Mus musculus

0 known processes

Ppme1

protein phosphatase methylesterase 1

(Aliases: 2700017M01Rik,Pme1,1110069N17Rik,PME-1)

Ppme1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ras protein signal transduction GO:0007265 77 0.094
protein modification by small protein conjugation GO:0032446 187 0.089
small gtpase mediated signal transduction GO:0007264 97 0.073
nucleoside phosphate metabolic process GO:0006753 338 0.068
nucleobase containing small molecule metabolic process GO:0055086 352 0.068
oocyte axis specification GO:0007309 2 0.067
cellular amino acid metabolic process GO:0006520 103 0.064
ribose phosphate metabolic process GO:0019693 291 0.059
cellular amine metabolic process GO:0044106 44 0.057
microtubule based process GO:0007017 236 0.056
aromatic compound catabolic process GO:0019439 286 0.055
positive regulation of cellular amine metabolic process GO:0033240 5 0.055
organic cyclic compound catabolic process GO:1901361 295 0.055
synaptic transmission GO:0007268 329 0.053
nucleotide metabolic process GO:0009117 332 0.053
mitotic cell cycle GO:0000278 195 0.052
cellular nitrogen compound catabolic process GO:0044270 280 0.050
retrograde transport endosome to golgi GO:0042147 2 0.050
mapk cascade GO:0000165 281 0.050
regulation of cellular amino acid metabolic process GO:0006521 5 0.049
heterocycle catabolic process GO:0046700 280 0.049
purine containing compound metabolic process GO:0072521 311 0.049
nucleoside metabolic process GO:0009116 246 0.048
macromolecule catabolic process GO:0009057 281 0.048
peptidyl amino acid modification GO:0018193 336 0.048
protein catabolic process GO:0030163 221 0.046
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.046
amine metabolic process GO:0009308 45 0.046
nucleoside phosphate catabolic process GO:1901292 222 0.044
negative regulation of protein metabolic process GO:0051248 282 0.044
cellular ketone metabolic process GO:0042180 84 0.043
regulation of cellular ketone metabolic process GO:0010565 66 0.042
purine ribonucleotide metabolic process GO:0009150 290 0.042
purine nucleoside triphosphate catabolic process GO:0009146 203 0.041
oocyte construction GO:0007308 2 0.041
protein modification by small protein conjugation or removal GO:0070647 207 0.041
regulation of mapk cascade GO:0043408 248 0.041
response to organonitrogen compound GO:0010243 246 0.040
negative regulation of cellular protein metabolic process GO:0032269 247 0.040
nucleotide catabolic process GO:0009166 217 0.039
purine ribonucleoside metabolic process GO:0046128 241 0.039
ribonucleoside metabolic process GO:0009119 245 0.039
positive regulation of protein modification process GO:0031401 299 0.039
cation transport GO:0006812 399 0.039
axonogenesis GO:0007409 274 0.039
guanosine containing compound catabolic process GO:1901069 144 0.039
positive regulation of cellular catabolic process GO:0031331 148 0.038
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.038
cytoplasmic transport GO:0016482 234 0.038
cellular lipid metabolic process GO:0044255 323 0.037
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.037
protein ubiquitination GO:0016567 171 0.037
regulation of secretion GO:0051046 274 0.037
regulation of transferase activity GO:0051338 263 0.037
modification dependent protein catabolic process GO:0019941 133 0.037
organophosphate catabolic process GO:0046434 232 0.036
purine nucleoside metabolic process GO:0042278 241 0.036
dephosphorylation GO:0016311 129 0.036
ribonucleotide metabolic process GO:0009259 291 0.035
purine nucleotide metabolic process GO:0006163 302 0.035
apoptotic signaling pathway GO:0097190 306 0.034
monocarboxylic acid metabolic process GO:0032787 191 0.034
microtubule cytoskeleton organization GO:0000226 157 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.034
male gamete generation GO:0048232 285 0.034
intracellular protein transport GO:0006886 204 0.033
glycosyl compound catabolic process GO:1901658 206 0.033
germ cell development GO:0007281 185 0.033
carbohydrate derivative catabolic process GO:1901136 231 0.033
transmembrane transport GO:0055085 412 0.033
cellular homeostasis GO:0019725 240 0.032
actin cytoskeleton organization GO:0030036 220 0.032
modification dependent macromolecule catabolic process GO:0043632 133 0.032
negative regulation of molecular function GO:0044092 258 0.032
nitrogen compound transport GO:0071705 271 0.031
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.031
pole plasm assembly GO:0007315 2 0.031
