Mus musculus

0 known processes

Mier2

mesoderm induction early response 1, family member 2

(Aliases: 2700087H15Rik,mKIAA1193)

Mier2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation GO:0032446 187 0.179
macromolecule catabolic process GO:0009057 281 0.101
protein modification by small protein conjugation or removal GO:0070647 207 0.090
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.088
cellular response to dna damage stimulus GO:0006974 207 0.079
protein catabolic process GO:0030163 221 0.069
ribonucleoside catabolic process GO:0042454 206 0.067
chemotaxis GO:0006935 247 0.063
protein ubiquitination GO:0016567 171 0.063
organic cyclic compound catabolic process GO:1901361 295 0.062
regulation of cellular catabolic process GO:0031329 242 0.056
protein palmitoylation GO:0018345 14 0.054
dna metabolic process GO:0006259 303 0.054
carbohydrate metabolic process GO:0005975 230 0.054
compound eye development GO:0048749 1 0.054
regulation of nucleotide catabolic process GO:0030811 122 0.053
organonitrogen compound catabolic process GO:1901565 264 0.053
nucleotide metabolic process GO:0009117 332 0.052
regulation of neuron projection development GO:0010975 169 0.052
response to radiation GO:0009314 165 0.048
oocyte axis specification GO:0007309 2 0.048
germ cell development GO:0007281 185 0.048
regulation of nucleoside metabolic process GO:0009118 130 0.047
heterocycle catabolic process GO:0046700 280 0.046
purine nucleotide metabolic process GO:0006163 302 0.046
purine containing compound metabolic process GO:0072521 311 0.046
spermatogenesis GO:0007283 284 0.046
locomotory behavior GO:0007626 195 0.045
purine containing compound catabolic process GO:0072523 213 0.044
regulation of cellular ketone metabolic process GO:0010565 66 0.044
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.044
regulation of hydrolase activity GO:0051336 246 0.044
regulation of cellular amino acid metabolic process GO:0006521 5 0.043
spermatid differentiation GO:0048515 115 0.043
chromatin modification GO:0016568 187 0.043
positive regulation of cellular catabolic process GO:0031331 148 0.043
modification dependent protein catabolic process GO:0019941 133 0.042
cellular macromolecule catabolic process GO:0044265 206 0.041
histone modification GO:0016570 159 0.041
ribonucleoside triphosphate catabolic process GO:0009203 199 0.041
nucleobase containing small molecule metabolic process GO:0055086 352 0.041
nucleoside phosphate metabolic process GO:0006753 338 0.040
response to organonitrogen compound GO:0010243 246 0.040
modification dependent macromolecule catabolic process GO:0043632 133 0.040
guanosine containing compound metabolic process GO:1901068 144 0.039
actin cytoskeleton organization GO:0030036 220 0.039
ribonucleotide catabolic process GO:0009261 208 0.038
transmembrane transport GO:0055085 412 0.037
male gamete generation GO:0048232 285 0.037
organophosphate catabolic process GO:0046434 232 0.037
negative regulation of protein metabolic process GO:0051248 282 0.037
cellular nitrogen compound catabolic process GO:0044270 280 0.037
regulation of protein catabolic process GO:0042176 108 0.037
purine ribonucleotide metabolic process GO:0009150 290 0.036
positive regulation of nervous system development GO:0051962 221 0.036
purine ribonucleoside metabolic process GO:0046128 241 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
positive regulation of cell death GO:0010942 224 0.036
posttranscriptional regulation of gene expression GO:0010608 155 0.035
cell recognition GO:0008037 83 0.035
positive regulation of neuron differentiation GO:0045666 141 0.035
regulation of cell cycle GO:0051726 281 0.035
positive regulation of nucleotide catabolic process GO:0030813 88 0.034
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.034
positive regulation of apoptotic process GO:0043065 217 0.033
aromatic compound catabolic process GO:0019439 286 0.033
organonitrogen compound biosynthetic process GO:1901566 192 0.033
purine nucleoside metabolic process GO:0042278 241 0.032
intrinsic apoptotic signaling pathway GO:0097193 132 0.031
monosaccharide metabolic process GO:0005996 106 0.031
cellular protein catabolic process GO:0044257 155 0.030
ribonucleotide metabolic process GO:0009259 291 0.030
engulfment of apoptotic cell GO:0043652 3 0.030
negative regulation of lymphocyte activation GO:0051250 91 0.030
positive regulation of programmed cell death GO:0043068 218 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.030
asymmetric neuroblast division GO:0055059 1 0.030
negative regulation of cellular protein metabolic process GO:0032269 247 0.029
glycosyl compound metabolic process GO:1901657 246 0.029
