Mus musculus

0 known processes

Gkn2

gastrokine 2

(Aliases: 1810036H07Rik)

Gkn2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cell proliferation GO:0008285 296 0.151
Mouse
protein maturation GO:0051604 176 0.150
regulation of cellular amine metabolic process GO:0033238 20 0.123
amine metabolic process GO:0009308 45 0.117
epidermis development GO:0008544 187 0.112
skin development GO:0043588 220 0.105
defense response to other organism GO:0098542 197 0.099
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.099
response to lipopolysaccharide GO:0032496 128 0.096
striated muscle tissue development GO:0014706 293 0.095
heterocycle catabolic process GO:0046700 280 0.093
regulation of cellular ketone metabolic process GO:0010565 66 0.090
regulation of cellular amino acid metabolic process GO:0006521 5 0.089
peptidyl amino acid modification GO:0018193 336 0.085
response to organic cyclic compound GO:0014070 198 0.073
regulation of secretion GO:0051046 274 0.072
regulation of defense response GO:0031347 233 0.071
production of molecular mediator of immune response GO:0002440 103 0.070
chemotaxis GO:0006935 247 0.070
cellular amine metabolic process GO:0044106 44 0.069
regulation of cytokine production GO:0001817 266 0.066
cellular amino acid metabolic process GO:0006520 103 0.066
wound healing GO:0042060 157 0.059
macromolecule catabolic process GO:0009057 281 0.059
cellular amide metabolic process GO:0043603 58 0.059
protein processing GO:0016485 163 0.058
regulation of cell activation GO:0050865 289 0.058
organic cyclic compound catabolic process GO:1901361 295 0.057
regulation of cell motility GO:2000145 236 0.056
muscle cell differentiation GO:0042692 261 0.056
positive regulation of protein phosphorylation GO:0001934 242 0.056
inflammatory response GO:0006954 244 0.055
regulation of cell projection organization GO:0031344 206 0.055
positive regulation of protein modification process GO:0031401 299 0.053
small gtpase mediated signal transduction GO:0007264 97 0.052
positive regulation of cellular amine metabolic process GO:0033240 5 0.052
peptide metabolic process GO:0006518 46 0.051
cellular ketone metabolic process GO:0042180 84 0.050
regulation of establishment of protein localization GO:0070201 181 0.049
regulation of cell migration GO:0030334 219 0.047
regulation of transferase activity GO:0051338 263 0.046
response to molecule of bacterial origin GO:0002237 143 0.045
regulation of protein localization GO:0032880 231 0.045
cellular nitrogen compound catabolic process GO:0044270 280 0.043
anion transport GO:0006820 177 0.043
organonitrogen compound catabolic process GO:1901565 264 0.043
cytokine production GO:0001816 319 0.043
nucleoside phosphate catabolic process GO:1901292 222 0.043
sensory organ morphogenesis GO:0090596 242 0.042
regulation of protein transport GO:0051223 163 0.041
skeletal muscle fiber development GO:0048741 58 0.039
myotube differentiation GO:0014902 105 0.038
immune effector process GO:0002252 321 0.038
cellular response to organonitrogen compound GO:0071417 145 0.038
glycosyl compound metabolic process GO:1901657 246 0.038
muscle tissue development GO:0060537 308 0.038
isoprenoid metabolic process GO:0006720 29 0.038
t cell activation GO:0042110 289 0.036
regulation of neuron differentiation GO:0045664 281 0.036
cellular homeostasis GO:0019725 240 0.036
antimicrobial peptide biosynthetic process GO:0002777 2 0.036
positive regulation of apoptotic process GO:0043065 217 0.036
regulation of lymphocyte activation GO:0051249 240 0.035
negative regulation of cytokine production GO:0001818 84 0.035
regulation of epidermis development GO:0045682 33 0.035
cation transport GO:0006812 399 0.035
leukocyte differentiation GO:0002521 342 0.034
sulfur compound metabolic process GO:0006790 100 0.034
regulation of microvillus assembly GO:0032534 3 0.034
cellular response to cytokine stimulus GO:0071345 189 0.034
negative regulation of endothelial cell migration GO:0010596 4 0.034
response to acid chemical GO:0001101 111 0.033
positive regulation of transferase activity GO:0051347 167 0.033
response to organonitrogen compound GO:0010243 246 0.033
nucleotide catabolic process GO:0009166 217 0.033
ribonucleoside catabolic process GO:0042454 206 0.033
humoral immune response GO:0006959 57 0.032
lipid localization GO:0010876 126 0.032
apoptotic signaling pathway GO:0097190 306 0.032
positive regulation of dopamine secretion GO:0033603 2 0.032
skeletal muscle organ development GO:0060538 163 0.031
interspecies interaction between organisms GO:0044419 83 0.031