endocytosis GO:0006897 168 0.031
ribonucleoside triphosphate catabolic process GO:0009203 199 0.031
olfactory learning GO:0008355 2 0.030
nucleoside triphosphate catabolic process GO:0009143 205 0.029
regulation of protein localization GO:0032880 231 0.029
regulation of secretion by cell GO:1903530 249 0.029
cellular component assembly involved in morphogenesis GO:0010927 139 0.029
regulation of purine nucleotide metabolic process GO:1900542 169 0.029
negative regulation of intracellular signal transduction GO:1902532 167 0.029
nucleoside triphosphate metabolic process GO:0009141 230 0.029
protein localization to organelle GO:0033365 185 0.028
carbohydrate metabolic process GO:0005975 230 0.028
positive regulation of protein phosphorylation GO:0001934 242 0.028
regulation of kinase activity GO:0043549 249 0.028
negative regulation of phosphorylation GO:0042326 166 0.028
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.027
regulation of protein kinase activity GO:0045859 232 0.027
regulation of cell cycle GO:0051726 281 0.027
spermatogenesis GO:0007283 284 0.027
gtp metabolic process GO:0046039 144 0.027
negative regulation of protein modification process GO:0031400 163 0.027
ribonucleoside catabolic process GO:0042454 206 0.026
purine nucleoside triphosphate metabolic process GO:0009144 226 0.026
guanosine containing compound metabolic process GO:1901068 144 0.026
regulation of cellular catabolic process GO:0031329 242 0.026
regulation of vesicle mediated transport GO:0060627 139 0.026
ribonucleoside triphosphate metabolic process GO:0009199 220 0.026
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.026
dna metabolic process GO:0006259 303 0.026
organelle assembly GO:0070925 177 0.026
purine containing compound catabolic process GO:0072523 213 0.026
regulation of hydrolase activity GO:0051336 246 0.026
regulation of organelle organization GO:0033043 289 0.025
cellular protein catabolic process GO:0044257 155 0.025
response to inorganic substance GO:0010035 96 0.025
purine ribonucleotide catabolic process GO:0009154 208 0.025
positive regulation of cell death GO:0010942 224 0.025
purine nucleoside catabolic process GO:0006152 205 0.024
ribonucleotide catabolic process GO:0009261 208 0.024
intracellular mrna localization GO:0008298 4 0.024
anion transport GO:0006820 177 0.024
regulation of neuron differentiation GO:0045664 281 0.024
cellular protein complex assembly GO:0043623 116 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.024
inclusion body assembly GO:0070841 3 0.024
purine nucleotide catabolic process GO:0006195 211 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.024
cellular chemical homeostasis GO:0055082 215 0.024
nuclear division GO:0000280 158 0.023
organonitrogen compound catabolic process GO:1901565 264 0.023
exocytosis GO:0006887 121 0.023
ion transmembrane transport GO:0034220 361 0.023
sensory perception GO:0007600 245 0.023
rho protein signal transduction GO:0007266 32 0.023
regulation of nucleoside metabolic process GO:0009118 130 0.023
purine ribonucleoside catabolic process GO:0046130 205 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.022
negative regulation of phosphorus metabolic process GO:0010563 184 0.022
regulation of hormone levels GO:0010817 211 0.022
regulation of cellular response to stress GO:0080135 159 0.022
cellular macromolecule catabolic process GO:0044265 206 0.022
nucleoside catabolic process GO:0009164 206 0.022
organic hydroxy compound metabolic process GO:1901615 203 0.022
negative regulation of phosphate metabolic process GO:0045936 184 0.022
regulation of nucleotide metabolic process GO:0006140 169 0.022
organelle localization GO:0051640 179 0.022
posttranscriptional regulation of gene expression GO:0010608 155 0.022
developmental maturation GO:0021700 193 0.022
positive regulation of nucleotide metabolic process GO:0045981 114 0.021
inorganic ion transmembrane transport GO:0098660 234 0.021
maintenance of location GO:0051235 89 0.021
regulation of exocytosis GO:0017157 61 0.021
regulation of ras protein signal transduction GO:0046578 114 0.020
glycosyl compound metabolic process GO:1901657 246 0.020
negative regulation of protein phosphorylation GO:0001933 126 0.020
positive regulation of transferase activity GO:0051347 167 0.020
organelle fission GO:0048285 170 0.020
locomotory behavior GO:0007626 195 0.020
regulation of cell activation GO:0050865 289 0.020
regulation of intracellular transport GO:0032386 159 0.020
