Mus musculus

227 known processes

Egf

epidermal growth factor

(Aliases: AI790464)

Egf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.385
Human
ion transmembrane transport GO:0034220 361 0.239
Human
amino acid transmembrane transport GO:0003333 37 0.213
cation transmembrane transport GO:0098655 266 0.147
amino acid transport GO:0006865 61 0.143
nitrogen compound transport GO:0071705 271 0.102
Mouse
cation transport GO:0006812 399 0.097
Human
organic anion transport GO:0015711 137 0.097
regulation of anatomical structure size GO:0090066 178 0.083
regulation of system process GO:0044057 200 0.080
positive regulation of vasoconstriction GO:0045907 4 0.074
blood circulation GO:0008015 195 0.070
Zebrafish
carboxylic acid transport GO:0046942 100 0.068
muscle tissue development GO:0060537 308 0.062
Mouse
regulation of protein localization GO:0032880 231 0.057
Human Rat
regulation of cell cycle GO:0051726 281 0.057
Human
organic acid transport GO:0015849 101 0.057
cellular homeostasis GO:0019725 240 0.056
Mouse
regulation of transmembrane transport GO:0034762 128 0.054
Human
monocarboxylic acid metabolic process GO:0032787 191 0.052
cellular amino acid metabolic process GO:0006520 103 0.052
regulation of establishment of protein localization GO:0070201 181 0.051
Human Rat
response to organonitrogen compound GO:0010243 246 0.050
Mouse
muscle cell differentiation GO:0042692 261 0.050
anion transport GO:0006820 177 0.049
positive regulation of cell cycle GO:0045787 92 0.048
Human
epithelial cell proliferation GO:0050673 174 0.047
Mouse
cardiac chamber development GO:0003205 108 0.045
Mouse
cellular ketone metabolic process GO:0042180 84 0.045
macromolecule catabolic process GO:0009057 281 0.045
inorganic ion transmembrane transport GO:0098660 234 0.044
carnitine transmembrane transport GO:1902603 3 0.042
regulation of protein transport GO:0051223 163 0.042
Human Rat
transmission of nerve impulse GO:0019226 76 0.041
fertilization GO:0009566 127 0.040
negative regulation of cell proliferation GO:0008285 296 0.040
Mouse
regulation of kinase activity GO:0043549 249 0.040
actin cytoskeleton organization GO:0030036 220 0.040
Mouse
cellular modified amino acid metabolic process GO:0006575 63 0.039
muscle system process GO:0003012 141 0.039
oxidation reduction process GO:0055114 342 0.039
divalent inorganic cation transport GO:0072511 178 0.039
Human
aromatic compound catabolic process GO:0019439 286 0.038
regulation of intracellular transport GO:0032386 159 0.038
Human
l amino acid transport GO:0015807 32 0.037
regulation of membrane potential GO:0042391 192 0.036
organonitrogen compound biosynthetic process GO:1901566 192 0.036
Human
positive regulation of cellular ph reduction GO:0032849 2 0.035
regulation of blood circulation GO:1903522 93 0.035
positive regulation of epidermal growth factor activated receptor activity GO:0045741 2 0.034
Human
sensory perception of mechanical stimulus GO:0050954 107 0.034
skeletal muscle organ development GO:0060538 163 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.033
purine containing compound metabolic process GO:0072521 311 0.032
amine metabolic process GO:0009308 45 0.032
blastocyst development GO:0001824 80 0.032
cellular lipid metabolic process GO:0044255 323 0.032
action potential GO:0001508 78 0.031
neuronal action potential GO:0019228 54 0.031
protein targeting GO:0006605 143 0.031
regulation of homeostatic process GO:0032844 182 0.030
Mouse
response to organic cyclic compound GO:0014070 198 0.030
Mouse
synaptic transmission GO:0007268 329 0.030
regulation of neuron differentiation GO:0045664 281 0.030
Mouse
dna metabolic process GO:0006259 303 0.029
sensory perception of sound GO:0007605 97 0.029
striated muscle tissue development GO:0014706 293 0.029
Mouse
mitotic cell cycle GO:0000278 195 0.029
Human
organic hydroxy compound metabolic process GO:1901615 203 0.029
Mouse
circulatory system process GO:0003013 197 0.029
Zebrafish
purine ribonucleotide metabolic process GO:0009150 290 0.028