regulation of epithelial cell proliferation GO:0050678 141 0.031
Mouse
purine containing compound catabolic process GO:0072523 213 0.031
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.031
negative regulation of molecular function GO:0044092 258 0.031
cellular response to lipid GO:0071396 145 0.030
antimicrobial peptide production GO:0002775 2 0.030
regulation of striated muscle cell differentiation GO:0051153 81 0.030
regulation of body fluid levels GO:0050878 162 0.030
negative regulation of protein metabolic process GO:0051248 282 0.030
regulation of kinase activity GO:0043549 249 0.029
positive regulation of cytokine production GO:0001819 174 0.029
positive regulation of cell death GO:0010942 224 0.029
regulation of ion transport GO:0043269 215 0.029
regulation of microvillus organization GO:0032530 3 0.029
carbohydrate derivative catabolic process GO:1901136 231 0.029
camera type eye development GO:0043010 266 0.029
positive regulation of protein transport GO:0051222 93 0.029
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.028
defense response to bacterium GO:0042742 119 0.028
negative regulation of cellular component organization GO:0051129 194 0.028
oxidation reduction process GO:0055114 342 0.028
purine nucleoside triphosphate catabolic process GO:0009146 203 0.028
ribonucleotide catabolic process GO:0009261 208 0.028
hematopoietic progenitor cell differentiation GO:0002244 143 0.027
ribonucleoside metabolic process GO:0009119 245 0.027
regulation of neuron projection development GO:0010975 169 0.027
adaptive immune response GO:0002250 155 0.027
nucleoside triphosphate metabolic process GO:0009141 230 0.026
inorganic cation transmembrane transport GO:0098662 207 0.026
nucleotide metabolic process GO:0009117 332 0.026
positive regulation of kinase activity GO:0033674 155 0.026
negative regulation of phosphorylation GO:0042326 166 0.026
embryonic placenta development GO:0001892 98 0.026
regulation of secretion by cell GO:1903530 249 0.026
regulation of interleukin 6 production GO:0032675 55 0.026
regulation of protein kinase activity GO:0045859 232 0.026
regulation of fat cell differentiation GO:0045598 81 0.025
g protein coupled receptor signaling pathway GO:0007186 243 0.025
positive regulation of homeostatic process GO:0032846 64 0.025
regulation of lymphocyte differentiation GO:0045619 107 0.025
negative regulation of cellular protein metabolic process GO:0032269 247 0.025
positive regulation of eosinophil migration GO:2000418 2 0.024
maintenance of location GO:0051235 89 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.024
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.024
cellular macromolecule catabolic process GO:0044265 206 0.024
nucleoside catabolic process GO:0009164 206 0.024
purine nucleoside catabolic process GO:0006152 205 0.024
action potential GO:0001508 78 0.024
myotube cell development GO:0014904 60 0.024
regulation of system process GO:0044057 200 0.023
aromatic compound catabolic process GO:0019439 286 0.023
regulation of response to wounding GO:1903034 189 0.023
angiogenesis GO:0001525 201 0.023
regulation of inflammatory response GO:0050727 147 0.023
purine nucleotide metabolic process GO:0006163 302 0.023
peptidyl tyrosine modification GO:0018212 145 0.023
purine ribonucleotide catabolic process GO:0009154 208 0.023
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.022
transmission of nerve impulse GO:0019226 76 0.022
protein secretion GO:0009306 111 0.022
regulation of protein maturation GO:1903317 96 0.022
positive regulation of cell migration GO:0030335 109 0.022
blood vessel morphogenesis GO:0048514 285 0.022
myoblast differentiation GO:0045445 52 0.022
cellular chemical homeostasis GO:0055082 215 0.022
multicellular organismal homeostasis GO:0048871 164 0.022
regulation of protein secretion GO:0050708 82 0.022
hair cycle GO:0042633 90 0.021
negative regulation of cell activation GO:0050866 111 0.021
regulation of epidermal cell differentiation GO:0045604 21 0.021
cellular ion homeostasis GO:0006873 165 0.021
purine ribonucleoside catabolic process GO:0046130 205 0.021
molting cycle GO:0042303 90 0.021
negative regulation of immune system process GO:0002683 209 0.021
defense response to virus GO:0051607 68 0.020
inorganic ion transmembrane transport GO:0098660 234 0.020
positive regulation of programmed cell death GO:0043068 218 0.020
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.020
ribonucleoside triphosphate catabolic process GO:0009203 199 0.020
