Mus musculus

56 known processes

Hdac3

histone deacetylase 3

(Aliases: AW537363)

Hdac3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle GO:0051726 281 0.197
cellular response to dna damage stimulus GO:0006974 207 0.183
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.144
macromolecule catabolic process GO:0009057 281 0.126
cellular protein catabolic process GO:0044257 155 0.122
dna metabolic process GO:0006259 303 0.118
ubiquitin dependent protein catabolic process GO:0006511 129 0.112
regulation of cell cycle process GO:0010564 160 0.108
protein catabolic process GO:0030163 221 0.103
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.098
positive regulation of cell death GO:0010942 224 0.095
modification dependent protein catabolic process GO:0019941 133 0.087
positive regulation of programmed cell death GO:0043068 218 0.081
covalent chromatin modification GO:0016569 163 0.077
gene silencing GO:0016458 38 0.072
chromatin modification GO:0016568 187 0.067
nuclear division GO:0000280 158 0.066
chromatin organization GO:0006325 206 0.065
response to organonitrogen compound GO:0010243 246 0.065
mitotic cell cycle GO:0000278 195 0.065
cellular macromolecule catabolic process GO:0044265 206 0.063
cytoplasmic transport GO:0016482 234 0.062
cellular lipid metabolic process GO:0044255 323 0.061
protein maturation GO:0051604 176 0.061
organelle fission GO:0048285 170 0.061
negative regulation of protein metabolic process GO:0051248 282 0.061
negative regulation of cell cycle GO:0045786 123 0.061
peptidyl amino acid modification GO:0018193 336 0.058
protein processing GO:0016485 163 0.057
histone modification GO:0016570 159 0.053
epithelial tube morphogenesis GO:0060562 303 0.050
regulation of mitotic cell cycle GO:0007346 126 0.050
regulation of cell activation GO:0050865 289 0.050
positive regulation of apoptotic process GO:0043065 217 0.049
regulation of protein maturation GO:1903317 96 0.047
aromatic compound catabolic process GO:0019439 286 0.047
meiotic nuclear division GO:0007126 115 0.046
transmembrane transport GO:0055085 412 0.045
modification dependent macromolecule catabolic process GO:0043632 133 0.044
embryonic organ morphogenesis GO:0048562 276 0.044
lymphocyte differentiation GO:0030098 242 0.043
cellular amino acid metabolic process GO:0006520 103 0.043
regulation of proteolysis GO:0030162 164 0.043
organelle assembly GO:0070925 177 0.042
Human
mitochondrion organization GO:0007005 134 0.042
organophosphate biosynthetic process GO:0090407 122 0.042
negative regulation of cellular component organization GO:0051129 194 0.041
negative regulation of protein processing GO:0010955 79 0.041
regulation of cellular catabolic process GO:0031329 242 0.040
nitrogen compound transport GO:0071705 271 0.040
negative regulation of cellular protein metabolic process GO:0032269 247 0.040
striated muscle tissue development GO:0014706 293 0.039
dna repair GO:0006281 107 0.039
endomembrane system organization GO:0010256 147 0.039
carbohydrate metabolic process GO:0005975 230 0.038
regulation of secretion by cell GO:1903530 249 0.037
mitotic cell cycle process GO:1903047 159 0.037
mrna metabolic process GO:0016071 84 0.037
apoptotic signaling pathway GO:0097190 306 0.037
nucleoside phosphate metabolic process GO:0006753 338 0.036
intrinsic apoptotic signaling pathway GO:0097193 132 0.036
meiotic cell cycle GO:0051321 122 0.035
nucleobase containing small molecule metabolic process GO:0055086 352 0.035
skeletal system development GO:0001501 356 0.035
regulation of cellular ketone metabolic process GO:0010565 66 0.034
negative regulation of proteolysis GO:0045861 74 0.034
monocarboxylic acid metabolic process GO:0032787 191 0.034
cellular ketone metabolic process GO:0042180 84 0.034
protein targeting GO:0006605 143 0.033
negative regulation of protein maturation GO:1903318 79 0.033
regulation of protein processing GO:0070613 96 0.033
histone h3 k9 dimethylation GO:0036123 4 0.033
organophosphate catabolic process GO:0046434 232 0.032
ribonucleotide metabolic process GO:0009259 291 0.032
methylation GO:0032259 134 0.032
purine ribonucleotide metabolic process GO:0009150 290 0.032
leukocyte differentiation GO:0002521 342 0.031
nucleotide metabolic process GO:0009117 332 0.031
regulation of cellular response to stress GO:0080135 159 0.030
Human
response to light stimulus GO:0009416 135 0.030
regulation of cellular amino acid metabolic process GO:0006521 5 0.030
intracellular protein transport GO:0006886 204 0.030
axonogenesis GO:0007409 274 0.030