regulation of ion transport GO:0043269 215 0.028
Human
retina development in camera type eye GO:0060041 119 0.028
Mouse
angiogenesis GO:0001525 201 0.027
Human Mouse
heart contraction GO:0060047 93 0.027
regulation of cell projection organization GO:0031344 206 0.027
Mouse
membrane organization GO:0061024 245 0.027
Mouse
heart process GO:0003015 94 0.027
mammary gland lobule development GO:0061377 22 0.026
protein maturation GO:0051604 176 0.026
carnitine transport GO:0015879 3 0.026
inorganic cation transmembrane transport GO:0098662 207 0.026
cellular ion homeostasis GO:0006873 165 0.025
metal ion homeostasis GO:0055065 189 0.025
cellular chemical homeostasis GO:0055082 215 0.025
Mouse
divalent metal ion transport GO:0070838 172 0.025
Human
regulation of hormone levels GO:0010817 211 0.025
Mouse
protein catabolic process GO:0030163 221 0.025
heterocycle catabolic process GO:0046700 280 0.025
sensory perception GO:0007600 245 0.025
cellular nitrogen compound catabolic process GO:0044270 280 0.025
gland development GO:0048732 330 0.025
response to extracellular stimulus GO:0009991 127 0.025
Mouse
negative regulation of phosphate metabolic process GO:0045936 184 0.024
multicellular organismal signaling GO:0035637 91 0.024
organelle fission GO:0048285 170 0.024
Human
vascular process in circulatory system GO:0003018 62 0.024
epithelial tube morphogenesis GO:0060562 303 0.024
nucleotide metabolic process GO:0009117 332 0.024
positive regulation of nervous system development GO:0051962 221 0.023
wound healing GO:0042060 157 0.023
protein localization to organelle GO:0033365 185 0.023
regulation of leukocyte differentiation GO:1902105 159 0.023
leukocyte proliferation GO:0070661 172 0.023
regulation of cellular amine metabolic process GO:0033238 20 0.023
regulation of body fluid levels GO:0050878 162 0.023
negative regulation of phosphorus metabolic process GO:0010563 184 0.023
developmental growth involved in morphogenesis GO:0060560 138 0.023
Mouse
regulation of chloride transport GO:2001225 2 0.023
regulation of cell cycle process GO:0010564 160 0.022
Human
positive regulation of kinase activity GO:0033674 155 0.022
cardiac muscle tissue development GO:0048738 130 0.022
Mouse
regulation of mitotic cell cycle GO:0007346 126 0.022
Human
urate transport GO:0015747 1 0.022
regulation of cellular component biogenesis GO:0044087 181 0.022
cytoplasmic transport GO:0016482 234 0.022
carbohydrate homeostasis GO:0033500 128 0.022
Mouse
peptide transport GO:0015833 133 0.022
Mouse
intracellular protein transport GO:0006886 204 0.021
insulin secretion GO:0030073 89 0.021
Mouse
cellular amine metabolic process GO:0044106 44 0.021
cognition GO:0050890 149 0.021
regulation of transferase activity GO:0051338 263 0.021
rna processing GO:0006396 105 0.021
digestive tract development GO:0048565 190 0.021
Mouse
regulation of neurotransmitter levels GO:0001505 87 0.021
carbohydrate metabolic process GO:0005975 230 0.020
Human
nucleoside phosphate catabolic process GO:1901292 222 0.020
negative regulation of protein metabolic process GO:0051248 282 0.020
response to inorganic substance GO:0010035 96 0.020
protein processing GO:0016485 163 0.020
binding of sperm to zona pellucida GO:0007339 34 0.020
regulation of cellular amino acid metabolic process GO:0006521 5 0.020
locomotory behavior GO:0007626 195 0.020
regulation of organelle organization GO:0033043 289 0.020
Human Mouse
muscle contraction GO:0006936 101 0.019
chromatin organization GO:0006325 206 0.019
regulation of calcium ion transport GO:0051924 69 0.019
Human
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.019
mitotic cell cycle process GO:1903047 159 0.019
Human
renal system process GO:0003014 48 0.019
vasoconstriction GO:0042310 27 0.019
renal system development GO:0072001 225 0.019
Mouse
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
learning or memory GO:0007611 148 0.019
regulation of metal ion transport GO:0010959 106 0.019
Human
purinergic nucleotide receptor signaling pathway GO:0035590 3 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