compound eye development GO:0048749 1 0.020
membrane organization GO:0061024 245 0.020
cell adhesion GO:0007155 329 0.019
establishment of vesicle localization GO:0051650 81 0.019
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.019
cell maturation GO:0048469 127 0.019
cell growth GO:0016049 130 0.019
response to organic cyclic compound GO:0014070 198 0.018
gtp catabolic process GO:0006184 143 0.018
asymmetric stem cell division GO:0098722 3 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
glucose homeostasis GO:0042593 128 0.018
fat cell differentiation GO:0045444 160 0.018
striated muscle myosin thick filament assembly GO:0071688 1 0.018
positive regulation of hydrolase activity GO:0051345 148 0.018
mitochondrion organization GO:0007005 134 0.018
positive regulation of nucleoside metabolic process GO:0045979 91 0.018
organic anion transport GO:0015711 137 0.018
mitotic cell cycle process GO:1903047 159 0.018
organonitrogen compound biosynthetic process GO:1901566 192 0.018
ubiquitin dependent protein catabolic process GO:0006511 129 0.017
oocyte anterior posterior axis specification GO:0007314 2 0.017
maternal determination of anterior posterior axis embryo GO:0008358 2 0.017
oxidation reduction process GO:0055114 342 0.017
regulation of ion transport GO:0043269 215 0.017
homeostasis of number of cells GO:0048872 210 0.017
response to oxidative stress GO:0006979 123 0.017
protein oligomerization GO:0051259 67 0.017
regulation of gtp catabolic process GO:0033124 113 0.017
regulation of cell projection organization GO:0031344 206 0.017
establishment or maintenance of cell polarity GO:0007163 86 0.017
regulation of nucleotide catabolic process GO:0030811 122 0.017
positive regulation of mapk cascade GO:0043410 170 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
cognition GO:0050890 149 0.017
jnk cascade GO:0007254 72 0.017
myosin filament organization GO:0031033 3 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
positive regulation of gtpase activity GO:0043547 85 0.016
neurotransmitter transport GO:0006836 76 0.016
positive regulation of programmed cell death GO:0043068 218 0.016
response to peptide GO:1901652 136 0.016
myosin filament assembly GO:0031034 2 0.016
cation homeostasis GO:0055080 212 0.016
positive regulation of kinase activity GO:0033674 155 0.016
organic acid transport GO:0015849 101 0.016
striated muscle tissue development GO:0014706 293 0.016
cellular response to organonitrogen compound GO:0071417 145 0.016
regulation of cellular component biogenesis GO:0044087 181 0.016
positive regulation of cell development GO:0010720 237 0.016
establishment of organelle localization GO:0051656 122 0.016
regionalization GO:0003002 337 0.016
regulation of proteolysis GO:0030162 164 0.016
lipid transport GO:0006869 98 0.016
regulation of establishment of protein localization GO:0070201 181 0.016
spermatid differentiation GO:0048515 115 0.016
reactive oxygen species metabolic process GO:0072593 84 0.016
learning or memory GO:0007611 148 0.016
response to radiation GO:0009314 165 0.016
skin development GO:0043588 220 0.016
immune effector process GO:0002252 321 0.016
histone modification GO:0016570 159 0.016
muscle tissue development GO:0060537 308 0.015
rab protein signal transduction GO:0032482 1 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.015
hormone secretion GO:0046879 128 0.015
regulation of homeostatic process GO:0032844 182 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
sensory system development GO:0048880 3 0.015
cation transmembrane transport GO:0098655 266 0.015
regulation of cell migration GO:0030334 219 0.015
vesicle localization GO:0051648 86 0.015
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.015
blood circulation GO:0008015 195 0.015
adult behavior GO:0030534 135 0.015
response to light stimulus GO:0009416 135 0.015
regulation of neuron projection development GO:0010975 169 0.015
mrna metabolic process GO:0016071 84 0.015
regulation of purine nucleotide catabolic process GO:0033121 122 0.015
muscle system process GO:0003012 141 0.015
regulation of apoptotic signaling pathway GO:2001233 197 0.015
regulation of mitotic cell cycle GO:0007346 126 0.015
peptide hormone secretion GO:0030072 109 0.015
positive regulation of organelle organization GO:0010638 128 0.014
metal ion homeostasis GO:0055065 189 0.014
regulation of cell cycle process GO:0010564 160 0.014
cellular response to cytokine stimulus GO:0071345 189 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
