Mus musculus

0 known processes

Usp4

ubiquitin specific peptidase 4 (proto-oncogene)

(Aliases: Unp,mKIAA4155,F730026I20Rik,KIAA4155)

Usp4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation GO:0032446 187 0.128
Human
protein modification by small protein conjugation or removal GO:0070647 207 0.094
Human
protein ubiquitination GO:0016567 171 0.084
Human
cellular amine metabolic process GO:0044106 44 0.062
amine metabolic process GO:0009308 45 0.061
regulation of cellular amine metabolic process GO:0033238 20 0.052
cellular amino acid metabolic process GO:0006520 103 0.052
spermatogenesis GO:0007283 284 0.049
regulation of cellular ketone metabolic process GO:0010565 66 0.045
regulation of cell projection organization GO:0031344 206 0.044
cellular ketone metabolic process GO:0042180 84 0.043
regulation of cellular amino acid metabolic process GO:0006521 5 0.042
negative regulation of molecular function GO:0044092 258 0.042
macromolecule catabolic process GO:0009057 281 0.042
nucleoside phosphate metabolic process GO:0006753 338 0.041
heterocycle catabolic process GO:0046700 280 0.041
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.040
male gamete generation GO:0048232 285 0.040
organic cyclic compound catabolic process GO:1901361 295 0.040
regulation of mapk cascade GO:0043408 248 0.039
microtubule based process GO:0007017 236 0.038
chromatin modification GO:0016568 187 0.038
positive regulation of cellular amine metabolic process GO:0033240 5 0.038
regulation of organelle organization GO:0033043 289 0.037
aromatic compound catabolic process GO:0019439 286 0.037
cation transport GO:0006812 399 0.036
purine nucleoside triphosphate catabolic process GO:0009146 203 0.036
modification dependent protein catabolic process GO:0019941 133 0.035
purine containing compound metabolic process GO:0072521 311 0.035
negative regulation of protein metabolic process GO:0051248 282 0.035
Human
regulation of neuron differentiation GO:0045664 281 0.035
purine nucleotide metabolic process GO:0006163 302 0.034
actin cytoskeleton organization GO:0030036 220 0.034
regulation of cellular component biogenesis GO:0044087 181 0.034
cellular nitrogen compound catabolic process GO:0044270 280 0.034
nucleobase containing small molecule metabolic process GO:0055086 352 0.033
ribonucleoside metabolic process GO:0009119 245 0.033
ribonucleoside triphosphate metabolic process GO:0009199 220 0.033
posttranscriptional regulation of gene expression GO:0010608 155 0.033
Human
ribose phosphate metabolic process GO:0019693 291 0.033
ribonucleotide metabolic process GO:0009259 291 0.032
nucleotide metabolic process GO:0009117 332 0.032
purine ribonucleotide metabolic process GO:0009150 290 0.032
cell type specific apoptotic process GO:0097285 268 0.031
nucleoside phosphate catabolic process GO:1901292 222 0.031
organonitrogen compound catabolic process GO:1901565 264 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.030
ribonucleoside triphosphate catabolic process GO:0009203 199 0.030
cellular chemical homeostasis GO:0055082 215 0.030
small gtpase mediated signal transduction GO:0007264 97 0.030
nucleoside triphosphate catabolic process GO:0009143 205 0.029
nucleotide catabolic process GO:0009166 217 0.029
purine ribonucleotide catabolic process GO:0009154 208 0.029
ubiquitin dependent protein catabolic process GO:0006511 129 0.029
membrane organization GO:0061024 245 0.029
regulation of neuron projection development GO:0010975 169 0.029
modification dependent macromolecule catabolic process GO:0043632 133 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.029
purine containing compound catabolic process GO:0072523 213 0.029
protein localization to organelle GO:0033365 185 0.028
regulation of cell cycle GO:0051726 281 0.028
purine nucleotide catabolic process GO:0006195 211 0.028
ras protein signal transduction GO:0007265 77 0.028
mapk cascade GO:0000165 281 0.028
nitrogen compound transport GO:0071705 271 0.028
negative regulation of cellular component organization GO:0051129 194 0.028
cellular lipid metabolic process GO:0044255 323 0.027
