Mus musculus

0 known processes

Prepl

prolyl endopeptidase-like

(Aliases: D030028O16Rik,MGC7980,2810457N15Rik,mKIAA0436,9530014L06Rik)

Prepl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein catabolic process GO:0030163 221 0.108
nucleoside phosphate metabolic process GO:0006753 338 0.079
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.076
macromolecule catabolic process GO:0009057 281 0.075
glycosyl compound metabolic process GO:1901657 246 0.075
purine containing compound metabolic process GO:0072521 311 0.075
organonitrogen compound catabolic process GO:1901565 264 0.066
purine ribonucleotide metabolic process GO:0009150 290 0.064
ribose phosphate metabolic process GO:0019693 291 0.063
heterocycle catabolic process GO:0046700 280 0.063
nucleoside metabolic process GO:0009116 246 0.061
cellular amino acid metabolic process GO:0006520 103 0.061
cation transport GO:0006812 399 0.060
purine nucleoside metabolic process GO:0042278 241 0.059
nucleotide metabolic process GO:0009117 332 0.058
regulation of cellular amino acid metabolic process GO:0006521 5 0.057
nucleobase containing small molecule metabolic process GO:0055086 352 0.056
protein modification by small protein conjugation or removal GO:0070647 207 0.054
intracellular protein transport GO:0006886 204 0.053
ribonucleoside metabolic process GO:0009119 245 0.050
cellular ketone metabolic process GO:0042180 84 0.049
small gtpase mediated signal transduction GO:0007264 97 0.048
ribonucleotide metabolic process GO:0009259 291 0.048
organic cyclic compound catabolic process GO:1901361 295 0.046
purine ribonucleoside metabolic process GO:0046128 241 0.046
protein ubiquitination GO:0016567 171 0.046
transmembrane transport GO:0055085 412 0.046
positive regulation of cellular amine metabolic process GO:0033240 5 0.045
cellular amine metabolic process GO:0044106 44 0.045
pole plasm assembly GO:0007315 2 0.044
regulation of cellular ketone metabolic process GO:0010565 66 0.044
organelle localization GO:0051640 179 0.044
carbohydrate metabolic process GO:0005975 230 0.044
protein modification by small protein conjugation GO:0032446 187 0.043
purine nucleotide metabolic process GO:0006163 302 0.043
cellular protein catabolic process GO:0044257 155 0.042
glycosyl compound catabolic process GO:1901658 206 0.041
epithelial tube morphogenesis GO:0060562 303 0.040
cellular macromolecule catabolic process GO:0044265 206 0.040
membrane organization GO:0061024 245 0.040
regulation of establishment of protein localization GO:0070201 181 0.039
nucleoside triphosphate catabolic process GO:0009143 205 0.037
cellular nitrogen compound catabolic process GO:0044270 280 0.037
oxidation reduction process GO:0055114 342 0.036
amine metabolic process GO:0009308 45 0.036
establishment of organelle localization GO:0051656 122 0.036
nucleoside triphosphate metabolic process GO:0009141 230 0.036
carbohydrate derivative catabolic process GO:1901136 231 0.036
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
modification dependent macromolecule catabolic process GO:0043632 133 0.034
neural tube development GO:0021915 160 0.034
organelle assembly GO:0070925 177 0.034
purine nucleoside catabolic process GO:0006152 205 0.034
microtubule based process GO:0007017 236 0.034
embryonic epithelial tube formation GO:0001838 130 0.033
peptidyl amino acid modification GO:0018193 336 0.033
negative regulation of cellular component organization GO:0051129 194 0.033
modification dependent protein catabolic process GO:0019941 133 0.033
intracellular mrna localization GO:0008298 4 0.032
regulation of secretion by cell GO:1903530 249 0.032
male gamete generation GO:0048232 285 0.031
purine nucleoside triphosphate metabolic process GO:0009144 226 0.031
negative regulation of nervous system development GO:0051961 156 0.030
cation transmembrane transport GO:0098655 266 0.030
purine ribonucleotide catabolic process GO:0009154 208 0.030
purine containing compound catabolic process GO:0072523 213 0.030
nucleoside phosphate catabolic process GO:1901292 222 0.029
aromatic compound catabolic process GO:0019439 286 0.029
ribonucleoside triphosphate metabolic process GO:0009199 220 0.029
purine ribonucleoside catabolic process GO:0046130 205 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.029
response to organonitrogen compound GO:0010243 246 0.029
blood vessel morphogenesis GO:0048514 285 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.028