glucose homeostasis GO:0042593 128 0.019
Mouse
regulation of ion transmembrane transport GO:0034765 119 0.019
Human
maintenance of location GO:0051235 89 0.018
organic hydroxy compound transport GO:0015850 93 0.018
reactive nitrogen species metabolic process GO:2001057 0 0.018
muscle cell development GO:0055001 133 0.018
response to acid chemical GO:0001101 111 0.018
Mouse
detection of stimulus GO:0051606 84 0.018
cellular response to lipid GO:0071396 145 0.018
hexose metabolic process GO:0019318 98 0.018
nucleocytoplasmic transport GO:0006913 139 0.018
sperm egg recognition GO:0035036 37 0.018
regulation of t cell activation GO:0050863 170 0.017
calcium ion transmembrane transport GO:0070588 85 0.017
positive regulation of cellular amine metabolic process GO:0033240 5 0.017
homeostasis of number of cells GO:0048872 210 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.017
regulation of proteolysis GO:0030162 164 0.017
amide transport GO:0042886 138 0.017
Mouse
response to amino acid GO:0043200 37 0.017
Mouse
regulation of epithelial cell proliferation GO:0050678 141 0.017
Mouse
monovalent inorganic cation homeostasis GO:0055067 33 0.017
mapk cascade GO:0000165 281 0.017
positive regulation of ion transport GO:0043270 65 0.017
oligopeptide transmembrane transport GO:0035672 4 0.017
mitotic chromosome condensation GO:0007076 1 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
lymphocyte proliferation GO:0046651 164 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
regulation of intracellular protein transport GO:0033157 82 0.017
Human
striated muscle contraction GO:0006941 45 0.016
organic cyclic compound catabolic process GO:1901361 295 0.016
nucleoside phosphate metabolic process GO:0006753 338 0.016
response to nutrient levels GO:0031667 109 0.016
Mouse
cell adhesion GO:0007155 329 0.016
cellular metal ion homeostasis GO:0006875 151 0.016
regulation of blood vessel size GO:0050880 56 0.016
positive regulation of secretion GO:0051047 130 0.016
nucleoside catabolic process GO:0009164 206 0.016
ribonucleoside catabolic process GO:0042454 206 0.016
anion transmembrane transport GO:0098656 71 0.016
neuromuscular process GO:0050905 99 0.016
regulation of tube size GO:0035150 57 0.016
negative regulation of cellular amine metabolic process GO:0033239 1 0.016
cellular carbohydrate metabolic process GO:0044262 119 0.016
t cell activation GO:0042110 289 0.016
multi multicellular organism process GO:0044706 109 0.016
blood vessel morphogenesis GO:0048514 285 0.015
Human Mouse
regulation of secretion GO:0051046 274 0.015
Human Mouse Rat
body fluid secretion GO:0007589 53 0.015
divalent inorganic cation homeostasis GO:0072507 138 0.015
nucleoside metabolic process GO:0009116 246 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
purine nucleotide metabolic process GO:0006163 302 0.015
mitochondrion organization GO:0007005 134 0.015
calcium ion transport GO:0006816 159 0.015
Human
plasma membrane organization GO:0007009 90 0.015
histamine uptake GO:0051615 1 0.015
chromosome organization involved in meiosis GO:0070192 39 0.015
mrna metabolic process GO:0016071 84 0.015
sterol homeostasis GO:0055092 45 0.015
regulation of cellular ph reduction GO:0032847 2 0.015
reactive oxygen species biosynthetic process GO:1903409 8 0.015
glycosyl compound metabolic process GO:1901657 246 0.015
regulation of feeding behavior GO:0060259 3 0.015
skeletal system development GO:0001501 356 0.015
Zebrafish Mouse
regulation of chromatin silencing GO:0031935 2 0.014
positive regulation of protein kinase activity GO:0045860 144 0.014
regulation of blood pressure GO:0008217 93 0.014
lipid homeostasis GO:0055088 63 0.014
leukocyte differentiation GO:0002521 342 0.014
i kappab kinase nf kappab signaling GO:0007249 85 0.014
striated muscle cell development GO:0055002 125 0.014
carboxylic acid biosynthetic process GO:0046394 86 0.014
tube formation GO:0035148 140 0.014
Mouse
regulation of cellular component size GO:0032535 121 0.014