immune effector process GO:0002252 321 0.027
organelle localization GO:0051640 179 0.027
purine nucleoside metabolic process GO:0042278 241 0.026
cellular macromolecule catabolic process GO:0044265 206 0.026
peptidyl amino acid modification GO:0018193 336 0.026
protein catabolic process GO:0030163 221 0.026
organophosphate catabolic process GO:0046434 232 0.026
nucleoside metabolic process GO:0009116 246 0.026
protein processing GO:0016485 163 0.026
cell adhesion GO:0007155 329 0.026
dna metabolic process GO:0006259 303 0.025
endomembrane system organization GO:0010256 147 0.025
glycosyl compound metabolic process GO:1901657 246 0.025
dna repair GO:0006281 107 0.025
glycosyl compound catabolic process GO:1901658 206 0.025
muscle cell differentiation GO:0042692 261 0.025
nucleoside triphosphate metabolic process GO:0009141 230 0.024
purine ribonucleoside metabolic process GO:0046128 241 0.024
cation transmembrane transport GO:0098655 266 0.024
regulation of hydrolase activity GO:0051336 246 0.023
transmembrane transport GO:0055085 412 0.023
carbohydrate metabolic process GO:0005975 230 0.023
protein maturation GO:0051604 176 0.023
axonogenesis GO:0007409 274 0.023
positive regulation of protein phosphorylation GO:0001934 242 0.022
carbohydrate derivative catabolic process GO:1901136 231 0.022
purine ribonucleoside catabolic process GO:0046130 205 0.022
mitotic cell cycle GO:0000278 195 0.022
ribonucleotide catabolic process GO:0009261 208 0.022
regulation of transferase activity GO:0051338 263 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.021
apoptotic signaling pathway GO:0097190 306 0.021
cellular protein catabolic process GO:0044257 155 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
Human
regulation of protein localization GO:0032880 231 0.021
inorganic cation transmembrane transport GO:0098662 207 0.021
nucleoside catabolic process GO:0009164 206 0.021
cation homeostasis GO:0055080 212 0.021
negative regulation of cellular amine metabolic process GO:0033239 1 0.021
maintenance of location GO:0051235 89 0.021
inorganic ion transmembrane transport GO:0098660 234 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.021
endocytosis GO:0006897 168 0.020
positive regulation of protein modification process GO:0031401 299 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.020
mrna metabolic process GO:0016071 84 0.020
Human
positive regulation of cell development GO:0010720 237 0.020
dephosphorylation GO:0016311 129 0.020
cellular response to dna damage stimulus GO:0006974 207 0.020
cytoplasmic transport GO:0016482 234 0.020
intracellular protein transport GO:0006886 204 0.020
cell division GO:0051301 120 0.020
histone modification GO:0016570 159 0.020
cellular metal ion homeostasis GO:0006875 151 0.020
regulation of protein serine threonine kinase activity GO:0071900 157 0.020
metal ion homeostasis GO:0055065 189 0.020
regulation of cell activation GO:0050865 289 0.019
regulation of intracellular transport GO:0032386 159 0.019
establishment or maintenance of cell polarity GO:0007163 86 0.019
ribonucleoside catabolic process GO:0042454 206 0.019
organelle fission GO:0048285 170 0.019
cellular homeostasis GO:0019725 240 0.019
rna processing GO:0006396 105 0.019
Human
regulation of proteolysis GO:0030162 164 0.019
regulation of protein kinase activity GO:0045859 232 0.019
organic hydroxy compound metabolic process GO:1901615 203 0.019
negative regulation of organelle organization GO:0010639 90 0.019
multicellular organismal signaling GO:0035637 91 0.018
positive regulation of organelle organization GO:0010638 128 0.018
negative regulation of cell proliferation GO:0008285 296 0.018
response to organonitrogen compound GO:0010243 246 0.018
positive regulation of transferase activity GO:0051347 167 0.018
regulation of cellular component size GO:0032535 121 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.018
regulation of protein transport GO:0051223 163 0.018
multicellular organism growth GO:0035264 161 0.018
lymphocyte differentiation GO:0030098 242 0.018
positive regulation of cellular catabolic process GO:0031331 148 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
