|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.952
|
Human |
|
|
neural tube formation
|
GO:0001841 |
3 |
0.886
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.878
|
Human |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.808
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.640
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.614
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.531
|
Human |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.444
|
Human |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.419
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.414
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.347
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.334
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.332
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.330
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.323
|
Human |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.316
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.300
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.280
|
Human |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.249
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.241
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.220
|
|
|
|
protein k63 linked ubiquitination
|
GO:0070534 |
31 |
0.215
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.214
|
Human |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.210
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.209
|
Human |
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.206
|
Human |
|
|
dna repair
|
GO:0006281 |
198 |
0.194
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.193
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.193
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.185
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.182
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.182
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.174
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.174
|
Human |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.170
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.170
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.164
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.157
|
Human |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.150
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.149
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.149
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.143
|
|
|
|
histone h2a ubiquitination
|
GO:0033522 |
17 |
0.142
|
|
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.140
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.140
|
Human |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.138
|
Human |
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.138
|
|
|
|
activation of jnkk activity
|
GO:0007256 |
1 |
0.134
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.128
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.126
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.125
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.121
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.121
|
Human |
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.121
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.118
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.117
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.117
|
|
|
|
tube closure
|
GO:0060606 |
3 |
0.117
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.115
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.113
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.113
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.109
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.104
|
Human |
|
|
hindbrain development
|
GO:0030902 |
3 |
0.103
|
|
|
|
regulation of glutamine family amino acid metabolic process
|
GO:0000820 |
2 |
0.100
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.098
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.096
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.096
|
|
|
|
negative regulation of protein ubiquitination
|
GO:0031397 |
35 |
0.095
|
Human |
|
|
defense response
|
GO:0006952 |
315 |
0.093
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.093
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.093
|
Human |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.091
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.090
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.088
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.086
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.083
|
Human |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.083
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.082
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.082
|
Human |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.081
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.081
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.081
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.081
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.081
|
|
|
|
protein complex disassembly
|
GO:0043241 |
52 |
0.079
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.078
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.078
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.077
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.076
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.076
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.076
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.076
|
|
|
|
protein autoubiquitination
|
GO:0051865 |
37 |
0.076
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.074
|
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
1 |
0.073
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.070
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.070
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.070
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.069
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.068
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.066
|
|
|
|
regulation of synaptic vesicle exocytosis
|
GO:2000300 |
2 |
0.066
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.066
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.066
|
Human |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.065
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.065
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.065
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.064
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.064
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.062
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.061
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.061
|
|
|
|
negative regulation of protein polyubiquitination
|
GO:1902915 |
4 |
0.060
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.060
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.059
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.058
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.058
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.057
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.057
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.057
|
|
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
27 |
0.056
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.056
|
Human |
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.056
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.056
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.056
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.055
|
Human |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.055
|
Human |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.055
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.054
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.054
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.053
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.052
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.052
|
|
|
|
glutamate metabolic process
|
GO:0006536 |
10 |
0.051
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.051
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.050
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.050
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.050
|
Human |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.049
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.049
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.049
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.048
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.048
|
Human |
|
|
embryo development
|
GO:0009790 |
123 |
0.048
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.047
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.047
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.047
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.046
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.046
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.045
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.045
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.045
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.045
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.045
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.044
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.043
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.043
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.043
|
|
|
|
microtubule anchoring
|
GO:0034453 |
24 |
0.042
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.042
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.042
|
Human |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.042
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.042
