Mus musculus

0 known processes

Pold3

polymerase (DNA-directed), delta 3, accessory subunit

(Aliases: P68,2410142G14Rik,C85233,P66)

Pold3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to dna damage stimulus GO:0006974 207 0.759
dna metabolic process GO:0006259 303 0.447
dna repair GO:0006281 107 0.437
double strand break repair GO:0006302 48 0.390
intrinsic apoptotic signaling pathway GO:0097193 132 0.327
chromatin modification GO:0016568 187 0.311
apoptotic signaling pathway GO:0097190 306 0.252
recombinational repair GO:0000725 21 0.208
response to ionizing radiation GO:0010212 42 0.190
response to radiation GO:0009314 165 0.154
dna replication GO:0006260 52 0.153
chromatin organization GO:0006325 206 0.128
protein modification by small protein conjugation or removal GO:0070647 207 0.125
membrane organization GO:0061024 245 0.113
regulation of mitotic cell cycle phase transition GO:1901990 73 0.099
regulation of apoptotic signaling pathway GO:2001233 197 0.097
methylation GO:0032259 134 0.086
positive regulation of apoptotic process GO:0043065 217 0.084
purine nucleoside metabolic process GO:0042278 241 0.084
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.080
histone modification GO:0016570 159 0.079
cell cycle checkpoint GO:0000075 47 0.071
organonitrogen compound catabolic process GO:1901565 264 0.068
regulation of cellular amino acid metabolic process GO:0006521 5 0.068
cellular amine metabolic process GO:0044106 44 0.067
meiotic nuclear division GO:0007126 115 0.067
nucleobase containing small molecule metabolic process GO:0055086 352 0.066
regulation of organelle organization GO:0033043 289 0.062
regulation of cellular response to stress GO:0080135 159 0.061
cellular amino acid metabolic process GO:0006520 103 0.061
cellular ketone metabolic process GO:0042180 84 0.059
glycosyl compound metabolic process GO:1901657 246 0.057
ribonucleoside metabolic process GO:0009119 245 0.055
organelle fission GO:0048285 170 0.053
double strand break repair via homologous recombination GO:0000724 21 0.053
regulation of chromosome organization GO:0033044 83 0.053
mitotic cell cycle process GO:1903047 159 0.052
purine ribonucleoside metabolic process GO:0046128 241 0.050
cellular macromolecule catabolic process GO:0044265 206 0.050
amine metabolic process GO:0009308 45 0.049
nucleoside phosphate catabolic process GO:1901292 222 0.049
aromatic compound catabolic process GO:0019439 286 0.048
nucleotide metabolic process GO:0009117 332 0.048
retina development in camera type eye GO:0060041 119 0.048
protein catabolic process GO:0030163 221 0.047
regulation of cell cycle process GO:0010564 160 0.047
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.047
homeostasis of number of cells GO:0048872 210 0.045
response to extracellular stimulus GO:0009991 127 0.045
spermatogenesis GO:0007283 284 0.044
purine nucleotide catabolic process GO:0006195 211 0.043
heterocycle catabolic process GO:0046700 280 0.043
double strand break repair via nonhomologous end joining GO:0006303 10 0.043
negative regulation of protein metabolic process GO:0051248 282 0.043
cellular nitrogen compound catabolic process GO:0044270 280 0.043
ribonucleotide catabolic process GO:0009261 208 0.043
cellular protein complex assembly GO:0043623 116 0.042
protein modification by small protein conjugation GO:0032446 187 0.042
ribose phosphate metabolic process GO:0019693 291 0.041
regulation of cell cycle GO:0051726 281 0.040
mitotic recombination GO:0006312 3 0.039
positive regulation of cellular amine metabolic process GO:0033240 5 0.039
ribonucleoside triphosphate metabolic process GO:0009199 220 0.039
immunoglobulin production GO:0002377 73 0.039
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.039
macromolecule catabolic process GO:0009057 281 0.039
protein localization to organelle GO:0033365 185 0.038
positive regulation of programmed cell death GO:0043068 218 0.038
positive regulation of cell death GO:0010942 224 0.037
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.037
