombination
|
GO:0000722 |
4 |
0.093
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.092
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.092
|
|
|
|
embryonic digestive tract morphogenesis
|
GO:0048557 |
2 |
0.091
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.091
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.090
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.089
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.088
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.088
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.087
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.086
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.086
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.086
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.086
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.085
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.085
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.083
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.083
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.082
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.082
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.082
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.081
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.081
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.081
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.080
|
|
|
|
tongue development
|
GO:0043586 |
1 |
0.080
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
15 |
0.079
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.079
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.079
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.079
|
|
|
|
positive regulation of translation
|
GO:0045727 |
35 |
0.079
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.078
|
|
|
|
histone deacetylation
|
GO:0016575 |
32 |
0.078
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.078
|
|
|
|
positive regulation of epithelial to mesenchymal transition
|
GO:0010718 |
22 |
0.078
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.077
|
|
|
|
histone h2a monoubiquitination
|
GO:0035518 |
11 |
0.077
|
|
|
|
specification of symmetry
|
GO:0009799 |
16 |
0.077
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.077
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.076
|
Human |
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.076
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.075
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.075
|
|
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.075
|
|
|
|
embryonic camera type eye morphogenesis
|
GO:0048596 |
2 |
0.075
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.075
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.075
|
|
|
|
gene silencing by mirna
|
GO:0035195 |
23 |
0.075
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.074
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.074
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.074
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.074
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.074
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.073
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.073
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.073
|
|
|
|
uv damage excision repair
|
GO:0070914 |
7 |
0.073
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.072
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.072
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.071
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.071
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.071
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.071
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.070
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.070
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.070
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.069
|
|
|
|
modulation by host of viral transcription
|
GO:0043921 |
20 |
0.069
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.069
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.068
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.068
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.068
|
|
|
|
mitotic recombination
|
GO:0006312 |
8 |
0.067
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.067
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.067
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.066
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.066
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.066
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.066
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.066
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.065
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.065
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.065
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.065
|
|
|
|
regulation of histone acetylation
|
GO:0035065 |
19 |
0.065
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.065
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.064
|
|
|
|
heart valve formation
|
GO:0003188 |
2 |
0.064
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.063
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.063
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.063
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
38 |
0.063
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.063
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.063
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.063
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.063
|
|
|
|
hair cycle
|
GO:0042633 |
28 |
0.062
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.062
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.062
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.062
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
9 |
0.061
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
19 |
0.061
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.061
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.060
|
Fly |
|
|
viral transcription
|
GO:0019083 |
35 |
0.060
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.060
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.060
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.060
|
|
|
|
insulin secretion
|
GO:0030073 |
39 |
0.059
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.059
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.059
|
|
|
|
response to fungus
|
GO:0009620 |
4 |
0.058
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.058
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.058
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.058
|
|
|
|
spindle assembly
|
GO:0051225 |
29 |
0.058
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.057
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.057
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.057
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.057
|
|
|
|
cell proliferation involved in heart valve development
|
GO:2000793 |
1 |
0.057
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
9 |
0.056
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.056
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.056
|
Zebrafish |
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.056
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
45 |
0.056
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.056
|
|
|
|
blastocyst formation
|
GO:0001825 |
3 |
0.056
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
43 |
0.056
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.056
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.056
|
|
|
|
multi organism metabolic process
|
GO:0044033 |
41 |
0.056
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.055
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.055
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.055
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.054
|
|
|
|
regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033143 |
32 |
0.054
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.054
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.054
|
Fly |
|
|
cell division
|
GO:0051301 |
168 |
0.054
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.053
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.053
|
|
|
|
organ growth
|
GO:0035265 |
12 |
0.053
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.053
|
|
|
|
negative regulation of neural precursor cell proliferation
|
GO:2000178 |
1 |
0.053
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.053
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.052
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.052
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.052
|
|
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.052
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.052
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.051
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.051
|
|
|
|
brain morphogenesis
|
GO:0048854 |
1 |
0.051
|
|
|
|
regulation of dna templated transcription elongation
|
GO:0032784 |
23 |
0.051
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.050
|
|
|
|
phototransduction
|
GO:0007602 |
3 |
0.050
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.050
|
Fly |
|
|
reproductive system development
|
GO:0061458 |
56 |
0.050
|
Human |
|
|
positive regulation of rho protein signal transduction
|
GO:0035025 |
4 |
0.049
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.049
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.049
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.049
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.049
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.048
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.048
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.048
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.048
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.048
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.047
|
Fly |
|
|
nuclear import
|
GO:0051170 |
106 |
0.047
|
|
|
|
negative regulation of axonogenesis
|
GO:0050771 |
4 |
0.047
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.047
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.047
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.046
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.046
|
|
|
|
positive regulation of lipase activity
|
GO:0060193 |
28 |
0.046
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.046
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.046
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.045
|
|
|
|
modulation by host of symbiont transcription
|
GO:0052472 |
20 |
0.045
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.045
|
|
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.045
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.045
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.045
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.045
|
|
|
|
modification by host of symbiont morphology or physiology
|
GO:0051851 |
26 |
0.044
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
23 |
0.044
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.044
|
|
|
|
transcription elongation from rna polymerase ii promoter
|
GO:0006368 |
18 |
0.044
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.044
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.044
|
|
|
|
limb development
|
GO:0060173 |
23 |
0.044
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.043
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.043
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.043
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.043
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.043
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.043
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.043
|
|
|
|
lateral mesoderm development
|
GO:0048368 |
1 |
0.042
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.042
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.042
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.042
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.042
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.042
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.042
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.042
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.041
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.041
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.041
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.041
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.041
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.040
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.040
|
|
|
|
axonemal dynein complex assembly
|
GO:0070286 |
11 |
0.040
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
0.040
|
|
|
|
regulation of camp biosynthetic process
|
GO:0030817 |
45 |
0.040
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.040
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.039
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.039
|
|
|
|
regulation of organ growth
|
GO:0046620 |
7 |
0.039
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.039
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.039
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.039
|
|
|
|
adenylate cyclase activating g protein coupled receptor signaling pathway
|
GO:0007189 |
18 |
0.039
|
|