Mus musculus

61 known processes

Nampt

nicotinamide phosphoribosyltransferase

(Aliases: AI480535,Pbef1,NAmPRTase,Visfatin,AI314458,1110035O14Rik,Pbef)

Nampt biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
monocarboxylic acid metabolic process GO:0032787 191 0.342
regulation of mitochondrial fission GO:0090140 3 0.277
organonitrogen compound catabolic process GO:1901565 264 0.252
mitochondrion organization GO:0007005 134 0.150
cellular amino acid metabolic process GO:0006520 103 0.146
cellular lipid metabolic process GO:0044255 323 0.136
response to oxidative stress GO:0006979 123 0.128
nucleotide metabolic process GO:0009117 332 0.124
nucleoside phosphate metabolic process GO:0006753 338 0.124
heterocycle catabolic process GO:0046700 280 0.120
reactive oxygen species metabolic process GO:0072593 84 0.114
purine ribonucleotide catabolic process GO:0009154 208 0.102
amine metabolic process GO:0009308 45 0.096
nucleoside metabolic process GO:0009116 246 0.095
organic acid biosynthetic process GO:0016053 86 0.092
response to reactive oxygen species GO:0000302 56 0.087
cellular response to hormone stimulus GO:0032870 150 0.079
transmembrane transport GO:0055085 412 0.078
purine containing compound metabolic process GO:0072521 311 0.075
nucleobase containing small molecule metabolic process GO:0055086 352 0.075
cellular amine metabolic process GO:0044106 44 0.075
aromatic compound catabolic process GO:0019439 286 0.074
oxidation reduction process GO:0055114 342 0.074
apoptotic signaling pathway GO:0097190 306 0.073
organic cyclic compound catabolic process GO:1901361 295 0.072
regulation of hydrolase activity GO:0051336 246 0.072
purine nucleoside metabolic process GO:0042278 241 0.071
apoptotic mitochondrial changes GO:0008637 48 0.069
lipid transport GO:0006869 98 0.069
fatty acid metabolic process GO:0006631 121 0.067
negative regulation of cellular component organization GO:0051129 194 0.066
macromolecule catabolic process GO:0009057 281 0.064
response to inorganic substance GO:0010035 96 0.062
cytoplasmic transport GO:0016482 234 0.062
intracellular protein transport GO:0006886 204 0.061
cellular response to cytokine stimulus GO:0071345 189 0.060
regulation of secretion by cell GO:1903530 249 0.060
carbohydrate metabolic process GO:0005975 230 0.059
regulation of membrane potential GO:0042391 192 0.059
purine containing compound catabolic process GO:0072523 213 0.059
leukocyte differentiation GO:0002521 342 0.058
purine ribonucleoside catabolic process GO:0046130 205 0.058
lipid localization GO:0010876 126 0.058
membrane organization GO:0061024 245 0.058
ribose phosphate metabolic process GO:0019693 291 0.057
organophosphate catabolic process GO:0046434 232 0.057
response to organic cyclic compound GO:0014070 198 0.056
small molecule catabolic process GO:0044282 71 0.056
cellular macromolecule catabolic process GO:0044265 206 0.056
negative regulation of protein metabolic process GO:0051248 282 0.056
ribonucleoside metabolic process GO:0009119 245 0.056
cellular ketone metabolic process GO:0042180 84 0.054
mitochondrial transport GO:0006839 36 0.054
glycosyl compound metabolic process GO:1901657 246 0.054
fat cell differentiation GO:0045444 160 0.054
regulation of cellular ketone metabolic process GO:0010565 66 0.054
protein localization to organelle GO:0033365 185 0.053
negative regulation of intracellular signal transduction GO:1902532 167 0.053
ribonucleoside triphosphate metabolic process GO:0009199 220 0.053
glycerolipid metabolic process GO:0046486 122 0.051
purine nucleoside triphosphate metabolic process GO:0009144 226 0.050
response to peptide hormone GO:0043434 127 0.050
regulation of establishment of protein localization GO:0070201 181 0.049
purine ribonucleoside metabolic process GO:0046128 241 0.049