positive regulation of nucleotide catabolic process GO:0030813 88 0.014
response to insulin GO:0032868 100 0.014
g protein coupled receptor signaling pathway GO:0007186 243 0.014
cellular response to hormone stimulus GO:0032870 150 0.014
endomembrane system organization GO:0010256 147 0.014
regulation of multi organism process GO:0043900 111 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
regulation of ras gtpase activity GO:0032318 88 0.014
negative regulation of cell development GO:0010721 169 0.014
lipid localization GO:0010876 126 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
lipid biosynthetic process GO:0008610 179 0.014
carbohydrate homeostasis GO:0033500 128 0.014
cell division GO:0051301 120 0.014
regulation of neurotransmitter levels GO:0001505 87 0.014
glycerolipid metabolic process GO:0046486 122 0.014
positive regulation of secretion GO:0051047 130 0.014
dna repair GO:0006281 107 0.014
muscle cell differentiation GO:0042692 261 0.014
negative regulation of nervous system development GO:0051961 156 0.014
embryonic organ morphogenesis GO:0048562 276 0.014
multicellular organismal homeostasis GO:0048871 164 0.014
small molecule catabolic process GO:0044282 71 0.013
chemotaxis GO:0006935 247 0.013
urogenital system development GO:0001655 261 0.013
regulation of cell motility GO:2000145 236 0.013
localization within membrane GO:0051668 4 0.013
insulin secretion GO:0030073 89 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.013
digestive system development GO:0055123 200 0.013
negative regulation of synapse assembly GO:0051964 3 0.013
habituation GO:0046959 3 0.013
amide transport GO:0042886 138 0.013
forebrain development GO:0030900 302 0.013
positive regulation of nervous system development GO:0051962 221 0.013
protein targeting GO:0006605 143 0.013
response to peptide hormone GO:0043434 127 0.013
response to nutrient levels GO:0031667 109 0.013
circulatory system process GO:0003013 197 0.013
fertilization GO:0009566 127 0.013
inorganic cation transmembrane transport GO:0098662 207 0.013
response to lipopolysaccharide GO:0032496 128 0.013
lymphocyte proliferation GO:0046651 164 0.013
blood vessel morphogenesis GO:0048514 285 0.013
mitotic nuclear division GO:0007067 48 0.013
negative regulation of cell cycle GO:0045786 123 0.013
response to decreased oxygen levels GO:0036293 59 0.013
positive regulation of protein kinase activity GO:0045860 144 0.013
cellularization GO:0007349 1 0.013
response to oxygen levels GO:0070482 62 0.013
second messenger mediated signaling GO:0019932 73 0.013
peptide transport GO:0015833 133 0.013
cell type specific apoptotic process GO:0097285 268 0.013
neuron death GO:0070997 154 0.013
positive regulation of growth GO:0045927 104 0.012
negative regulation of growth GO:0045926 99 0.012
regulation of cytoplasmic transport GO:1903649 112 0.012
leukocyte differentiation GO:0002521 342 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.012
negative regulation of transferase activity GO:0051348 85 0.012
wound healing GO:0042060 157 0.012
renal system development GO:0072001 225 0.012
lateral line system development GO:0048925 1 0.012
circadian rhythm GO:0007623 114 0.012
t cell activation GO:0042110 289 0.012
smoothened signaling pathway GO:0007224 105 0.012
negative regulation of kinase activity GO:0033673 81 0.012
female gamete generation GO:0007292 74 0.012
regulation of system process GO:0044057 200 0.012
regulation of protein transport GO:0051223 163 0.012
regulation of synaptic plasticity GO:0048167 87 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
fatty acid metabolic process GO:0006631 121 0.012
cytokine production GO:0001816 319 0.012
cellular response to external stimulus GO:0071496 88 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
wnt signaling pathway GO:0016055 188 0.012
sequestering of calcium ion GO:0051208 18 0.012
placenta development GO:0001890 140 0.012
respiratory system development GO:0060541 190 0.012
misfolded protein transport GO:0070843 1 0.012
inflammatory response GO:0006954 244 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.012
regulation of anatomical structure size GO:0090066 178 0.012
neuron neuron synaptic transmission GO:0007270 69 0.012
carboxylic acid transport GO:0046942 100 0.012
response to extracellular stimulus GO:0009991 127 0.012
regulation of body fluid levels GO:0050878 162 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.012