ribonucleoside metabolic process GO:0009119 245 0.029
ribose phosphate metabolic process GO:0019693 291 0.029
ras protein signal transduction GO:0007265 77 0.029
negative regulation of cell projection organization GO:0031345 56 0.028
immune effector process GO:0002252 321 0.028
negative regulation of synapse assembly GO:0051964 3 0.028
regulation of homeostatic process GO:0032844 182 0.028
glycosyl compound catabolic process GO:1901658 206 0.027
gtp catabolic process GO:0006184 143 0.027
regulation of protein kinase activity GO:0045859 232 0.027
regulation of neuron differentiation GO:0045664 281 0.027
regulation of cellular amine metabolic process GO:0033238 20 0.027
negative regulation of immune system process GO:0002683 209 0.027
nucleotide catabolic process GO:0009166 217 0.026
positive regulation of cell development GO:0010720 237 0.026
cellular response to organonitrogen compound GO:0071417 145 0.026
dendrite development GO:0016358 115 0.026
nucleoside metabolic process GO:0009116 246 0.025
regulation of purine nucleotide metabolic process GO:1900542 169 0.025
guanosine containing compound catabolic process GO:1901069 144 0.025
mitotic cell cycle GO:0000278 195 0.025
amine metabolic process GO:0009308 45 0.025
methylation GO:0032259 134 0.024
female gamete generation GO:0007292 74 0.024
regulation of purine nucleotide catabolic process GO:0033121 122 0.024
regulation of neurotransmitter levels GO:0001505 87 0.024
ion transmembrane transport GO:0034220 361 0.024
asymmetric stem cell division GO:0098722 3 0.024
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
macromolecule methylation GO:0043414 120 0.023
lateral inhibition GO:0046331 1 0.023
positive regulation of cellular amine metabolic process GO:0033240 5 0.023
regulation of mitotic cell cycle GO:0007346 126 0.023
positive regulation of gtp catabolic process GO:0033126 85 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.023
small gtpase mediated signal transduction GO:0007264 97 0.023
cellular amino acid metabolic process GO:0006520 103 0.023
neuron death GO:0070997 154 0.022
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.022
insulin receptor signaling pathway GO:0008286 49 0.022
central nervous system neuron differentiation GO:0021953 162 0.022
regulation of ion transmembrane transport GO:0034765 119 0.022
gland development GO:0048732 330 0.022
regulation of binding GO:0051098 111 0.022
positive regulation of nucleotide metabolic process GO:0045981 114 0.022
gtp metabolic process GO:0046039 144 0.022
response to light stimulus GO:0009416 135 0.022
positive regulation of protein modification process GO:0031401 299 0.022
positive regulation of protein catabolic process GO:0045732 60 0.022
rho protein signal transduction GO:0007266 32 0.021
negative regulation of neuron projection development GO:0010977 50 0.021
purine nucleoside triphosphate catabolic process GO:0009146 203 0.021
negative regulation of molecular function GO:0044092 258 0.021
regulation of translation GO:0006417 71 0.021
oocyte construction GO:0007308 2 0.021
lymphocyte differentiation GO:0030098 242 0.021
apoptotic signaling pathway GO:0097190 306 0.021
regulation of cellular response to stress GO:0080135 159 0.021
microtubule based process GO:0007017 236 0.021
ribonucleoside triphosphate metabolic process GO:0009199 220 0.021
regulation of secretion by cell GO:1903530 249 0.021
neurotransmitter transport GO:0006836 76 0.021
protein methylation GO:0006479 81 0.021
stem cell differentiation GO:0048863 268 0.020
purine nucleotide catabolic process GO:0006195 211 0.020
negative regulation of cellular component organization GO:0051129 194 0.020
carbohydrate derivative catabolic process GO:1901136 231 0.020
mitotic cell cycle process GO:1903047 159 0.020
oxidation reduction process GO:0055114 342 0.020
cell division GO:0051301 120 0.020
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.020
spermatid development GO:0007286 108 0.020
nucleoside triphosphate metabolic process GO:0009141 230 0.020
purine ribonucleoside catabolic process GO:0046130 205 0.019
positive regulation of nucleoside metabolic process GO:0045979 91 0.019
positive regulation of hydrolase activity GO:0051345 148 0.019
circadian rhythm GO:0007623 114 0.019
purine nucleoside catabolic process GO:0006152 205 0.019
reactive oxygen species metabolic process GO:0072593 84 0.019
response to inorganic substance GO:0010035 96 0.019
developmental maturation GO:0021700 193 0.019
protein targeting GO:0006605 143 0.019
ubiquitin dependent protein catabolic process GO:0006511 129 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.019
homeostasis of number of cells GO:0048872 210 0.019
sensory perception of touch GO:0050975 2 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.018