fatty acid metabolic process GO:0006631 121 0.014
cellular protein catabolic process GO:0044257 155 0.014
meiosis i GO:0007127 60 0.014
cellular calcium ion homeostasis GO:0006874 119 0.014
norepinephrine transport GO:0015874 2 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
regulation of protein kinase activity GO:0045859 232 0.014
muscle tissue morphogenesis GO:0060415 53 0.014
Mouse
regulation of receptor activity GO:0010469 41 0.014
Human
endomembrane system organization GO:0010256 147 0.014
inflammatory response GO:0006954 244 0.014
determination of left right symmetry GO:0007368 80 0.014
Mouse
myelination GO:0042552 74 0.014
regionalization GO:0003002 337 0.014
Mouse
sequestering of metal ion GO:0051238 19 0.014
cation homeostasis GO:0055080 212 0.013
negative regulation of t cell apoptotic process GO:0070233 18 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
negative regulation of immune effector process GO:0002698 55 0.013
g protein coupled receptor signaling pathway GO:0007186 243 0.013
regulation of cell activation GO:0050865 289 0.013
amino acid betaine transport GO:0015838 3 0.013
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.013
apoptotic signaling pathway GO:0097190 306 0.013
camera type eye development GO:0043010 266 0.013
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.013
regulation of cytoplasmic transport GO:1903649 112 0.013
Human
ameboidal type cell migration GO:0001667 128 0.013
Mouse
monosaccharide metabolic process GO:0005996 106 0.013
membrane lipid biosynthetic process GO:0046467 32 0.013
calcium ion homeostasis GO:0055074 127 0.013
positive regulation of cell development GO:0010720 237 0.013
synapse organization GO:0050808 125 0.013
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.013
cofactor metabolic process GO:0051186 80 0.013
negative regulation of cellular component organization GO:0051129 194 0.013
Mouse
hormone secretion GO:0046879 128 0.013
Mouse
cellular response to hormone stimulus GO:0032870 150 0.013
purine containing compound catabolic process GO:0072523 213 0.013
extracellular structure organization GO:0043062 148 0.013
epithelial tube formation GO:0072175 130 0.013
Mouse
negative regulation of molecular function GO:0044092 258 0.013
neutral amino acid transport GO:0015804 13 0.013
regulation of ph GO:0006885 26 0.013
potassium ion homeostasis GO:0055075 4 0.013
compound eye development GO:0048749 1 0.012
mrna processing GO:0006397 63 0.012
response to peptide GO:1901652 136 0.012
lymphocyte activation involved in immune response GO:0002285 93 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
single fertilization GO:0007338 82 0.012
ribonucleotide metabolic process GO:0009259 291 0.012
defecation GO:0030421 1 0.012
purine nucleoside triphosphate metabolic process GO:0009144 226 0.012
pyridine containing compound catabolic process GO:0072526 4 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
protein modification by small protein conjugation GO:0032446 187 0.012
negative regulation of cell development GO:0010721 169 0.012
Mouse
cellular response to steroid hormone stimulus GO:0071383 33 0.012
sensory organ morphogenesis GO:0090596 242 0.012
Mouse
negative regulation of immune system process GO:0002683 209 0.012
protein localization to membrane GO:0072657 108 0.012
Mouse
negative regulation of cell activation GO:0050866 111 0.012
negative regulation of organelle organization GO:0010639 90 0.012
organonitrogen compound catabolic process GO:1901565 264 0.012
organophosphate biosynthetic process GO:0090407 122 0.012
lipid biosynthetic process GO:0008610 179 0.012
regulation of mapk cascade GO:0043408 248 0.012
mammary gland alveolus development GO:0060749 22 0.012
primary neural tube formation GO:0014020 95 0.012
Mouse
positive regulation of protein transport GO:0051222 93 0.012
Human
nucleoside phosphate biosynthetic process GO:1901293 79 0.012
multicellular organismal homeostasis GO:0048871 164 0.012
Mouse
sequestering of calcium ion GO:0051208 18 0.012
wnt signaling pathway GO:0016055 188 0.012
Mouse