digestive tract development GO:0048565 190 0.020
nucleoside phosphate metabolic process GO:0006753 338 0.020
positive regulation of protein kinase activity GO:0045860 144 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
cell differentiation involved in embryonic placenta development GO:0060706 26 0.020
negative regulation of protein modification process GO:0031400 163 0.020
keratinocyte differentiation GO:0030216 48 0.020
regulation of defense response to bacterium GO:1900424 3 0.020
regulation of cell cycle GO:0051726 281 0.020
positive regulation of immune effector process GO:0002699 107 0.020
cofactor metabolic process GO:0051186 80 0.020
regulation of hydrolase activity GO:0051336 246 0.019
epithelial cell proliferation GO:0050673 174 0.019
Mouse
regulation of vasculature development GO:1901342 88 0.019
peptidyl tyrosine phosphorylation GO:0018108 143 0.019
compound eye development GO:0048749 1 0.019
posttranscriptional regulation of gene expression GO:0010608 155 0.019
multicellular organismal signaling GO:0035637 91 0.019
nucleoside metabolic process GO:0009116 246 0.019
positive regulation of cell motility GO:2000147 116 0.019
regulation of myotube differentiation GO:0010830 62 0.019
regulation of leukocyte differentiation GO:1902105 159 0.019
blastocyst development GO:0001824 80 0.019
leukocyte proliferation GO:0070661 172 0.019
regulation of t cell activation GO:0050863 170 0.019
homeostasis of number of cells GO:0048872 210 0.018
hair follicle development GO:0001942 85 0.018
skeletal system development GO:0001501 356 0.018
regulation of neuron apoptotic process GO:0043523 122 0.018
nitrogen compound transport GO:0071705 271 0.018
binding of sperm to zona pellucida GO:0007339 34 0.018
multi multicellular organism process GO:0044706 109 0.018
regulation of organelle organization GO:0033043 289 0.018
ribonucleoside triphosphate metabolic process GO:0009199 220 0.018
negative regulation of growth GO:0045926 99 0.018
nucleoside triphosphate catabolic process GO:0009143 205 0.018
morphogenesis of a branching epithelium GO:0061138 193 0.018
jak stat cascade GO:0007259 42 0.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.018
glycerolipid metabolic process GO:0046486 122 0.018
intracellular protein transport GO:0006886 204 0.017
zymogen activation GO:0031638 41 0.017
bone development GO:0060348 120 0.017
regulation of muscle tissue development GO:1901861 97 0.017
ear morphogenesis GO:0042471 118 0.017
regulation of skeletal muscle fiber development GO:0048742 36 0.017
regulation of multi organism process GO:0043900 111 0.017
norepinephrine transport GO:0015874 2 0.017
cellular response to organic cyclic compound GO:0071407 87 0.017
neural tube development GO:0021915 160 0.017
cytokine mediated signaling pathway GO:0019221 115 0.017
regulation of membrane potential GO:0042391 192 0.017
morphogenesis of a branching structure GO:0001763 203 0.017
positive regulation of thymocyte migration GO:2000412 2 0.017
negative regulation of phosphorus metabolic process GO:0010563 184 0.017
blood coagulation GO:0007596 76 0.017
mitotic cell cycle GO:0000278 195 0.016
regulation of antimicrobial humoral response GO:0002759 3 0.016
peptidyl serine modification GO:0018209 83 0.016
protein activation cascade GO:0072376 19 0.016
regulation of interleukin 1 alpha production GO:0032650 4 0.016
negative regulation of lipid metabolic process GO:0045833 30 0.016
negative regulation of t cell activation GO:0050868 65 0.016
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.016
positive regulation of cell activation GO:0050867 158 0.016
positive regulation of secretion GO:0051047 130 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.016
nucleobase containing small molecule metabolic process GO:0055086 352 0.016
placenta development GO:0001890 140 0.016
regulation of production of molecular mediator of immune response GO:0002700 65 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
positive regulation of antimicrobial humoral response GO:0002760 2 0.016
antibacterial peptide biosynthetic process GO:0002780 2 0.016
cytoplasmic transport GO:0016482 234 0.016
cellular modified amino acid metabolic process GO:0006575 63 0.016
anatomical structure homeostasis GO:0060249 145 0.016
negative regulation of response to wounding GO:1903035 77 0.016
negative regulation of multi organism process GO:0043901 68 0.016
stem cell proliferation GO:0072089 117 0.015
epithelial tube morphogenesis GO:0060562 303 0.015
negative regulation of myoblast differentiation GO:0045662 18 0.015
glucose homeostasis GO:0042593 128 0.015