small molecule biosynthetic process GO:0044283 132 0.018
connective tissue development GO:0061448 179 0.018
mapk cascade GO:0000165 281 0.018
synapse assembly GO:0007416 56 0.018
neuron projection guidance GO:0097485 141 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
response to insulin GO:0032868 100 0.017
cation transport GO:0006812 399 0.017
cation transmembrane transport GO:0098655 266 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.017
establishment of organelle localization GO:0051656 122 0.017
peptidyl amino acid modification GO:0018193 336 0.017
i kappab kinase nf kappab signaling GO:0007249 85 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
regulation of transferase activity GO:0051338 263 0.017
cognition GO:0050890 149 0.017
neurotransmitter secretion GO:0007269 62 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
regulation of ion transport GO:0043269 215 0.017
organophosphate biosynthetic process GO:0090407 122 0.017
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
regulation of cellular protein catabolic process GO:1903362 61 0.017
learning or memory GO:0007611 148 0.017
cell type specific apoptotic process GO:0097285 268 0.016
microtubule cytoskeleton organization GO:0000226 157 0.016
rna processing GO:0006396 105 0.016
hexose metabolic process GO:0019318 98 0.016
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
histone methylation GO:0016571 71 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
nuclear transport GO:0051169 139 0.016
multicellular organismal signaling GO:0035637 91 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
proteasomal protein catabolic process GO:0010498 98 0.016
lymphocyte mediated immunity GO:0002449 139 0.016
cellular homeostasis GO:0019725 240 0.016
bone development GO:0060348 120 0.015
peptidyl tyrosine modification GO:0018212 145 0.015
detection of external stimulus GO:0009581 61 0.015
protein import GO:0017038 101 0.015
learning GO:0007612 98 0.015
regulation of insulin receptor signaling pathway GO:0046626 21 0.015
cellular response to insulin stimulus GO:0032869 78 0.015
organelle fission GO:0048285 170 0.015
skeletal system morphogenesis GO:0048705 203 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
cellular response to peptide hormone stimulus GO:0071375 92 0.014
translation GO:0006412 93 0.014
peptidyl tyrosine phosphorylation GO:0018108 143 0.014
protein alkylation GO:0008213 81 0.014
positive regulation of transferase activity GO:0051347 167 0.014
multi multicellular organism process GO:0044706 109 0.014
cellular response to peptide GO:1901653 92 0.014
cytoplasmic transport GO:0016482 234 0.014
intracellular protein transport GO:0006886 204 0.014
cellular ketone metabolic process GO:0042180 84 0.014
regulation of cell cycle process GO:0010564 160 0.014
adaptive immune response GO:0002250 155 0.014
tube formation GO:0035148 140 0.014
stem cell proliferation GO:0072089 117 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
extracellular structure organization GO:0043062 148 0.014
response to peptide GO:1901652 136 0.014
regulation of protein kinase b signaling GO:0051896 56 0.014
negative regulation of protein modification process GO:0031400 163 0.014
sensory system development GO:0048880 3 0.014
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.014
covalent chromatin modification GO:0016569 163 0.014
dna repair GO:0006281 107 0.014
positive regulation of protein phosphorylation GO:0001934 242 0.014
sensory perception GO:0007600 245 0.013
single organism nuclear import GO:1902593 95 0.013
regulation of synapse structural plasticity GO:0051823 4 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
syncytium formation GO:0006949 43 0.013
nuclear import GO:0051170 95 0.013
glucose metabolic process GO:0006006 92 0.013
leukocyte differentiation GO:0002521 342 0.013
development of primary sexual characteristics GO:0045137 143 0.013
adult behavior GO:0030534 135 0.013
hindbrain development GO:0030902 128 0.013
striated muscle tissue development GO:0014706 293 0.013
positive regulation of apoptotic signaling pathway GO:2001235 95 0.013
divalent inorganic cation transport GO:0072511 178 0.013
cellularization GO:0007349 1 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
positive regulation of gtpase activity GO:0043547 85 0.013
regulation of protein localization GO:0032880 231 0.013
regulation of antimicrobial peptide production GO:0002784 1 0.013
regulation of cell shape GO:0008360 39 0.013
multicellular organism growth GO:0035264 161 0.013
nitrogen compound transport GO:0071705 271 0.013
regulation of kinase activity GO:0043549 249 0.013