nucleoside phosphate catabolic process GO:1901292 222 0.048
positive regulation of hydrolase activity GO:0051345 148 0.048
homeostasis of number of cells GO:0048872 210 0.047
regulation of hormone levels GO:0010817 211 0.047
ribonucleoside catabolic process GO:0042454 206 0.046
protein catabolic process GO:0030163 221 0.046
cellular response to lipid GO:0071396 145 0.045
regulation of secretion GO:0051046 274 0.045
protein modification by small protein conjugation or removal GO:0070647 207 0.045
generation of precursor metabolites and energy GO:0006091 103 0.045
regulation of cellular catabolic process GO:0031329 242 0.044
response to peptide GO:1901652 136 0.043
regulation of apoptotic signaling pathway GO:2001233 197 0.042
cellular carbohydrate metabolic process GO:0044262 119 0.042
ion transmembrane transport GO:0034220 361 0.042
carboxylic acid biosynthetic process GO:0046394 86 0.041
cation homeostasis GO:0055080 212 0.041
purine ribonucleotide metabolic process GO:0009150 290 0.041
lipid biosynthetic process GO:0008610 179 0.041
cellular response to organonitrogen compound GO:0071417 145 0.040
protein processing GO:0016485 163 0.040
ras protein signal transduction GO:0007265 77 0.040
glycerophospholipid metabolic process GO:0006650 71 0.040
regulation of intracellular transport GO:0032386 159 0.040
establishment of protein localization to organelle GO:0072594 118 0.039
regulation of organelle organization GO:0033043 289 0.039
nucleoside triphosphate catabolic process GO:0009143 205 0.039
defense response to other organism GO:0098542 197 0.039
response to organonitrogen compound GO:0010243 246 0.039
cellular response to biotic stimulus GO:0071216 92 0.039
regulation of proteolysis GO:0030162 164 0.039
nitrogen compound transport GO:0071705 271 0.038
cellular nitrogen compound catabolic process GO:0044270 280 0.038
guanosine containing compound metabolic process GO:1901068 144 0.037
regulation of defense response GO:0031347 233 0.037
purine nucleotide catabolic process GO:0006195 211 0.037
cation transport GO:0006812 399 0.037
regulation of cell activation GO:0050865 289 0.037
protein maturation GO:0051604 176 0.035
innate immune response GO:0045087 157 0.035
positive regulation of cellular catabolic process GO:0031331 148 0.035
small molecule biosynthetic process GO:0044283 132 0.034
positive regulation of apoptotic process GO:0043065 217 0.034
cellular response to peptide hormone stimulus GO:0071375 92 0.034
dna metabolic process GO:0006259 303 0.034
regulation of protein transport GO:0051223 163 0.033
nucleotide catabolic process GO:0009166 217 0.033
ribonucleoside triphosphate catabolic process GO:0009203 199 0.033
regulation of lymphocyte activation GO:0051249 240 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.033
protein ubiquitination GO:0016567 171 0.032
purine nucleotide metabolic process GO:0006163 302 0.032
protein import GO:0017038 101 0.032
blood vessel morphogenesis GO:0048514 285 0.031
response to molecule of bacterial origin GO:0002237 143 0.031
positive regulation of programmed cell death GO:0043068 218 0.031
maintenance of location GO:0051235 89 0.031
protein modification by small protein conjugation GO:0032446 187 0.031
glucose homeostasis GO:0042593 128 0.031
negative regulation of organelle organization GO:0010639 90 0.030
multicellular organismal homeostasis GO:0048871 164 0.030
cellular response to oxidative stress GO:0034599 76 0.030
regulation of mitochondrion organization GO:0010821 27 0.030
immune effector process GO:0002252 321 0.030
alpha amino acid metabolic process GO:1901605 59 0.030
response to oxygen levels GO:0070482 62 0.029
peptidyl amino acid modification GO:0018193 336 0.029
cellular response to molecule of bacterial origin GO:0071219 83 0.029
neuron apoptotic process GO:0051402 142 0.029