cytoskeleton dependent intracellular transport GO:0030705 50 0.028
regulation of membrane potential GO:0042391 192 0.028
nucleoside catabolic process GO:0009164 206 0.028
inorganic ion transmembrane transport GO:0098660 234 0.027
multicellular organism growth GO:0035264 161 0.027
ras protein signal transduction GO:0007265 77 0.027
synaptic transmission GO:0007268 329 0.027
cytoplasmic transport GO:0016482 234 0.027
atp metabolic process GO:0046034 75 0.027
olfactory learning GO:0008355 2 0.026
cellular response to growth factor stimulus GO:0071363 197 0.026
organophosphate catabolic process GO:0046434 232 0.026
ubiquitin dependent protein catabolic process GO:0006511 129 0.026
purine nucleoside triphosphate catabolic process GO:0009146 203 0.026
oocyte axis specification GO:0007309 2 0.026
regulation of protein localization GO:0032880 231 0.026
ribonucleoside catabolic process GO:0042454 206 0.025
sequestering of calcium ion GO:0051208 18 0.025
regulation of protein transport GO:0051223 163 0.025
regulation of transmembrane transport GO:0034762 128 0.025
oocyte construction GO:0007308 2 0.025
dephosphorylation GO:0016311 129 0.024
ion transmembrane transport GO:0034220 361 0.024
positive regulation of programmed cell death GO:0043068 218 0.024
regulation of cellular amine metabolic process GO:0033238 20 0.024
microtubule based movement GO:0007018 84 0.024
cognition GO:0050890 149 0.024
regulation of ion transmembrane transport GO:0034765 119 0.023
regulation of cellular component biogenesis GO:0044087 181 0.023
positive regulation of apoptotic process GO:0043065 217 0.023
cell type specific apoptotic process GO:0097285 268 0.023
oocyte anterior posterior axis specification GO:0007314 2 0.022
mitochondrion organization GO:0007005 134 0.022
morphogenesis of embryonic epithelium GO:0016331 159 0.022
purine nucleotide catabolic process GO:0006195 211 0.022
positive regulation of cell death GO:0010942 224 0.022
spermatogenesis GO:0007283 284 0.022
microtubule cytoskeleton organization GO:0000226 157 0.022
regulation of circadian sleep wake cycle GO:0042749 3 0.022
ribonucleoside triphosphate catabolic process GO:0009203 199 0.021
regulation of cellular catabolic process GO:0031329 242 0.021
tube formation GO:0035148 140 0.021
apoptotic signaling pathway GO:0097190 306 0.021
response to growth factor GO:0070848 198 0.021
regulation of intracellular transport GO:0032386 159 0.021
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.021
regulation of secretion GO:0051046 274 0.021
regulation of intracellular protein transport GO:0033157 82 0.020
dna repair GO:0006281 107 0.020
divalent inorganic cation transport GO:0072511 178 0.020
muscle cell differentiation GO:0042692 261 0.020
positive regulation of organelle organization GO:0010638 128 0.020
divalent metal ion transport GO:0070838 172 0.020
cellular protein complex assembly GO:0043623 116 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.020
primary neural tube formation GO:0014020 95 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
ribonucleoside monophosphate metabolic process GO:0009161 80 0.020
positive regulation of ion transport GO:0043270 65 0.020
nucleoside monophosphate metabolic process GO:0009123 85 0.020
axonogenesis GO:0007409 274 0.019
negative regulation of molecular function GO:0044092 258 0.019
regulation of organelle organization GO:0033043 289 0.019
cellular lipid metabolic process GO:0044255 323 0.019
ribonucleotide catabolic process GO:0009261 208 0.019
neural tube formation GO:0001841 108 0.019
positive regulation of cell development GO:0010720 237 0.019
regionalization GO:0003002 337 0.019
misfolded protein transport GO:0070843 1 0.018
learning or memory GO:0007611 148 0.018
regulation of transporter activity GO:0032409 57 0.018
microtubule based transport GO:0010970 50 0.018
regulation of neuron differentiation GO:0045664 281 0.018
negative regulation of cellular protein metabolic process GO:0032269 247 0.018
organelle fission GO:0048285 170 0.018
protein acylation GO:0043543 64 0.018
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.018
cellular homeostasis GO:0019725 240 0.018
cellular ion homeostasis GO:0006873 165 0.017
inorganic cation transmembrane transport GO:0098662 207 0.017
anatomical structure homeostasis GO:0060249 145 0.017
regulation of cell motility GO:2000145 236 0.017
forebrain development GO:0030900 302 0.017