divalent inorganic cation transport GO:0072511 178 0.018
proteasomal protein catabolic process GO:0010498 98 0.017
glycoprotein metabolic process GO:0009100 116 0.017
positive regulation of nervous system development GO:0051962 221 0.017
skin development GO:0043588 220 0.017
regulation of kinase activity GO:0043549 249 0.017
vesicle organization GO:0016050 60 0.017
positive regulation of protein kinase activity GO:0045860 144 0.017
mitotic cell cycle process GO:1903047 159 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
ion transmembrane transport GO:0034220 361 0.017
divalent inorganic cation homeostasis GO:0072507 138 0.017
cellular response to cytokine stimulus GO:0071345 189 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
regulation of membrane potential GO:0042391 192 0.017
cellular ion homeostasis GO:0006873 165 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.017
neuron death GO:0070997 154 0.017
positive regulation of neuron differentiation GO:0045666 141 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
meiotic nuclear division GO:0007126 115 0.017
regulation of protein complex assembly GO:0043254 83 0.017
transmission of nerve impulse GO:0019226 76 0.017
locomotory behavior GO:0007626 195 0.016
retrograde transport endosome to golgi GO:0042147 2 0.016
regulation of map kinase activity GO:0043405 120 0.016
learning or memory GO:0007611 148 0.016
calcium ion transport GO:0006816 159 0.016
response to light stimulus GO:0009416 135 0.016
regulation of body fluid levels GO:0050878 162 0.016
regulation of neuron death GO:1901214 134 0.016
chromatin organization GO:0006325 206 0.016
positive regulation of mapk cascade GO:0043410 170 0.016
muscle cell development GO:0055001 133 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
positive regulation of kinase activity GO:0033674 155 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
regulation of lymphocyte activation GO:0051249 240 0.016
neuron apoptotic process GO:0051402 142 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
development of primary sexual characteristics GO:0045137 143 0.016
negative regulation of phosphorylation GO:0042326 166 0.016
neuronal action potential GO:0019228 54 0.016
cellular protein complex assembly GO:0043623 116 0.016
protein polyubiquitination GO:0000209 33 0.016
regulation of response to wounding GO:1903034 189 0.015
regulation of cytokine production GO:0001817 266 0.015
cognition GO:0050890 149 0.015
negative regulation of cell development GO:0010721 169 0.015
oxidation reduction process GO:0055114 342 0.015
sensory perception GO:0007600 245 0.015
skeletal system development GO:0001501 356 0.015
positive regulation of cell death GO:0010942 224 0.015
meiotic cell cycle GO:0051321 122 0.015
gland development GO:0048732 330 0.015
glycoprotein biosynthetic process GO:0009101 89 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
sensory organ morphogenesis GO:0090596 242 0.015
action potential GO:0001508 78 0.015
mitotic cytokinesis GO:0000281 4 0.015
calcium ion homeostasis GO:0055074 127 0.015
macromolecule glycosylation GO:0043413 55 0.015
response to growth factor GO:0070848 198 0.015
regulation of metal ion transport GO:0010959 106 0.015
regulation of vesicle mediated transport GO:0060627 139 0.015
covalent chromatin modification GO:0016569 163 0.015
regulation of defense response GO:0031347 233 0.015
dendrite development GO:0016358 115 0.015
cytokine production GO:0001816 319 0.015
regulation of secretion by cell GO:1903530 249 0.015
microtubule based movement GO:0007018 84 0.015
divalent metal ion transport GO:0070838 172 0.015
homeostasis of number of cells GO:0048872 210 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
cytokinetic process GO:0032506 2 0.015
olfactory learning GO:0008355 2 0.014
sequestering of calcium ion GO:0051208 18 0.014
regulation of purine nucleotide catabolic process GO:0033121 122 0.014
regulation of purine nucleotide metabolic process GO:1900542 169 0.014
negative regulation of nervous system development GO:0051961 156 0.014
