Homo sapiens

0 known processes

ZNF253

zinc finger protein 253

(Aliases: BMZF1,FLJ90391,ZNF411,BMZF-1)

ZNF253 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of interleukin 1 mediated signaling pathway GO:2000659 3 1.000
negative regulation of interleukin 1 mediated signaling pathway GO:2000660 2 0.998
negative regulation of jun kinase activity GO:0043508 4 0.991
negative regulation of cytokine mediated signaling pathway GO:0001960 22 0.986
regulation of osteoclast differentiation GO:0045670 18 0.973
negative regulation of tumor necrosis factor mediated signaling pathway GO:0010804 7 0.967
interleukin 1 mediated signaling pathway GO:0070498 12 0.958
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.949
osteoclast differentiation GO:0030316 21 0.943
negative regulation of myeloid cell differentiation GO:0045638 42 0.934
cellular response to interleukin 1 GO:0071347 35 0.931
negative regulation of myeloid leukocyte differentiation GO:0002762 16 0.863
negative regulation of jnk cascade GO:0046329 16 0.859
stress activated protein kinase signaling cascade GO:0031098 94 0.849
regulation of jun kinase activity GO:0043506 27 0.840
negative regulation of map kinase activity GO:0043407 27 0.822
response to interleukin 1 GO:0070555 47 0.815
regulation of jnk cascade GO:0046328 73 0.815
regulation of map kinase activity GO:0043405 108 0.811
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.810
appendage morphogenesis GO:0035107 16 0.807
regulation of cytokine mediated signaling pathway GO:0001959 41 0.795
negative regulation of leukocyte differentiation GO:1902106 24 0.776
regulation of transcription regulatory region dna binding GO:2000677 15 0.771
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.769
negative regulation of stress activated mapk cascade GO:0032873 19 0.741
midbrain development GO:0030901 45 0.739
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.737
myeloid cell differentiation GO:0030099 117 0.736
regulation of leukocyte differentiation GO:1902105 61 0.723
jnk cascade GO:0007254 80 0.722
regulation of tumor necrosis factor mediated signaling pathway GO:0010803 12 0.722
response to cytokine GO:0034097 232 0.717
negative regulation of binding GO:0051100 57 0.716
negative regulation of response to cytokine stimulus GO:0060761 25 0.711
regulation of stress activated mapk cascade GO:0032872 84 0.703
cytokine mediated signaling pathway GO:0019221 109 0.686
regulation of protein serine threonine kinase activity GO:0071900 179 0.685
regulation of kinase activity GO:0043549 314 0.676
response to tumor necrosis factor GO:0034612 76 0.659
substantia nigra development GO:0021762 45 0.658
regulation of mapk cascade GO:0043408 262 0.650
regulation of myeloid leukocyte differentiation GO:0002761 39 0.644
regulation of binding GO:0051098 111 0.642
negative regulation of protein metabolic process GO:0051248 391 0.621
cellular response to cytokine stimulus GO:0071345 181 0.619
i kappab kinase nf kappab signaling GO:0007249 166 0.612
negative regulation of protein phosphorylation GO:0001933 140 0.598
regulation of myeloid cell differentiation GO:0045637 81 0.596
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.595
negative regulation of immune system process GO:0002683 136 0.565
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.535
cellular response to tumor necrosis factor GO:0071356 63 0.535
negative regulation of multicellular organismal process GO:0051241 317 0.535
immune system development GO:0002520 195 0.529
mapk cascade GO:0000165 288 0.523
regulation of protein kinase activity GO:0045859 289 0.510
negative regulation of cellular protein metabolic process GO:0032269 353 0.490
neural nucleus development GO:0048857 47 0.476
signal transduction by phosphorylation GO:0023014 297 0.467
regulation of cell differentiation GO:0045595 393 0.455
limb morphogenesis GO:0035108 16 0.447
appendage development GO:0048736 23 0.436
hemopoiesis GO:0030097 180 0.424
negative regulation of stress activated protein kinase signaling cascade GO:0070303 19 0.405
regulation of cellular response to stress GO:0080135 244 0.405