regulation of lipid metabolic process GO:0019216 118 0.012
covalent chromatin modification GO:0016569 163 0.012
regulation of ion transmembrane transporter activity GO:0032412 54 0.012
pharynx development GO:0060465 1 0.012
nuclear division GO:0000280 158 0.012
Human
embryonic organ morphogenesis GO:0048562 276 0.012
Mouse
lymphocyte differentiation GO:0030098 242 0.011
cellular response to amino acid stimulus GO:0071230 29 0.011
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.011
cellular response to extracellular stimulus GO:0031668 81 0.011
regulation of renal sodium excretion GO:0035813 3 0.011
connective tissue development GO:0061448 179 0.011
Zebrafish Mouse
norepinephrine secretion GO:0048243 2 0.011
myeloid cell differentiation GO:0030099 233 0.011
urogenital system development GO:0001655 261 0.011
Mouse
progesterone metabolic process GO:0042448 4 0.011
phospholipid transfer to membrane GO:0006649 2 0.011
tube closure GO:0060606 91 0.011
Mouse
sulfur compound transport GO:0072348 9 0.011
midgut development GO:0007494 4 0.011
nuclear transport GO:0051169 139 0.011
tissue homeostasis GO:0001894 115 0.011
Mouse
cytokinetic process GO:0032506 2 0.011
negative regulation of protein modification process GO:0031400 163 0.011
modification dependent macromolecule catabolic process GO:0043632 133 0.011
forebrain development GO:0030900 302 0.011
Mouse
central nervous system neuron differentiation GO:0021953 162 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.011
vasodilation GO:0042311 28 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
cellular response to biotic stimulus GO:0071216 92 0.011
positive regulation of cell death GO:0010942 224 0.011
Mouse
cerebral cortex development GO:0021987 86 0.011
Mouse
regulation of transporter activity GO:0032409 57 0.011
negative regulation of lymphocyte apoptotic process GO:0070229 24 0.011
single organism nuclear import GO:1902593 95 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
adult locomotory behavior GO:0008344 91 0.011
response to insulin GO:0032868 100 0.011
negative regulation of t cell activation GO:0050868 65 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
rhythmic process GO:0048511 174 0.011
protein import GO:0017038 101 0.011
response to oxidative stress GO:0006979 123 0.011
t cell proliferation GO:0042098 120 0.011
skin development GO:0043588 220 0.011
Mouse
heart morphogenesis GO:0003007 178 0.011
Mouse
synapsis GO:0007129 34 0.011
gliogenesis GO:0042063 141 0.011
Mouse
chromatin modification GO:0016568 187 0.011
glycoprotein metabolic process GO:0009100 116 0.011
ribonucleotide catabolic process GO:0009261 208 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.010
regulation of protein targeting GO:1903533 61 0.010
Human
acetylcholine transport GO:0015870 2 0.010
regulation of cellular ketone metabolic process GO:0010565 66 0.010
regulation of heart contraction GO:0008016 77 0.010
negative regulation of protein transport GO:0051224 46 0.010
protein oligomerization GO:0051259 67 0.010
methionine transport GO:0015821 1 0.010
cellular response to organic cyclic compound GO:0071407 87 0.010
cellular alcohol metabolic process GO:0044107 3 0.010
protein modification by small protein conjugation or removal GO:0070647 207 0.010
endocrine process GO:0050886 39 0.010
skeletal muscle cell differentiation GO:0035914 66 0.010
positive regulation of protein phosphorylation GO:0001934 242 0.010
small molecule biosynthetic process GO:0044283 132 0.010
carbohydrate derivative catabolic process GO:1901136 231 0.010
regulation of vesicle mediated transport GO:0060627 139 0.010
intracellular receptor signaling pathway GO:0030522 74 0.010
blastocyst formation GO:0001825 33 0.010

Egf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
musculoskeletal system disease DOID:17 0 0.018
immune system disease DOID:2914 0 0.017
hematopoietic system disease DOID:74 0 0.017
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
connective tissue disease DOID:65 0 0.013
bone disease DOID:0080001 0 0.011