rna dependent dna replication GO:0006278 3 0.037
response to oxidative stress GO:0006979 123 0.036
purine ribonucleotide catabolic process GO:0009154 208 0.036
cellular protein catabolic process GO:0044257 155 0.036
regulation of chromatin modification GO:1903308 57 0.036
nucleus organization GO:0006997 45 0.035
positive regulation of apoptotic signaling pathway GO:2001235 95 0.035
regulation of protein complex assembly GO:0043254 83 0.035
spermatid development GO:0007286 108 0.035
protein maturation GO:0051604 176 0.035
purine containing compound metabolic process GO:0072521 311 0.035
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
cellular response to radiation GO:0071478 28 0.034
meiotic cell cycle GO:0051321 122 0.034
negative regulation of cellular component organization GO:0051129 194 0.034
mitotic cell cycle GO:0000278 195 0.033
dna dependent dna replication GO:0006261 24 0.033
peptidyl amino acid modification GO:0018193 336 0.033
regulation of histone h3 k36 methylation GO:0000414 1 0.033
covalent chromatin modification GO:0016569 163 0.033
dna modification GO:0006304 50 0.033
purine nucleoside catabolic process GO:0006152 205 0.032
maintenance of dna methylation GO:0010216 4 0.032
nucleoside triphosphate metabolic process GO:0009141 230 0.032
response to organic cyclic compound GO:0014070 198 0.032
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.031
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.031
regulation of hydrolase activity GO:0051336 246 0.031
cellular response to ionizing radiation GO:0071479 11 0.031
nucleoside metabolic process GO:0009116 246 0.031
positive regulation of hydrolase activity GO:0051345 148 0.031
mrna processing GO:0006397 63 0.030
engulfment of apoptotic cell GO:0043652 3 0.030
nucleoside phosphate metabolic process GO:0006753 338 0.029
purine nucleoside triphosphate catabolic process GO:0009146 203 0.029
ribonucleoside triphosphate catabolic process GO:0009203 199 0.029
establishment of protein localization to organelle GO:0072594 118 0.029
negative regulation of cellular protein metabolic process GO:0032269 247 0.028
dna recombination GO:0006310 92 0.028
positive regulation of histone h3 k4 methylation GO:0051571 5 0.028
establishment of organelle localization GO:0051656 122 0.028
nucleoside monophosphate metabolic process GO:0009123 85 0.028
production of molecular mediator of immune response GO:0002440 103 0.028
response to uv GO:0009411 44 0.028
regulation of histone h3 k4 methylation GO:0051569 12 0.027
purine nucleoside triphosphate metabolic process GO:0009144 226 0.027
positive regulation of organelle organization GO:0010638 128 0.027
negative regulation of histone h3 k9 methylation GO:0051573 4 0.027
male gamete generation GO:0048232 285 0.027
macromolecule methylation GO:0043414 120 0.027
negative regulation of cell proliferation GO:0008285 296 0.027
epithelial tube morphogenesis GO:0060562 303 0.027
regulation of cellular ketone metabolic process GO:0010565 66 0.026
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.026
peptidyl lysine modification GO:0018205 77 0.026
camera type eye development GO:0043010 266 0.026
epithelial tube formation GO:0072175 130 0.026
cell fate commitment GO:0045165 210 0.026
histone h3 k4 methylation GO:0051568 23 0.026
regulation of cell cycle g2 m phase transition GO:1902749 10 0.026
organic cyclic compound catabolic process GO:1901361 295 0.026
histone lysine methylation GO:0034968 50 0.026
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.025
regulation of cellular catabolic process GO:0031329 242 0.025
cell type specific apoptotic process GO:0097285 268 0.025
negative regulation of cell cycle phase transition GO:1901988 48 0.025
atp catabolic process GO:0006200 55 0.025
regulation of histone modification GO:0031056 56 0.025
regulation of histone methylation GO:0031060 30 0.025
negative regulation of cell cycle GO:0045786 123 0.024
response to light stimulus GO:0009416 135 0.024
regulation of cellular component biogenesis GO:0044087 181 0.024
gonad development GO:0008406 141 0.024