hematopoietic or lymphoid organ development GO:0048534 186 0.404
stress activated mapk cascade GO:0051403 93 0.404
negative regulation of developmental process GO:0051093 247 0.396
negative regulation of osteoclast differentiation GO:0045671 8 0.383
negative regulation of cell differentiation GO:0045596 171 0.379
regulation of transferase activity GO:0051338 355 0.374
negative regulation of transferase activity GO:0051348 124 0.347
negative regulation of transcription regulatory region dna binding GO:2000678 6 0.345
myeloid leukocyte differentiation GO:0002573 60 0.342
regulation of dna binding GO:0051101 37 0.339
limb development GO:0060173 23 0.336
negative regulation of phosphate metabolic process GO:0045936 267 0.336
negative regulation of dna binding GO:0043392 18 0.309
leukocyte differentiation GO:0002521 98 0.308
negative regulation of phosphorus metabolic process GO:0010563 267 0.288
negative regulation of intracellular signal transduction GO:1902532 183 0.279
negative regulation of protein modification process GO:0031400 200 0.233
nervous system development GO:0007399 293 0.228
negative regulation of mapk cascade GO:0043409 56 0.191
negative regulation of phosphorylation GO:0042326 174 0.188
regulation of response to cytokine stimulus GO:0060759 46 0.185
negative regulation of kinase activity GO:0033673 106 0.178
negative regulation of catalytic activity GO:0043086 335 0.176
brain development GO:0007420 97 0.165
head development GO:0060322 108 0.151
tumor necrosis factor mediated signaling pathway GO:0033209 27 0.149
negative regulation of protein kinase activity GO:0006469 98 0.140
central nervous system development GO:0007417 123 0.137
positive regulation of transcription during mitosis GO:0045897 2 0.133
positive regulation of transcription from rna polymerase ii promoter during mitosis GO:0046022 1 0.089
regulation of transcription from rna polymerase ii promoter mitotic GO:0046021 1 0.065
regulation of transcription during mitosis GO:0045896 2 0.045
post embryonic development GO:0009791 2 0.042
female gamete generation GO:0007292 2 0.037
amine metabolic process GO:0009308 44 0.037
cellular amino acid metabolic process GO:0006520 116 0.036
multicellular organismal aging GO:0010259 3 0.033
regulation of cellular amine metabolic process GO:0033238 11 0.032
posttranscriptional regulation of gene expression GO:0010608 213 0.032
positive regulation of cellular amine metabolic process GO:0033240 7 0.031
regulation of cellular amino acid metabolic process GO:0006521 6 0.031
cellular amine metabolic process GO:0044106 41 0.029
positive regulation of phosphorylation GO:0042327 394 0.029
cellular ketone metabolic process GO:0042180 80 0.029
determination of adult lifespan GO:0008340 2 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
translation GO:0006412 132 0.025
regulation of cellular ketone metabolic process GO:0010565 50 0.024
segmentation GO:0035282 4 0.024
intracellular protein transport GO:0006886 270 0.024
single organism cellular localization GO:1902580 332 0.023
organophosphate catabolic process GO:0046434 430 0.023
ribonucleotide catabolic process GO:0009261 405 0.023
purine containing compound catabolic process GO:0072523 411 0.021
cell morphogenesis GO:0000902 296 0.021
locomotory behavior GO:0007626 1 0.020
purine nucleoside triphosphate metabolic process GO:0009144 412 0.020
cytoplasmic transport GO:0016482 379 0.020
oogenesis GO:0048477 2 0.020
ribonucleoside triphosphate metabolic process GO:0009199 412 0.020
nucleoside phosphate catabolic process GO:1901292 412 0.019
positive regulation of apoptotic process GO:0043065 246 0.019
purine ribonucleoside catabolic process GO:0046130 398 0.019
purine nucleotide catabolic process GO:0006195 405 0.018
negative regulation of cell death GO:0060548 345 0.018
nucleotide catabolic process GO:0009166 408 0.018
ribonucleoside catabolic process GO:0042454 406 0.018
mitotic cell cycle GO:0000278 326 0.018
nucleoside triphosphate metabolic process GO:0009141 422 0.018
purine ribonucleoside metabolic process GO:0046128 437 0.018