establishment of protein localization to organelle GO:0072594 118 0.013
phagocytosis GO:0006909 66 0.013
organic acid biosynthetic process GO:0016053 86 0.013
retina development in camera type eye GO:0060041 119 0.013
cellular amine metabolic process GO:0044106 44 0.013
endocytosis GO:0006897 168 0.012
positive regulation of rho gtpase activity GO:0032321 41 0.012
regulation of secretion GO:0051046 274 0.012
synapse organization GO:0050808 125 0.012
myeloid cell differentiation GO:0030099 233 0.012
sulfur compound biosynthetic process GO:0044272 37 0.012
chromatin organization GO:0006325 206 0.012
skeletal system development GO:0001501 356 0.012
negative regulation of nervous system development GO:0051961 156 0.012
meiotic cell cycle GO:0051321 122 0.012
nucleoside catabolic process GO:0009164 206 0.012
regulation of mapk cascade GO:0043408 248 0.012
cellular response to lipid GO:0071396 145 0.012
lipid biosynthetic process GO:0008610 179 0.012
oogenesis GO:0048477 56 0.012
second messenger mediated signaling GO:0019932 73 0.012
regulation of cell size GO:0008361 72 0.012
neuron recognition GO:0008038 25 0.012
response to uv GO:0009411 44 0.012
calcium ion transport GO:0006816 159 0.012
regulation of organelle organization GO:0033043 289 0.012
defense response to other organism GO:0098542 197 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
response to oxidative stress GO:0006979 123 0.012
rhythmic process GO:0048511 174 0.012
maternal determination of anterior posterior axis embryo GO:0008358 2 0.012
positive regulation of proteolysis GO:0045862 85 0.012
single organismal cell cell adhesion GO:0016337 131 0.012
skeletal muscle organ development GO:0060538 163 0.012
regulation of proteolysis GO:0030162 164 0.012
glutamate receptor signaling pathway GO:0007215 35 0.012
regulation of t cell activation GO:0050863 170 0.012
response to peptide hormone GO:0043434 127 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.012
regulation of feeding behavior GO:0060259 3 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
inorganic cation transmembrane transport GO:0098662 207 0.011
cell adhesion GO:0007155 329 0.011
epithelial cell proliferation GO:0050673 174 0.011
regulation of rho gtpase activity GO:0032319 58 0.011
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.011
oocyte anterior posterior axis specification GO:0007314 2 0.011
single organism cell adhesion GO:0098602 156 0.011
muscle tissue development GO:0060537 308 0.011
regulation of response to wounding GO:1903034 189 0.011
vagus nerve morphogenesis GO:0021644 2 0.011
regulation of cell activation GO:0050865 289 0.011
carbohydrate biosynthetic process GO:0016051 74 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
negative regulation of phosphorus metabolic process GO:0010563 184 0.011
regulation of protein transport GO:0051223 163 0.011
axonogenesis GO:0007409 274 0.011
protein import into nucleus GO:0006606 95 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
positive regulation of growth GO:0045927 104 0.011
cellular lipid metabolic process GO:0044255 323 0.011
negative regulation of protein phosphorylation GO:0001933 126 0.011
regulation of cell projection organization GO:0031344 206 0.011
gonad development GO:0008406 141 0.011
cellular response to oxidative stress GO:0034599 76 0.011
mrna metabolic process GO:0016071 84 0.011
nuclear division GO:0000280 158 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
regulation of nucleocytoplasmic transport GO:0046822 73 0.011
wnt signaling pathway GO:0016055 188 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
skeletal muscle cell differentiation GO:0035914 66 0.011
trunk segmentation GO:0035290 4 0.010
neuron apoptotic process GO:0051402 142 0.010
positive regulation of kinase activity GO:0033674 155 0.010
camera type eye development GO:0043010 266 0.010
regulation of exocytosis GO:0017157 61 0.010
negative regulation of cell development GO:0010721 169 0.010
protein lipidation GO:0006497 28 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
regulation of neural retina development GO:0061074 3 0.010
regulation of neuron apoptotic process GO:0043523 122 0.010
negative regulation of cell activation GO:0050866 111 0.010
regulation of lipid metabolic process GO:0019216 118 0.010
peptide transport GO:0015833 133 0.010
regulation of glucose metabolic process GO:0010906 60 0.010
cytokine mediated signaling pathway GO:0019221 115 0.010
telencephalon development GO:0021537 186 0.010
dna dealkylation GO:0035510 11 0.010
regulation of heart contraction GO:0008016 77 0.010
embryonic organ morphogenesis GO:0048562 276 0.010

Mier2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
musculoskeletal system disease DOID:17 0 0.015