Mus musculus

0 known processes

Usp5

ubiquitin specific peptidase 5 (isopeptidase T)

(Aliases: AA407472,Ucht,ISOT,ISOT-1)

Usp5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 329 0.288
ras protein signal transduction GO:0007265 77 0.204
chromatin modification GO:0016568 187 0.149
microtubule cytoskeleton organization GO:0000226 157 0.149
mitotic cell cycle GO:0000278 195 0.113
purine nucleoside triphosphate catabolic process GO:0009146 203 0.105
negative regulation of synapse assembly GO:0051964 3 0.105
macroautophagy GO:0016236 21 0.091
regulation of cell cycle GO:0051726 281 0.087
protein modification by small protein conjugation GO:0032446 187 0.085
purine ribonucleotide metabolic process GO:0009150 290 0.084
regulation of proteolysis GO:0030162 164 0.081
Human
chromatin organization GO:0006325 206 0.075
small gtpase mediated signal transduction GO:0007264 97 0.073
gtp catabolic process GO:0006184 143 0.070
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.065
protein maturation GO:0051604 176 0.064
histone modification GO:0016570 159 0.056
compound eye development GO:0048749 1 0.056
macromolecule catabolic process GO:0009057 281 0.054
Human Yeast Fly
purine containing compound metabolic process GO:0072521 311 0.052
carbohydrate derivative biosynthetic process GO:1901137 183 0.052
ribonucleoside triphosphate catabolic process GO:0009203 199 0.051
cytoplasmic transport GO:0016482 234 0.049
regulation of secretion GO:0051046 274 0.048
regulation of cell projection organization GO:0031344 206 0.048
nucleobase containing small molecule metabolic process GO:0055086 352 0.048
regulation of establishment of protein localization GO:0070201 181 0.048
microtubule based process GO:0007017 236 0.048
nucleoside triphosphate catabolic process GO:0009143 205 0.047
axonogenesis GO:0007409 274 0.046
intracellular protein transport GO:0006886 204 0.046
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.046
regulation of protein localization GO:0032880 231 0.045
purine nucleoside catabolic process GO:0006152 205 0.045
aromatic compound catabolic process GO:0019439 286 0.044
nucleotide catabolic process GO:0009166 217 0.044
rho protein signal transduction GO:0007266 32 0.043
olfactory learning GO:0008355 2 0.043
organelle localization GO:0051640 179 0.041
protein targeting GO:0006605 143 0.041
vesicle localization GO:0051648 86 0.040
nucleoside triphosphate metabolic process GO:0009141 230 0.040
protein ubiquitination GO:0016567 171 0.040
nucleotide metabolic process GO:0009117 332 0.040
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.040
regulation of neuron differentiation GO:0045664 281 0.039
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.039
organonitrogen compound catabolic process GO:1901565 264 0.039
ribonucleotide metabolic process GO:0009259 291 0.039
smoothened signaling pathway GO:0007224 105 0.038
nucleoside catabolic process GO:0009164 206 0.038
positive regulation of secretion GO:0051047 130 0.038
organophosphate catabolic process GO:0046434 232 0.038
skin development GO:0043588 220 0.037
nuclear export GO:0051168 34 0.037
rna interference GO:0016246 2 0.037
regulation of cellular component biogenesis GO:0044087 181 0.036
purine ribonucleoside catabolic process GO:0046130 205 0.036
cellular amine metabolic process GO:0044106 44 0.036
positive regulation of programmed cell death GO:0043068 218 0.036
purine containing compound catabolic process GO:0072523 213 0.034
covalent chromatin modification GO:0016569 163 0.034
activation of adenylate cyclase activity GO:0007190 4 0.034
guanosine containing compound catabolic process GO:1901069 144 0.033
carbohydrate metabolic process GO:0005975 230 0.033
Yeast
heterocycle catabolic process GO:0046700 280 0.033
nuclear division GO:0000280 158 0.032
cellular ketone metabolic process GO:0042180 84 0.032
Yeast
negative regulation of cellular component organization GO:0051129 194 0.032
regulation of cellular catabolic process GO:0031329 242 0.032
Human
ribonucleoside metabolic process GO:0009119 245 0.032
regulation of nucleotide metabolic process GO:0006140 169 0.032
posttranscriptional regulation of gene expression GO:0010608 155 0.031