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.042
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.041
|
|
|
|
regulation of odontogenesis
|
GO:0042481 |
4 |
0.041
|
|
|
|
canonical wnt signaling pathway involved in negative regulation of apoptotic process
|
GO:0044336 |
2 |
0.041
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.041
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.040
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.040
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.040
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.039
|
Human |
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.039
|
Human |
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.038
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.038
|
|
|
|
negative regulation of response to dna damage stimulus
|
GO:2001021 |
33 |
0.037
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.037
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.037
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.037
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.036
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.036
|
Human |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.036
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.036
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.036
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.036
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.035
|
Human |
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.035
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.035
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.035
|
Human |
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.035
|
|
|
|
protein k63 linked deubiquitination
|
GO:0070536 |
21 |
0.034
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.034
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.034
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.033
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.033
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.033
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
24 |
0.033
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.033
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.033
|
|
|
|
endosome transport via multivesicular body sorting pathway
|
GO:0032509 |
3 |
0.033
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.032
|
Human |
|
|
negative regulation of protein modification by small protein conjugation or removal
|
GO:1903321 |
41 |
0.032
|
Human |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.032
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.032
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.032
|
|
|
|
negative regulation of striated muscle contraction
|
GO:0045988 |
2 |
0.032
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
19 |
0.032
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.032
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.032
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.032
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.032
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.032
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.032
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.031
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.030
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.030
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.030
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.030
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.030
|
Human |
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.030
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.030
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.030
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.030
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.029
|
Human |
|
|
nuclear migration
|
GO:0007097 |
1 |
0.029
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.029
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.029
|
|
|
|
negative regulation of chromatin modification
|
GO:1903309 |
21 |
0.029
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
38 |
0.029
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.029
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.029
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.029
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.029
|
Human |
|
|
regulation of dendrite morphogenesis
|
GO:0048814 |
11 |
0.028
|
|
|
|
dna packaging
|
GO:0006323 |
77 |
0.028
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.028
|
|
|
|
lysosomal transport
|
GO:0007041 |
33 |
0.028
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.028
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.028
|
Human |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.028
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.028
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.028
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.028
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.028
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.028
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.027
|
Human |
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.027
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.027
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.027
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.027
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.027
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.026
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.026
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.026
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.026
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.026
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.026
|
|
|
|
regulation of protein polyubiquitination
|
GO:1902914 |
8 |
0.026
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.026
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.025
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.025
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.025
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.025
|
Human |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.025
|
|
|
|
male meiosis
|
GO:0007140 |
1 |
0.025
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.025
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.025
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.025
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.025
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.025
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.025
|
|
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.025
|
|
|
|
protein localization to adherens junction
|
GO:0071896 |
2 |
0.025
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.024
|
|
|
|
protein k48 linked deubiquitination
|
GO:0071108 |
19 |
0.024
|
Human |
|
|
endocytosis
|
GO:0006897 |
159 |
0.024
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.024
|
|
|
|
protein depolymerization
|
GO:0051261 |
30 |
0.024
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
37 |
0.024
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.024
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.024
|
Human |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.024
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.024
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.024
|
|
|
|
regulation of defense response to virus
|
GO:0050688 |
33 |
0.024
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.024
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.024
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.024
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.023
|
|
|
|
cellular response to misfolded protein
|
GO:0071218 |
2 |
0.023
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.023
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.023
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.023
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.023
|
|
|
|
negative regulation of protein k63 linked ubiquitination
|
GO:1900045 |
4 |
0.023
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.023
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.023
|
|
|
|
forebrain generation of neurons
|
GO:0021872 |
3 |
0.023
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.023
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.023
|
Human |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.022
|
|
|
|
rna transport
|
GO:0050658 |
39 |
0.022
|
|
|
|
organic acid biosynthetic process
|
GO:0016053 |
97 |
0.022
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.022
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.022
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.022
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.022
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.022
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.022
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.022
|
|
|
|
positive regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031666 |
4 |
0.022
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.022
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.021
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.021
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.021
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.021
|
|
|
|
tachykinin receptor signaling pathway
|
GO:0007217 |
3 |
0.021
|
|
|
|
synaptic vesicle exocytosis
|
GO:0016079 |
3 |
0.021
|
|
|
|
regulation of endosome size
|
GO:0051036 |
3 |
0.021
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.021
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.021
|
|
|
|
mrna transport
|
GO:0051028 |
30 |
0.021
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.021
|
|
|