chromatin silencing at rdna GO:0000183 3 0.029
synaptic transmission GO:0007268 329 0.029
ribonucleoside metabolic process GO:0009119 245 0.029
positive regulation of protein modification process GO:0031401 299 0.029
regulation of neuron differentiation GO:0045664 281 0.029
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.028
forebrain development GO:0030900 302 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.028
regulation of reproductive process GO:2000241 66 0.028
negative regulation of gene expression epigenetic GO:0045814 15 0.028
ion transmembrane transport GO:0034220 361 0.028
cell type specific apoptotic process GO:0097285 268 0.027
positive regulation of dna templated transcription elongation GO:0032786 2 0.027
heterocycle catabolic process GO:0046700 280 0.027
double strand break repair GO:0006302 48 0.027
regulation of lymphocyte activation GO:0051249 240 0.027
proteasomal protein catabolic process GO:0010498 98 0.026
tube formation GO:0035148 140 0.026
spermatogenesis GO:0007283 284 0.026
regulation of multi organism process GO:0043900 111 0.026
nucleoside metabolic process GO:0009116 246 0.026
membrane organization GO:0061024 245 0.025
response to inorganic substance GO:0010035 96 0.025
nucleoside triphosphate metabolic process GO:0009141 230 0.025
cation transport GO:0006812 399 0.025
sensory organ morphogenesis GO:0090596 242 0.025
neural tube development GO:0021915 160 0.025
muscle tissue development GO:0060537 308 0.025
nucleotide catabolic process GO:0009166 217 0.025
protein modification by small protein conjugation GO:0032446 187 0.025
organelle localization GO:0051640 179 0.024
fatty acid metabolic process GO:0006631 121 0.024
epithelial tube formation GO:0072175 130 0.024
regulation of secretion GO:0051046 274 0.024
microtubule nucleation GO:0007020 2 0.024
macromolecule methylation GO:0043414 120 0.023
carbohydrate derivative biosynthetic process GO:1901137 183 0.023
inorganic cation transmembrane transport GO:0098662 207 0.023
cellular response to hormone stimulus GO:0032870 150 0.023
cellular amine metabolic process GO:0044106 44 0.023
cellular response to lipid GO:0071396 145 0.023
cellular nitrogen compound catabolic process GO:0044270 280 0.023
skeletal muscle organ development GO:0060538 163 0.023
regulation of membrane potential GO:0042391 192 0.023
positive regulation of transferase activity GO:0051347 167 0.022
peptidyl lysine modification GO:0018205 77 0.022
regulation of apoptotic signaling pathway GO:2001233 197 0.022
carbohydrate catabolic process GO:0016052 32 0.022
cell substrate adhesion GO:0031589 130 0.022
purine nucleoside triphosphate metabolic process GO:0009144 226 0.022
nucleoside phosphate catabolic process GO:1901292 222 0.022
cation transmembrane transport GO:0098655 266 0.022
regulation of cellular amine metabolic process GO:0033238 20 0.022
regulation of establishment of protein localization GO:0070201 181 0.022
regulation of t cell activation GO:0050863 170 0.022
purine containing compound metabolic process GO:0072521 311 0.021
amine metabolic process GO:0009308 45 0.021
response to organic cyclic compound GO:0014070 198 0.021
inorganic ion transmembrane transport GO:0098660 234 0.021
rna interference GO:0016246 2 0.021
positive regulation of secretion GO:0051047 130 0.021
endocytosis GO:0006897 168 0.020
purine nucleotide metabolic process GO:0006163 302 0.020
purine ribonucleoside metabolic process GO:0046128 241 0.020
t cell activation GO:0042110 289 0.020
cellular carbohydrate metabolic process GO:0044262 119 0.020
microtubule based process GO:0007017 236 0.020
Human
negative regulation of cell development GO:0010721 169 0.020
protein dna complex disassembly GO:0032986 1 0.020
small molecule catabolic process GO:0044282 71 0.020
viral process GO:0016032 41 0.020
cellular homeostasis GO:0019725 240 0.019
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
establishment of protein localization to organelle GO:0072594 118 0.019
glycerophospholipid metabolic process GO:0006650 71 0.019
phospholipid metabolic process GO:0006644 87 0.019
negative regulation of cell cycle phase transition GO:1901988 48 0.019
purine nucleoside metabolic process GO:0042278 241 0.019
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.019
regulation of cell migration GO:0030334 219 0.019
apoptotic mitochondrial changes GO:0008637 48 0.018
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.018
purine ribonucleoside catabolic process GO:0046130 205 0.018
regulation of cell growth GO:0001558 91 0.018