positive regulation of nervous system development GO:0051962 221 0.031
positive regulation of cell development GO:0010720 237 0.031
transmembrane transport GO:0055085 412 0.031
ribonucleotide catabolic process GO:0009261 208 0.030
leukocyte differentiation GO:0002521 342 0.030
response to inorganic substance GO:0010035 96 0.030
protein modification by small protein conjugation or removal GO:0070647 207 0.030
Human Fly
purine nucleoside triphosphate metabolic process GO:0009144 226 0.030
clathrin coat assembly GO:0048268 2 0.029
cellular response to misfolded protein GO:0071218 5 0.029
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.029
Human
cation transport GO:0006812 399 0.028
purine ribonucleotide catabolic process GO:0009154 208 0.028
ribose phosphate metabolic process GO:0019693 291 0.028
habituation GO:0046959 3 0.028
membrane organization GO:0061024 245 0.028
ribonucleoside catabolic process GO:0042454 206 0.027
neural tube development GO:0021915 160 0.027
regulation of protein transport GO:0051223 163 0.027
negative regulation of phosphorus metabolic process GO:0010563 184 0.027
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.027
regulation of secretion by cell GO:1903530 249 0.027
lymphocyte differentiation GO:0030098 242 0.027
nucleoside phosphate catabolic process GO:1901292 222 0.027
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
protein export from nucleus GO:0006611 20 0.027
regulation of ras protein signal transduction GO:0046578 114 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.026
chemotaxis GO:0006935 247 0.026
guanosine containing compound metabolic process GO:1901068 144 0.026
regulation of purine nucleotide catabolic process GO:0033121 122 0.026
positive regulation of cell death GO:0010942 224 0.025
purine ribonucleoside metabolic process GO:0046128 241 0.025
positive regulation of secretion by cell GO:1903532 114 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
regulation of cellular amine metabolic process GO:0033238 20 0.024
organelle fission GO:0048285 170 0.024
germ cell development GO:0007281 185 0.024
melanosome localization GO:0032400 12 0.024
ribonucleoside triphosphate metabolic process GO:0009199 220 0.024
establishment of protein localization to organelle GO:0072594 118 0.024
thermosensory behavior GO:0040040 1 0.024
cognition GO:0050890 149 0.024
maintenance of location GO:0051235 89 0.023
positive regulation of gtp catabolic process GO:0033126 85 0.023
regulation of hormone levels GO:0010817 211 0.023
gtp metabolic process GO:0046039 144 0.023
modification dependent protein catabolic process GO:0019941 133 0.023
Human Yeast Fly
protein processing GO:0016485 163 0.022
multi multicellular organism process GO:0044706 109 0.022
positive regulation of hydrolase activity GO:0051345 148 0.022
regulation of nucleotide catabolic process GO:0030811 122 0.022
cellular amino acid metabolic process GO:0006520 103 0.022
misfolded protein transport GO:0070843 1 0.022
response to radiation GO:0009314 165 0.022
mitotic nuclear division GO:0007067 48 0.021
meiotic nuclear division GO:0007126 115 0.021
chromatin remodeling GO:0006338 32 0.021
protein localization to membrane GO:0072657 108 0.021
response to organonitrogen compound GO:0010243 246 0.021
regulation of protein maturation GO:1903317 96 0.021
multi organism behavior GO:0051705 62 0.021
positive regulation of neuron differentiation GO:0045666 141 0.021
purine nucleotide metabolic process GO:0006163 302 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.020
positive regulation of protein modification process GO:0031401 299 0.020
generation of precursor metabolites and energy GO:0006091 103 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.020
cellular response to nutrient levels GO:0031669 64 0.020
protein localization to organelle GO:0033365 185 0.020
purine nucleoside metabolic process GO:0042278 241 0.019
sensory perception GO:0007600 245 0.019
glucose homeostasis GO:0042593 128 0.019
regulation of cytoplasmic transport GO:1903649 112 0.019
regulation of cell cycle process GO:0010564 160 0.019
oocyte axis specification GO:0007309 2 0.019