regulation of cell activation GO:0050865 289 0.024
lymphocyte proliferation GO:0046651 164 0.024
purine nucleotide metabolic process GO:0006163 302 0.022
histone methylation GO:0016571 71 0.022
protein acylation GO:0043543 64 0.022
leukocyte proliferation GO:0070661 172 0.022
gene silencing GO:0016458 38 0.022
response to lipopolysaccharide GO:0032496 128 0.022
cellular response to abiotic stimulus GO:0071214 56 0.022
purine containing compound catabolic process GO:0072523 213 0.022
b cell activation GO:0042113 161 0.022
positive regulation of cellular component biogenesis GO:0044089 94 0.022
germ cell development GO:0007281 185 0.022
negative regulation of chromosome organization GO:2001251 30 0.022
glycosyl compound catabolic process GO:1901658 206 0.021
organophosphate biosynthetic process GO:0090407 122 0.021
neuron death GO:0070997 154 0.021
myeloid cell differentiation GO:0030099 233 0.021
deoxyribonucleotide biosynthetic process GO:0009263 6 0.020
dna integrity checkpoint GO:0031570 28 0.020
regulation of neuron death GO:1901214 134 0.020
regulation of cell cycle phase transition GO:1901987 77 0.020
nucleoside triphosphate catabolic process GO:0009143 205 0.020
negative regulation of gene expression epigenetic GO:0045814 15 0.020
development of primary sexual characteristics GO:0045137 143 0.020
lymphocyte mediated immunity GO:0002449 139 0.020
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.020
cellular component assembly involved in morphogenesis GO:0010927 139 0.020
regulation of cellular amine metabolic process GO:0033238 20 0.020
blood vessel morphogenesis GO:0048514 285 0.019
regulation of circadian rhythm GO:0042752 58 0.019
regulation of nucleotide metabolic process GO:0006140 169 0.019
regulation of dna recombination GO:0000018 34 0.019
regulation of mitotic cell cycle GO:0007346 126 0.019
purine ribonucleotide metabolic process GO:0009150 290 0.019
protein processing GO:0016485 163 0.019
positive regulation of lymphocyte activation GO:0051251 140 0.019
cellular response to organonitrogen compound GO:0071417 145 0.019
organophosphate catabolic process GO:0046434 232 0.019
somatic diversification of immunoglobulins GO:0016445 43 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
purine nucleoside monophosphate metabolic process GO:0009126 81 0.019
response to acid chemical GO:0001101 111 0.019
mrna splicing via spliceosome GO:0000398 43 0.018
male meiosis i GO:0007141 16 0.018
positive regulation of protein complex assembly GO:0031334 45 0.018
digestive system development GO:0055123 200 0.018
anatomical structure homeostasis GO:0060249 145 0.018
chromosome organization involved in meiosis GO:0070192 39 0.018
negative regulation of cell cycle process GO:0010948 69 0.018
pore complex assembly GO:0046931 3 0.018
regulation of neuron apoptotic process GO:0043523 122 0.018
nuclear division GO:0000280 158 0.018
signal transduction by p53 class mediator GO:0072331 51 0.018
protein targeting GO:0006605 143 0.018
erythrocyte differentiation GO:0030218 88 0.018
regulation of cysteine type endopeptidase activity GO:2000116 65 0.018
somatic diversification of immune receptors via somatic mutation GO:0002566 8 0.017
dna hypermethylation GO:0044026 3 0.017
dna duplex unwinding GO:0032508 7 0.017
dna dependent dna replication maintenance of fidelity GO:0045005 3 0.017
regulation of proteolysis GO:0030162 164 0.017
heterochromatin organization GO:0070828 4 0.017
negative regulation of organelle organization GO:0010639 90 0.017
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.017
regulation of multi organism process GO:0043900 111 0.017
dna endoreduplication GO:0042023 4 0.017
adaptive immune response GO:0002250 155 0.017
dna damage checkpoint GO:0000077 26 0.017
leukocyte mediated immunity GO:0002443 174 0.017
organelle localization GO:0051640 179 0.017
negative regulation of protein modification process GO:0031400 163 0.017
gastrulation GO:0007369 116 0.017
fertilization GO:0009566 127 0.016
negative regulation of molecular function GO:0044092 258 0.016