regulation of cellular protein catabolic process GO:1903362 61 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
response to radiation GO:0009314 165 0.018
regulation of transferase activity GO:0051338 263 0.018
dna recombination GO:0006310 92 0.018
response to uv GO:0009411 44 0.018
regulation of ion transport GO:0043269 215 0.018
viral life cycle GO:0019058 36 0.018
negative regulation of phosphorylation GO:0042326 166 0.017
Human
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.017
camera type eye development GO:0043010 266 0.017
regulation of peptide transport GO:0090087 91 0.017
oxidation reduction process GO:0055114 342 0.017
placenta development GO:0001890 140 0.017
positive regulation of apoptotic signaling pathway GO:2001235 95 0.017
digestive system development GO:0055123 200 0.017
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.017
morphogenesis of embryonic epithelium GO:0016331 159 0.017
protein localization to organelle GO:0033365 185 0.017
neuron apoptotic process GO:0051402 142 0.017
protein modification by small protein conjugation or removal GO:0070647 207 0.017
regulation of dna damage checkpoint GO:2000001 3 0.017
regulation of leukocyte differentiation GO:1902105 159 0.016
pallium development GO:0021543 120 0.016
skeletal muscle cell differentiation GO:0035914 66 0.016
carbohydrate homeostasis GO:0033500 128 0.016
chromatin silencing GO:0006342 15 0.016
regulation of cell cycle phase transition GO:1901987 77 0.016
cytokine production GO:0001816 319 0.016
regulation of hydrolase activity GO:0051336 246 0.016
cellular component assembly involved in morphogenesis GO:0010927 139 0.016
regulation of protein catabolic process GO:0042176 108 0.016
negative regulation of neuron death GO:1901215 98 0.015
protein methylation GO:0006479 81 0.015
meiotic cell cycle process GO:1903046 77 0.015
oocyte axis specification GO:0007309 2 0.015
neuron death GO:0070997 154 0.015
learning or memory GO:0007611 148 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.015
posttranscriptional regulation of gene expression GO:0010608 155 0.015
cell adhesion GO:0007155 329 0.015
regulation of organelle organization GO:0033043 289 0.014
cell division GO:0051301 120 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.014
multi multicellular organism process GO:0044706 109 0.014
neural tube closure GO:0001843 90 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
organic cyclic compound catabolic process GO:1901361 295 0.014
ribose phosphate metabolic process GO:0019693 291 0.014
interspecies interaction between organisms GO:0044419 83 0.014
neuron migration GO:0001764 122 0.014
nucleoside phosphate biosynthetic process GO:1901293 79 0.014
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.014
dendrite development GO:0016358 115 0.014
gland development GO:0048732 330 0.014
regulation of neuron death GO:1901214 134 0.014
response to decreased oxygen levels GO:0036293 59 0.014
toxin transport GO:1901998 38 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
regulation of hormone levels GO:0010817 211 0.014
compound eye development GO:0048749 1 0.014
protein import into nucleus GO:0006606 95 0.014
response to peptide hormone GO:0043434 127 0.014
embryonic appendage morphogenesis GO:0035113 126 0.014
negative regulation of protein catabolic process GO:0042177 36 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.014
purine nucleoside monophosphate metabolic process GO:0009126 81 0.014
immune effector process GO:0002252 321 0.014
tube closure GO:0060606 91 0.013
purine nucleoside triphosphate catabolic process GO:0009146 203 0.013
insulin secretion GO:0030073 89 0.013
negative regulation of nervous system development GO:0051961 156 0.013
glycerophospholipid biosynthetic process GO:0046474 32 0.013
b cell differentiation GO:0030183 78 0.013
signal transduction in absence of ligand GO:0038034 55 0.013
nucleoside triphosphate catabolic process GO:0009143 205 0.013
dna modification GO:0006304 50 0.013
regulation of intracellular transport GO:0032386 159 0.013
limb morphogenesis GO:0035108 149 0.013
regulation of circadian rhythm GO:0042752 58 0.013
anatomical structure homeostasis GO:0060249 145 0.013
atp metabolic process GO:0046034 75 0.013
protein ubiquitination GO:0016567 171 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.013
t cell differentiation GO:0030217 174 0.013
positive regulation of nervous system development GO:0051962 221 0.013
nuclear export GO:0051168 34 0.013
acetylcholine transport GO:0015870 2 0.013
protein polyubiquitination GO:0000209 33 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