glycerolipid metabolic process GO:0046486 122 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.017
purine nucleoside monophosphate metabolic process GO:0009126 81 0.017
maintenance of location GO:0051235 89 0.017
cellular component assembly involved in morphogenesis GO:0010927 139 0.017
neuron migration GO:0001764 122 0.017
response to endoplasmic reticulum stress GO:0034976 53 0.016
nucleotide catabolic process GO:0009166 217 0.016
engulfment of apoptotic cell GO:0043652 3 0.016
regulation of mitochondrial fission GO:0090140 3 0.016
telencephalon development GO:0021537 186 0.016
endomembrane system organization GO:0010256 147 0.016
establishment of mitochondrion localization GO:0051654 4 0.016
mrna metabolic process GO:0016071 84 0.016
mrna processing GO:0006397 63 0.016
neural tube closure GO:0001843 90 0.016
cellularization GO:0007349 1 0.016
chromatin modification GO:0016568 187 0.016
rna processing GO:0006396 105 0.016
proteasomal protein catabolic process GO:0010498 98 0.016
positive regulation of secretion by cell GO:1903532 114 0.016
epithelial tube formation GO:0072175 130 0.015
mitochondrion distribution GO:0048311 4 0.015
maternal determination of anterior posterior axis embryo GO:0008358 2 0.015
establishment of vesicle localization GO:0051650 81 0.015
synapse organization GO:0050808 125 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
carbohydrate homeostasis GO:0033500 128 0.015
cellular carbohydrate metabolic process GO:0044262 119 0.015
epithelial cell proliferation GO:0050673 174 0.015
muscle tissue development GO:0060537 308 0.015
fat cell differentiation GO:0045444 160 0.015
vesicle localization GO:0051648 86 0.015
developmental maturation GO:0021700 193 0.015
positive regulation of protein modification process GO:0031401 299 0.015
carbohydrate derivative biosynthetic process GO:1901137 183 0.015
metencephalon development GO:0022037 89 0.015
positive regulation of secretion GO:0051047 130 0.015
regulation of cell projection organization GO:0031344 206 0.014
mitotic cell cycle GO:0000278 195 0.014
action potential GO:0001508 78 0.014
smoothened signaling pathway GO:0007224 105 0.014
rho protein signal transduction GO:0007266 32 0.014
glucose homeostasis GO:0042593 128 0.014
regulation of hydrolase activity GO:0051336 246 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
synaptic vesicle localization GO:0097479 59 0.014
generation of precursor metabolites and energy GO:0006091 103 0.014
nitrogen compound transport GO:0071705 271 0.014
germ cell development GO:0007281 185 0.014
axon cargo transport GO:0008088 33 0.014
locomotory behavior GO:0007626 195 0.014
endocytosis GO:0006897 168 0.014
cation homeostasis GO:0055080 212 0.014
sulfur compound metabolic process GO:0006790 100 0.014
regulation of cell cycle GO:0051726 281 0.014
cell maturation GO:0048469 127 0.014
organonitrogen compound biosynthetic process GO:1901566 192 0.014
tube closure GO:0060606 91 0.014
cerebellum development GO:0021549 77 0.014
cellular chemical homeostasis GO:0055082 215 0.014
transmission of nerve impulse GO:0019226 76 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.014
spermatid development GO:0007286 108 0.014
negative regulation of cell development GO:0010721 169 0.014
protein localization to organelle GO:0033365 185 0.014
regulation of epithelial cell proliferation GO:0050678 141 0.013
regulation of ion transport GO:0043269 215 0.013
neuronal action potential GO:0019228 54 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
regulation of cell migration GO:0030334 219 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.013
protein complex disassembly GO:0043241 40 0.013
cellular protein complex disassembly GO:0043624 36 0.013
regulation of multi organism process GO:0043900 111 0.013
exocytosis GO:0006887 121 0.013
hindbrain development GO:0030902 128 0.013
regulation of cytokine production GO:0001817 266 0.013
multicellular organismal homeostasis GO:0048871 164 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
protein maturation GO:0051604 176 0.013
negative regulation of growth GO:0045926 99 0.013
chromatin organization GO:0006325 206 0.013
neuron neuron synaptic transmission GO:0007270 69 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.013
negative regulation of multi organism process GO:0043901 68 0.013
regulation of kinase activity GO:0043549 249 0.012
regulation of system process GO:0044057 200 0.012