skeletal system morphogenesis GO:0048705 203 0.015
organonitrogen compound biosynthetic process GO:1901566 192 0.015
leukocyte mediated immunity GO:0002443 174 0.015
regulation of neurotransmitter levels GO:0001505 87 0.015
glycosyl compound catabolic process GO:1901658 206 0.015
t cell differentiation GO:0030217 174 0.015
protein targeting GO:0006605 143 0.015
sensory perception GO:0007600 245 0.015
regulation of antimicrobial peptide biosynthetic process GO:0002805 1 0.015
nerve development GO:0021675 67 0.015
blood circulation GO:0008015 195 0.015
embryonic organ morphogenesis GO:0048562 276 0.015
negative regulation of defense response GO:0031348 77 0.015
b cell activation GO:0042113 161 0.015
regulation of mapk cascade GO:0043408 248 0.015
positive regulation of response to wounding GO:1903036 66 0.015
response to peptide hormone GO:0043434 127 0.015
regulation of cell growth GO:0001558 91 0.015
ameboidal type cell migration GO:0001667 128 0.015
organic anion transport GO:0015711 137 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.014
cell recognition GO:0008037 83 0.014
neuron apoptotic process GO:0051402 142 0.014
protein oligomerization GO:0051259 67 0.014
positive regulation of cellular catabolic process GO:0031331 148 0.014
positive regulation of nucleotide catabolic process GO:0030813 88 0.014
alcohol metabolic process GO:0006066 116 0.014
sensory perception of mechanical stimulus GO:0050954 107 0.014
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.014
nuclear transport GO:0051169 139 0.014
cell maturation GO:0048469 127 0.014
cellular response to peptide GO:1901653 92 0.014
regulation of neuron death GO:1901214 134 0.014
leukocyte migration GO:0050900 124 0.014
regulation of angiogenesis GO:0045765 81 0.014
lymphocyte differentiation GO:0030098 242 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
positive regulation of cell projection organization GO:0031346 95 0.014
regulation of anatomical structure size GO:0090066 178 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
diterpenoid metabolic process GO:0016101 24 0.014
neuronal action potential GO:0019228 54 0.014
response to amino acid GO:0043200 37 0.013
regulation of keratinocyte differentiation GO:0045616 11 0.013
regulation of nucleotide metabolic process GO:0006140 169 0.013
spermatogenesis GO:0007283 284 0.013
regulation of myoblast differentiation GO:0045661 29 0.013
photoreceptor cell development GO:0042461 40 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
muscle fiber development GO:0048747 76 0.013
metal ion homeostasis GO:0055065 189 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.013
striated muscle cell development GO:0055002 125 0.013
peptidyl serine phosphorylation GO:0018105 74 0.013
fertilization GO:0009566 127 0.013
cartilage development GO:0051216 140 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.013
gland development GO:0048732 330 0.013
regulation of organ morphogenesis GO:2000027 144 0.013
negative regulation of cell development GO:0010721 169 0.013
cell chemotaxis GO:0060326 81 0.013
organophosphate catabolic process GO:0046434 232 0.013
ion transmembrane transport GO:0034220 361 0.013
positive regulation of angiogenesis GO:0045766 46 0.013
lymphocyte mediated immunity GO:0002449 139 0.013
gtp catabolic process GO:0006184 143 0.013
lymphocyte activation involved in immune response GO:0002285 93 0.013
chondroitin sulfate metabolic process GO:0030204 17 0.013
organophosphate biosynthetic process GO:0090407 122 0.013
muscle contraction GO:0006936 101 0.013
regulation of ras protein signal transduction GO:0046578 114 0.013
nephron development GO:0072006 109 0.012
regulation of thymocyte migration GO:2000410 2 0.012
tissue remodeling GO:0048771 102 0.012
regulation of antimicrobial peptide production GO:0002784 1 0.012
regulation of feeding behavior GO:0060259 3 0.012
regulation of protein processing GO:0070613 96 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
guanosine containing compound catabolic process GO:1901069 144 0.012
thymocyte migration GO:0072679 2 0.012
developmental maturation GO:0021700 193 0.012
positive regulation of antimicrobial peptide production GO:0002225 1 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.012
regulation of b cell activation GO:0050864 81 0.012
negative regulation of muscle cell differentiation GO:0051148 33 0.012
cellularization GO:0007349 1 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
divalent inorganic cation transport GO:0072511 178 0.012