ribonucleoside triphosphate catabolic process GO:0009203 391 0.018
glycosyl compound catabolic process GO:1901658 413 0.017
negative regulation of programmed cell death GO:0043069 321 0.017
purine nucleoside catabolic process GO:0006152 398 0.017
protein catabolic process GO:0030163 325 0.017
response to oxygen containing compound GO:1901700 369 0.017
regulation of anatomical structure morphogenesis GO:0022603 286 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.016
purine nucleoside triphosphate catabolic process GO:0009146 392 0.016
anterior posterior axis specification GO:0009948 2 0.016
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.015
positive regulation of transport GO:0051050 336 0.015
positive regulation of cell proliferation GO:0008284 301 0.015
establishment of protein localization to organelle GO:0072594 172 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.015
positive regulation of programmed cell death GO:0043068 249 0.015
neuromuscular junction development GO:0007528 3 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
regulation of protein localization GO:0032880 296 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
purine ribonucleotide catabolic process GO:0009154 404 0.015
positive regulation of catabolic process GO:0009896 310 0.015
nucleoside triphosphate catabolic process GO:0009143 394 0.015
blastoderm segmentation GO:0007350 2 0.015
memory GO:0007613 3 0.015
rna processing GO:0006396 255 0.014
positive regulation of cellular component organization GO:0051130 376 0.014
cellular component morphogenesis GO:0032989 314 0.014
ribonucleoside monophosphate metabolic process GO:0009161 187 0.014
regulation of intracellular transport GO:0032386 195 0.014
maintenance of location GO:0051235 112 0.014
regulation of translation GO:0006417 89 0.014
biological adhesion GO:0022610 331 0.014
negative regulation of apoptotic process GO:0043066 316 0.014
protein localization to organelle GO:0033365 280 0.014
innate immune response GO:0045087 178 0.014
regulation of cellular component biogenesis GO:0044087 281 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.013
positive regulation of cell death GO:0010942 263 0.013
nucleoside monophosphate metabolic process GO:0009123 191 0.013
chemical homeostasis GO:0048878 306 0.013
regulation of cytoplasmic transport GO:1903649 149 0.013
carbohydrate derivative biosynthetic process GO:1901137 207 0.013
peripheral nervous system development GO:0007422 2 0.013
immune response GO:0006955 307 0.013
regulation of proteolysis GO:0030162 293 0.013
positive regulation of cellular component movement GO:0051272 181 0.013
spermatid differentiation GO:0048515 4 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
regulation of cell cycle process GO:0010564 266 0.013
positive regulation of protein phosphorylation GO:0001934 313 0.013
rna splicing GO:0008380 131 0.013
regulation of nucleotide metabolic process GO:0006140 269 0.013
cellular macromolecular complex assembly GO:0034622 324 0.013
negative regulation of transport GO:0051051 176 0.012
rna interference GO:0016246 4 0.012
cell growth GO:0016049 160 0.012
regulation of cytokine production GO:0001817 232 0.012
spermatid development GO:0007286 4 0.012
cellular lipid metabolic process GO:0044255 303 0.012
positive regulation of hydrolase activity GO:0051345 331 0.012
positive regulation of cell motility GO:2000147 177 0.012
nucleoside catabolic process GO:0009164 408 0.012
positive regulation of binding GO:0051099 45 0.012
cellular response to endogenous stimulus GO:0071495 336 0.012
protein ubiquitination GO:0016567 314 0.012
protein targeting GO:0006605 187 0.012
regulation of establishment of protein localization GO:0070201 242 0.012
positive regulation of transferase activity GO:0051347 227 0.012
single organism nuclear import GO:1902593 104 0.012
negative regulation of cell proliferation GO:0008285 228 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
response to abiotic stimulus GO:0009628 336 0.012
cytokine production GO:0001816 247 0.012
positive regulation of cellular component biogenesis GO:0044089 158 0.012