regulation of ion transmembrane transporter activity GO:0032412 54 0.012
gland development GO:0048732 330 0.012
atp catabolic process GO:0006200 55 0.012
regulation of metal ion transport GO:0010959 106 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
organic hydroxy compound metabolic process GO:1901615 203 0.012
mitotic cell cycle process GO:1903047 159 0.012
cell adhesion GO:0007155 329 0.012
energy derivation by oxidation of organic compounds GO:0015980 77 0.012
covalent chromatin modification GO:0016569 163 0.012
camera type eye development GO:0043010 266 0.012
spermatid differentiation GO:0048515 115 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.012
small molecule catabolic process GO:0044282 71 0.012
sequestering of metal ion GO:0051238 19 0.012
digestive system development GO:0055123 200 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.012
cell division GO:0051301 120 0.012
protein localization to membrane GO:0072657 108 0.012
peptidyl lysine modification GO:0018205 77 0.012
monocarboxylic acid metabolic process GO:0032787 191 0.012
negative regulation of immune system process GO:0002683 209 0.012
myosin filament assembly GO:0031034 2 0.012
negative regulation of cell cycle GO:0045786 123 0.011
glycerophospholipid metabolic process GO:0006650 71 0.011
synaptic vesicle transport GO:0048489 57 0.011
neurotransmitter transport GO:0006836 76 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
regulation of vesicle mediated transport GO:0060627 139 0.011
purine nucleoside monophosphate catabolic process GO:0009128 58 0.011
calcium ion transport GO:0006816 159 0.011
regulation of purine nucleotide catabolic process GO:0033121 122 0.011
cellular response to dna damage stimulus GO:0006974 207 0.011
cellular amino acid catabolic process GO:0009063 25 0.011
nuclear division GO:0000280 158 0.011
mitochondrion transport along microtubule GO:0047497 3 0.011
regulation of homeostatic process GO:0032844 182 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
anion transport GO:0006820 177 0.011
negative regulation of cellular amine metabolic process GO:0033239 1 0.011
regulation of transferase activity GO:0051338 263 0.011
ribonucleoside monophosphate catabolic process GO:0009158 57 0.011
positive regulation of protein phosphorylation GO:0001934 242 0.011
positive regulation of intracellular transport GO:0032388 70 0.011
multicellular organismal signaling GO:0035637 91 0.011
immune effector process GO:0002252 321 0.011
mitotic cytokinesis GO:0000281 4 0.011
neuron apoptotic process GO:0051402 142 0.011
calcium ion transmembrane transport GO:0070588 85 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.011
response to peptide GO:1901652 136 0.011
regulation of proteolysis GO:0030162 164 0.011
protein depolymerization GO:0051261 34 0.011
chemotaxis GO:0006935 247 0.011
regulation of protein complex disassembly GO:0043244 28 0.011
regulation of protein processing GO:0070613 96 0.010
response to nutrient levels GO:0031667 109 0.010
peptidyl serine modification GO:0018209 83 0.010
negative regulation of protein phosphorylation GO:0001933 126 0.010
skeletal muscle organ development GO:0060538 163 0.010
negative regulation of protein modification process GO:0031400 163 0.010
tissue homeostasis GO:0001894 115 0.010
muscle system process GO:0003012 141 0.010
protein targeting GO:0006605 143 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
negative regulation of organelle organization GO:0010639 90 0.010
angiogenesis GO:0001525 201 0.010
carbohydrate biosynthetic process GO:0016051 74 0.010
cellular response to organonitrogen compound GO:0071417 145 0.010
sensory organ morphogenesis GO:0090596 242 0.010
nucleoside monophosphate catabolic process GO:0009125 59 0.010
cellular response to acid chemical GO:0071229 68 0.010
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.010
cellular metal ion homeostasis GO:0006875 151 0.010
homeostasis of number of cells GO:0048872 210 0.010
gtp catabolic process GO:0006184 143 0.010
regulation of neuron projection development GO:0010975 169 0.010
reactive oxygen species metabolic process GO:0072593 84 0.010

Prepl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.062
nervous system disease DOID:863 0 0.062
central nervous system disease DOID:331 0 0.022
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
neurodegenerative disease DOID:1289 0 0.014
musculoskeletal system disease DOID:17 0 0.010