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 1 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
negative regulation of cell cycle GO:0045786 123 0.012
paramesonephric duct development GO:0061205 3 0.012
muscle cell development GO:0055001 133 0.012
cellular response to amino acid stimulus GO:0071230 29 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
acute inflammatory response GO:0002526 41 0.012
regulation of t cell differentiation GO:0045580 83 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
purine ribonucleotide metabolic process GO:0009150 290 0.012
purine nucleoside metabolic process GO:0042278 241 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
sequestering of calcium ion GO:0051208 18 0.012
ear development GO:0043583 200 0.012
protein modification by small protein conjugation GO:0032446 187 0.012
cdc42 protein signal transduction GO:0032488 0 0.012
ras protein signal transduction GO:0007265 77 0.012
feeding behavior GO:0007631 62 0.012
calcium ion transport GO:0006816 159 0.011
mapk cascade GO:0000165 281 0.011
somitogenesis GO:0001756 69 0.011
negative regulation of cell motility GO:2000146 61 0.011
cellular response to acid chemical GO:0071229 68 0.011
trophoblast giant cell differentiation GO:0060707 15 0.011
positive regulation of interleukin 8 production GO:0032757 2 0.011
organelle fission GO:0048285 170 0.011
gtp metabolic process GO:0046039 144 0.011
regulation of reproductive process GO:2000241 66 0.011
positive regulation of catecholamine secretion GO:0033605 2 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
organ growth GO:0035265 117 0.011
dna metabolic process GO:0006259 303 0.011
ribose phosphate metabolic process GO:0019693 291 0.011
cation homeostasis GO:0055080 212 0.011
adult behavior GO:0030534 135 0.011
interleukin 8 production GO:0032637 4 0.011
cellular protein complex assembly GO:0043623 116 0.011
limb development GO:0060173 166 0.011
antibacterial peptide production GO:0002778 2 0.011
positive regulation of interleukin 1 alpha production GO:0032730 4 0.011
regulation of antibacterial peptide production GO:0002786 1 0.011
negative regulation of hydrolase activity GO:0051346 71 0.011
regulation of phospholipase a2 activity GO:0032429 3 0.011
cellular response to abiotic stimulus GO:0071214 56 0.011
divalent metal ion transport GO:0070838 172 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
response to insulin GO:0032868 100 0.011
negative regulation of phosphate metabolic process GO:0045936 184 0.011
bone morphogenesis GO:0060349 78 0.011
nephron epithelium development GO:0072009 92 0.011
respiratory system development GO:0060541 190 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
cellular response to insulin stimulus GO:0032869 78 0.011
rho protein signal transduction GO:0007266 32 0.011
cellular response to extracellular stimulus GO:0031668 81 0.011
negative regulation of hormone metabolic process GO:0032351 4 0.011
lipid storage GO:0019915 36 0.011
positive regulation of defense response to bacterium GO:1900426 1 0.010
renal system development GO:0072001 225 0.010
regulation of mitotic cell cycle GO:0007346 126 0.010
auditory receptor cell differentiation GO:0042491 37 0.010
negative regulation of lymphocyte differentiation GO:0045620 32 0.010
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.010
regionalization GO:0003002 337 0.010
cation transmembrane transport GO:0098655 266 0.010
positive regulation of epithelial cell proliferation GO:0050679 68 0.010
male gamete generation GO:0048232 285 0.010
calcium ion homeostasis GO:0055074 127 0.010
negative regulation of protein processing GO:0010955 79 0.010
ensheathment of neurons GO:0007272 76 0.010
negative regulation of inflammatory response GO:0050728 61 0.010
positive regulation of ion transport GO:0043270 65 0.010
positive regulation of cell adhesion GO:0045785 80 0.010
endocytosis GO:0006897 168 0.010
defense response to gram negative bacterium GO:0050829 28 0.010
cardiac muscle tissue morphogenesis GO:0055008 44 0.010
membrane organization GO:0061024 245 0.010
cell type specific apoptotic process GO:0097285 268 0.010
carbohydrate homeostasis GO:0033500 128 0.010
positive regulation of t cell activation GO:0050870 101 0.010
protein catabolic process GO:0030163 221 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.010
response to nutrient levels GO:0031667 109 0.010
negative regulation of neuron differentiation GO:0045665 101 0.010

Gkn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.041
inherited metabolic disorder DOID:655 0 0.012