response to nutrient levels GO:0031667 109 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.028
regulation of cell cycle GO:0051726 281 0.027
negative regulation of molecular function GO:0044092 258 0.027
organic anion transport GO:0015711 137 0.027
organic acid transport GO:0015849 101 0.027
purine nucleoside triphosphate catabolic process GO:0009146 203 0.027
release of cytochrome c from mitochondria GO:0001836 23 0.027
organic hydroxy compound metabolic process GO:1901615 203 0.027
regulation of protein kinase activity GO:0045859 232 0.027
sulfur compound metabolic process GO:0006790 100 0.027
protein targeting GO:0006605 143 0.027
regulation of ion transport GO:0043269 215 0.026
membrane fusion GO:0061025 38 0.026
ribonucleotide metabolic process GO:0009259 291 0.026
intrinsic apoptotic signaling pathway GO:0097193 132 0.026
regulation of lipid metabolic process GO:0019216 118 0.026
cytokine production GO:0001816 319 0.026
mapk cascade GO:0000165 281 0.026
lipid homeostasis GO:0055088 63 0.026
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.026
cellular homeostasis GO:0019725 240 0.026
organelle fusion GO:0048284 28 0.026
negative regulation of phosphorus metabolic process GO:0010563 184 0.026
regulation of cellular amine metabolic process GO:0033238 20 0.026
ribonucleoside monophosphate metabolic process GO:0009161 80 0.025
glycosyl compound catabolic process GO:1901658 206 0.025
establishment of vesicle localization GO:0051650 81 0.025
positive regulation of cell death GO:0010942 224 0.025
carbohydrate homeostasis GO:0033500 128 0.025
alcohol metabolic process GO:0006066 116 0.025
mitotic cell cycle GO:0000278 195 0.024
positive regulation of mitochondrion organization GO:0010822 17 0.024
regulation of protein localization GO:0032880 231 0.024
rhythmic process GO:0048511 174 0.024
striated muscle tissue development GO:0014706 293 0.024
nucleocytoplasmic transport GO:0006913 139 0.024
single organism nuclear import GO:1902593 95 0.024
regulation of reactive oxygen species metabolic process GO:2000377 40 0.024
neuron death GO:0070997 154 0.024
phospholipid metabolic process GO:0006644 87 0.024
carboxylic acid transport GO:0046942 100 0.024
regulation of cellular amino acid metabolic process GO:0006521 5 0.024
positive regulation of cellular amine metabolic process GO:0033240 5 0.024
metal ion homeostasis GO:0055065 189 0.024
b cell activation GO:0042113 161 0.024
regulation of carbohydrate metabolic process GO:0006109 75 0.023
nuclear transport GO:0051169 139 0.023
positive regulation of protein modification process GO:0031401 299 0.023
purine nucleoside catabolic process GO:0006152 205 0.023
myeloid cell differentiation GO:0030099 233 0.023
positive regulation of cell activation GO:0050867 158 0.023
regulation of cytokine production GO:0001817 266 0.023
protein oligomerization GO:0051259 67 0.023
negative regulation of apoptotic signaling pathway GO:2001234 104 0.023
gtp metabolic process GO:0046039 144 0.023
activation of innate immune response GO:0002218 56 0.023
steroid metabolic process GO:0008202 119 0.023
small gtpase mediated signal transduction GO:0007264 97 0.023
positive regulation of innate immune response GO:0045089 80 0.023
negative regulation of cell proliferation GO:0008285 296 0.023
skeletal system development GO:0001501 356 0.022
response to metal ion GO:0010038 47 0.022
regulation of purine nucleotide metabolic process GO:1900542 169 0.022
ossification GO:0001503 216 0.022
cellular response to lipopolysaccharide GO:0071222 77 0.022
organelle fission GO:0048285 170 0.022
regulation of nucleotide metabolic process GO:0006140 169 0.022
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.022
nucleoside triphosphate metabolic process GO:0009141 230 0.021
protein import into nucleus GO:0006606 95 0.021