|
prostate gland development
|
GO:0030850 |
3 |
0.021
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.021
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.021
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.021
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.021
|
Human |
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.021
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.020
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.020
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.020
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.020
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.020
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.020
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.020
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.020
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.020
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.020
|
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.020
|
|
|
|
negative regulation of protein complex disassembly
|
GO:0043242 |
20 |
0.020
|
|
|
|
sensory perception of sweet taste
|
GO:0050916 |
2 |
0.020
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.020
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.020
|
Human |
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.020
|
|
|
|
intracellular estrogen receptor signaling pathway
|
GO:0030520 |
23 |
0.020
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.020
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.020
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.020
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.019
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.019
|
Human |
|
|
epithelial tube formation
|
GO:0072175 |
5 |
0.019
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.019
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.019
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.019
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.019
|
|
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.019
|
|
|
|
regulation of double strand break repair
|
GO:2000779 |
22 |
0.019
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.019
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.018
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.018
|
|
|
|
nucleic acid transport
|
GO:0050657 |
39 |
0.018
|
|
|
|
regulation of hemoglobin biosynthetic process
|
GO:0046984 |
1 |
0.018
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.018
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.018
|
Human |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.018
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.018
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.018
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.018
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
46 |
0.018
|
|
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.018
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.018
|
|
|
|
negative regulation of protein depolymerization
|
GO:1901880 |
17 |
0.018
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.018
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.018
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.018
|
|
|
|
muscle cell cellular homeostasis
|
GO:0046716 |
3 |
0.017
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.017
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.017
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.017
|
|
|
|
rna localization
|
GO:0006403 |
41 |
0.017
|
|
|
|
negative regulation of microtubule polymerization or depolymerization
|
GO:0031111 |
17 |
0.017
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.017
|
|
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.017
|
|
|
|
protein localization to lysosome
|
GO:0061462 |
11 |
0.017
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.017
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.017
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.017
|
Human |
|
|
golgi vesicle transport
|
GO:0048193 |
80 |
0.017
|
|
|
|
positive regulation of t cell cytokine production
|
GO:0002726 |
4 |
0.017
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.017
|
|
|
|
positive regulation of mitochondrion organization
|
GO:0010822 |
30 |
0.017
|
|
|
|
aging
|
GO:0007568 |
66 |
0.017
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.017
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.017
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.017
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.016
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.016
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.016
|
|
|
|
cerebral cortex radial glia guided migration
|
GO:0021801 |
1 |
0.016
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.016
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.016
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.016
|
|
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.016
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.016
|
Human |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.016
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.016
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.016
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.016
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.016
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.016
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.016
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.016
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.016
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.016
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.016
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.016
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.015
|
|
|
|
positive regulation of fibroblast growth factor receptor signaling pathway
|
GO:0045743 |
3 |
0.015
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.015
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.015
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.015
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.015
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.015
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.015
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
4 |
0.015
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.015
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.015
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.015
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.015
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.015
|
|
|
|
microtubule depolymerization
|
GO:0007019 |
18 |
0.015
|
|
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
4 |
0.015
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.015
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.015
|
Human |
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.015
|
|
|
|
regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031664 |
13 |
0.014
|
Human |
|
|
spermatid development
|
GO:0007286 |
4 |
0.014
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.014
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.014
|
Human |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.014
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.014
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.014
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.014
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.014
|
|
|
|
system process
|
GO:0003008 |
349 |
0.014
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
4 |
0.014
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.014
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.014
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
31 |
0.014
|
|
|
|
scf dependent proteasomal ubiquitin dependent protein catabolic process
|
GO:0031146 |
15 |
0.014
|
|
|
|
immunoglobulin secretion
|
GO:0048305 |
1 |
0.014
|
|
|
|
regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902108 |
18 |
0.014
|
|
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
18 |
0.014
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.014
|
|
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.014
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.014
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.014
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.014
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.014
|
|
|
|
chromatin assembly
|
GO:0031497 |
61 |
0.014
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.014
|
|
|
|
positive regulation of mitochondrial fission
|
GO:0090141 |
7 |
0.014
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.014
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.014
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.014
|
Human |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.013
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.013
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.013
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.013
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.013
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.013
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.013
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.013
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.013
|
|
|
|
embryonic hindlimb morphogenesis
|
GO:0035116 |
2 |
0.013
|
|
|
|
response to disaccharide
|
GO:0034285 |
1 |
0.013
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.013
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.013
|
Human |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.013
|
Human |
|
|
neuron development
|
GO:0048666 |
113 |
0.013
|
|
|
|
pharynx development
|
GO:0060465 |
1 |
0.013
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.013
|
|