regulation of cellular protein catabolic process GO:1903362 61 0.019
Human
regulation of organelle organization GO:0033043 289 0.019
regulation of synaptic plasticity GO:0048167 87 0.019
positive regulation of protein phosphorylation GO:0001934 242 0.019
spermatogenesis GO:0007283 284 0.018
axon guidance GO:0007411 141 0.018
protein catabolic process GO:0030163 221 0.018
Human Yeast Fly
negative regulation of hydrolase activity GO:0051346 71 0.018
learning or memory GO:0007611 148 0.018
melanosome transport GO:0032402 11 0.018
regulation of cellular ketone metabolic process GO:0010565 66 0.018
Yeast
purine nucleotide catabolic process GO:0006195 211 0.017
gene silencing GO:0016458 38 0.017
cell fate commitment GO:0045165 210 0.017
carbohydrate homeostasis GO:0033500 128 0.017
cellular macromolecule catabolic process GO:0044265 206 0.017
Human Yeast Fly
regulation of ion transport GO:0043269 215 0.017
dendrite development GO:0016358 115 0.017
fatty acid transmembrane transport GO:1902001 1 0.017
male gamete generation GO:0048232 285 0.017
photoreceptor cell differentiation GO:0046530 52 0.017
protein secretion GO:0009306 111 0.016
establishment of vesicle localization GO:0051650 81 0.016
amine metabolic process GO:0009308 45 0.016
learning GO:0007612 98 0.016
neuron projection guidance GO:0097485 141 0.016
positive regulation of gtpase activity GO:0043547 85 0.016
receptor biosynthetic process GO:0032800 3 0.016
negative regulation of molecular function GO:0044092 258 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.016
Human Yeast Fly
spermatid development GO:0007286 108 0.016
response to organic cyclic compound GO:0014070 198 0.016
sensory system development GO:0048880 3 0.016
regulation of cellular amino acid metabolic process GO:0006521 5 0.016
glycosyl compound catabolic process GO:1901658 206 0.015
regulation of intracellular transport GO:0032386 159 0.015
regulation of mitotic cell cycle GO:0007346 126 0.015
organic cyclic compound catabolic process GO:1901361 295 0.015
positive regulation of cellular catabolic process GO:0031331 148 0.015
Human
sodium ion transport GO:0006814 73 0.015
nucleoside phosphate metabolic process GO:0006753 338 0.015
response to endoplasmic reticulum stress GO:0034976 53 0.015
translation GO:0006412 93 0.015
regulation of cell motility GO:2000145 236 0.015
anion transport GO:0006820 177 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.015
oocyte construction GO:0007308 2 0.015
neurotransmitter transport GO:0006836 76 0.014
positive regulation of transferase activity GO:0051347 167 0.014
jnk cascade GO:0007254 72 0.014
regulation of hydrolase activity GO:0051336 246 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.014
Human Yeast Fly
reproductive behavior GO:0019098 32 0.014
response to light stimulus GO:0009416 135 0.014
small molecule catabolic process GO:0044282 71 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.014
negative regulation of protein maturation GO:1903318 79 0.014
spermatid differentiation GO:0048515 115 0.014
cell growth GO:0016049 130 0.014
retina morphogenesis in camera type eye GO:0060042 45 0.014
retina development in camera type eye GO:0060041 119 0.014
eye photoreceptor cell differentiation GO:0001754 41 0.014
t helper 2 cell cytokine production GO:0035745 4 0.014
regulation of peptide secretion GO:0002791 77 0.014
hormone metabolic process GO:0042445 86 0.013
sensory organ morphogenesis GO:0090596 242 0.013
locomotory behavior GO:0007626 195 0.013
negative regulation of neuron apoptotic process GO:0043524 92 0.013
positive regulation of apoptotic process GO:0043065 217 0.013
negative regulation of proteolysis GO:0045861 74 0.013
epidermis development GO:0008544 187 0.013
organelle assembly GO:0070925 177 0.013
sulfur compound metabolic process GO:0006790 100 0.013
response to misfolded protein GO:0051788 5 0.013
negative regulation of cellular catabolic process GO:0031330 47 0.013
negative regulation of cell size GO:0045792 3 0.013
regulation of peptidase activity GO:0052547 96 0.013
response to peptide GO:1901652 136 0.013
cellular response to extracellular stimulus GO:0031668 81 0.013
inclusion body assembly GO:0070841 3 0.012