regulation of response to wounding GO:1903034 189 0.021
response to growth factor GO:0070848 198 0.021
positive regulation of secretion GO:0051047 130 0.021
anion transport GO:0006820 177 0.021
angiogenesis GO:0001525 201 0.021
dendrite development GO:0016358 115 0.021
organic acid catabolic process GO:0016054 51 0.021
organic hydroxy compound transport GO:0015850 93 0.021
positive regulation of lymphocyte activation GO:0051251 140 0.021
regulation of peptidase activity GO:0052547 96 0.021
circulatory system process GO:0003013 197 0.021
g protein coupled receptor signaling pathway GO:0007186 243 0.021
acylglycerol metabolic process GO:0006639 55 0.021
regulation of body fluid levels GO:0050878 162 0.021
locomotory behavior GO:0007626 195 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.021
lipid catabolic process GO:0016042 69 0.021
regulation of nucleocytoplasmic transport GO:0046822 73 0.021
response to lipopolysaccharide GO:0032496 128 0.021
urogenital system development GO:0001655 261 0.020
regulation of neuron apoptotic process GO:0043523 122 0.020
myeloid leukocyte differentiation GO:0002573 119 0.020
amp metabolic process GO:0046033 4 0.020
transmission of nerve impulse GO:0019226 76 0.020
response to insulin GO:0032868 100 0.020
carbohydrate biosynthetic process GO:0016051 74 0.020
regulation of cellular component biogenesis GO:0044087 181 0.020
regulation of protein serine threonine kinase activity GO:0071900 157 0.020
regulation of kinase activity GO:0043549 249 0.020
negative regulation of cellular protein metabolic process GO:0032269 247 0.020
cofactor metabolic process GO:0051186 80 0.020
lateral inhibition GO:0046331 1 0.020
b cell differentiation GO:0030183 78 0.020
mitochondrial membrane organization GO:0007006 26 0.020
positive regulation of defense response GO:0031349 124 0.020
nuclear import GO:0051170 95 0.020
gtp catabolic process GO:0006184 143 0.020
amide transport GO:0042886 138 0.020
phosphatidylethanolamine metabolic process GO:0046337 2 0.020
cell type specific apoptotic process GO:0097285 268 0.020
endoplasmic reticulum tubular network organization GO:0071786 1 0.020
cellular response to peptide GO:1901653 92 0.020
lymphocyte proliferation GO:0046651 164 0.019
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.019
neuronal action potential GO:0019228 54 0.019
lymphocyte differentiation GO:0030098 242 0.019
regulation of mapk cascade GO:0043408 248 0.019
positive regulation of gtpase activity GO:0043547 85 0.019
inflammatory response GO:0006954 244 0.019
hexose metabolic process GO:0019318 98 0.019
mitochondrion distribution GO:0048311 4 0.019
monocarboxylic acid biosynthetic process GO:0072330 61 0.019
cellular response to insulin stimulus GO:0032869 78 0.019
action potential GO:0001508 78 0.019
organelle localization GO:0051640 179 0.019
cellular amide metabolic process GO:0043603 58 0.019
cellular protein catabolic process GO:0044257 155 0.019
regulation of endopeptidase activity GO:0052548 89 0.019
response to extracellular stimulus GO:0009991 127 0.019
regionalization GO:0003002 337 0.019
lymphocyte apoptotic process GO:0070227 54 0.019
divalent inorganic cation transport GO:0072511 178 0.019
regulation of nucleoside metabolic process GO:0009118 130 0.019
regulation of innate immune response GO:0045088 91 0.019
regulation of homeostatic process GO:0032844 182 0.019
cation transmembrane transport GO:0098655 266 0.018
positive regulation of t cell activation GO:0050870 101 0.018
germ cell development GO:0007281 185 0.018
regulation of cell motility GO:2000145 236 0.018
regulation of ras protein signal transduction GO:0046578 114 0.018
response to radiation GO:0009314 165 0.018
rho protein signal transduction GO:0007266 32 0.018
positive regulation of protein phosphorylation GO:0001934 242 0.018