response to radiation GO:0009314 165 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
regulation of protein maturation GO:1903317 96 0.014
anatomical structure homeostasis GO:0060249 145 0.014
negative regulation of immune system process GO:0002683 209 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
regulation of chromosome organization GO:0033044 83 0.014
regulation of neuron apoptotic process GO:0043523 122 0.014
lipid biosynthetic process GO:0008610 179 0.014
regulation of homeostatic process GO:0032844 182 0.014
regulation of anatomical structure size GO:0090066 178 0.014
leukocyte differentiation GO:0002521 342 0.014
epidermis development GO:0008544 187 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
cell junction organization GO:0034330 77 0.013
positive regulation of neuron projection development GO:0010976 79 0.013
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.013
cellular calcium ion homeostasis GO:0006874 119 0.013
germ cell development GO:0007281 185 0.013
small molecule biosynthetic process GO:0044283 132 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
regulation of secretion GO:0051046 274 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
regulation of protein catabolic process GO:0042176 108 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
protein localization to nucleus GO:0034504 121 0.013
spermatid development GO:0007286 108 0.013
response to molecule of bacterial origin GO:0002237 143 0.013
synapse organization GO:0050808 125 0.013
inflammatory response GO:0006954 244 0.013
regulation of endocytosis GO:0030100 69 0.013
oocyte axis specification GO:0007309 2 0.013
regulation of cell cycle process GO:0010564 160 0.013
nuclear division GO:0000280 158 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
response to lipopolysaccharide GO:0032496 128 0.013
cellular response to peptide GO:1901653 92 0.013
asymmetric stem cell division GO:0098722 3 0.013
negative regulation of intracellular signal transduction GO:1902532 167 0.013
compound eye development GO:0048749 1 0.013
establishment of organelle localization GO:0051656 122 0.013
regulation of ion transport GO:0043269 215 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
stem cell differentiation GO:0048863 268 0.013
adult behavior GO:0030534 135 0.012
glycerolipid metabolic process GO:0046486 122 0.012
asymmetric neuroblast division GO:0055059 1 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
rhythmic process GO:0048511 174 0.012
guanosine containing compound catabolic process GO:1901069 144 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
positive regulation of cell projection organization GO:0031346 95 0.012
actin polymerization or depolymerization GO:0008154 54 0.012
central nervous system neuron differentiation GO:0021953 162 0.012
spermatid differentiation GO:0048515 115 0.012
digestive system development GO:0055123 200 0.012
regulation of protein processing GO:0070613 96 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
negative regulation of protein processing GO:0010955 79 0.012
reactive nitrogen species metabolic process GO:2001057 0 0.012
innate immune response GO:0045087 157 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
epithelial tube morphogenesis GO:0060562 303 0.012
tissue homeostasis GO:0001894 115 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
neural precursor cell proliferation GO:0061351 121 0.012
forebrain development GO:0030900 302 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
regulation of hormone levels GO:0010817 211 0.012
negative regulation of proteolysis GO:0045861 74 0.012
inclusion body assembly GO:0070841 3 0.012
response to inorganic substance GO:0010035 96 0.012
nucleoside monophosphate catabolic process GO:0009125 59 0.012
negative regulation of protein maturation GO:1903318 79 0.012
negative regulation of synapse assembly GO:0051964 3 0.012
immune response regulating signaling pathway GO:0002764 125 0.012
epithelial cell development GO:0002064 159 0.012
regulation of cell motility GO:2000145 236 0.012
actin filament organization GO:0007015 113 0.012
cytoskeleton dependent intracellular transport GO:0030705 50 0.012