regulation of transferase activity GO:0051338 263 0.016
telomere maintenance via telomerase GO:0007004 1 0.016
compound eye development GO:0048749 1 0.016
response to organonitrogen compound GO:0010243 246 0.016
positive regulation of protein modification process GO:0031401 299 0.016
digestive tract morphogenesis GO:0048546 147 0.016
regulation of gtp catabolic process GO:0033124 113 0.016
regulation of chromatin organization GO:1902275 57 0.016
neuron apoptotic process GO:0051402 142 0.016
oxidation reduction process GO:0055114 342 0.016
regulation of transcription by chromatin organization GO:0034401 0 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
maintenance of location GO:0051235 89 0.015
nuclear transport GO:0051169 139 0.015
protein ubiquitination GO:0016567 171 0.015
protein alkylation GO:0008213 81 0.015
purine ribonucleoside catabolic process GO:0046130 205 0.015
meiotic cell cycle checkpoint GO:0033313 2 0.015
response to purine containing compound GO:0014074 28 0.015
rna splicing via transesterification reactions GO:0000375 43 0.015
nucleoside phosphate biosynthetic process GO:1901293 79 0.015
centromere complex assembly GO:0034508 3 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
nucleotide catabolic process GO:0009166 217 0.015
regulation of leukocyte proliferation GO:0070663 121 0.015
immune effector process GO:0002252 321 0.015
nucleoside catabolic process GO:0009164 206 0.015
endomembrane system organization GO:0010256 147 0.015
regulation of protein kinase activity GO:0045859 232 0.015
protein methylation GO:0006479 81 0.015
purine nucleoside monophosphate catabolic process GO:0009128 58 0.015
endocytosis GO:0006897 168 0.015
ribonucleoside monophosphate metabolic process GO:0009161 80 0.015
connective tissue development GO:0061448 179 0.014
leukocyte differentiation GO:0002521 342 0.014
single organism nuclear import GO:1902593 95 0.014
negative regulation of mitotic cell cycle GO:0045930 58 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
angiogenesis GO:0001525 201 0.014
extrinsic apoptotic signaling pathway GO:0097191 126 0.014
positive regulation of chromatin modification GO:1903310 28 0.014
dna catabolic process GO:0006308 19 0.014
lateral inhibition GO:0046331 1 0.014
immunoglobulin mediated immune response GO:0016064 69 0.014
ameboidal type cell migration GO:0001667 128 0.014
ribonucleotide metabolic process GO:0009259 291 0.014
cofactor metabolic process GO:0051186 80 0.014
myeloid cell homeostasis GO:0002262 114 0.014
sensory organ morphogenesis GO:0090596 242 0.013
skin development GO:0043588 220 0.013
histone h3 k9 methylation GO:0051567 17 0.013
blastocyst development GO:0001824 80 0.013
response to steroid hormone GO:0048545 56 0.013
synapsis GO:0007129 34 0.013
regulation of double strand break repair via homologous recombination GO:0010569 2 0.013
response to inorganic substance GO:0010035 96 0.013
microtubule cytoskeleton organization GO:0000226 157 0.013
protein import into nucleus GO:0006606 95 0.013
rhythmic process GO:0048511 174 0.013
regulation of homeostatic process GO:0032844 182 0.013
somatic cell dna recombination GO:0016444 51 0.013
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.013
glycerolipid metabolic process GO:0046486 122 0.013
intracellular protein transport GO:0006886 204 0.013
negative regulation of phosphate metabolic process GO:0045936 184 0.013
positive regulation of histone methylation GO:0031062 16 0.013
mrna metabolic process GO:0016071 84 0.013
negative regulation of chromatin silencing GO:0031936 1 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
cell cycle g1 s phase transition GO:0044843 57 0.012
antibacterial peptide biosynthetic process GO:0002780 2 0.012
dna methylation GO:0006306 43 0.012
regulation of cell motility GO:2000145 236 0.012
morphogenesis of embryonic epithelium GO:0016331 159 0.012
skeletal system development GO:0001501 356 0.012
regulation of chromatin silencing GO:0031935 2 0.012
somatic hypermutation of immunoglobulin genes GO:0016446 7 0.012