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.018
hormone secretion GO:0046879 128 0.018
ribonucleotide catabolic process GO:0009261 208 0.018
sterol homeostasis GO:0055092 45 0.018
pyruvate metabolic process GO:0006090 28 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
cellular biogenic amine metabolic process GO:0006576 28 0.018
stem cell development GO:0048864 219 0.018
blood circulation GO:0008015 195 0.018
response to steroid hormone GO:0048545 56 0.017
hormone metabolic process GO:0042445 86 0.017
negative regulation of cellular amine metabolic process GO:0033239 1 0.017
cellular chemical homeostasis GO:0055082 215 0.017
atp metabolic process GO:0046034 75 0.017
wound healing GO:0042060 157 0.017
dephosphorylation GO:0016311 129 0.017
hypoxia inducible factor 1alpha signaling pathway GO:0097411 2 0.017
muscle tissue development GO:0060537 308 0.017
endomembrane system organization GO:0010256 147 0.017
leukocyte homeostasis GO:0001776 79 0.017
glycerolipid biosynthetic process GO:0045017 50 0.017
ensheathment of neurons GO:0007272 76 0.017
regulation of protein targeting GO:1903533 61 0.017
regulation of cell adhesion GO:0030155 154 0.017
male gamete generation GO:0048232 285 0.017
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
monocarboxylic acid transport GO:0015718 44 0.016
protein localization to nucleus GO:0034504 121 0.016
purine nucleoside monophosphate metabolic process GO:0009126 81 0.016
anatomical structure homeostasis GO:0060249 145 0.016
forebrain development GO:0030900 302 0.016
synaptic transmission GO:0007268 329 0.016
regulation of lymphocyte differentiation GO:0045619 107 0.016
chromatin organization GO:0006325 206 0.016
autophagy GO:0006914 45 0.016
renal system development GO:0072001 225 0.016
monosaccharide metabolic process GO:0005996 106 0.016
regulation of leukocyte differentiation GO:1902105 159 0.016
negative regulation of intracellular protein transport GO:0090317 27 0.016
regulation of leukocyte apoptotic process GO:2000106 56 0.016
copii coated vesicle budding GO:0090114 2 0.016
cellular response to inorganic substance GO:0071241 37 0.016
epithelium migration GO:0090132 63 0.016
negative regulation of hydrolase activity GO:0051346 71 0.016
gland development GO:0048732 330 0.016
multicellular organismal signaling GO:0035637 91 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
response to superoxide GO:0000303 16 0.016
tissue homeostasis GO:0001894 115 0.016
cellular lipid catabolic process GO:0044242 52 0.016
circadian regulation of gene expression GO:0032922 48 0.015
peptide metabolic process GO:0006518 46 0.015
regulation of protein localization to nucleus GO:1900180 60 0.015
cellular metal ion homeostasis GO:0006875 151 0.015
multi multicellular organism process GO:0044706 109 0.015
cellular modified amino acid metabolic process GO:0006575 63 0.015
heart morphogenesis GO:0003007 178 0.015
positive regulation of dna templated transcription elongation GO:0032786 2 0.015
monosaccharide biosynthetic process GO:0046364 44 0.015
positive regulation of nucleoside metabolic process GO:0045979 91 0.015
cellular response to organic cyclic compound GO:0071407 87 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.015
plasma membrane organization GO:0007009 90 0.015
regulation of cell migration GO:0030334 219 0.015
body fluid secretion GO:0007589 53 0.015
regulation of neuron differentiation GO:0045664 281 0.015
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.015
regulation of transferase activity GO:0051338 263 0.015
endocytosis GO:0006897 168 0.015
nuclear division GO:0000280 158 0.015
positive regulation of nucleotide metabolic process GO:0045981 114 0.015
negative regulation of protein modification process GO:0031400 163 0.015
regulation of fat cell differentiation GO:0045598 81 0.015