cellular protein complex assembly GO:0043623 116 0.012
negative regulation of protein metabolic process GO:0051248 282 0.012
posttranscriptional gene silencing GO:0016441 10 0.012
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.012
regulation of rho protein signal transduction GO:0035023 71 0.012
negative regulation of cell projection organization GO:0031345 56 0.012
negative regulation of nervous system development GO:0051961 156 0.012
organic acid transport GO:0015849 101 0.012
regulation of neuron projection development GO:0010975 169 0.012
mitotic cell cycle process GO:1903047 159 0.012
receptor mediated endocytosis GO:0006898 51 0.012
oxidation reduction process GO:0055114 342 0.012
positive regulation of nucleotide metabolic process GO:0045981 114 0.012
organic anion transport GO:0015711 137 0.012
rna splicing GO:0008380 54 0.012
stem cell differentiation GO:0048863 268 0.012
nucleoside metabolic process GO:0009116 246 0.012
lipid homeostasis GO:0055088 63 0.012
negative regulation of phosphate metabolic process GO:0045936 184 0.012
regulation of translation GO:0006417 71 0.012
negative regulation of secretion GO:0051048 61 0.012
cell type specific apoptotic process GO:0097285 268 0.012
regulation of protein secretion GO:0050708 82 0.012
establishment of organelle localization GO:0051656 122 0.012
regulation of neurotransmitter levels GO:0001505 87 0.012
positive regulation of ras gtpase activity GO:0032320 65 0.011
regulation of ral gtpase activity GO:0032315 4 0.011
wnt signaling pathway GO:0016055 188 0.011
exocytosis GO:0006887 121 0.011
regulation of cell migration GO:0030334 219 0.011
nitrogen compound transport GO:0071705 271 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
glycosyl compound metabolic process GO:1901657 246 0.011
methylation GO:0032259 134 0.011
steroid metabolic process GO:0008202 119 0.011
response to metal ion GO:0010038 47 0.011
cellular response to inorganic substance GO:0071241 37 0.011
negative regulation of neuron death GO:1901215 98 0.011
dna metabolic process GO:0006259 303 0.011
cell activation involved in immune response GO:0002263 126 0.011
ion transmembrane transport GO:0034220 361 0.011
mrna processing GO:0006397 63 0.011
macromolecule methylation GO:0043414 120 0.011
regulation of transferase activity GO:0051338 263 0.011
rna processing GO:0006396 105 0.011
regulation of cell cycle phase transition GO:1901987 77 0.011
multicellular organismal reproductive behavior GO:0033057 23 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
regulation of ion transmembrane transport GO:0034765 119 0.011
regulation of cysteine type endopeptidase activity GO:2000116 65 0.011
regulation of lymphocyte activation GO:0051249 240 0.011
response to growth factor GO:0070848 198 0.011
negative regulation of growth GO:0045926 99 0.011
negative regulation of cell development GO:0010721 169 0.011
organic acid catabolic process GO:0016054 51 0.011
response to starvation GO:0042594 65 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
Yeast
molting cycle GO:0042303 90 0.011
blastocyst development GO:0001824 80 0.011
aggresome assembly GO:0070842 2 0.011
regulation of leukocyte differentiation GO:1902105 159 0.011
lateral line system development GO:0048925 1 0.010
response to uv GO:0009411 44 0.010
cellular response to organonitrogen compound GO:0071417 145 0.010
cellular response to cadmium ion GO:0071276 3 0.010
regulation of cell activation GO:0050865 289 0.010
attachment of spindle microtubules to kinetochore GO:0008608 4 0.010
cellular lipid metabolic process GO:0044255 323 0.010
tissue homeostasis GO:0001894 115 0.010
regulation of ras gtpase activity GO:0032318 88 0.010
regulation of gtp catabolic process GO:0033124 113 0.010
t cell activation GO:0042110 289 0.010
cellular protein complex disassembly GO:0043624 36 0.010
Fly
negative regulation of secretion by cell GO:1903531 54 0.010
bmp signaling pathway GO:0030509 93 0.010

Usp5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.021
disease of cellular proliferation DOID:14566 0 0.021
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013
organ system cancer DOID:0050686 0 0.012