blood vessel morphogenesis GO:0048514 285 0.012
activation of immune response GO:0002253 138 0.012
single organism cell adhesion GO:0098602 156 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
developmental maturation GO:0021700 193 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
protein glycosylation GO:0006486 55 0.011
protein polymerization GO:0051258 57 0.011
positive regulation of map kinase activity GO:0043406 84 0.011
gonad development GO:0008406 141 0.011
purine nucleoside monophosphate catabolic process GO:0009128 58 0.011
reactive oxygen species metabolic process GO:0072593 84 0.011
response to insulin GO:0032868 100 0.011
cell activation involved in immune response GO:0002263 126 0.011
sensory system development GO:0048880 3 0.011
atp metabolic process GO:0046034 75 0.011
monocarboxylic acid metabolic process GO:0032787 191 0.011
camera type eye development GO:0043010 266 0.011
telencephalon development GO:0021537 186 0.011
response to peptide hormone GO:0043434 127 0.011
organelle assembly GO:0070925 177 0.011
cellular response to lipid GO:0071396 145 0.011
circulatory system process GO:0003013 197 0.011
lateral inhibition GO:0046331 1 0.011
golgi vesicle transport GO:0048193 30 0.011
glucose homeostasis GO:0042593 128 0.011
regulation of cell migration GO:0030334 219 0.011
blastocyst development GO:0001824 80 0.011
response to peptide GO:1901652 136 0.011
negative regulation of protein modification process GO:0031400 163 0.011
Human
t cell activation GO:0042110 289 0.011
protein localization to plasma membrane GO:0072659 57 0.011
regulation of t cell activation GO:0050863 170 0.011
synaptic transmission GO:0007268 329 0.011
respiratory system development GO:0060541 190 0.011
striated muscle tissue development GO:0014706 293 0.011
Mouse
neuron migration GO:0001764 122 0.011
sodium ion transport GO:0006814 73 0.011
lymphocyte proliferation GO:0046651 164 0.011
cell growth GO:0016049 130 0.011
regulation of cytoplasmic transport GO:1903649 112 0.011
cellularization GO:0007349 1 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.011
digestive tract development GO:0048565 190 0.011
amide transport GO:0042886 138 0.011
fertilization GO:0009566 127 0.011
alcohol metabolic process GO:0006066 116 0.010
regulation of cell growth GO:0001558 91 0.010
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.010
regulation of endopeptidase activity GO:0052548 89 0.010
positive regulation of dna templated transcription elongation GO:0032786 2 0.010
regulation of cellular response to stress GO:0080135 159 0.010
cellular component assembly involved in morphogenesis GO:0010927 139 0.010
fatty acid metabolic process GO:0006631 121 0.010
stem cell development GO:0048864 219 0.010
response to acid chemical GO:0001101 111 0.010
leukocyte activation involved in immune response GO:0002366 126 0.010
regulation of system process GO:0044057 200 0.010
peptidyl tyrosine modification GO:0018212 145 0.010
translation GO:0006412 93 0.010
ribonucleoside monophosphate catabolic process GO:0009158 57 0.010
regulation of translation GO:0006417 71 0.010
axon cargo transport GO:0008088 33 0.010
cellular response to peptide hormone stimulus GO:0071375 92 0.010
nuclear transport GO:0051169 139 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
skeletal muscle organ development GO:0060538 163 0.010
Mouse
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.010
positive regulation of secretion by cell GO:1903532 114 0.010

Usp4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
nervous system disease DOID:863 0 0.039
muscular disease DOID:0080000 0 0.021
musculoskeletal system disease DOID:17 0 0.021
neuropathy DOID:870 0 0.018
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
cardiovascular system disease DOID:1287 0 0.014
central nervous system disease DOID:331 0 0.014
muscle tissue disease DOID:66 0 0.014
myopathy DOID:423 0 0.012
disease of metabolism DOID:0014667 0 0.012
sensory system disease DOID:0050155 0 0.012
immune system disease DOID:2914 0 0.011
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010