regulation of inflammatory response GO:0050727 147 0.015
cell aging GO:0007569 35 0.015
vesicle organization GO:0016050 60 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
regulation of purine nucleotide catabolic process GO:0033121 122 0.014
myeloid cell homeostasis GO:0002262 114 0.014
lymphocyte homeostasis GO:0002260 64 0.014
regulation of cysteine type endopeptidase activity GO:2000116 65 0.014
localization within membrane GO:0051668 4 0.014
pyruvate transport GO:0006848 2 0.014
regulation of release of cytochrome c from mitochondria GO:0090199 11 0.014
regulation of protein catabolic process GO:0042176 108 0.014
ubiquitin dependent protein catabolic process GO:0006511 129 0.014
regulation of transmembrane transport GO:0034762 128 0.014
lipid modification GO:0030258 65 0.014
response to oxygen radical GO:0000305 16 0.014
skeletal system morphogenesis GO:0048705 203 0.014
regulation of cellular response to growth factor stimulus GO:0090287 82 0.014
negative regulation of phosphorylation GO:0042326 166 0.014
regulation of nucleotide catabolic process GO:0030811 122 0.014
triglyceride metabolic process GO:0006641 51 0.014
inorganic cation transmembrane transport GO:0098662 207 0.014
cellular ion homeostasis GO:0006873 165 0.014
oxygen homeostasis GO:0032364 2 0.014
positive regulation of mapk cascade GO:0043410 170 0.014
cellular response to extracellular stimulus GO:0031668 81 0.014
positive regulation of ras gtpase activity GO:0032320 65 0.014
negative regulation of mitochondrion organization GO:0010823 9 0.013
regulation of vesicle mediated transport GO:0060627 139 0.013
negative regulation of protein maturation GO:1903318 79 0.013
gonad development GO:0008406 141 0.013
positive regulation of cell motility GO:2000147 116 0.013
fertilization GO:0009566 127 0.013
response to drug GO:0042493 75 0.013
sensory perception GO:0007600 245 0.013
regulation of removal of superoxide radicals GO:2000121 4 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
negative regulation of immune system process GO:0002683 209 0.013
positive regulation of secretion by cell GO:1903532 114 0.013
glucose transport GO:0015758 56 0.013
peptidyl tyrosine modification GO:0018212 145 0.013
spermatogenesis GO:0007283 284 0.013
regulation of neuron death GO:1901214 134 0.013
cell maturation GO:0048469 127 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.013
respiratory system development GO:0060541 190 0.013
glycoprotein metabolic process GO:0009100 116 0.013
regulation of multi organism process GO:0043900 111 0.013
nucleoside catabolic process GO:0009164 206 0.013
regulation of t cell activation GO:0050863 170 0.013
myelination GO:0042552 74 0.013
divalent metal ion transport GO:0070838 172 0.013
positive regulation of leukocyte differentiation GO:1902107 86 0.013
regulation of protein maturation GO:1903317 96 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
embryonic organ morphogenesis GO:0048562 276 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
regulation of neurotransmitter levels GO:0001505 87 0.012
response to starvation GO:0042594 65 0.012
misfolded protein transport GO:0070843 1 0.012
negative regulation of protein processing GO:0010955 79 0.012
positive regulation of kinase activity GO:0033674 155 0.012
epithelial cell proliferation GO:0050673 174 0.012
mitochondrion degradation GO:0000422 3 0.012
respiratory tube development GO:0030323 167 0.012
regulation of intracellular protein transport GO:0033157 82 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.012
phosphatidylethanolamine biosynthetic process GO:0006646 2 0.012
regulation of metal ion transport GO:0010959 106 0.012
regulation of cellular response to stress GO:0080135 159 0.012
gluconeogenesis GO:0006094 39 0.012
connective tissue development GO:0061448 179 0.012