spermatid development GO:0007286 108 0.012
alcohol metabolic process GO:0006066 116 0.012
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.012
extracellular matrix organization GO:0030198 147 0.012
asymmetric neuroblast division GO:0055059 1 0.012
erk1 and erk2 cascade GO:0070371 77 0.012
regulation of cytokine production GO:0001817 266 0.011
synaptic vesicle localization GO:0097479 59 0.011
heart morphogenesis GO:0003007 178 0.011
rhythmic process GO:0048511 174 0.011
camera type eye development GO:0043010 266 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
cellular ion homeostasis GO:0006873 165 0.011
regulation of stress activated mapk cascade GO:0032872 69 0.011
myeloid cell homeostasis GO:0002262 114 0.011
b cell activation GO:0042113 161 0.011
translation GO:0006412 93 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.011
lymphocyte differentiation GO:0030098 242 0.011
engulfment of apoptotic cell GO:0043652 3 0.011
cilium morphogenesis GO:0060271 102 0.011
meiotic cell cycle GO:0051321 122 0.011
glycerophospholipid metabolic process GO:0006650 71 0.011
neural precursor cell proliferation GO:0061351 121 0.011
zygotic determination of anterior posterior axis embryo GO:0007354 3 0.011
regulation of translation GO:0006417 71 0.011
epithelial tube morphogenesis GO:0060562 303 0.011
pyruvate metabolic process GO:0006090 28 0.011
ossification GO:0001503 216 0.011
regulation of endocytosis GO:0030100 69 0.011
protein maturation GO:0051604 176 0.011
cellular metal ion homeostasis GO:0006875 151 0.011
regulation of peptide transport GO:0090087 91 0.011
microtubule nucleation GO:0007020 2 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
regulation of protein catabolic process GO:0042176 108 0.011
chromatin organization GO:0006325 206 0.011
positive regulation of dna templated transcription elongation GO:0032786 2 0.011
developmental growth involved in morphogenesis GO:0060560 138 0.011
regulation of binding GO:0051098 111 0.011
mitochondrion distribution GO:0048311 4 0.011
inter male aggressive behavior GO:0002121 3 0.011
protein localization to endosome GO:0036010 2 0.011
transmission of nerve impulse GO:0019226 76 0.011
sensory organ morphogenesis GO:0090596 242 0.011
epithelial cell development GO:0002064 159 0.011
regulation of wnt signaling pathway GO:0030111 123 0.011
vesicle organization GO:0016050 60 0.011
small molecule biosynthetic process GO:0044283 132 0.011
calcium ion transport GO:0006816 159 0.011
anatomical structure homeostasis GO:0060249 145 0.011
regulation of neuron death GO:1901214 134 0.011
microtubule based transport GO:0010970 50 0.011
response to growth factor GO:0070848 198 0.011
regulation of map kinase activity GO:0043405 120 0.011
neuron apoptotic process GO:0051402 142 0.010
response to acid chemical GO:0001101 111 0.010
multicellular organism growth GO:0035264 161 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.010
regulation of metal ion transport GO:0010959 106 0.010
stress activated protein kinase signaling cascade GO:0031098 81 0.010
oogenesis GO:0048477 56 0.010
neurotransmitter secretion GO:0007269 62 0.010
regulation of protein serine threonine kinase activity GO:0071900 157 0.010
divalent metal ion transport GO:0070838 172 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
cellular response to peptide hormone stimulus GO:0071375 92 0.010
regulation of transmembrane transport GO:0034762 128 0.010
protein localization to nucleus GO:0034504 121 0.010
macromolecular complex disassembly GO:0032984 43 0.010
monosaccharide transport GO:0015749 58 0.010
rna interference GO:0016246 2 0.010
organophosphate biosynthetic process GO:0090407 122 0.010
ear development GO:0043583 200 0.010
regulation of jnk cascade GO:0046328 62 0.010
cofactor metabolic process GO:0051186 80 0.010
peptide secretion GO:0002790 114 0.010
protein processing GO:0016485 163 0.010
stress activated mapk cascade GO:0051403 80 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
rhodopsin mediated signaling pathway GO:0016056 4 0.010

Ppme1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.037
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.022
hematopoietic system disease DOID:74 0 0.014
disease of cellular proliferation DOID:14566 0 0.012
musculoskeletal system disease DOID:17 0 0.012
disease of metabolism DOID:0014667 0 0.011
neuropathy DOID:870 0 0.011
central nervous system disease DOID:331 0 0.011
cancer DOID:162 0 0.010
organ system cancer DOID:0050686 0 0.010