organonitrogen compound biosynthetic process GO:1901566 200 0.012
rhythmic behavior GO:0007622 2 0.012
regulation of cell cycle GO:0051726 393 0.012
dephosphorylation GO:0016311 209 0.012
system process GO:0003008 349 0.012
protein modification by small protein conjugation GO:0032446 342 0.012
purine nucleoside monophosphate metabolic process GO:0009126 186 0.012
nucleoside monophosphate catabolic process GO:0009125 159 0.011
response to fungus GO:0009620 4 0.011
oocyte development GO:0048599 1 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.011
hindbrain development GO:0030902 3 0.011
mitotic cell cycle process GO:1903047 286 0.011
regulation of mitotic cell cycle GO:0007346 189 0.011
nuclear transport GO:0051169 179 0.011
regulation of protein catabolic process GO:0042176 155 0.011
defense response GO:0006952 315 0.011
response to growth factor GO:0070848 205 0.011
negative regulation of hydrolase activity GO:0051346 182 0.011
positive regulation of cell differentiation GO:0045597 211 0.011
compound eye development GO:0048749 1 0.011
chromatin organization GO:0006325 351 0.011
cell cycle phase transition GO:0044770 173 0.011
nitrogen compound transport GO:0071705 191 0.011
positive regulation of synaptic transmission GO:0050806 4 0.011
regulation of secretion by cell GO:1903530 177 0.011
cell projection organization GO:0030030 252 0.011
rna splicing via transesterification reactions GO:0000375 90 0.011
positive regulation of cellular catabolic process GO:0031331 284 0.011
regeneration GO:0031099 4 0.011
transmembrane transport GO:0055085 399 0.011
apoptotic signaling pathway GO:0097190 268 0.011
meiosis i GO:0007127 4 0.011
cellular macromolecule catabolic process GO:0044265 380 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
sex determination GO:0007530 3 0.011
mrna metabolic process GO:0016071 175 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
protein localization to nucleus GO:0034504 136 0.011
positive regulation of cytokine production GO:0001819 167 0.011
regulation of feeding behavior GO:0060259 3 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.010
glycoprotein metabolic process GO:0009100 110 0.010
reactive oxygen species metabolic process GO:0072593 75 0.010
regulation of protein transport GO:0051223 213 0.010
regulation of multi organism process GO:0043900 157 0.010
regulation of cell motility GO:2000145 299 0.010
nerve development GO:0021675 4 0.010
growth GO:0040007 202 0.010
regulation of secretion GO:0051046 194 0.010
atp metabolic process GO:0046034 176 0.010
regulation of neural precursor cell proliferation GO:2000177 4 0.010
mitotic cell cycle phase transition GO:0044772 162 0.010
regulation of purine nucleotide metabolic process GO:1900542 264 0.010
protein maturation GO:0051604 233 0.010
response to external biotic stimulus GO:0043207 261 0.010
negative regulation of translation GO:0017148 37 0.010
negative regulation of cellular component organization GO:0051129 235 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.010
chromatin modification GO:0016568 298 0.010
histone modification GO:0016570 251 0.010
somitogenesis GO:0001756 2 0.010
positive regulation of cell migration GO:0030335 172 0.010
secretion by cell GO:0032940 226 0.010
positive regulation of protein kinase activity GO:0045860 190 0.010
cellular response to oxygen containing compound GO:1901701 276 0.010
sensory perception of pain GO:0019233 4 0.010
lipid metabolic process GO:0006629 381 0.010

ZNF253 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.037
inherited metabolic disorder DOID:655 242 0.022
cancer DOID:162 167 0.021
disease of cellular proliferation DOID:14566 174 0.021
sensory system disease DOID:0050155 203 0.019
nervous system disease DOID:863 431 0.019
immune system disease DOID:2914 155 0.016
eye and adnexa disease DOID:1492 150 0.015
eye disease DOID:5614 149 0.015
organ system cancer DOID:0050686 164 0.015
central nervous system disease DOID:331 186 0.013
musculoskeletal system disease DOID:17 223 0.011
retinal disease DOID:5679 118 0.011