cofactor biosynthetic process GO:0051188 41 0.012
tube formation GO:0035148 140 0.012
positive regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902110 11 0.012
cellular response to external stimulus GO:0071496 88 0.012
sterol transport GO:0015918 38 0.012
negative regulation of intracellular transport GO:0032387 38 0.012
regulation of gtp catabolic process GO:0033124 113 0.012
regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108 14 0.012
negative regulation of cell cycle GO:0045786 123 0.012
regulation of lipid biosynthetic process GO:0046890 54 0.012
positive regulation of cell cycle GO:0045787 92 0.012
fatty acid transport GO:0015908 28 0.012
multicellular organismal aging GO:0010259 24 0.012
proteasomal protein catabolic process GO:0010498 98 0.012
regulation of vacuole organization GO:0044088 4 0.012
positive regulation of hormone secretion GO:0046887 38 0.012
canonical wnt signaling pathway GO:0060070 130 0.012
cellular response to acid chemical GO:0071229 68 0.012
placenta development GO:0001890 140 0.011
positive regulation of cytokine production GO:0001819 174 0.011
response to hydrogen peroxide GO:0042542 32 0.011
regulation of protein complex assembly GO:0043254 83 0.011
regulation of system process GO:0044057 200 0.011
fatty acid biosynthetic process GO:0006633 41 0.011
calcium ion homeostasis GO:0055074 127 0.011
negative regulation of cytoplasmic transport GO:1903650 29 0.011
regulation of t cell differentiation GO:0045580 83 0.011
energy derivation by oxidation of organic compounds GO:0015980 77 0.011
carboxylic acid catabolic process GO:0046395 51 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
acetyl coa biosynthetic process from pyruvate GO:0006086 3 0.011
regulation of ras gtpase activity GO:0032318 88 0.011
positive regulation of thymocyte migration GO:2000412 2 0.011
endoplasmic reticulum organization GO:0007029 10 0.011
male sex differentiation GO:0046661 109 0.011
spermatid development GO:0007286 108 0.011
response to temperature stimulus GO:0009266 55 0.011
coenzyme metabolic process GO:0006732 52 0.011
positive regulation of protein kinase activity GO:0045860 144 0.011
stem cell differentiation GO:0048863 268 0.011
ameboidal type cell migration GO:0001667 128 0.011
neutral lipid metabolic process GO:0006638 57 0.011
negative regulation of endopeptidase activity GO:0010951 44 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
negative regulation of membrane potential GO:0045837 4 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.011
regulation of anatomical structure size GO:0090066 178 0.011
establishment of organelle localization GO:0051656 122 0.011
actin cytoskeleton organization GO:0030036 220 0.011
defense response to virus GO:0051607 68 0.011
protein homooligomerization GO:0051260 43 0.011
t cell activation GO:0042110 289 0.011
defense response to bacterium GO:0042742 119 0.011
leukocyte migration GO:0050900 124 0.011
negative regulation of neuron apoptotic process GO:0043524 92 0.011
lipid storage GO:0019915 36 0.011
organic hydroxy compound biosynthetic process GO:1901617 77 0.011
insulin secretion GO:0030073 89 0.011
long chain fatty acid metabolic process GO:0001676 26 0.011
female meiosis chromosome segregation GO:0016321 1 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011

Nampt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.063
inherited metabolic disorder DOID:655 0 0.063
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.030
sensory system disease DOID:0050155 0 0.019
eye and adnexa disease DOID:1492 0 0.019
amino acid metabolic disorder DOID:9252 0 0.018
eye disease DOID:5614 0 0.016
musculoskeletal system disease DOID:17 0 0.013
immune system disease DOID:2914 0 0.012
hematopoietic system disease DOID:74 0 0.012
connective tissue disease DOID:65 0 0.011