b cell activation GO:0042113 161 0.013
regulation of homeostatic process GO:0032844 182 0.013
rhythmic process GO:0048511 174 0.013
regulation of kinase activity GO:0043549 249 0.013
positive regulation of protein phosphorylation GO:0001934 242 0.013
dna replication GO:0006260 52 0.012
regulation of cell projection organization GO:0031344 206 0.012
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.012
nucleotide biosynthetic process GO:0009165 78 0.012
regulation of wnt signaling pathway GO:0030111 123 0.012
regulation of cell motility GO:2000145 236 0.012
maintenance of location GO:0051235 89 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.012
maternal determination of anterior posterior axis embryo GO:0008358 2 0.012
blood circulation GO:0008015 195 0.012
regulation of cytokine production GO:0001817 266 0.012
organonitrogen compound biosynthetic process GO:1901566 192 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.012
carbohydrate derivative catabolic process GO:1901136 231 0.012
sensory perception GO:0007600 245 0.012
regulation of protein targeting GO:1903533 61 0.012
cellular response to external stimulus GO:0071496 88 0.012
stem cell proliferation GO:0072089 117 0.012
negative regulation of cell activation GO:0050866 111 0.012
negative regulation of organelle organization GO:0010639 90 0.012
cognition GO:0050890 149 0.012
neural tube formation GO:0001841 108 0.012
regulation of nucleoside metabolic process GO:0009118 130 0.012
negative regulation of immune system process GO:0002683 209 0.012
regulation of mitotic cell cycle phase transition GO:1901990 73 0.012
glycerolipid metabolic process GO:0046486 122 0.012
negative regulation of growth GO:0045926 99 0.012
circulatory system process GO:0003013 197 0.012
negative regulation of cellular protein catabolic process GO:1903363 22 0.012
establishment of organelle localization GO:0051656 122 0.012
regulation of protein transport GO:0051223 163 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
regulation of protein localization GO:0032880 231 0.012
establishment of vesicle localization GO:0051650 81 0.011
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 3 0.011
negative regulation of molecular function GO:0044092 258 0.011
positive regulation of cell projection organization GO:0031346 95 0.011
virion assembly GO:0019068 1 0.011
positive regulation of secretion by cell GO:1903532 114 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
embryonic epithelial tube formation GO:0001838 130 0.011
organic hydroxy compound metabolic process GO:1901615 203 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
dna damage response signal transduction resulting in transcription GO:0042772 2 0.011
multicellular organismal signaling GO:0035637 91 0.011
urogenital system development GO:0001655 261 0.011
protein secretion GO:0009306 111 0.011
positive regulation of cell activation GO:0050867 158 0.011
glycosyl compound metabolic process GO:1901657 246 0.011
positive regulation of neuron differentiation GO:0045666 141 0.011
cellular response to nutrient levels GO:0031669 64 0.011
histone h3 k9 trimethylation GO:0036124 6 0.011
ras protein signal transduction GO:0007265 77 0.011
generation of precursor metabolites and energy GO:0006091 103 0.011
anion transport GO:0006820 177 0.011
spermatid development GO:0007286 108 0.011
regulation of autophagic vacuole assembly GO:2000785 4 0.011
positive regulation of neuron projection development GO:0010976 79 0.011
regulation of response to wounding GO:1903034 189 0.011
glycoprotein metabolic process GO:0009100 116 0.010
nuclear transport GO:0051169 139 0.010
protein palmitoylation GO:0018345 14 0.010
protein localization to nucleus GO:0034504 121 0.010
cellular response to extracellular stimulus GO:0031668 81 0.010
lymphocyte proliferation GO:0046651 164 0.010
negative regulation of cellular catabolic process GO:0031330 47 0.010
regulation of lipid metabolic process GO:0019216 118 0.010
organism emergence from protective structure GO:0071684 4 0.010
posttranscriptional gene silencing by rna GO:0035194 10 0.010
male gamete generation GO:0048232 285 0.010
multicellular organism growth GO:0035264 161 0.010
cardiac chamber development GO:0003205 108 0.010
inflammatory response GO:0006954 244 0.010
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.010
peptide transport GO:0015833 133 0.010
hatching GO:0035188 4 0.010
amide transport GO:0042886 138 0.010

Hdac3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013