regulation of membrane potential GO:0042391 192 0.012
regulation of myeloid cell differentiation GO:0045637 96 0.012
histone acetylation GO:0016573 41 0.012
multicellular organism growth GO:0035264 161 0.012
spermatid differentiation GO:0048515 115 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
dna conformation change GO:0071103 37 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
cellular response to organic cyclic compound GO:0071407 87 0.012
protein localization to nucleus GO:0034504 121 0.012
digestive tract development GO:0048565 190 0.012
regulation of secretion GO:0051046 274 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
isotype switching GO:0045190 36 0.012
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.012
regulation of dna damage checkpoint GO:2000001 3 0.012
regulation of kinase activity GO:0043549 249 0.012
ras protein signal transduction GO:0007265 77 0.012
rna processing GO:0006396 105 0.012
negative regulation of kinase activity GO:0033673 81 0.012
regulation of interleukin 1 alpha production GO:0032650 4 0.012
carbohydrate derivative biosynthetic process GO:1901137 183 0.012
cellular modified amino acid metabolic process GO:0006575 63 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
apoptotic mitochondrial changes GO:0008637 48 0.012
single fertilization GO:0007338 82 0.011
neural tube development GO:0021915 160 0.011
nitrogen compound transport GO:0071705 271 0.011
dna biosynthetic process GO:0071897 22 0.011
positive regulation of endopeptidase activity GO:0010950 43 0.011
coenzyme metabolic process GO:0006732 52 0.011
nuclear dna replication GO:0033260 3 0.011
membrane invagination GO:0010324 17 0.011
positive regulation of cytokine production GO:0001819 174 0.011
regulation of defense response GO:0031347 233 0.011
dna alkylation GO:0006305 43 0.011
deoxyribonucleotide metabolic process GO:0009262 14 0.011
positive regulation of immune effector process GO:0002699 107 0.011
regulation of cell division GO:0051302 76 0.011
regulation of nucleotide catabolic process GO:0030811 122 0.011
response to molecule of bacterial origin GO:0002237 143 0.011
positive regulation of histone modification GO:0031058 28 0.011
positive regulation of defense response to bacterium GO:1900426 1 0.011
locomotory behavior GO:0007626 195 0.011
positive regulation of cell cycle GO:0045787 92 0.011
positive regulation of nucleoside metabolic process GO:0045979 91 0.011
mitotic cell cycle checkpoint GO:0007093 31 0.011
cellular response to oxidative stress GO:0034599 76 0.011
response to amino acid GO:0043200 37 0.011
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 4 0.011
microtubule based process GO:0007017 236 0.011
negative regulation of transferase activity GO:0051348 85 0.011
regulation of endopeptidase activity GO:0052548 89 0.011
regulation of b cell activation GO:0050864 81 0.011
leukocyte apoptotic process GO:0071887 71 0.010
cell activation involved in immune response GO:0002263 126 0.010
cellular amide metabolic process GO:0043603 58 0.010
localization within membrane GO:0051668 4 0.010
positive regulation of cellular catabolic process GO:0031331 148 0.010
dna templated transcription termination GO:0006353 4 0.010
dna geometric change GO:0032392 7 0.010
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.010
adult behavior GO:0030534 135 0.010
mitochondrion organization GO:0007005 134 0.010
regulation of nucleoside metabolic process GO:0009118 130 0.010
zymogen activation GO:0031638 41 0.010
negative regulation of dna recombination GO:0045910 13 0.010
t cell proliferation GO:0042098 120 0.010
regulation of autophagy GO:0010506 30 0.010
internal protein amino acid acetylation GO:0006475 42 0.010

Pold3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.031
disease of cellular proliferation DOID:14566 0 0.031
central nervous system disease DOID:331 0 0.025
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
organ system cancer DOID:0050686 0 0.017
disease of mental health DOID:150 0 0.011
neurodegenerative disease DOID:1289 0 0.011